BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2020-00199 Clinical-pathological Case Series of 13 cases with PIK3CA-associated Overgrowth in Distal Extremities personal data/biological material monocentric PD Dr Peter Karl Bode Institut für Pathologie und Molekularpathologie, USZ, Zürich
Kantonale Ethikkommission Zürich 28.05.2020
2020-00198 5 years of patient specific instruments in knee arthroplasty: Preoperative planning versus postoperative radiological outcomes by using standard instrumentation PSI or single use instruments in over 7 More ... personal data/biological material monocentric PD Dr. med. Peter Koch Kantonsspital Winterthur, Winterthur
Kantonale Ethikkommission Zürich 10.03.2020
2020-00196 Clinical Impact of Enterovirus D68 personal data/biological material multicentric Prof. Adrian Egli University Hospital Basel University Hospital Basel, Basel
Universitäts-Kinderspital beider Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ 10.03.2020
2020-00195 Impact of T2Bacteria® rapid bloodstream infection diagnosis on antibiotic prescription and consumption: A single center before-after study personal data/biological material monocentric Dr Peter Keller Institute for Infectious Diseases, University of Bern Universität Bern, Institut für Infektionskrankheiten, Bern
Kantonale Ethikkommission Bern 24.03.2020 Study has ended
2020-00194 FLuid management in Intensive care unit patients receiving Renal Replacement Therapy personal data/biological material monocentric Dr. med. Luca Cioccari Klinik für Intensivmedizin Universitätsklinik für Intensivmedizin, Inselspital, Bern
Kantonale Ethikkommission Bern 02.03.2020 Study has ended
2020-00193 Electrical muscle stimulation for the treatment of functional posterior shoulder instability – A randomized multicentric study clinical trial medical devices monocentric A Prof. Dr. Markus Scheibel Charité University Hospital Berlin, Germany Schulthess Klinik, Zürich
Kantonale Ethikkommission Zürich 10.03.2020 yes Study has ended
2020-00192 Jodmonitoring 2020 - Swiss National Iodine Survey 2020 non clinical, involving persons multicentric A Dr. Isabelle Herter-Aeberli ETH Zurich ETH Zurich, Zurich
Ente Ospedaliero Cantonale, Lugano, Lugano
Kantonale Ethikkommission Zürich Comitato etico cantonale Ticino 30.11.2021 yes
2020-00191 Patient-specific in vitro models of ocular diseases personal data/biological material monocentric Prof. Dr. Botond Roska Institute of Molecular and Clinical Ophthalmology, Basel (IOB) Institute of Molecular and Clinical Ophthalmology Basel (IOB), Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 09.07.2020
2020-00190 Establishing a biobank to study ophthalmic diseases by collection and in vitro culture of patient specific cells and tissue of the eye non clinical, involving persons monocentric A Prof. Dr. Nicolas Feltgen Institute of Molecular and Clinical Ophthalmology Basel (IOB) Universitätsspital Basel, Augenklinik, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 15.06.2020 yes
2020-00189 HCT-HELP
Hematocrit adhoc self-testing in polycythemia vera patients
Proof of concept study
non clinical, involving persons multicentric A PD Dr med Alicia Rovo University Hospital of Bern University Hospital of Bern, Bern
Kantonsspital St.Gallen, Klinik für Medizinische Onkologie und Hämatologie, Rorschacher Strasse 95, CH-9007, St.Gallen
Kantonale Ethikkommission Bern Ethikkommission Ostschweiz (EKOS) 12.08.2020
2020-00188 Procalcitonin as a novel biomarker of liver function and predictor of early allograft dysfunction after liver transplantation - a retrospective singel-center study personal data/biological material monocentric Prof. Dr. med. Reto Schüpbach University Hosptial of Zurich University Hosptial of Zurich, Zurich
Kantonale Ethikkommission Zürich 04.03.2020
2020-00187 Early outcome and long-term results after complex endovascular intervention in aortic aneurysm with fenestrated and branched stent-grafts personal data/biological material monocentric PD Dr. med. Vladimir Makaloski Universitätsklinik für Herz- und Gefässchirurgie, Inselspital, Bern Universitätsklinik für Herz- und Gefässchirurgie, Inselspital, Bern, Bern
Kantonale Ethikkommission Bern 16.06.2020
2020-00186 A RANDOMIZED, DOUBLE-BLIND, DOUBLE-DUMMY, ACTIVE-CONTROLLED,
MULTICENTER, 2-PART PHASE II STUDY ON REPLACEMENT OF STEROIDS BY IFX-1 IN ACTIVE GRANULOMATOSIS WITH POLYANGIITIS (GPA) AND MICROSCOPIC PO More ...
clinical trial drugs phase 2 multicentric C Dr. Thomas Hauser InflaRx GmbH IZZ IMMUNOLOGIE-ZENTRUM ZÜRICH, Zürich
Kantonsspital St. Gallen, St. Gallen
Klinik Hirslanden Zürich, Zürich
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich 23.04.2020 Study has ended
2020-00185 Comparison of a visible and steerable sheet with a steerable but NON visible sheet in transseptal punction personal data/biological material monocentric PD Dr.med. Alexander Breitenstein Cardiology University Hospital Zurich, Zurich
Kantonale Ethikkommission Zürich 16.04.2020
2020-00184 Testing the new POLARx™ Cryoablation Catheter for pulmonary vein isolation in atrial fibrillation patients doing prior to the ablation and after a 3D reconstruction of the left atrium with a high-defi More ... personal data/biological material monocentric PD Dr.med. Alexander Breitenstein Cardiology Cardiology, University Hospital Zurich, Zurich
Kantonale Ethikkommission Zürich 30.04.2020
2020-00183 INDUCE-3 A Randomized, Double-blind, Adaptive, Phase II/III Study of GSK3359609 or Placebo in Combination with Pembrolizumab for First-Line Treatment of PD-L1 Positive Recurrent/Metastatic Head and N More ... clinical trial drugs phase 3 multicentric C Tomas Brezina GlaxoSmithKline GmbH & Co, KG Universitätsspital Zürich, CH-8091 Zürich
Klinik für Med. Onkologie und Hämatologie, Kantonsspital St. Gallen, CH-9007 St. Gallen
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS) 21.09.2021 Study has ended
2020-00182 HOVON 156 / AMLSG 28-18
A phase 3, multicenter, open-label, randomized, study of gilteritinib versus
midostaurin in combination with induction and consolidation therapy followed by one-year maintena More ...
clinical trial drugs phase 3 multicentric C Prof. Dr. med. Thomas Pabst HOVON Inselspital, Universitätsklinik für Medizinische Onkologie, Bern
Kantonsspital Aarau, Hämatologie und Transfusionsmedizin, Aarau
Luzerner Kantonsspital, Luzern
Universitätsspital Basel, Hämatologie, B More ...
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... 13.10.2020
2020-00181 Clinical outcome of loculated parapneumonic effusion managed surgically or by intrapleural fibrinolysis: a comparative multicenter study personal data/biological material multicentric Dr Jean Perentes CHUV - Chirurgie thoracique CHUV, Lausanne
Service de chirurgie thoracique et endocrinienne Hôpitaux Universitaires de Genève, Geneve
Hôpital Universitaire Lausanne (CHUV), Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER) 24.03.2020
2020-00180 A descriptive study of three spinal Units independently Managing obstructive Sleep apnoea personal data/biological material monocentric Dr. Med. Michael Baumberger Swiss Paraplegic Center Swiss Paraplegic Center, Nottwil
Ethikkommission Nordwest- und Zentralschweiz EKNZ 13.02.2020
2020-00179 Clinical feasibility of minimally supervised therapy after stroke with a hand rehabilitation robot (ReHapticKnob): pilot and main study clinical trial medical devices monocentric C2 Dr. med. Paolo Rossi Rehabilitation Engineering Laboratory, ETH Zurich Clinica Hildebrand Centro di riabilitazione Brissago, Brissago
Comitato etico cantonale Ticino 24.02.2020 Study has ended