| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-00193 | Outcomes after transjugular intrahepatic portosystemic shunt (TIPS) in a Swiss cohort | personal data/biological material | monocentric | Prof. Annalisa Berzigotti | UVCM Hepatology |
UVCM Hepatology, 3010 Bern |
Kantonale Ethikkommission Bern | 30.03.2023 | |||||||
| 2023-00192 | A prospective, double-blind, randomized, parallel group, placebo controlled, multicentre, Phase II study to investigate the efficacy, GPCR auto antibody neutralizing effect, safety, and tolerability o More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Lars C. Huber | Berlin Cures GmbH |
Stadtspital Zürich Standort Waid, Zürich Universitätsspital Basel, Basel |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.07.2023 | |||
| 2023-00191 | Temporal lobectomy series – Survival of patients with glioblastoma treated with temporal lobectomy compared to a historical cohort of patients treated with gross total resection | personal data/biological material | monocentric | Dr. med. Jenny Kienzler |
Klinik für Neurochirurgie, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.02.2023 | Study has ended | |||||||
| 2023-00189 |
Charakterisierung von HER2 low an primären Mammakarzinomen: Bestimmung HER-2 Status anhand von mRNA im Vergleich zu Immunhistochemie und FISH Analyse |
personal data/biological material | monocentric | Dr. med. Paula Klersy | Kantonsspital St. Gallen |
Kantonsspital, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 09.02.2023 | |||||||
| 2023-00188 | Seizure, cognitive, and functional outcomes of pediatric epilepsy surgery | personal data/biological material | monocentric | Prof. Dr. med. Georgia Ramantani | Universitäts-Kinderspital Zürich |
Universitäts-Kinderspital, Zürich |
Kantonale Ethikkommission Zürich | 04.04.2023 | |||||||
| 2023-00187 |
CA099-003:A Phase 1/2 Study of BMS-986408 Alone and in Combination with Nivolumab or with Nivolumab and Ipilimumab in Participants with Advanced Solid Tumors |
clinical trial | drugs | phase 1/2 | multicentric | C | Prof. Dr. med. Markus Jörger | Bristol-Myers Squibb International Corporation |
Kantonsspital St. Gallen, St. Gallen University Hospital Basel, Medical Oncology, Basel University Hospital Geneva, Geneva |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER) | 10.05.2023 | |||
| 2023-00186 | Functional profiling of CD4 T cells in human cancer for optimized cancer immunotherapy | personal data/biological material | monocentric | Camilla Jandus |
University of Geneva, 1211 Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 03.04.2023 | ||||||||
| 2023-00185 | Life of lesions in ANCA-associated glomerulonephritis | personal data/biological material | monocentric | PD Dr Helmut Hopfer | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.04.2023 | |||||||
| 2023-00184 | Analysis of sexual health of patients with low grade glioma treated with pencil beam scanning proton therapy | non clinical, involving persons | monocentric | A | Prof.Dr.med. Damien C. Weber | Center for Protontherapy at Paul Scherrer Institut |
Center for Protontherapy at Paul Scherrer Institut, Villigen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.03.2023 | Study has ended | |||||
| 2023-00182 | Comparison of two perioperative analgesia strategies: epidural catheters vs. intravenous methadone | personal data/biological material | monocentric | Prof. Dr. med. Donat R. Spahn | Institut für Anästhesiologie |
Institut für Anästhesiologie - USZ, Zürich |
Kantonale Ethikkommission Zürich | 21.03.2023 | |||||||
| 2023-00181 | Erfassung der körperlichen Leistungsfähigkeit bei prä-pubertären Kindern und Erwachsenen | non clinical, involving persons | monocentric | A | Dr. Ralf Roth | Universität Basel |
Universität Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.03.2023 | yes | |||||
| 2023-00180 | Fat fractions of the rotator cuff muscles acquired with two-point Dixon MR imaging predicting outcome after arthroscopic rotator cuff repair | personal data/biological material | monocentric | Prof. Dr. med. Reto Sutter | University Hospital Balgrist |
University Hospital Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 07.03.2023 | |||||||
| 2023-00179 | Neural correlates of willful ignorance decisions – an observational fMRI study | non clinical, involving persons | monocentric | A | Dr Thomas Baumgartner | University of Bern |
University of Bern, Bern |
Kantonale Ethikkommission Bern | 05.05.2023 | ||||||
| 2023-00178 | Feasibility and safety of an individualised, symptom-titrated acute aerobic and resistance exercise session in patients with post-COVID-19 syndrome - a pilot study (bachelor’s thesis) | non clinical, involving persons | monocentric | A | Fabian Schwendinger | University of Basel |
Department of Sport, Exercise and Health, University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.03.2023 | ||||||
| 2023-00176 | The impact of exercise on cognitive performance and subjective feeling of fatigue | non clinical, involving persons | monocentric | A | Prof Nicolas Place | ISSUL |
Université de Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.05.2023 | ||||||
| 2023-00175 | Evaluation of Safety and Tolerability of Salvia haenkei extract as a Dietary Supplement Ingredient in a Healthy Population: A Randomized, Open label, Parallel-arm, Two-dose Study | clinical trial | other clinical trials | monocentric | B | Dr. Roberta Noseda | IBSA Farmaceutici Italia Srl |
Istituto di Scienze Farmacologiche della Svizzera Italiana, Lugano |
Comitato etico cantonale Ticino | 13.04.2023 | |||||
| 2023-00174 |
A Phase 1/2 open-label study of Debio 0123 in combination with temozolomide in adult participants with recurrent or progressive glioblastoma and of Debio 0123 in combination with temozolomide and r More ... |
clinical trial | drugs | phase 1/2 | monocentric | C | Prof. Dr. med. Patrick Roth | Debiopharm International S.A. |
Department of Neurology, University Hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 28.03.2023 | Study has ended | |||
| 2023-00173 | IMPACT: Increasing mental health and psychological well-being in patients and healthy adults through nonexercise activity | clinical trial | other clinical trials | monocentric | A | Prof. Dr. Claudio R. Nigg | Universität Bern |
Institut für Sportwissenschaft, Universität Bern, Bern |
Kantonale Ethikkommission Bern | 21.04.2023 | |||||
| 2023-00172 |
AN OPEN-LABEL, 2-ARM, MULTICENTER, RANDOMIZED PHASE 3 STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ELRANATAMAB (PF-06863135) + DARATUMUMAB + LENALIDOMIDE VERSUS DARATUMUMAB + LENALIDOMIDE + DEXAMET More ... |
clinical trial | drugs | phase 3 | multicentric | C | PD Dr. Jereon Goede | Pfizer Inc |
Kantonspital Winterthur, Winterthur Inselspital Bern, Bern Kantonspital Aarau, Aarau Département d'oncologie UNIL-CHUV, Lausanne Kantonspital Graubünden, Graubünden Clinic for Hematology & Oncology Hi More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.06.2023 | |||
| 2023-00171 | ONC201 for the Treatment of Newly Diagnosed H3 K27M-mutant Diffuse Glioma Following Completion of Radiotherapy: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study | clinical trial | drugs | phase 3 | multicentric | C | Dr Emilie Le Rhun | Chimerix, Inc. |
University Hospital Zurich, Zurich Lausanne University Hospital Center (CHUV), Lausanne |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.06.2023 | |||