BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2021-00752 Usefulness of global coagulation assays to monitor treatment in patients with Hemophilia A (without or with inhibitors) treated with non-factor replacement therapy non clinical, involving persons monocentric A Prof. Dr. med Lorenzo Alberio CHUV - BH 18618 CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 03.06.2021 yes
2021-00751 Development and validation of a machine learning algorithm for prediction of outcome after lumbar spinal fusion for degenerative disease: The FUSE-ML Study personal data/biological material monocentric Prof. Dr. med. Mazda Farshad Universitätsklinik Balgrist Universitätsklinik Balgrist, Zürich
Kantonale Ethikkommission Zürich 20.04.2021 Study has ended
2021-00750 Reconsolidation and electroconvulsive therapy non clinical, involving persons monocentric A Dr. Else Schneider Universitäre Psychiatrischen Kliniken Basel Universitäre Psychiatrische Kliniken Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 15.06.2021
2021-00747 Früherkennung von Ovarialkarzinomen mittels Lavage des Cavum uteri und Duplex Sequencing - EHUD Studie

Early Detection of High Grade Ovarian Cancer Using Uterine
Lavage and Duplex Sequencing - EHU More ...
non clinical, involving persons monocentric A PD Dr. med. Christine Brambs Luzerner Kantonsspital, Frauenklinik Luzerner Kantonsspital, Frauenklinik, Lucerne
Ethikkommission Nordwest- und Zentralschweiz EKNZ 19.05.2021
2021-00746 A Prospective, Randomized, Double-Blind, Sham-Controlled, Multi-Center Pivotal Study to Evaluate the Efficacy and Safety of Duodenal Mucosal Resurfacing Using the Revita® System in Subjects with Type More ... clinical trial medical devices monocentric A2 Prof. Dr. Reiner Wiest Fractyl Laboratories Insel Gruppe AG, Bern
Kantonale Ethikkommission Bern 25.05.2021
2021-00745 Efficacy and safety comparison of brodalumab versus guselkumab in adult subjects with moderate-to-severe plaque psoriasis and inadequate response to ustekinumab. clinical trial drugs phase 3 multicentric C Dr. med. Julia-Tatjana Maul LEO Pharma GmbH University Zürich, Zürich
Kantonsspital St. Gallen, St. Gallen
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS) 13.07.2021
2021-00744 L’art de se déplacer pour une santé durable clinical trial other clinical trials monocentric A Prof. Anne-Violette Bruyneel Haute Ecole de Santé Genève Haute Ecole de Santé, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 10.05.2021
2021-00743 Expertenbericht über die Behandlung mit Yttrium-90-Radioembolisation (SIRT) bei hepatisch-dominanten soliden Tumoren an einem Comprehensive Cancer Center in der Schweiz personal data/biological material monocentric Dr.med. Alexander Siebenhüner Universitätsspital Zürich USZ, Zürich
Kantonale Ethikkommission Zürich 25.05.2021
2021-00742 The impact of the COVID-19 pandemic on cognition- a nested case-control study in adults and older adults from Ticino, southern Switzerland. non clinical, involving persons monocentric A Greta Rizzi Institute of Public Health Institute of Public Health - Università della Svizzera Italiana, Lugano
Comitato etico cantonale Ticino 07.06.2021
2021-00739 Cognitive profile in elderly epileptic patients treated with perampanel
as first add-on: a prospective, multicenter, observational study
non clinical, involving persons multicentric A Dr. Med. Caporro Matteo Neurocentro della Svizzera Italiana Neurocentro della Svizzera Italiana, Lugano
Inselspital, Bern University Hospital, Bern
Epilepsy Clinic Klinik Bethesda, Tschugg
Comitato etico cantonale Ticino Kantonale Ethikkommission Bern 20.05.2021
2021-00738 ENVAstTM Thrombectomy device as Adjunctive Reperfusion Modality in ST-segment Elevation Myocardial Infarction: (The NATURE Study) clinical trial medical devices multicentric A1 Prof. Marco Valgimigli Vesalio Co. Fondazione Cardiocentro Ticino, Lugano
University Hospital Inselspital of Bern, Bern
Lucerne Cantonal Hospital, Lucerne
Hôpitaux Universitaires de Genève (HUG), Genève
Comitato etico cantonale Ticino Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) 21.06.2021
2021-00737 Description de la prise en charge chirurgicale des patients avec variation du développement sexuel (VDS) au CHUV entre 1994 et 2021 personal data/biological material monocentric Dr Michael Hauschild CHUV - Pédiatrie CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 16.12.2021
2021-00736 20200234 - A Phase 2b Dose Ranging Study to Evaluate the Efficacy and Safety of Efavaleukin Alfa in Subjects with Active Systemic Lupus Erythematosus With Inadequate Response to Standard of Care Thera More ... clinical trial drugs phase 2 multicentric C Prof. Dr. med. Andrea Rubbert-Roth Amgen Inc. Kantonsspital St. Gallen, Rheumatologie, 9007 St. Gallen
Universitaetsspital Basel, Rheumatologie, 4031 Basel
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ 12.08.2021
2021-00735 Allergie et vaccination COVID-19 non clinical, involving persons monocentric A Dr. Yannick Muller CHUV - BH010-511 - IAL CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 14.04.2021
2021-00734 EFFECT OF CANNABINOIDS ON PAIN IN FABRY DISEASE PATIENTS; A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED, CROSSOVER, MULTICENTER STUDY. clinical trial drugs phase 2 multicentric B Dr. med. Albina Nowak University Hospital Zurich University Hospital Zürich, Zürich
Insel Hospital University of Bern, Bern
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern 24.08.2021
2021-00733 Video-Assisted ligation of intersphincteric Fistrula Tract for Anal Fistula: A Prospective Observational Study non clinical, involving persons monocentric A Prof Dr Med Dimitri Christoforidis EOC Dipartimento di Chirurgia EOC Dipartimento Chirurgia, Lugano
Comitato etico cantonale Ticino 04.05.2021
2021-00732 The Certain study: Combining Endo-cuff in a Randomized Trial for Artificial Intelligence Navigation clinical trial medical devices monocentric A1 Prof.Dr.Med.Dr.Phil Andrea De Gottardi Humanitas Research Hospital Servizio di Gastroenterologia Ente Ospedaliero Cantonale, Bellinzona
Comitato etico cantonale Ticino 04.05.2021
2021-00731 EVALUATION DE L’AIDE AU DIAGNOSTIC PAR BIOMARQUEURS SANGUINS CHEZ DES PATIENTS SOUFFRANT DE DEPRESSION, SUIVIS EN AMBULATOIRE non clinical, involving persons multicentric A Dr Aurélie Reymond-Delacrétaz Les Toises Psychiatry and Psychotherapy Center Les Toises-Psychiatry and Psychotherapy Center, Lausanne
Les Toises - Psychiatry and psychotherapy center, Sion; Yverdon-Les-Bains
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 21.07.2021
2021-00730 Trust, interprofessional collaboration and the role of the APN in the treatment pathway of women with gynaecological cancer – a mixed methods study non clinical, involving persons multicentric A Lotti Barandun Eastern Switzerland University of Applied Science Cantonal Hospital Lucerne, Lucerne
Hôpital du Valais, Sion
Ethikkommission Nordwest- und Zentralschweiz EKNZ Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 23.06.2021
2021-00729 Retrospective evaluation of analgesic procedures in minimally invasive esophagectomy (MIE) patients in a single tertiary high-caseload centre (REMIE). personal data/biological material monocentric Dr. Dominique Engel Bern University Hospital, Bern
Kantonale Ethikkommission Bern 06.05.2021