| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2018-01163 | Analgesic efficacy of a combined saphenous nerve block and IPACK block versus local infiltration analgesia after anterior cruciate ligament reconstruction: a randomized controlled double-blinded trial | clinical trial | other clinical trials | monocentric | A | PD Dr. Eric Albrecht | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.08.2018 | Study has ended | ||||
| 2018-01162 |
Health Consequences of the Burden of Atrial Fibrillation - The Swiss-AF-BURDEN study |
non clinical, involving persons | multicentric | A | Prof. Dr. med. Michael Kühne | University Hospital Basel |
University Hospital Basel, Basel Universitätsspital-Inselspital Bern, Bern Luzerner Kantonsspital, Luzern Kantonsspital St Gallen, St Gallen EOC Ospedale Regionale di Lugano, Lugano Stadtspital Trieml More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 21.08.2018 | Study has ended | ||||
| 2018-01161 | Inhibition Training in older adults : A Biofeedback Study | clinical trial | other clinical trials | monocentric | A | Professeur Matthias Kliegel | Cigev- Université de Genève |
CIGEV Université de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 28.08.2018 | Study has ended | ||||
| 2018-01160 | A pharmacokinetic phase 1 study of anti-EGFR-immunoliosomes loaded with doxorubicin in patients with relapsed or refractory high-grade gliomas | clinical trial | drugs | phase 1 | multicentric | C | Dr. Heinz Läubli | Universitätsspital Basel |
Universitätsspital Basel, Klinik für Onkologie, Basel Kantonsspital Aarau, Medizinische Onkologie, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.09.2018 | Study has ended | ||
| 2018-01159 | 20290 SCOUT - A Phase 1/2 Study of the Oral TRK Inhibitor Larotrectinib in Pediatric Patients with Advanced Solid or Primary Central Nervous System Tumors | clinical trial | drugs | phase 1/2 | monocentric | C | Dr. med. Nicolas Gerber | Bayer Consumer Care AG |
Universitäts-Kinderspital, Zürich |
Kantonale Ethikkommission Zürich | 28.10.2021 | yes | |||
| 2018-01158 | Ex-vivo Gewebediagnostik durch Impedanzspektroskopie in der Neuro-Onkologie | personal data/biological material | monocentric | Prof. Dr. med. Andreas Raabe |
Universitätsklinik für Neurochirurgie, Inselspital, Bern |
Kantonale Ethikkommission Bern | 29.11.2018 | ||||||||
| 2018-01157 | Rôle des altérations du métabolisme dans la progression de la maladie rénale | non clinical, involving persons | monocentric | A | Prof Sophie de Seigneux | University hospital of geneva |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 18.09.2018 | ||||||
| 2018-01156 | Clinical outcome of patients with sacral chordomas treated with pencil beam scanning proton therapy at PSI | personal data/biological material | monocentric | Dr.med. Marc Walser | Center for Proton Therapy at Paul Scherrer Institute |
Center for Proton Therapy at Paul Scherrer Institute, Villigen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.06.2018 | Study has ended | ||||||
| 2018-01155 | Detect AB – Detecting Antibiotics - A pilot project | non clinical, involving persons | monocentric | A | PhD MD Jens Eckstein |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.08.2018 | Study has ended | ||||||
| 2018-01154 | MK-3475-716: Adjuvant Therapy with Pembrolizumab versus Placebo in Resected Highrisk Stage II Melanoma: A Randomized, Double-blind Phase 3 Study (KEYNOTE 716) | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Dr. sc. Egle Ramelyte | Merck Sharp & Dohme LLC |
UniverstitätsSpital Zürich, Zürich Inselspital Bern, Bern Universitätsspital Basel, Basel Hôpitaux Universitaires Genève (HUG), Genève HOCH Health Ostschweiz, Kantonsspital St. Gallen, St.Gallen Istit More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 06.09.2018 | |||
| 2018-01153 | Conservative and surgical treatment after triple finger flexor pulley rupture. | personal data/biological material | monocentric | Prof. Andreas Schweizer | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 11.07.2018 | Study has ended | ||||||
| 2018-01152 | Analysis of circulating tumor DNA as a prognostic biomarker in muscle invasive bladder cancer | personal data/biological material | monocentric | PD Dr. Roland Seiler | Inselspital Bern University Hospital |
Inselspital Bern University Hospital, Bern |
Kantonale Ethikkommission Bern | 10.08.2018 | |||||||
| 2018-01151 | The Use of Segmentation in Optic Coherence Tomography | personal data/biological material | monocentric | Prof. Dr. Dr. Mathias Abegg | Department of Ophthalmology, Inselspital |
Department of Ophthalmology, Bern University Hospital, Bern |
Kantonale Ethikkommission Bern | 16.10.2018 | |||||||
| 2018-01150 | Does the treatment of moderate to severe dysmenorrhea due to proven or suspected endometriosis in young adults with ZOELY ® or with VALETTE ® preserve bone mineral density? | clinical trial | drugs | phase 4 | monocentric | A | Guedj Noémie | Hopitaux Universitaires, Département de Gynécologie et Obstétrique |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.10.2018 | ||||
| 2018-01149 | Role of monocyte-derived dendritic cells (ModDCs) in kidney allograft dysfunction and rejection | non clinical, involving persons | monocentric | A | Carolina Obregon | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.09.2018 | ||||||
| 2018-01148 | Carotid artery endarterectomy with bifurcation advancement: insight in perioperative results. Are these results comparable with other carotid endarterectomie techniques? | personal data/biological material | monocentric | PD Dr. med. Zoran Rancic | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 20.07.2018 | |||||||
| 2018-01147 | Comparaison des méthodes de dosage des hormones stéroïdiennes pour l’évaluation clinique de jeunes filles présentant un hyperandrogénisme | personal data/biological material | monocentric | Dr. Michel Cauderay | Fondation USCADE |
Fondation USCADE, Pully |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.08.2018 | |||||||
| 2018-01146 |
An Open Label, Single Centre Pilot Study to Evaluate the Effect of KB195, a Novel Prebiotic Gluco-Oligosaccharide Mixture on Nitrogen Metabolism of the Gut in Patients with Urea Cycle Disorders St More ... |
clinical trial | other clinical trials | monocentric | A | Prof. Haeberle | Kaleido Biosciences, Inc. |
Kinderspital, Zürich |
Kantonale Ethikkommission Zürich | 30.10.2018 | yes | Study has ended | |||
| 2018-01145 | Molecular mechanisms of resistance to immunotherapy in cancer patients | personal data/biological material | monocentric | PD Dr. med Alessandra Curioni |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 30.07.2018 | ||||||||
| 2018-01143 | Using biomarkers to assess brain function in patients in a state of unresponsive wakefulness and minimal consciousness | non clinical, involving persons | monocentric | A | Dr. habil. Valentine L. MARCAR | REHAB Basel |
REHAB Basel, Basel Stadt |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.08.2018 | ||||||