Type of clinical trial
Category
Study Ended
Study phase (clinical trials only)
multi- / monocentric
BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2023-01879 Incidence of acute kidney injury in patients treated with beta-lactam monotherapy or beta-lactam/amikacin combination therapy after autologous hematopoietic stem cell transplantation: a two-center ret More ... personal data/biological material multicentric Prof Dr. med. Michael Osthoff Universitätsspital Basel, Basel
Inselspital Bern, Bern
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern 09.11.2023
2022-01708 Can continuous infusion coupled with therapeutic drug monitoring optimize flucloxacillin and cefazolin target attainment compared to standard intermittent bolus dosing in patients with complicated Sta More ... clinical trial drugs phase 2 monocentric A Prof. Dr. med. Michael Osthoff University Hospital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 29.11.2022
2022-01218 Probability of optimal target attainment of amikacin in patients treated for a hematological disorder: A prospective, single-center study and PKPD-analysis non clinical, involving persons monocentric A Prof Dr. Michael Osthoff Universitätsspital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 23.08.2022 Study has ended
2021-02409 Leptospirosis, Tularemia and Hepatitis E in a Rural Mountain Valley in the Alpine Region of Switzerland – A Cross-Sectional Exploratory Seroprevalence Study non clinical, involving persons multicentric A PD Dr. med. Michael Osthoff University Hospital Basel University Hospital Basel, Basel
Center da sandà Val Müstair, 7536 Sta. Maria VM
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Zürich 03.03.2022
2021-02153 Appropriateness of in-hospital intravenous iron therapy in a Swiss tertiary care hospital – a quality control study personal data/biological material monocentric PD Dr. med. Michael Osthoff Universitätsspital Basel Universitätsspital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 18.11.2021
2021-02025 Recombinant human C1 esterase inhibitor (conestat alfa) in the prevention of acute ischemic cerebral and renal events after transcatheter aortic valve implantation: a multi-center, randomized, double- More ... clinical trial drugs phase 2 multicentric C PD Dr. med. Michael Osthoff Innere Medizin University Hospital Basel, Basel
Stadtspital Triemli, Zürich
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Zürich 30.11.2021
2021-01338 Occurrence of antibodies cross-reacting with autoantigens in primary EBV infection – a longitudinal, observational study non clinical, involving persons monocentric A PD Dr. med. Michael Osthoff University Hospital Basel, Division of Internal Medicine University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 17.08.2021
2021-00379 Probability of early target attainment with continuously administered piperacillin/tazobactam and meropenem in critically ill patients: A retrospective cohort study from 2017 to 2021 personal data/biological material monocentric PD Dr. Michael Osthoff University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 24.02.2021
2021-00201 Evaluation of the FilmArray meningitis/encephalitis panel at the University Hospital Basel: a retrospective study personal data/biological material monocentric PD Dr. med. Michael Osthoff University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 03.02.2021
2020-02738 Appropriateness of blood culture collection at the University Hospital Basel: a quality control study personal data/biological material monocentric PD Dr. med. Michael Osthoff Innere Medizin Universitätsspital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 02.12.2020
2020-02260 A novel rapid, mobile, lab-independent and sensitive SARS-CoV-2 test at the point-of-need, to break the chain of infection non clinical, involving persons monocentric A PD Dr. Michael Osthoff University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 16.04.2021 Study has ended
2020-01369 Invasive pneumococcal disease as the initial presentation of multiple myeloma, smol-dering myeloma or MGUS: identification of predictors for an earlier diagnosis personal data/biological material multicentric PD. Dr. med. Michael Osthoff Universitätsspital Basel Universitätsspital Basel, Basel
St. Claraspital, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ 02.07.2020
2020-01252 Recombinant human C1 esterase inhibitor (conestat alfa) in the prevention of severe SARS-CoV-2 infection in hospitalized patients with COVID-19: a randomized, parallel-group, open-label, multi-center More ... clinical trial drugs phase 2 multicentric C PD Dr. med. Michael Osthoff University Hospital Basel University Hospital Basel, Basel
Kantonsspital St. Gallen, St. Gallen
Klinik für Innere Medizin, Stadtspital Triemli Zürich, Zürich
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich 07.07.2020 Study has ended
2020-01013 Compassionate use of recombinant human C1 esterase inhibitor (Conestat alfa) in the prevention of clinical deterioration in high-risk subjects with COVID-19 pneumonia: a case series and matched case-c More ... personal data/biological material monocentric PD Dr. med. Michael Osthoff University Hospital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 04.05.2020
2019-02229 Probability of target attainment with standard intermittent bolus administration of cefazolin in patients with complicated infections caused by Staphylococcus aureus: A prospective single-center cohor More ... non clinical, involving persons monocentric A PD Dr. med. Michael Osthoff University Hospital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 20.12.2019 Study has ended
2019-01716 Conestat alfa ( a recombinant human C1 esterase inhibitor) for the prevention of acute kidney injury after non - ST elevation myocardial infarction: a randomized, double-blind, placebo control, multi More ... clinical trial drugs phase 2 multicentric C PD Dr. med. Michael Osthoff Pharming Technologies B.V. University Hospital Basel, Basel
Inselspital Bern, Bern
Hôpitaux Unversitaires Geneve (HUG), Genève
Fondazione Cardiocentro Ticino, Lugano
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino 28.10.2019 Study has ended
2019-00185 Evaluation of the Duration of Antimicrobial Treatments in Common Infectious Diseases at Three Swiss Tertiary Care Hospitals – a Quality Control Study personal data/biological material multicentric PD Dr. med. Michael Osthoff Universitätsspital Basel Universitätsspital Basel, Basel
Kantonsspital Aarau, Aarau
Kantonsspital St. Gallen, St. Gallen
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS) 06.02.2019
2019-00012 Recombinant human C1 esterase inhibitor (Conestat alfa) in the prevention of contrast-induced nephropathy in high-risk subjects (PROTECT): a randomized, placebo-controlled, double-blind single-center More ... personal data/biological material monocentric PD Dr. med. Michael Osthoff Universitätsspital Basel, Klinik Innere Medizin Universitätsspital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 11.01.2019
2017-02072 Probability of target attainment with standard intermittent bolus administration of β-lactam antibiotics in patients with bloodstream infections caused by Staphylococcus aureus and aerobic Gram-negati More ... non clinical, involving persons monocentric A PD Dr. med. Michael Osthoff Universitätsspital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 21.12.2017 Study has ended
2017-00539 Comprehensive analysis of the Outpatient Parenteral Antibiotic Therapy (OPAT) program at the University Hospital Basel during 2015-2016 personal data/biological material monocentric PD Dr. med. Michael Osthoff Universitätsspital Basel, Klinik Innere Medizin, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 09.05.2017