| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-00096 | OptiTherm: Un Regard Rétrospectif sur l'Hypothermie Peropératoire - Étude Comparative des Effets de l'Hypothermie Modérée vs Profonde dans la Reconstruction de l'Hypoplasie de l'Arc Aortique | personal data/biological material | monocentric | Dr. Tornike Sologashvili | Département chirurgie cardio-vasculaire |
Hôpitaux universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.03.2024 | |||||||
| 2024-00095 | Supporting people involuntarily admitted to a psychiatric hospital through a brief case management intervention that promotes personal recovery and reduces the negative effects of coercion: a pilot st More ... | clinical trial | other clinical trials | monocentric | A | Dr Stéphane Morandi | Centre Hospitalier Universitaire Vaudois, CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 15.03.2024 | |||||
| 2024-00093 | Sport-related concussions and their influence on on emotional state of mind (Masterthesis) | non clinical, involving persons | monocentric | A | PD Dr. med. Dominik Cordier | Unispital Basel (USB); Neurochirurgie |
Universitätsspital Basel, Neurochirurgie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.04.2024 | ||||||
| 2024-00092 | Calculation of Antibiotic Stewardship Indicators | personal data/biological material | monocentric | Prof. Dr. med. Sarah Tschudin Sutter | University Bern |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.02.2024 | |||||||
| 2024-00090 | Model-based strategy for 6-Mercaptopurine treatment in ALL maintenance phase : prediction of 6-TGN and 6-MMP concentrations and ANC to reduce toxicities. | personal data/biological material | monocentric | PD MD Dr. Francesco Ceppi | UNIL-CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 29.01.2024 | |||||||
| 2024-00089 | Open-Label Placebo for Non-Specific Pain in the Emergency Department: A Feasibility Study | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Roland Bingisser | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.03.2024 | |||||
| 2024-00087 | Investigating the impact of pressure relief performance on the occurrence of pressure injuries and shoulder pain: A prospective study in wheelchair users with spinal cord injury (PRperf) | non clinical, involving persons | monocentric | A | PhD Ursina Arnet | Swiss Paraplegic Research |
Schweizer Paraplegiker-Forschung, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.02.2024 | ||||||
| 2024-00086 | Processing and usage of human pediatric brain tissue, donated from deceased brain cancer patients, for research purpose | deceased persons | monocentric | Javad Nazarian | University Children's Hospital Zurich |
University Children's Hospital Zurich, Zürich |
Kantonale Ethikkommission Zürich | 29.10.2024 | |||||||
| 2024-00084 | Beat the Heat Studie | non clinical, involving persons | monocentric | A | Dr. Giulia Da Poian | SMS Lab, ETH Zurich |
SBB-Klimakammer, ETH Zürich, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.02.2024 | Study has ended | |||||
| 2024-00083 | SUNRAY-01, A Global Pivotal Study in Participants with KRAS G12C-Mutant, Locally Advanced or Metastatic Non-Small Cell Lung Cancer Comparing First- Line Treatment of LY3537982 and Pembrolizumab vs Pla More ... | clinical trial | drugs | phase 3 | multicentric | C | Laetitia Mauti | Eli Lilly and Company |
Kantonsspital Winterthur, Winterthur Hopital Universitaire de Lausanne CHUV, Lausanne Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.09.2024 | |||
| 2024-00082 | Analysis of the BAI program based on two points in time | personal data/biological material | monocentric | Prof Dr Diana Pacheco Barzallo | Universitätsklinik für Rheumatologie und Immunologie |
Universität Luzern, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.03.2024 | |||||||
| 2024-00081 | Epilepsy surgery in patients with tuberous sclerosis complex – a multicentre study of surgery outcome, predictors, and causes of epilepsy surgery failure | non clinical, involving persons | monocentric | A | Prof. Dr. med. Georgia Ramantani, PhD | UMC Utrecht |
Abteilung Neuropädiatrie, Universitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 19.04.2024 | yes | |||||
| 2024-00080 | Evaluation of the clinical results of Smooth Incision Lenticule Keratomileusis in patients with myopic astigmatism using the ELITA femtosecond laser. | personal data/biological material | monocentric | PD Dr. Theo Seiler | IROC |
IROC, Zürich |
Kantonale Ethikkommission Zürich | 19.04.2024 | |||||||
| 2024-00078 | Adherence to guideline recommendations during the COVID-19 pandemic: Retrospective analysis of clinical data | personal data/biological material | monocentric | Prof. Dr. med. Maria M. Wertli | Kantonsspital Baden |
Department of Internal Medicine, Kantonsspital Baden, 5404 Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.06.2024 | |||||||
| 2024-00076 | Genetic changes in E. coli Nissle during human colonization - further use of data and biomaterials of the Fat-study | personal data/biological material | monocentric | Prof. Dr. Wolf-Dietrich Hardt | Inselspital Bern |
Institute of Microbiology (D-BIOL), ETH Zurich, Zürich |
Kantonale Ethikkommission Zürich | 13.02.2024 | |||||||
| 2024-00075 | Treatment of patellofemoral osteoarthritis with nasal chondrocyte-based engineered cartilage implantation in a randomized, controlled, multi-center phase II clinical trial | clinical trial | transplant products | multicentric | C | PD Dr. Marcus Mumme | Universitätsspital Basel |
Universitätsspital Basel, Basel Inselspital, Bern Crossklinik, Basel Hôpitaux universitaires de Genève, Geneva Ospedale Regionale die Lugano, Lugano Sportclinic Zurich, Zurich Schulthess Klinik Zurich More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico canton More ... | 10.04.2024 | ||||
| 2024-00074 | Aortic Stenosis and Transthyretin Cardiac Amyloidosis: A Pragmatic, Streamlined International Registry | personal data/biological material | monocentric | Prof. Stefan Stortecky | Insel Gruppe AG |
Insel Gruppe AG, Bern |
Kantonale Ethikkommission Bern | 23.04.2024 | Study has ended | ||||||
| 2024-00072 | Neuropathic pain before, one year, five and ten years after Total Knee Arthroplasty: Exploring explanatory factors – Longitudinal follow-up. | personal data/biological material | monocentric | Dr Alice BONNEFOY-MAZURE | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.02.2024 | |||||||
| 2024-00071 | Postoperative outcomes following mastectomy with immediate breast implant placement: a retrospective study | personal data/biological material | monocentric | PD Dr Carlo M. Oranges, MD, PhD | HUG |
Geneva University Hospitals, Geneva University, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 30.01.2024 | |||||||
| 2024-00070 | Short-term effects of an SGLT2 inhibitor on divalent ions in autosomal dominant polycystic kidney disease | clinical trial | drugs | phase 4 | multicentric | B | Prof. Dr. Thomas Fehr |
Department of Internal Medicine Cantonal Hospital Graubuenden, Chur Division of Nephrology, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 12.03.2024 | ||||