BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2016-00067 Molecular heterogeneity of breast cancer – in-vivo and in-vitro analysis non clinical, involving persons monocentric A Dr. med. Savas Soysal University Hospital of Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 14.03.2016
2016-00066 (20120123) Double-blind, Randomized, Multicenter, Placebo-controlled, Parallel Group
Study to Characterize the Efficacy, Safety, and Tolerability of 24 Weeks of
Evolocumab for Low Density Lipoprotei More ...
clinical trial drugs phase 3 multicentric B Prof. André Miserez AMGEN Inc. Diagene Incorporated, 4153 Reinach
Hopitaux Universitaires de Geneve, Genève
Ethikkommission Nordwest- und Zentralschweiz EKNZ Commission Cantonale d'éthique de la recherche Genève (CCER) 25.05.2016 yes Study has ended
2016-00065 SaltoTM and Salto TalarisTM Total Ankle Replacement: Prospective Study of 302 Patients with a 1 to 14 year Follow-Up personal data/biological material multicentric MD Halah KUTAISH Clinique La Colline Clinique La Colline, Geneva
CHUV, Lausanne
Commission Cantonale d'éthique de la recherche Genève (CCER) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 29.03.2016
2016-00064 Breast cancer diagnosis and characterization with current breast imaging methods: a retrospective evaluation. personal data/biological material monocentric PD Dr. med. Dr. sc. hum. Andreas Boss Institut für Interventionelle und diagnostische Radiologie USZ Institute of Diagnostic and Interventional Radiology, Zürich
Kantonale Ethikkommission Zürich 16.03.2016
2016-00063 IS THERE LESS DISLOCATION RATE FOLLOWING DIRECT ANTERIOR APPROACH FOR TOTAL HIP ARTHROPLASTY ? personal data/biological material monocentric Christophe Tissot CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 15.02.2016
2016-00062 L’arresto cardiaco (AC) come trauma per il familiare: sintomatologia e possibili modelli di indagine, intervento e prevenzione non clinical, involving persons monocentric A Prof. Claudio Benvenuti Università degli Studi di Bergamo Fondazione Cuore Ticino, Breganzona
Comitato etico cantonale Ticino 21.07.2016
2016-00061 MK-3475-177: A Phase III Study of Pembrolizumab (MK-3475) vs. Chemotherapy in Microsatellite
Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal
Carcinoma (KEYNOTE-177)
clinical trial drugs phase 3 multicentric C Dr. med. Dieter Koeberle Merck Sharp & Dohme LLC, Global Clinical Trial Operations Switzerland St. Claraspital, Medizinische Onkologie, Basel
Hôpitaux Universitaires de Genève (HUG), Département d’Oncologie, Genf
Kantonsspital St. Gallen, Klinik für Onkologie und Hämatologie, St. Gallen
Univers More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) 28.04.2016
2016-00060 Dynamic Networks of Perception, Cognition and Action non clinical, involving persons monocentric A Ph.D, Gijs PLOMP University of Fribourg University of Fribourg, Fribourg
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 21.03.2016
2016-00059 Prävalenz einer Thrombozytopenie und Korrelation zum Schweregrad der sekundären Erythrozytose bei Erwachsenen mit angeborenen zyanotischen Herzfehlern. personal data/biological material monocentric DP Dr. med. Matthias Greutmann Klinik für Kardiologie, UniversitätsSpital Zürich, Zürich
Kantonale Ethikkommission Zürich 21.04.2016
2016-00058 The Medtronic CoreValve™ Evolut R™ FORWARD Study non clinical, involving persons multicentric A Prof. Dr. med. Francesco Maisano Medtronic (Schweiz) AG UniversitätsSpital Zürich, Zürich
Inselspital Bern, Bern
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern 17.11.2016
2016-00057 Gesundheitseffekte verschiedener städtischer Erholungsorte non clinical, involving persons monocentric A Dr. Nicole Bauer Eidg. Forschungsanstalt WSL WSL, Birmensdorf
Kantonale Ethikkommission Zürich 26.04.2016 Study has ended
2016-00056 Epidemiology of critical events, morbidity and mortality in neonatal anaesthesia:
A European prospective multicentre observational study
non clinical, involving persons multicentric A Prof Walid Habre European Society of Anaesthesiology Geneva University Hospitals, Geneva
SL Kinderanästhesie Universitätsklinik für Anästhesiologie und Schmerztherapie Inselspital, Bern
University Children's Hospital Basel , Basel
Kantonsspital Luzern, More ...
Commission Cantonale d'éthique de la recherche Genève (CCER) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... 31.03.2016 yes Study has ended
2016-00054 Comparison of perineal ultrasound in men before and after radical prostatectomy and in incontinent men after radical prostatectomy before and after operative treatment with male sling and comparison w More ... clinical trial medical devices monocentric A Prof. Dr. med. Hubert John Klinik für Urologie Klinik für Urologie, Kantonsspital Winterthur, Winterthur
Kantonale Ethikkommission Zürich 15.09.2016
2016-00053 A Phase 3, Placebo-Controlled, Randomized, Double-Blind, Multi-
Center Study of LJPC-501 in Patients with Catecholamine-Resistant Hypotension (CRH)
clinical trial drugs phase 3 monocentric C Dr Matthias Haenggi La Jolla Pharmaceutical Company Inc. Bern University Hospital - Inselspital, Bern
Kantonale Ethikkommission Bern 06.04.2016 Study has ended
2016-00052 A Randomized, Open-label Study of Ponatinib Versus Nilotinib in Patients with Chronic Myeloid Leukemia in Chronic Phase Following Resistance to Imatinib clinical trial drugs phase 3 monocentric C PD Dr. Dr. Stefan Balabanov ARIAD Pharmaceuticals, Inc. Universitätsspital Zürich, Klinik für Hämatologie, 8091 Zürich
Kantonale Ethikkommission Zürich 04.08.2016 Study has ended
2016-00051 A Swiss Paediatric Oncology Group (SPOG) initiated multi-center open-label randomized controlled multiple crossover non-inferiority trial on safety of a high versus low temperature limit defining feve More ... clinical trial other clinical trials multicentric B Prof. Dr. med Roland Ammann Swiss Paediatric Oncology Group SPOG Kinderklinik Inselspital, 3010 Bern
Hôpital Universitaire de Genève, Geneva
Centre Hospitalier Universitaire Vaudois CHUV, Lausanne
Universitäts-Kinderspital beider Basel UKBB, Hämatologie/Onkologie, More ...
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de l More ... 20.04.2016 yes Study has ended
2016-00050 Description, Predictors and Prediction Modeling of cART Medication Adherence and Immuno-virologic outcomes among HIV infected Adults in Lausanne, Switzerland personal data/biological material monocentric Susan Kamal Policlinique Medicale Universitaire Policlinique Medicale Universitaire, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 07.03.2016
2016-00048 CLXH254X2101 - A phase I dose finding study of oral LXH254 in adult patients with advanced solid tumors harboring MAPK pathway alterations clinical trial drugs phase 1 monocentric C Prof. Dr. med. Reinhard Dummer Novartis Pharma Schweiz AG Universitätsspital Zürich, Zürich
Kantonale Ethikkommission Zürich 31.03.2016 Study has ended
2016-00047 Testing the allergenicity of vaccinated vs. not vaccinated cats based on an in-vitro basophil activation test (BAT) using blood from cat allergic patients non clinical, involving persons monocentric A PD Dr. med. Thomas Kündig Department of Dermatology USZ USZ, 8091 Zurich
Kantonale Ethikkommission Zürich 10.03.2016 Study has ended
2016-00046 Real-time guided stereotactic radiotherapy in lung cancer using endovascular coils for tumor marking : head-to-head comparison between endovascular and bronchoscopic fiducial marker insertion. clinical trial other clinical trials monocentric B Dr. Duran Rafael CHUV University Hospital of Lausanne, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 12.07.2016