BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2016-00135 CAIN457A2310- A randomized, double-blind, placebo- and active controlled multicenter trial to demonstrate efficacy of subcutaneous secukinumab compared to placebo and etanercept (in a single-blinded a More ... clinical trial drugs phase 3 multicentric C Dr. med. Lisa Weibel Novartis Pharma Schweiz AG Kinderspital Zürich – Eleonorenstiftung, Dermatologie, Steinwiesstrasse 75, 8032 Zürich
Kantonsspital St. Gallen, St. Gallen
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS) 09.05.2016 yes Study has ended
2016-00134 Prognostic value of Troponin T/I in infants with hypoplastic left heart syndrome between stage I and II personal data/biological material monocentric Dr. Anna Cavigelli-Brunner Kinderspital Zürich Kinderspital, Zürich
Kantonale Ethikkommission Zürich 10.03.2016
2016-00132 Study group on subarachnoid hemorrhage in Switzerland personal data/biological material multicentric David Bervini Universitätsklinik für Neurochirurgie Inselspital Bern, Bern
Inselspital Bern, Bern
Kantonsspital Aarau AG, Aarau
Universitätsspital Basel, Basel
Hopitaux Universitaire Geneve, Geneva
Kantonsspital St. Gallen, St. Gallen
Ospedale Regional More ...
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 01.03.2016
2016-00131 A phase III, multi-center, open-label trial to investigate the impact of a treat, counsel and cure strategy in men who have sex with men with hepatitis C infection in the Swiss HIV Cohort Study clinical trial drugs phase 3 multicentric C Dr. med. Dominique Braun Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich Division of infectious diseases and hospital epidemiology, Zurich
University Hospital Berne, Berne
University Hospital Basel, Basel
University Hospital Geneva, Geneva
Cantonal Hospital Sankt Gallen, S More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 17.06.2016 Study has ended
2016-00130 Associated Tooth Injuries with Jaw Fractures personal data/biological material monocentric Prof. Dr. med. Dr. med. dent. Martin Rücker Universität Zürich, Zürich
Kantonale Ethikkommission Zürich 12.04.2016
2016-00129 COMPLETE Trial - A randomized, comparative effectiveness study of complete versus culprit-only revascularization strategies to treat multi-vessel disease after primary percutaneous coronary interventi More ... clinical trial other clinical trials monocentric A PD Dr. Florim Cuculi Hamilton Health Sciences Corporation, Population Health Research Institute Luzerner Kantonsspital, Luzern
Ethikkommission Nordwest- und Zentralschweiz EKNZ 29.08.2016 Study has ended
2016-00128 Gray and white matter brain abnormalities in patients with Holmes tremor personal data/biological material monocentric PD Dr. med. Michael Schüpbach Universitätsklinik für Neurologie, Inselspital, Bern Universitätsklinik für Neurologie, Inselpital Bern, Bern
Kantonale Ethikkommission Bern 17.02.2016
2016-00127 SAKK 08/14 - IMPROVE
Investigation of metformin in patients with castration resistant prostate cancer in combination with enzalutamide vs. enzalutamide alone. A randomized, open label, phase II trial More ...
clinical trial drugs phase 2 multicentric C Dr. med. Christian Rothermundt SAKK Kantonsspital St. Gallen, St. Gallen
Kantonsspital Olten, Olten
Kantonsspital Baden, Baden
Luzerner Kantonsspital, Luzern
Universitätsspital Basel, Basel
Kantonsspital Aarau, Aarau
Bürgerspital Soloth More ...
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... 06.04.2016 Study has ended
2016-00126 Bioavailability of Medium Chain Triglycerides (MCTs) in Comatose Patients with Acute Brain Injury (ABI) clinical trial other clinical trials monocentric A Dr Mauro Oddo Nestec SA CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 23.03.2016 Study has ended
2016-00125 Quantitative assessment of mirror activity in the feet of patients with cerebral palsy non clinical, involving persons monocentric A Dr. Jacqueline Romkes Universitäts-Kinderspital beider Basel, Labor für Bewegungsuntersuchungen Universitäts-Kinderspital beider Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 21.03.2016 yes
2016-00124 Influence of vitamin D supplementation on the clot structure and markers of haemostasis and inflammation: a prospective cohort study non clinical, involving persons monocentric A Dr Marc Blondon & Dr Alessandro Casinis Geneva University Hospitals Division of Angiology & Haemostasis, Geneva University Hospitals and Faculty of Medicine, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 27.04.2016 Study has ended
2016-00123 Qualitätssicherungsstudie Herniamed non clinical, involving persons monocentric A Dr. med. Christian Helbling Herniamed GmbH Spital Linth, 8730 Uznach
Ethikkommission Ostschweiz (EKOS) 13.05.2016
2016-00121 Prostatic Artery Embolization Before Radical Prostatectomy in Prostate Cancer Patients: A Proof-of-concept Trial clinical trial medical devices multicentric A Dr. med. Dominik Abt Luzerner Kantonsspital Kantonsspital St. Gallen, St. Gallen
Kantonsspital Luzern, Luzern
Kantonsspital St. Gallen, ST. Gallen
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS) 27.01.2016
2016-00120 Multicenter prospective study of the STENTYS Xposition S for treatment of unprotected Left Main Coronary Artery Disease non clinical, involving persons multicentric A Dr. Daniel Weilenmann Stentys Kantonsspital St. Gallen, St. Gallen
Cardiocentro Ticino, Lugano
Ethikkommission Ostschweiz (EKOS) Comitato etico cantonale Ticino 05.04.2016 Study has ended
2016-00118 Factors influencing perioperative Outcomes and Survival after Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) - A retrospective analysis personal data/biological material monocentric Dr. med. Kuno Lehmann, PhD UniversitätsSpital Zürich , Zürich
Kantonale Ethikkommission Zürich 14.04.2016
2016-00117 Measuring changes in Quality of Life non clinical, involving persons monocentric A Prof. Dr. Marco Caversaccio MED-EL GmbH Universitätsklinik für HNO, Kopf- und Halschirurgie, Inselspital, Bern
Kantonale Ethikkommission Bern 05.07.2016 yes Study has ended
2016-00116 Safety and Efficacy of Interventional Treatment of Cardiac Arrhythmias – The Zurich Arrhythmia Intervention Registry personal data/biological material monocentric PD Dr. Thomas Wolber Universitätsspital Zürich UniversitätsSpital Zürich, Zürich
Kantonale Ethikkommission Zürich 12.04.2016
2016-00114 Is there a need for postoperative standardised radiographs after operative fixation of wrist- or ankle fractures? a prospective randomized single center single blinded trial clinical trial other clinical trials monocentric A Prof.Dr.med. Reto Babst LUKS Luzern, Luzern
Ethikkommission Nordwest- und Zentralschweiz EKNZ 25.04.2016
2016-00113 CQVM149B2302 - A multicenter, randomized, 52-week, double-blind, parallelgroup, active controlled study to compare the efficacy and safety of QVM149 with QMF149 in patients with asthma clinical trial drugs phase 3 multicentric C Prof. Dr. Dr. med. Martin Brutsche Novartis Pharma Schweiz AG Kantonsspital St. Gallen, St. Gallen
Kantonsspital Baselland, Liestal
Universitätsspital, Basel
Praxis, Gossau
Ospedale Regionale, Lugano
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Comitato etico cantonale Ticino 05.07.2016 Study has ended
2016-00111 A prospective study to evaluate the reduction of beam hardening CT artefacts using new iterative reconstruction algorithms. personal data/biological material monocentric Prof Xavier Montet Hôpitaux Universitaires de Genève Hôpitaux Universitaires Genève, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 13.04.2016