| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-00586 | A Phase III, Randomized, Double-blind, Multicenter, Global Study of Rilvegostomig or Pembrolizumab Monotherapy for the First-line Treatment of Patients with PD-L1-high Metastatic Non-small Cell Lung C More ... | clinical trial | drugs | phase 3 | monocentric | C | Karim Abdelhamid | AstraZeneca AB |
University Hospital of Lausanne (CHUV), Medical Oncology, Oncology Department, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.08.2025 | ||||
| 2025-00584 | Effect of Phosphoric Acid Etching Duration on the Performance of Direct Resin-Based Composite Restorations in Permanent Anterior Teeth: A Randomized Controlled Single-Center Trial | clinical trial | other clinical trials | monocentric | A | PD Dr. med. dent. Florin Eggmann | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.04.2025 | |||||
| 2025-00582 | A Proof-of-Concept Study to Evaluate the precision of ABL-101 Perfluorocarbon and Fluorine-19 Magnetic Resonance Imaging in Mapping of Atherosclerotic Plaque Composition and Inflammation in Patients U More ... | clinical trial | drugs | phase 2 | monocentric | C | Professor Dr MD Patrik Michel | CHUV - Radiodiagnostic et |
Deputy Head of the Stroke Center, Neurology Service, Department of Clinical Neurosciences, CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.07.2025 | ||||
| 2025-00579 | VeMic: Association of microcirculation, Vexus score and femoral vein doppler in patients on the ICU after non-emergency cardiac surgery | non clinical, involving persons | monocentric | A | Dr. med. Gregor Loosen | University Hospital Basel |
University Hospital Basel, Intensive Care Unit, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.06.2025 | ||||||
| 2025-00578 | Observational study on hematological, and cardiopulmonary changes during a mountain ultramarathon. “CardiopulMUM” PROJECT | non clinical, involving persons | monocentric | A | Prof Grégoire Millet | UNIL - SSP - ISSUL |
Université de Lausanne, Le Bouveret (Valais) |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.07.2025 | ||||||
| 2025-00577 | Subjective Foot Value: A Simple, Valid, and Reliable Tool for Assessing Patient-Reported Foot Condition | personal data/biological material | monocentric | PD Dr. med. Stephan Wirth | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 10.06.2025 | |||||||
| 2025-00576 | Development of the ocular surface disease (OSD) specific item bank to measure quality of life parameters. | non clinical, involving persons | monocentric | A | Prof. Dr. Dr. Farhad Hafezi | UNSW Sydney, Australia |
ELZA Institute, Dietikon |
Kantonale Ethikkommission Zürich | 08.08.2025 | ||||||
| 2025-00575 | Retrospective chart review of patients aged 70 and older with oncologic diagnoses: Factors influencing hospitalization and emergency room visits | personal data/biological material | monocentric | PD Dr Marcus Vetter | Department of Oncology and Haematology |
Cantonal Hospital Baselland, Liestal, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.04.2025 | |||||||
| 2025-00574 | Herpes simplex Encephalitis: a Retrospective Observational Study | personal data/biological material | monocentric | Prof. Dr. med. Raoul Sutter | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.04.2025 | |||||||
| 2025-00573 | The use of SGLT-2 Inhibitors in diabetic kidney transplant patients: efficacy and safety (Masterarbeit) | personal data/biological material | monocentric | PD Dr. Patrizia Amico | Universitätsspital Basel |
Universitätsspital Basel, 4031 Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.08.2025 | |||||||
| 2025-00572 | The smartphone-based real-life activity data as a measure of functional impairment / functional performance in spine surgery | non clinical, involving persons | monocentric | A | Dr. med. Michal Ziga, FEBNS | Luzerner Kantonsspital |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.04.2025 | ||||||
| 2025-00571 | TRI0389 - Additional analysis of Acne vulgaris samples for identification of potential biomarkers and generation of evidence for new therapies | personal data/biological material | monocentric | Dr. Feriel Hacini-Rachinel | Novartis Pharma AG - Biomedical Research |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.04.2025 | |||||||
| 2025-00570 | Role of the blood-brain barrier in stress resilience: investigating new pathways towards pharmacological augmentation of stress resilience (a PHASR-PP project study) | clinical trial | other clinical trials | monocentric | B | Dr. med. Flurin Cathomas | University Medical Center of the Johannes Gutenberg University Mainz (UM) |
Psychiatric University Hospital, Zürich |
Kantonale Ethikkommission Zürich | 22.08.2025 | |||||
| 2025-00567 | Combining Low-keV Reconstruction and DLIR: Assessing Diagnostic Potential Across Clinical Tasks | personal data/biological material | monocentric | Marianna Gulizia | Centre Hospitalier Universitaire Vaudois |
Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.05.2025 | |||||||
| 2025-00566 | Identification of microbial antigens in brain tumors | personal data/biological material | monocentric | Pr Denis Migliorini | University of Geneva |
UNIGE, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 28.05.2025 | |||||||
| 2025-00565 | Tenofovir alafenamide in chronic hepatitis B: A multicenter real-life cohort study (REAL-TAF) | personal data/biological material | multicentric | Prof. Nasser Semmo | Inselspital |
Inselspital, Bern HOCH Health Ostschweiz, St. Gallen Epatocentro Ticino, Lugano Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 23.07.2025 | ||||||
| 2025-00564 | Study of human islet function and islet cell interconversion for targeted diabetes therapies | personal data/biological material | monocentric | Prof. Pedro Herrera | UNIGE |
UNIGE, Dept. Genetic Medicine & Development, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 27.11.2025 | |||||||
| 2025-00563 | Quality of Life and Care of Vestibular Schwannomas | non clinical, involving persons | monocentric | A | Prof. Dr. med. Alexander Huber | Universitätsklinikum Hamburg-Eppendorf |
University of Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.07.2025 | ||||||
| 2025-00562 | Analyzing brain tissue, extracranial tissues and bodily fluids in corpses – a resource characterizing the immunobiology of the central nervous system | deceased persons | monocentric | Prof. Dr. Marian C. Neidert | H-OCH Health Ostschweiz, Cantonal Hospital St. Gallen |
H-OCH Health Ostschweiz, Cantonal Hospital of St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 27.03.2025 | |||||||
| 2025-00561 |
Home care workers’ health risks of exposure to heat waves: Solutions for human adaptation to climate change in the context of working life extension |
clinical trial | other clinical trials | multicentric | A | Prof. Dr. Isabel Baumann |
Zurich University of Applied Sciences, Winterthur SUPSI, Mendrisio |
Kantonale Ethikkommission Zürich | Comitato etico cantonale Ticino | 06.06.2025 | |||||