| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-00752 | Usefulness of global coagulation assays to monitor treatment in patients with Hemophilia A (without or with inhibitors) treated with non-factor replacement therapy | non clinical, involving persons | monocentric | A | Prof. Dr. med Lorenzo Alberio | CHUV - BH 18618 |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.06.2021 | yes | |||||
| 2021-00751 | Development and validation of a machine learning algorithm for prediction of outcome after lumbar spinal fusion for degenerative disease: The FUSE-ML Study | personal data/biological material | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 20.04.2021 | Study has ended | ||||||
| 2021-00750 | Reconsolidation and electroconvulsive therapy | non clinical, involving persons | monocentric | A | Dr. Else Schneider | Universitäre Psychiatrischen Kliniken Basel |
Universitäre Psychiatrische Kliniken Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.06.2021 | ||||||
| 2021-00747 |
Früherkennung von Ovarialkarzinomen mittels Lavage des Cavum uteri und Duplex Sequencing - EHUD Studie Early Detection of High Grade Ovarian Cancer Using Uterine Lavage and Duplex Sequencing - EHU More ... |
non clinical, involving persons | monocentric | A | PD Dr. med. Christine Brambs | Luzerner Kantonsspital, Frauenklinik |
Luzerner Kantonsspital, Frauenklinik, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.05.2021 | ||||||
| 2021-00746 | A Prospective, Randomized, Double-Blind, Sham-Controlled, Multi-Center Pivotal Study to Evaluate the Efficacy and Safety of Duodenal Mucosal Resurfacing Using the Revita® System in Subjects with Type More ... | clinical trial | medical devices | monocentric | A2 | Prof. Dr. Reiner Wiest | Fractyl Laboratories |
Insel Gruppe AG, Bern |
Kantonale Ethikkommission Bern | 25.05.2021 | |||||
| 2021-00745 | Efficacy and safety comparison of brodalumab versus guselkumab in adult subjects with moderate-to-severe plaque psoriasis and inadequate response to ustekinumab. | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Julia-Tatjana Maul | LEO Pharma GmbH |
University Zürich, Zürich Kantonsspital St. Gallen, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS) | 13.07.2021 | |||
| 2021-00744 | L’art de se déplacer pour une santé durable | clinical trial | other clinical trials | monocentric | A | Prof. Anne-Violette Bruyneel | Haute Ecole de Santé Genève |
Haute Ecole de Santé, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 10.05.2021 | |||||
| 2021-00743 | Expertenbericht über die Behandlung mit Yttrium-90-Radioembolisation (SIRT) bei hepatisch-dominanten soliden Tumoren an einem Comprehensive Cancer Center in der Schweiz | personal data/biological material | monocentric | Dr.med. Alexander Siebenhüner | Universitätsspital Zürich |
USZ, Zürich |
Kantonale Ethikkommission Zürich | 25.05.2021 | |||||||
| 2021-00742 | The impact of the COVID-19 pandemic on cognition- a nested case-control study in adults and older adults from Ticino, southern Switzerland. | non clinical, involving persons | monocentric | A | Greta Rizzi | Institute of Public Health |
Institute of Public Health - Università della Svizzera Italiana, Lugano |
Comitato etico cantonale Ticino | 07.06.2021 | ||||||
| 2021-00739 |
Cognitive profile in elderly epileptic patients treated with perampanel as first add-on: a prospective, multicenter, observational study |
non clinical, involving persons | multicentric | A | Dr. Med. Caporro Matteo | Neurocentro della Svizzera Italiana |
Neurocentro della Svizzera Italiana, Lugano Inselspital, Bern University Hospital, Bern Epilepsy Clinic Klinik Bethesda, Tschugg |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Bern | 20.05.2021 | |||||
| 2021-00738 | ENVAstTM Thrombectomy device as Adjunctive Reperfusion Modality in ST-segment Elevation Myocardial Infarction: (The NATURE Study) | clinical trial | medical devices | multicentric | A1 | Prof. Marco Valgimigli | Vesalio Co. |
Fondazione Cardiocentro Ticino, Lugano University Hospital Inselspital of Bern, Bern Lucerne Cantonal Hospital, Lucerne Hôpitaux Universitaires de Genève (HUG), Genève |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.06.2021 | ||||
| 2021-00737 | Description de la prise en charge chirurgicale des patients avec variation du développement sexuel (VDS) au CHUV entre 1994 et 2021 | personal data/biological material | monocentric | Dr Michael Hauschild | CHUV - Pédiatrie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.12.2021 | |||||||
| 2021-00736 | 20200234 - A Phase 2b Dose Ranging Study to Evaluate the Efficacy and Safety of Efavaleukin Alfa in Subjects with Active Systemic Lupus Erythematosus With Inadequate Response to Standard of Care Thera More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Andrea Rubbert-Roth | Amgen Inc. |
Kantonsspital St. Gallen, Rheumatologie, 9007 St. Gallen Universitaetsspital Basel, Rheumatologie, 4031 Basel |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.08.2021 | |||
| 2021-00735 | Allergie et vaccination COVID-19 | non clinical, involving persons | monocentric | A | Dr. Yannick Muller | CHUV - BH010-511 - IAL |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.04.2021 | ||||||
| 2021-00734 | EFFECT OF CANNABINOIDS ON PAIN IN FABRY DISEASE PATIENTS; A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED, CROSSOVER, MULTICENTER STUDY. | clinical trial | drugs | phase 2 | multicentric | B | Dr. med. Albina Nowak | University Hospital Zurich |
University Hospital Zürich, Zürich Insel Hospital University of Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 24.08.2021 | |||
| 2021-00733 | Video-Assisted ligation of intersphincteric Fistrula Tract for Anal Fistula: A Prospective Observational Study | non clinical, involving persons | monocentric | A | Prof Dr Med Dimitri Christoforidis | EOC Dipartimento di Chirurgia |
EOC Dipartimento Chirurgia, Lugano |
Comitato etico cantonale Ticino | 04.05.2021 | ||||||
| 2021-00732 | The Certain study: Combining Endo-cuff in a Randomized Trial for Artificial Intelligence Navigation | clinical trial | medical devices | monocentric | A1 | Prof.Dr.Med.Dr.Phil Andrea De Gottardi | Humanitas Research Hospital |
Servizio di Gastroenterologia Ente Ospedaliero Cantonale, Bellinzona |
Comitato etico cantonale Ticino | 04.05.2021 | |||||
| 2021-00731 | EVALUATION DE L’AIDE AU DIAGNOSTIC PAR BIOMARQUEURS SANGUINS CHEZ DES PATIENTS SOUFFRANT DE DEPRESSION, SUIVIS EN AMBULATOIRE | non clinical, involving persons | multicentric | A | Dr Aurélie Reymond-Delacrétaz | Les Toises Psychiatry and Psychotherapy Center |
Les Toises-Psychiatry and Psychotherapy Center, Lausanne Les Toises - Psychiatry and psychotherapy center, Sion; Yverdon-Les-Bains |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.07.2021 | |||||
| 2021-00730 | Trust, interprofessional collaboration and the role of the APN in the treatment pathway of women with gynaecological cancer – a mixed methods study | non clinical, involving persons | multicentric | A | Lotti Barandun | Eastern Switzerland University of Applied Science |
Cantonal Hospital Lucerne, Lucerne Hôpital du Valais, Sion |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.06.2021 | |||||
| 2021-00729 | Retrospective evaluation of analgesic procedures in minimally invasive esophagectomy (MIE) patients in a single tertiary high-caseload centre (REMIE). | personal data/biological material | monocentric | Dr. Dominique Engel |
Bern University Hospital, Bern |
Kantonale Ethikkommission Bern | 06.05.2021 | ||||||||