BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2016-00026 A Randomized Phase 3 Open Label Study of Nivolumab vs Temozolomide Each in Combination with Radiation Therapy in Newly Diagnosed Adult Subjects with Unmethylated MGMT (tumor O-6-methylguanine DNA meth More ... clinical trial drugs phase 3 multicentric B Dr. Patrick Roth Bristol-Myers Squibb International Corporation UniversitätsSpital Zürich, Klinik für Neurologie, Zürich
Hôpital Cantonal Universitaire Département Médecine Oncologie, Rue Gabrielle Perret-Gentil 4, 1211 Genève, Geneva
Centre Hospitalier Universita More ...
Kantonale Ethikkommission Zürich Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) 15.06.2016 Study has ended
2016-00025 Efficacy of two human fibrinogen concentrates to treat dilutional coagulopathy. An in vitro study. non clinical, involving persons monocentric A Priv. Doz. Dr. Thorsten Haas University Children's Hospital Zurich Unilabs Zürich Hufgasse 17 - CH-8008 Zürich, Zürich
Kantonale Ethikkommission Zürich 19.04.2016 Study has ended
2016-00023 Verticality perception – effects of prolonged roll-tilt in healthy human subjects clinical trial other clinical trials monocentric A Prof. Dr. med. Dominik Straumann Klinik für Neurologie, UniversitätsSpital Zürich Klinik für Neurologie, Universitätsspital Zürich, Zürich
Kantonale Ethikkommission Zürich 04.05.2016
2016-00022 Impact of Procedural Changes in Laparoscopic Gastric Bypass on Perioperative Morbidity and assessment of changes in eating behavior and quality of life after bariatric surgery: Retrospective Analysis personal data/biological material monocentric Dr.med. Diana Vetter Klinik für Viszeral- und Transplantationschirurgie Klinik für Viszeral- und Transplantationschirurgie, UniversitätsSpital Zürich, Zürich
Kantonale Ethikkommission Zürich 24.11.2016
2016-00021 Perinatal depression: chronobiology, sleep related risk factor and light therapy clinical trial medical devices monocentric A Dr. med. Mauro Manconi Centro del sonno ed epilessia Ospedale Regionale di Lugano, Lugano
Comitato etico cantonale Ticino 31.05.2016 Study has ended
2016-00020 An international multi-center, open-label study to evaluate safety, tolerability, biodistribution, dosimetry and preliminary efficacy of 177Lu-OPS201 for the therapy of somatostatin receptor positive More ... clinical trial drugs phase 1/2 monocentric C Prof. Dr. Dr. Damian Wild Universitätsspital Basel University Hospital Basel, Department of Nuclear Medicine, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 06.04.2016 Study has ended
2016-00018 Interaction between intravenous magnesium sulphate and neostigmine or sugammadex for the reversal of a rocuronium-induced neuromuscular block
A randomized, double blinded, electrophysiological study
More ...
clinical trial drugs phase 4 multicentric C Dr. Christoph Czarnetzki Geneva University Hospitals University Hospitals of Geneva, Geneva
Department of Anesthesiology and Intensive Care Medicine, Valais Hospital, 1951 Sion
Commission Cantonale d'éthique de la recherche Genève (CCER) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 02.02.2017
2016-00017 Extensibility of the hamstrings: comparison of passive stretching and treatment with Roller-Massager. clinical trial other clinical trials monocentric A Marco Barbero Scuola universitaria professionale della Svizzera italiana (SUPSI) SUPSI, Manno
Comitato etico cantonale Ticino 11.02.2016 Study has ended
2016-00016 Early surgery in prone position in patients undergoing non-operative management for splenic and liver injuries personal data/biological material monocentric PD Dr. med. Beat Schnüriger UVCM, Inselspital Bern Universitätsklinik für Viszerale Chirurgie und Medizin, Inselspital Bern, Bern
Kantonale Ethikkommission Bern 16.06.2016
2016-00015 Tako-Tsubo Cardiomyopathy and Cardiac Syndrome X: a study on the brain-heart interactions in two orphan cardiac diseases. (BRAINHEART study) non clinical, involving persons monocentric A Dr. med. Mattia Cattaneo Department of Cardiology and Division of Cardiovascular Research, Ospedale Regionale di Bellinzona e Valli - San Giovanni Hospital Division of Cardiovascular Research, Ospedale Regionale di Bellinzona e Valli - San Giovanni Hospital, CH - 6500 Bellinzona
Comitato etico cantonale Ticino 29.03.2016
2016-00014 Non-interventional long term study for observation of treatment with LEMTRADA® in active relapsing-remitting MS: Patient management and monitoring in clinical routine care
(Nicht-interventionelle Lan More ...
non clinical, involving persons multicentric A Dr. Anke Salmen sanofi-aventis (suisse) ag Inselspital - Universitätsklinik für Neurologie, Bern
Neurologie Oberaargau, 4900 Langenthal
Neurologie am Löwenplatz - Löwencenter, 6004 Luzern
Kantonsspital Aarau KG, 5001 Aarau
Neurologische Praxis More ...
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... 17.05.2016 Study has ended
2016-00013 A Randomised, Double-Blind, Placebo-Controlled Multicentre Clinical Trial of
Inhaled Molgramostim in Autoimmune Pulmonary AlveoLAr Proteinosis Patients “IMPALA”
clinical trial drugs phase 2 monocentric C Dr Romain Lazor Savara ApS Lausanne University Hospital, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 27.04.2016 Study has ended
2016-00011 Health-related quality of life after frequent and rare fractures in children non clinical, involving persons monocentric A PD Dr. med. Thoralf R. Liebs Inselspital, Klinik für Kinderchirurgie Inselspital Bern University Hospital, Bern
Kantonale Ethikkommission Bern 10.05.2016 yes
2016-00010 QUALITY ASSESSMENT IN HEPATIC HEMODYNAMIC PROCEDURES AT INSELSPITAL: RADIATION EXPOSURE, IODINE CONTRAST USE AND PROCEDURE RELATED COMPLICATIONS personal data/biological material monocentric Dr. Annalisa Berzigotti Hepatologie, UVCM, Inselspital, Berne UVCM Hepatologie, Inselspital, Bern
Kantonale Ethikkommission Bern 27.01.2016
2016-00009 ABSES.
The Abdominal Sepsis Study:
Epidemiology of Etiology and Outcome
non clinical, involving persons monocentric A PD Dr. Alexander Dullenkopf Kantonsspital Frauenfeld, Institut für Anästhesie und Intensivmedizin KS Frauenfeld, Institut für Anästhesie und Intensivmedizin, Frauenfeld
Ethikkommission Ostschweiz (EKOS) 18.01.2016 Study has ended
2016-00008 Dose-intensified Image-guided Fractionated Stereotactic Body Radiation Therapy for Painful Spinal Metastases versus Conventional Radiation Therapy: a Randomised Controlled Trial (DOSIS RCT) clinical trial other clinical trials multicentric A Prof. Dr. Matthias Guckenberger Klinik für Radio-Onkologie, USZ UniversitätsSpital Zürich, Zürich
Inselspital Bern, Bern
Universitätsspital Basel, Basel
Kantonsspital Aarau, Aarau
Hôpitaux Universitaires Genève (HUG), Genève
Clinique des Grangettes, Genève
Kantons More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche G More ... 07.04.2016
2016-00007 Contribution circulatoire et ventilatoire de la pompe diaphragmatique à l’exercice en hypoxie. non clinical, involving persons monocentric A Grégoire Millet / Professeur Associé Université de Lausanne - Département de Physiologie - Faculté de biologie et médecine - Institut des Sciences du Sport (ISSUL) Université de Lausanne Faculté de biologie et de médecine Institut des Sciences du Sport (ISSUL), Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 12.04.2016 Study has ended
2016-00006 Amount of foraminal lumbar stenosis and the relation to clinical symptoms and response to periradicular infiltration – Introduction of the “melting sign” personal data/biological material monocentric PD Dr. med. Mazda Farshad Universitätsklinik Balgrist Universitätsklinik Balgrist, Zürich
Kantonale Ethikkommission Zürich 17.02.2016
2016-00004 A Phase 2 Study to Evaluate the Efficacy and Tolerability of Debio 1562 in
Combination with Rituximab in Patients with Relapsed and/or Refractory
Diffuse Large B-Cell Lymphoma and Other Forms of No More ...
clinical trial drugs phase 2 monocentric C Dr. Anastasios Stathis Debiopharm international S.A. Istituto Oncologico della Svizzera Italiana, Ospedale Regionale Bellinzona e Valli, Bellinzona
Comitato etico cantonale Ticino 15.04.2016 Study has ended
2016-00003 CLCZ696B2401 -A multicenter, randomized, open label, parallel group study comparing pre-discharge and posT-discharge tReatment initiation with LCZ696 in heArt failure patieNtS with reduced ejectIon-fr More ... clinical trial drugs phase 4 multicentric B Prof. Dr. med Christian Müller Novartis Pharma Schweiz AG Universitätsspital Basel, Basel
HUG - Service de Cardiologie, Genève
Ethikkommission Nordwest- und Zentralschweiz EKNZ Commission Cantonale d'éthique de la recherche Genève (CCER) 25.04.2016 Study has ended