| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-01687 | Untersuchung des Phänotyps, Krankheitsverlaufs und Therapieansprechen von Patienten mit Still Erkrankung | personal data/biological material | monocentric | PD Dr. med. Florian Kollert | Unispital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.09.2025 | |||||||
| 2025-01685 | Barriers to Mental Health Care for Socially Vulnerable Displaced Population with Depression in Basel-Stadt and Baselland: Pathways to Accessibility and Inclusion | non clinical, involving persons | monocentric | A | Dr Irene Falgas Bague | Swiss Tropical and Public Health Institute |
Swiss Tropical and Public Health Institute, Allschwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.09.2025 | ||||||
| 2025-01684 | Electrophysiological and Psychophysiological effects of Meditation | non clinical, involving persons | monocentric | A | Christoph Michel | All Here SA |
All Here SA, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 03.02.2026 | ||||||
| 2025-01683 | Second-Line Assessment in Geriatric Endocrine and Targeted Therapy for Metastatic Breast Cancer (mBC) - SAGE Study | personal data/biological material | monocentric | Dr. med. Elena Diana Chiru | Kantonsspital Baselland, Liestal |
Kantonsspital Baselland, Liestal, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.09.2025 | |||||||
| 2025-01682 |
CA244-0012 - IZABRIGHT-BLADDER01: A RANDOMIZED, OPEN-LABEL, PHASE 2/3 TRIAL OF IZALONTAMABBRENGITECAN VERSUS PLATINUM-BASED CHEMOTHERAPY FOR METASTATIC UROTHELIAL CANCER IN PARTICIPANTS WITH DISEA More ... |
clinical trial | drugs | phase 2 | multicentric | C | Professor Dr. med. Anja Lorch | Bristol-Myers Squibb Services Unlimited Company |
Universitätsspital Zürich Klinik für Medizinische Onkologie und Hämatologie, Zürich HOCH Health Ostschweiz Medizinische Onkologie und Hämatologie, St. Gallen Ospedale San Giovanni - IOSI, Bellinzona K More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 31.10.2025 | |||
| 2025-01681 | RAPTOR- Retrospective Analysis of PET-CT Tracking Outcomes in Recurrent Melanoma | personal data/biological material | monocentric | PD Dr. med. et phil. nat. Berna Özdemir | Universitätsklinik für Med. Onkologie Inselspital |
Universitätsklinik für Med. Onkologie, Bern |
Kantonale Ethikkommission Bern | 07.11.2025 | |||||||
| 2025-01680 | Parkinson in Switzerland – Prevalence, Risk-Factors, Care | personal data/biological material | monocentric | Prof. Dr. Stephan Bohlhalter | Institute of Pharmaceutical Medicine (ECPM) | University of Basel |
Luzerner Kantonsspital | Neurozentrum | Spitalstrasse, 6000 Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.09.2025 | |||||||
| 2025-01677 | CHIP-AML22: An open label complex clinical trial in newly diagnosed pediatric de novo AML patients – a study by the NOPHO-DB-SHIP consortium / Master Protocol | clinical trial | drugs | phase 3 | multicentric | B | Dr. med. Nastassja Scheidegger | Princess Máxima Center for Pediatric Oncology Utrecht, The Netherlands |
Universitäts-Kinderspital Zürich, Zürich Insel Gruppe AG Bern, Bern Children’s Hospital beider Basel (UKBB), Basel HUG - Hôpitaux Universitaires de Genève, Genève Ostschweizer Kinderspital St. Gallen, More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... | 31.10.2025 | yes | ||
| 2025-01676 | Precision ALS - Collection, Storage, Access, and Management of Prospective Data | personal data/biological material | monocentric | Dr. Charlotte Vogt | Trinity College Dublin |
ALS Clinic/Muskelzentrum , Kantonsspital St. Gallen, Sankt Gallen |
Ethikkommission Ostschweiz (EKOS) | 02.10.2025 | |||||||
| 2025-01675 | A retrospective evaluation of timing of risk-reducing surgeries and breast reconstruction in BRCA1/2 mutation carriers | personal data/biological material | monocentric | Prof. Dr. med. Jian Farhadi | Plastic Surgery Group AG |
Plastic Surgery Group AG, Zurich |
Kantonale Ethikkommission Zürich | 02.06.2026 | |||||||
| 2025-01674 | Prevalence and Clinical Implications of Specific ANCA Antibodies: A Retrospective Study at Lausanne University hospital | personal data/biological material | monocentric | Dr Denis Comte | CHUV - Médecine interne |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.11.2025 | |||||||
| 2025-01673 | Bern Endoscopy Stimulation Test (BEST) to determine hepatosplanchnic response to endoluminal fat stimulation in Metabolic dysfunction-associated fatty liver disease patients (BEST-HEPA) – A Pilot-Tria More ... | clinical trial | other clinical trials | monocentric | B | Prof. Dr. med. Reiner Wiest | Department of Gastroenterology, UVCM, Inselspital, Bern |
Department of Gastroenterology, UVCM, Inselspital, Bern, Bern |
Kantonale Ethikkommission Bern | 17.06.2026 | |||||
| 2025-01672 | Efficacy of the Latarjet Procedure for Anterior Shoulder Instability in Patients Over 50 years of age | non clinical, involving persons | monocentric | A | Dr. med. Philipp Kriechling | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 18.12.2025 | ||||||
| 2025-01671 | Inpatient vs. Outpatient Settings for Secondary Procedures Following Breast Reconstruction: A Retrospective Cohort Analysis | non clinical, involving persons | monocentric | A | Prof. Dr. med. Jian Farhadi | Affidea Plastic Surgery Group |
Affidea Plastic Surgery Group, Zurich |
Kantonale Ethikkommission Zürich | 18.12.2025 | ||||||
| 2025-01670 | Traumatisch eröffnete Bursa olecrani: Ergebnisse konservativer Therapie im Vergleich zur etablierten Bursektomie – eine retrospektive Analyse | personal data/biological material | monocentric | Dr. med. Tobias Rainer Köster | Bürgerspital Solothurn |
Bürgerspital Solothurn, Solothurn |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.10.2025 | |||||||
| 2025-01669 | Investigating the outcome of oligometastatic melanoma patients treated at the University Hospital Cancer Center Bern | personal data/biological material | monocentric | PD Dr. med. et. phil. Berna Özdemir | Inselspital, Universitätsspital Bern |
Inselspital, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 25.11.2025 | |||||||
| 2025-01668 | ASpiRE: A proof-of-mechanism and proof-of-concept clinical trial evaluating the safety, tolerability, biological and anti-tumour activity of Apalutamide with dual CXCR1 and CXCR2 blockade by SX-682 fo More ... | clinical trial | drugs | phase 1/2 | monocentric | C | PD Dr.ssa med. Ursula Vogl | The Institute of Cancer Research and Royal Marsden NHS Foundation Trust |
Istituto Oncologico della Svizzera Italiana, Ospedale San Giovanni, Bellinzona |
Comitato etico cantonale Ticino | 22.01.2026 | ||||
| 2025-01666 | SUBTOTAL PETROSECTOMY IN CHILDREN: WHAT CAN BE LEARNED FROM A MULTICENTER STUDY? | personal data/biological material | monocentric | Prof. Dr. med. T. Linder |
Klinik für Hals-, Nasen-, Ohren- und Gesichtschirurgie (HNO) - Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.08.2025 | ||||||||
| 2025-01665 |
Pilotstudie zur Anwendung des Da Vinci SP Systems zur Behandlung von Larynxkarzinomen 1. Subgruppe totale Laryngektomie 2. Subgruppe Teillaryngektomie |
personal data/biological material | monocentric | Prof. Dr. med. Gunesh Rajan |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.01.2026 | ||||||||
| 2025-01663 | Intrapulmonary Volume Changes During Synchronized Noninvasive Positive Pressure Ventilation In Preterm Infants | non clinical, involving persons | monocentric | A | PD Dr. med. Christoph Rüegger | University of Zurich |
University Hospital Zurich, Department of Neonatology, Zurich |
Kantonale Ethikkommission Zürich | 11.11.2025 | yes | |||||