| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-02250 | Risk factors for cardiac surgery - is surgery for failed percutaneous interventions the biggest of them all? | personal data/biological material | monocentric | PD Dr. med. David Reineke | Department of Cardiac Surgery |
Department of Cardiac Surgery, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 25.11.2025 | |||||||
| 2025-02249 | frAGILE: Effects of immobilization and retraining on muscle function in young and older adults | clinical trial | other clinical trials | monocentric | A | MSc Alberto Guzzi | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.11.2025 | |||||
| 2025-02240 | Cardiovascular diseaeses and psychiatric disorders in the general population: a prospective follow-up study (follow-up of PsyColaus) | non clinical, involving persons | monocentric | A | Prof. Pierre Marquet | CHUV - Psychiatrie |
Hôpital de Cery, CHUV, Prilly-Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.12.2025 | yes | |||||
| 2025-02239 |
Validity and reliability of the digitally adapted French version of the State Behavioral Scale (SBS) for assessing the level of sedation in non-communicative and ventilated children |
non clinical, involving persons | monocentric | A | Professor Anne-Sylvie Ramelet | CHUV, BPR |
IUFRS-CHUV, LAusanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.12.2025 | yes | |||||
| 2025-02238 |
Pelvic peritonectomy vs. Rectosigmoid resection in cytoreductive surgery for advanced epithelial ovarian cancer with pouch of douglas involvement |
personal data/biological material | monocentric | Dr. med. Tibor Zwimpfer | Universitätsspital Basel |
Universtitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.01.2026 | |||||||
| 2025-02235 | Comparative evaluation of 3D-HRCT-based functional imaging and SPECT-CT for preoperative prediction of postoperative outcomes following anatomical lung resection | personal data/biological material | monocentric | Dr. Aljaz Hojski | USB |
University Hospital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.11.2025 | |||||||
| 2025-02230 | Individualized Physiotherapy Addressing Patient-Specific Deficits in Amyotrophic Lateral Sclerosis Compared to Usual Care Physiotherapy: A Prospective, Pseudorandomized, Controlled, Interventional Stu More ... | clinical trial | other clinical trials | monocentric | A | Dr. Charlotte Vogt | ALS Clinic/Muskelzentrum |
ALS Clinic/Muskelzentrum , Kantonsspital St. Gallen, Sankt Gallen |
Ethikkommission Ostschweiz (EKOS) | 27.11.2025 | |||||
| 2025-02225 | Tiefenschätzung während endoskopischen neurochirurgischen Eingriffen mithilfe von Deep Learning | personal data/biological material | monocentric | Prof Dr. med. Carlo Serra | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 18.12.2025 | |||||||
| 2025-02221 | Implementationsstudie ACL-Prevention for All | non clinical, involving persons | monocentric | A | Dr. med. Natalie Mengis | KSBL (Verein Prevention for ALL) |
KSBL (Prevention for ALL), Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.12.2025 | yes | |||||
| 2025-02215 | post-Stroke Indications of DEpression and anxiety in Rehabilitation | personal data/biological material | monocentric | Tolga Dittrich, MD PhD | HOCH, Kantonsspital St. Gallen |
Department of Neurology, HOCH Cantonal Hospital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 06.11.2025 | |||||||
| 2025-02213 | Palliative Profile of older people at the emergency department: an analysis of problem importance in Europe | personal data/biological material | monocentric | Prof Sophie Pautex | Hospital University Geneva |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.12.2025 | |||||||
| 2025-02209 | Fertility and Pregnancy-related Outcomes in Autoimmune Rheumatic Diseases | personal data/biological material | monocentric | Dr. med. Jennifer Amsler | Inselspital Bern |
Universitätsklinik für Rheumatologie und Immunologie, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 11.12.2025 | |||||||
| 2025-02207 |
International real-world outcomes and treatment attrition with cabazitaxel and 177Lu-PSMA-617 in metastatic castration-resistant prostate cancer |
personal data/biological material | monocentric | Dr. med. Fabio Turco | Ankara University School of Medicine, Department of Medical Oncology, |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Comitato etico cantonale Ticino | 11.12.2025 | |||||||
| 2025-02200 | Expert Reader and automated evaluation of the central vein and rim lesion sign in inflammatory diseases of the central nervous system | personal data/biological material | monocentric | Dr. med. Frauke Kellner-Weldon | LUKS |
Kantonsspital Luzern, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.11.2025 | |||||||
| 2025-02198 | Unrestrained Lymphocytosis as a Predictor of Neurotoxicity Following Ciltacabtagene Autoleucel Therapy in Multiple Myeloma: A Real-World Single-Center Experience | personal data/biological material | monocentric | Prof. Dr. med. Thomas Pabst | Medical Oncology; Inselspital |
Medical Oncology; Inselspital, Bern |
Kantonale Ethikkommission Bern | 10.12.2025 | |||||||
| 2025-02197 | Plasma Oxytocin in Response to Oral Estradiol Valerate and Ethinylestradiol in Healthy Controls and Patients with AVP-Deficiency | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med Mirjam Christ-Crain | Universitätsspital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.12.2025 | |||||
| 2025-02196 | Evaluation de la réponse après une radiothérapie en fractionnement spatial (radiothérapie LATTICE). | personal data/biological material | monocentric | Rémy Kinj | CHUV - Radio-oncologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.12.2025 | |||||||
| 2025-02194 | Predictive value of OCT Inflammatory Biomarkers in DME using AI Analysis (OPTIMAL-3) | personal data/biological material | multicentric | PD Dr. med. Andreas Weinberger | AbbVie AG |
Pallas Klinik Olten, Olten Hospital Ophthalmic Jules-Gonin, Lausanne Stadtspital Zurich Triemli, Augenkinik, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 12.01.2026 | ||||||
| 2025-02193 | Effect of a change in dialysate glucose concentration in diabetic patients on dialysis | personal data/biological material | monocentric | Prof Olivier Bonny | HFR Fribourg – Hôpital cantonal |
HFR, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.11.2025 | |||||||
| 2025-02190 | Comparison of Lymphadenectomy of Robotic-Assisted versus Open Resection for Intrahepatic Cholangiocarcinoma (CLEAR—iCCA) – an international propensity score matched analysis | personal data/biological material | monocentric | PD Dr. med. Philip Müller | University Digestive Health Care Center |
Clarunis University Center for Gastrointestinal and Liver Diseases Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.12.2025 | |||||||