| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-00704 | PRE-MITRA - Prediction of reverse remodeling and outcome in patients with severe secondary mitral valve regurgitation undergoing transcatheter edge-to-edge mitral valve repair | non clinical, involving persons | multicentric | B | Prof. Christoph Gräni | Universitätsklinik Inselspital |
Insel gruppe AG Universitätspital, Bern Universitätspital Basel, Basel Fondazione Cardiocentro Ticino, Lugano Stadtspital Triemli, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 20.07.2021 | |||||
| 2021-00703 | Pharmakokinetik von Remdesivir und GS-441524 bei Patientinnen und Patienten mit einer schweren Niereninsuffizienz mit und ohne intermittierende Hämodialyse. | personal data/biological material | monocentric | PD Dr. med. Dominique Braun | Klinik für Infektionskrankheiten und Spitalhygiene Universitätsspital Zürich |
Klinik für Infektionskrankheiten und Spitalhygiene, Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 20.04.2021 | |||||||
| 2021-00702 | MO42541: A PHASE III, OPEN-LABEL, RANDOMIZED STUDY OF ATEZOLIZUMAB WITH LENVATINIB OR SORAFENIB VERSUS LENVATINIB OR SORAFENIB ALONE IN HEPATOCELLULAR CARCINOMA PREVIOUSLY TREATED WITH ATEZOLIZUMAB AN More ... | clinical trial | drugs | phase 3 | multicentric | C | PD Prof. Dr. med. Andreas Kremer | Roche Pharma (Schweiz) AG |
Universitätsspital Zürich, Zürich Inselspital Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 15.06.2021 | |||
| 2021-00701 | Swiss Atrial Fibrillation Cohort Study (Swiss-AF) | non clinical, involving persons | multicentric | A | Prof. Stefan Osswald | Universitätsspital Basel |
Universitätsspital Basel, Basel Inselspital Universitätsspital Bern, Bern Kardiologie, Kantonsspital Luzern, Luzern Kardiologie, Bürgerspital Solothurn, Solothurn Innere Medizin, Kantonsspital Baden, More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 22.04.2021 | |||||
| 2021-00700 | Analysis of the tumor microenvironment in tumors located in the colon and rectum | personal data/biological material | monocentric | Dr Thibaud Koessler | Université de Genève |
Geneva University Hospital, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.09.2021 | |||||||
| 2021-00699 | SURFACE - A prospective, non-interventional clinical study to evaluate the safety, performance, and clinical benefits of implants with TiUltra technology and associated prosthetic components. | non clinical, involving persons | multicentric | A | Dr Oliver Centrella | Nobel Biocare Services AG |
Centrella Zahnärzte, 8942 Oberrieden Dentalspecialist, 4622 Egerkingen Brunner Praxis für Zahnmedizin, Luzern Bodensee‐Implantat‐Zentrum AG, CH‐9400 Rorschach |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS) | 13.07.2021 | |||||
| 2021-00698 | Pilot study on cognitive and social function measures for early detection of progressive neurocognitive disorders in Switzerland | non clinical, involving persons | multicentric | A | Dr. Gianina Toller |
Kantonsspital St. Gallen, St. Gallen Memory Clinic, University of Geriatric Medicine Felix Platter, Basel Memory Clinic, Geriatrische Klinik St. Gallen, St. GAllen |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS) | 15.04.2021 | ||||||
| 2021-00697 | Development and optimization of in vivo magnetic resonance imaging parametric mapping | non clinical, involving persons | monocentric | A | Dr. / Ruud / van Heeswijk | CHUV - BH08.084 |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.05.2021 | ||||||
| 2021-00696 | Development of a checklist to assess barriers to hepatitis C virus (HCV) treatment (BACH-study, BArriers Checklist for Hepatitis C virus treatment) | non clinical, involving persons | monocentric | A | PD Dr. Isabelle Arnet | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.06.2021 | ||||||
| 2021-00695 | ComPAIN: Communication about PAIN in patients with headache | non clinical, involving persons | monocentric | A | Prof. Dr. me.d Susanne Wegener | University Hopsital Zurich and University of Zurich |
Klinik für Neurologie, USZ und UZH, Zürich |
Kantonale Ethikkommission Zürich | 01.06.2021 | ||||||
| 2021-00694 | Dépistage et évaluation du trouble de personnalité narcissique chez des patients consultant pour des difficultés de régulation des émotions | personal data/biological material | monocentric | Pr Nader Perroud | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 03.05.2021 | |||||||
| 2021-00693 | Stereotactic body radiotherapy in addition to standard of care treatment in patients with rare oligometastatic cancers (OligoRARE): a randomized, phase 3, open-label trial | clinical trial | other clinical trials | multicentric | B | Dr Matthias Guckenberger | European Organisation for Research and Treatment of Cancer |
UniversitaetsSpital Zurich, Zurich Inselspita, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 15.06.2021 | ||||
| 2021-00692 | Klinische Ergebnisse und Lebensqualität nach multimodaler Behandlung von arterio-venösen Malformationen | non clinical, involving persons | monocentric | A | Dr. med. Martin Takes | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.04.2022 | ||||||
| 2021-00691 | The Kaia COPD software Application: a digital therapeutic delivering PR to symptomatic COPD patients for self-management in the home setting – a randomized, controlled, multicentered and multinational More ... | clinical trial | medical devices | monocentric | A1 | PD Dr. med. Marc Spielmanns | KAIA Health Software GmbH |
Zürcher RehaZentren |Klinik Wald, Wald ZH |
Kantonale Ethikkommission Zürich | 04.05.2021 | |||||
| 2021-00690 | Fever Tracking: Konzeptstudie über die Durchführbarkeit von Fieberüberwachung mit mobilen Sensoren für zuhause | non clinical, involving persons | monocentric | A | Prof. Dr. Jens Eckstein | Universitätsspital Basel |
University Hospital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.09.2021 | ||||||
| 2021-00688 | CAAA617C12301 - PSMAddition : An International Prospective Open-label, Randomized, Phase III Study comparing 177Lu-PSMA-617 in combination with Standard of Care, versus Standard of Care alone, in adul More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Dominik Berthold | Novartis Pharma Schweiz AG |
CHUV, Lausanne Inselspital, Department of Medical Oncology, Bern Universitätsspital Zürich, Department für Onkologie und Hämatologie, Zürich |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 10.01.2022 | |||
| 2021-00687 | Development and validation of a tool for advising primiparous women during early labour (GebStart-Study) | clinical trial | other clinical trials | multicentric | A | Prof. Dr. Susanne Grylka | ZHAW Zürcher Hochschule für Angewandte Wissenschaften |
ZHAW Zürcher Hochschule für Angewandte Wissenschaften, Departement Gesundheit, Forschung Institut für Hebammen, Winterthur Universitätsspital Basel, Basel Kantonsspital Baden, Baden Luzerner Kantonssp More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 27.07.2021 | ||||
| 2021-00685 | Malformations lymphatiques chez l’enfant : prise en charge chirurgicale et radiologique | personal data/biological material | monocentric | PD Dr De Buys Roessingh | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 24.09.2021 | |||||||
| 2021-00684 | Effects of mandibular advancement devices (MAD) on night-time masticatory muscle activity (MAC): single center longitudinal observational pilot study (MAD-MAC) | non clinical, involving persons | monocentric | A | PD Dr. med. Dr. med. dent. Dominik A. Ettlin | UZH, ZZM |
Universität Zürich, Zentrum für Zahnmedizin, Zürich |
Kantonale Ethikkommission Zürich | 18.05.2021 | ||||||
| 2021-00683 | In vivo characterization of healthy skin in children ages 0 to 16 years with a novel, non-invasive imaging technique: line-field confocal optical coherence tomography. | non clinical, involving persons | monocentric | A | Stéphanie Christen-Zaech, PD | CHUV |
Département de Dermatologie et Pédiatrie Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.06.2021 | yes | |||||