| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-02153 | Appropriateness of in-hospital intravenous iron therapy in a Swiss tertiary care hospital – a quality control study | personal data/biological material | monocentric | PD Dr. med. Michael Osthoff | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.11.2021 | |||||||
| 2021-02025 | Recombinant human C1 esterase inhibitor (conestat alfa) in the prevention of acute ischemic cerebral and renal events after transcatheter aortic valve implantation: a multi-center, randomized, double- More ... | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. med. Michael Osthoff | Innere Medizin |
University Hospital Basel, Basel Stadtspital Triemli, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 30.11.2021 | |||
| 2021-01338 | Occurrence of antibodies cross-reacting with autoantigens in primary EBV infection – a longitudinal, observational study | non clinical, involving persons | monocentric | A | PD Dr. med. Michael Osthoff | University Hospital Basel, Division of Internal Medicine |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.08.2021 | ||||||
| 2021-00201 | Evaluation of the FilmArray meningitis/encephalitis panel at the University Hospital Basel: a retrospective study | personal data/biological material | monocentric | PD Dr. med. Michael Osthoff |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.02.2021 | ||||||||
| 2020-02738 | Appropriateness of blood culture collection at the University Hospital Basel: a quality control study | personal data/biological material | monocentric | PD Dr. med. Michael Osthoff |
Innere Medizin Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.12.2020 | ||||||||
| 2020-01252 | Recombinant human C1 esterase inhibitor (conestat alfa) in the prevention of severe SARS-CoV-2 infection in hospitalized patients with COVID-19: a randomized, parallel-group, open-label, multi-center More ... | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. med. Michael Osthoff | University Hospital Basel |
University Hospital Basel, Basel Kantonsspital St. Gallen, St. Gallen Klinik für Innere Medizin, Stadtspital Triemli Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 07.07.2020 | Study has ended | ||
| 2020-01013 | Compassionate use of recombinant human C1 esterase inhibitor (Conestat alfa) in the prevention of clinical deterioration in high-risk subjects with COVID-19 pneumonia: a case series and matched case-c More ... | personal data/biological material | monocentric | PD Dr. med. Michael Osthoff | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.05.2020 | |||||||
| 2019-02229 | Probability of target attainment with standard intermittent bolus administration of cefazolin in patients with complicated infections caused by Staphylococcus aureus: A prospective single-center cohor More ... | non clinical, involving persons | monocentric | A | PD Dr. med. Michael Osthoff | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.12.2019 | Study has ended | |||||
| 2019-01716 | Conestat alfa ( a recombinant human C1 esterase inhibitor) for the prevention of acute kidney injury after non - ST elevation myocardial infarction: a randomized, double-blind, placebo control, multi More ... | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. med. Michael Osthoff | Pharming Technologies B.V. |
University Hospital Basel, Basel Inselspital Bern, Bern Hôpitaux Unversitaires Geneve (HUG), Genève Fondazione Cardiocentro Ticino, Lugano |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 28.10.2019 | Study has ended | ||
| 2019-00185 | Evaluation of the Duration of Antimicrobial Treatments in Common Infectious Diseases at Three Swiss Tertiary Care Hospitals – a Quality Control Study | personal data/biological material | multicentric | PD Dr. med. Michael Osthoff | Universitätsspital Basel |
Universitätsspital Basel, Basel Kantonsspital Aarau, Aarau Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS) | 06.02.2019 | ||||||
| 2019-00012 | Recombinant human C1 esterase inhibitor (Conestat alfa) in the prevention of contrast-induced nephropathy in high-risk subjects (PROTECT): a randomized, placebo-controlled, double-blind single-center More ... | personal data/biological material | monocentric | PD Dr. med. Michael Osthoff | Universitätsspital Basel, Klinik Innere Medizin |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.01.2019 | |||||||
| 2017-02072 | Probability of target attainment with standard intermittent bolus administration of β-lactam antibiotics in patients with bloodstream infections caused by Staphylococcus aureus and aerobic Gram-negati More ... | non clinical, involving persons | monocentric | A | PD Dr. med. Michael Osthoff | Universitätsspital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.12.2017 | Study has ended | |||||
| 2017-00539 | Comprehensive analysis of the Outpatient Parenteral Antibiotic Therapy (OPAT) program at the University Hospital Basel during 2015-2016 | personal data/biological material | monocentric | PD Dr. med. Michael Osthoff |
Universitätsspital Basel, Klinik Innere Medizin, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.05.2017 | ||||||||