| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-00303 | The optimal off-the-shelf stock of Castor single branched TEVARs for the treatment of acute type B aortic dissections - an anatomical feasibility study | personal data/biological material | monocentric | PD Dr. med. Benedikt Reutersberg | USZ |
University hospital Zurich (USZ), Zurich |
Kantonale Ethikkommission Zürich | 12.04.2024 | |||||||
| 2024-00302 |
Impact of Patient Blood Management (PBM) at the Schulthess Clinic A quality assurance and quality control project in major orthopaedic and spine surgery |
personal data/biological material | monocentric | Prof. Dr. Christoph Hofer | Schulthess Klinik |
Schulthess Klinik, Zürich |
Kantonale Ethikkommission Zürich | 16.04.2024 | |||||||
| 2024-00301 | Experimental assessment of the mechanical stability of bone density-optimized pedicle screw trajectories compared to standard clinical placement | deceased persons | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, zürich |
Kantonale Ethikkommission Zürich | 28.03.2024 | |||||||
| 2024-00300 | Maternal and Neonatal outcomes in Association with midwifery Staffing - a causal inference framework | personal data/biological material | monocentric | Prof Dr Michael Simon | University of Basel |
Uniersity of Basel, Institute of Nursing Science, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.02.2024 | |||||||
| 2024-00298 | Exploring the added diagnostic value of arterial spin labeling in pediatric focal lesional epilepsy | personal data/biological material | monocentric | Prof. Dr. med. Georgia Ramantani, PhD | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 26.03.2024 | |||||||
| 2024-00296 | An open-label extension trial of the long-term safety and efficacy of BI 1015550 taken orally in patients with idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF) (FIBRONEER™- More ... | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. med. Katrin Hostettler Haack | Boehringer Ingelheim International GmbH |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.07.2024 | ||||
| 2024-00295 | Pre-transplant frailty in lung transplant recipients: does it affect post-transplant outcomes? | personal data/biological material | monocentric | PhD.Dr.med. René Hage | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 28.03.2024 | |||||||
| 2024-00294 | The quantity of lower muscle as a promising prognostic factor for overall survival in bone and soft tissue sarcoma patients | personal data/biological material | monocentric | PD Dr. med. Daniel Müller | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 17.09.2024 | |||||||
| 2024-00293 | Personalized simulations of a novel exercise-based vertebral growth modulation approach for minimizing curve progression in adolescent idiopathic scoliosis | non clinical, involving persons | multicentric | A | Prof. Dr. Stefan Schmid | Bern University of Applied Sciences |
Bern University of Applied Sciences, Bern University Hospital of Bern (Inselspital), Bern University Children's Hospital of Basel (UKBB), Basel |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 23.05.2024 | yes | ||||
| 2024-00292 | The relationship between the distance from the tumor to major blood vessels regarding prognosis of deep high grade soft tissue sarcomas | personal data/biological material | monocentric | PD Dr. med. Daniel Müller | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 28.05.2024 | |||||||
| 2024-00291 | Vergleichsmethoden der subjektiven Refraktion in Zeiten des digitalen Wandels | non clinical, involving persons | monocentric | A | Prof. Dr. Daniela Nosch | Institut für Optometrie, Hochschule für Technik, FHNW |
Institut für Optometrie, Hochschule für Technik, FHNW, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.02.2024 | ||||||
| 2024-00290 | Analysis of the Cortical thickness index of the proximal femoral – intra-individual differences in patients with a proximal femoral fracture | personal data/biological material | monocentric | MD, Method Kabelitz | Stadtspital Zürich |
Clinic for Orthopaedics, Hand Surgery and Trauma Surgery, Stadtspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 12.04.2024 | |||||||
| 2024-00289 | Postoperative outcomes following peroneus brevis muscle flap reconstruction of lateral malleolus: retrospective study. | personal data/biological material | monocentric | PD Dr Carlo M. Oranges, MD, PhD |
Department of Plastic, Reconstructive, and Aesthetic Surgery, Geneva University Hospitals, Geneva University, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.03.2024 | ||||||||
| 2024-00286 | A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Zilebesiran Used as Add-on Therapy in Adult Patients With High Cardiovascular Risk and Hyperten More ... | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. med. Annina Vischer | Alnylam Pharmaceuticals, Inc. |
Medizinische Poliklinik, Universitätsspital Basel, Basel Luzerner Kantonsspital LUKS, Luzern Hôpitaux Universitaires de Genève, Genève Centre Hospitalier Universitaire Vaudois, Lausanne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) | 15.05.2024 | |||
| 2024-00285 | Development of an alveolar organoid model to investigate antimicrobial resistance and bacterial pathogenesis | personal data/biological material | monocentric | Prof. Spasenija Savic Prince | University of Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.03.2024 | |||||||
| 2024-00284 | Characterization of Macrophages and Dendritic cells subsets in granulomatous and non-granulomatous (inflammatory) skin disease. | personal data/biological material | monocentric | Prof. Dr. med. Werner Kempf | Kempf und Pfaltz Histologische Diagnostik |
Kempf und Pfaltz Histologische Diagnostik AG, Zürich |
Kantonale Ethikkommission Zürich | 25.06.2024 | |||||||
| 2024-00283 | EVALUATION OF THE SOFTWARE TOOLS FOR FETAL DOSE ASSESSEMENT FROM CT EXAMINATIONS | personal data/biological material | multicentric | Ms. Anja Stüssi | Unispital Zurich |
Unispital Zurich, Zurich University Hospital of Geneva, Geneva CHUV, Lausanne |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) | 20.08.2024 | ||||||
| 2024-00282 | Effectiveness of Quality Improvement Approach on outcomes of cardiac arrest in pediatric intensive care unit – a retrospective single-institution observational research project | personal data/biological material | monocentric | Prof. Luregn Schlapbach | Universitäts-Kinderspital Zürich – Eleonorenstiftung |
Universitäts-Kinderspital Zürich – Eleonorenstiftung, Zürich |
Kantonale Ethikkommission Zürich | 19.04.2024 | |||||||
| 2024-00281 |
SAKK 16/xx_not_operated Outcome of patients with resectable stage III NSCLC intended for neoadjuvant treatment who did not undergo surgery. Retrospective analysis of the trials SAKK 16/96, 16/00, 1 More ... |
personal data/biological material | monocentric | Dr. med. David König | SAKK |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.04.2024 | |||||||
| 2024-00278 | Outcome-defining parameters of patients with severe neutropenia/agranulocytosis in the ICU setting | personal data/biological material | monocentric | PD Dr. med. Daniel Hofmänner | University Hospital Zurich |
Institute of Intensive Care Medicine, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 23.04.2024 | |||||||