| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-01162 | MentalGut – A Cohort Study of the Faecal Microbiome in Patients Suffering from Depression, Anxiety, or Schizophrenia in Switzerland | non clinical, involving persons | multicentric | A | Prof. Dr. med. Reiner Wiest | Inselspital Bern |
Universitätsklinik für Viszerale Chirurgie und Medizin, Inselspital, Bern Universitäre Psychiatrische Dienste (UPD) Bern, Bern |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 29.07.2025 | |||||
| 2025-01161 | Recurrence rate of cutaneous melanoma, detection modalities and number needed to biopsy for subsequent melanoma between 2014-2023: A retrospective study | personal data/biological material | monocentric | PD Dr. med. Joanna Mangana | Universitätsspital Zürich |
University Hospital Zurich, Zurich, Switzerland |
Kantonale Ethikkommission Zürich | 14.11.2025 | |||||||
| 2025-01159 | First Ray Instability Score in patients with Hallux Valgus: psychometric properties and associated factors | non clinical, involving persons | multicentric | A | Pr. Stéphane Armand | UNIGE |
HUG, Geneva Centre ASSAL, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Commission Cantonale d'éthique de la recherche Genève (CCER) | 18.11.2025 | |||||
| 2025-01158 | Fish&CheckNet - Implementazione di un Algoritmo di Intelligenza Artificiale per il Matching delle Scansioni TC Facciali in Identificazione Forense | deceased persons | monocentric | MR. Ermidio Rezzonico | Imaging Institute of Southern Switzerland |
Imaging Insitute of Southern Switzerland, Lugano |
Comitato etico cantonale Ticino | 02.09.2025 | |||||||
| 2025-01157 | Ialuril prefill Therapy in Recurrent Urinary Tract Infections Effect on UTI incidences and need for Antibiotics | personal data/biological material | multicentric | Prof. Dr. med. Cornelia Betschart | USZ |
Universitätsspital, Gynäkologie, Zürich Frauenklinik, Grabs |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS) | 24.10.2025 | ||||||
| 2025-01156 | Arterial to central-venuous CO2-gap as prognostic parameter in critically ill patients | personal data/biological material | monocentric | Prof. Dr. Alexander Dullenkopf | Spital Thurgau Frauenfeld |
Spital Thurgau Frauenfeld, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 19.06.2025 | |||||||
| 2025-01155 | A retrospective registry study to assess Transthyretin Amyloid cardiomyopathy (ATTR-CM) disease burden in Switzerland | personal data/biological material | monocentric | Prof. Dr. med. Christoph Gräni | Inselspital, Universitätsspital Bern |
Inselspital, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 18.09.2025 | |||||||
| 2025-01154 | Impact of chronic non-medical prescription opioid use on social cognition | non clinical, involving persons | monocentric | A | Prof. Dr. rer. nat. Boris B. Quednow | University Hospital of Psychiatry Zurich (PUK) |
University Hospital of Psychiatry Zurich (PUK), University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 05.09.2025 | ||||||
| 2025-01153 | Project Title: Climate change related exposome of Swiss outdoor workers: Swiss contribution to the EU INTERCAMBIO project, Work package 2, Task 2.1 | non clinical, involving persons | monocentric | A | Prof. Irina Guseva Canu | Unsianté - Santé, travail |
Unisanté, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.08.2025 | ||||||
| 2025-01152 | Use of [18F]FET PET-MRI to improve detection of pituitary adenomas in Cushing’s disease: a prospective diagnostic study - The FIND Study | clinical trial | drugs | phase 4 | monocentric | A | Prof. Emanuel Christ | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.10.2025 | ||||
| 2025-01151 | Days alive and out of hospital within 30 days of patients presenting with atrial fibrillation with rapid ventricular response at Luzerner Kantonsspital Emergency Department – retrospective review | personal data/biological material | monocentric | Prof. Dr. med. Michael Christ | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.07.2025 | |||||||
| 2025-01150 | La césarienne douce: un bénéfice pour tous? | non clinical, involving persons | monocentric | A | Dresse Corinne Grandjean | Hôpital cantonal Fribourg |
HFR Fribourg, Villars-sur-Glâne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.03.2026 | ||||||
| 2025-01149 | Phase 2 Platform Trial to Assess the Efficacy and Safety of Long-acting Antibodies as Single Agents and in Combinations for Moderately to Severely Active Ulcerative Colitis | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. med. Pascal Juillerat | Spyre Therapeutics, Inc. |
Intesto BE, Bern Clarunis – Universitäres Bauchzentrum Basel Universitätsspital Basel Petersgraben 4, 4031 Basel HOCH Health Ostschweiz Kantonsspital St.Gallen Gastroenterologie/Hepatologie Haus 03, 1 More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS) | 24.10.2025 | |||
| 2025-01147 | Relative Afferent Pupillary Defect (RAPD) neoscore validation | personal data/biological material | monocentric | Bruno Hauser | machineMD AG |
machineMD AG, Bern |
Kantonale Ethikkommission Bern | 26.08.2025 | |||||||
| 2025-01145 | Efficacy of Port-wine birthmarks treatment with a new long-pulse KTP laser: a retrospective study | personal data/biological material | monocentric | Dr. Paula Bonavia, MD | Margarethenklinik, University Hospital of Basel |
Margarethenklinik, University Hospital of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.07.2025 | |||||||
| 2025-01143 | Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Corinne Widmer | Stichting Hemato-Oncologie voor Volwassenen Nederland (HOVON) |
University Hospital Basel, Basel Inselspital Bern, Bern IOSI, Ospedale Regionale, Bellinzona Universitätsspital Zürich, Zurich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 16.10.2025 | |||
| 2025-01142 | KiBa – Kids in Balance: Clinical evaluation of the Pediatric Balance Scale assessment for a reliable use with impaired children | non clinical, involving persons | monocentric | A | MSc. Physiotherapist, Zorica Suica | Reha Rheinfelden |
Reha Rheinfelden, Rheinfelden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.06.2025 | yes | |||||
| 2025-01141 | Implant Accuracy of 3D Printed PEEK, Barium Sulphate PEEK and Titanium for Orbital Reconstruction | deceased persons | monocentric | MSc. Jokin Zubizarreta Oteiza | Univeristy Hospital Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.09.2025 | |||||||
| 2025-01140 | Effects of Weight loss Surgery and Obesity Management Medication on Patient-Reported Outcomes, Efficacy, and Safety in Grade II-III Obesity | non clinical, involving persons | monocentric | A | Dr. med. Pauline Aeschbacher | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 17.09.2025 | ||||||
| 2025-01138 | Arts and culture on prescription. The impact of cultural prescription on the health of the elderly population living in the Lugano region – A pilot project. | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Luca Gabutti | Università della Svizzera italiana / EOC |
Institute of Family Medicine, Lugano |
Comitato etico cantonale Ticino | 06.10.2025 | |||||