BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2024-D0037 The DEXTER-assisted non-acute cholecystectomy Study clinical trial medical devices multicentric A1 Prof. Dr. med. Stefan Breitenstein Distalmotion SA Kantonsspital Winterthur, Winterthur
Hirslanden Zurich, Chirurgisches Zentrum Zürich
Witellikerstrasse 40
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 14.06.2024
2024-00871 Feasibility of treadmill exercise echocardiography to identify exercise induced pulmonary hypertension in everyday practice personal data/biological material monocentric Prof. Dr. med. Christine Attenhofer Jost HerzGefässZentrum im Park, Klinik Im Park, Hirslanden HerzGefässZentrum Im Park, Klinik im Park, Hirslanden, Zürich
Kantonale Ethikkommission Zürich 18.06.2024
2023-D0107 A Non-Randomized, Prospective or Retrospective, Open-Label, Multi-Center, Observational Clinical Study with Two Arms to Further Evaluate Safety and Performance of the NEXUS® Aortic Arch Stent Graft Sy More ... clinical trial medical devices monocentric A1 Prof. Dr. med. Mario Lachat Endospan ltd Hirslanden Klinik, Zürich
Kantonale Ethikkommission Zürich 12.12.2023
2023-D0097 CAMBRIA-2 (ClinO-MD)
A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next-Generation, Oral Selective Estrogen Receptor Degrader) Versus Standar More ...
clinical trial in vitro diagnostic medical devices multicentric C2 Dr. med. Ursina Zürrer-Härdi AstraZeneca AB Kantonsspital Winterthur, Klinik für Medizinische Onkologie und Hämatologie, Winterthur
Kantonsspital Baden, Im Ergel
Hirslandenklinik St. Anna, Zentrum für Onkologie
St. Anna-Strasse 32
Universitäts More ...
Kantonale Ethikkommission Zürich Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, More ... 28.03.2024
2023-D0092 Mid- oder high-flex Stäbe versus low-flex Stäbe von SpineShape System IV zur Behandlung der degenerativen Lendenwirbelsäule - eine prospektive, multizentrische, randomisiert kontrollierte Non-Inferior More ... clinical trial medical devices multicentric C3 Dr. med. Philipp Cathrein SpineSave AG Hirslanden Klinik Linde, Biel
Spital Aarberg, Aarberg
Kantonale Ethikkommission Bern Kantonale Ethikkommission Bern 27.02.2024
2023-D0042 CT-Guided Interventions using a patient mounted navigation system: Initial Clinical Experience clinical trial medical devices monocentric A1 Dr. Med. Sebastian Kos Universitätsspital Basel Klinik Hirslanden St. Anna, Lucerne
Ethikkommission Nordwest- und Zentralschweiz EKNZ 11.07.2023
2023-02200 GO44145 - A PHASE III, MULTICENTER, RANDOMIZED, OPEN‑LABEL STUDY COMPARING THE EFFICACY AND SAFETY OF GLOFITAMAB (RO7082859) IN COMBINATION WITH POLATUZUMAB VEDOTIN PLUS RITUXIMAB, CYCLOPHOSPHAMIDE, D More ... clinical trial drugs phase 3 multicentric C Prof. Dr. med. Frank Stenner Roche Pharma (Schweiz) AG Universitätsspital Basel, Basel
Hirslanden - Klinik im Park; OnkoZentrum Zürich, Zürich
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Zürich 24.04.2024
2023-02168 Implantation of Allogenic Cartilage Mini-grafts: First-In-Human Study for Treating Chondral Lesions of the Knee. Open Cohort, Small Sample Size with 6 months Follow-Up clinical trial transplant products multicentric C Dr Marco DELCOGLIANO Vanarix SA Ente Ospedaliero Cantonale (EOC), Lugano
Hôpitaux Universitaire de Genève (HUG), Genève
Hirslanden Clinique la Colline, Genève
Balgrist University Hospital, Zurich
Comitato etico cantonale Ticino Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) 05.04.2024
2023-02013 Thermoablation bei Struma multinodosa - eine retrospektive Analyse personal data/biological material monocentric Prof. Dr. med. Oliver Dudeck Zentrum für Mikrotherapie - Hirslanden Klinik Zentrum für Mikrotherapie / Hirslanden Klinik, Zürich
Kantonale Ethikkommission Zürich 16.01.2024
2023-01964 SAKK 38/23 LIBERTY:
Liquid biopsy to diagnose and monitor central nervous system (CNS) involvement in high-risk B cell non-Hodgkin lymphoma
non clinical, involving persons multicentric A Dr. med. Noémie Lang SAKK HUG, Oncologie, Genève
Inselspital Bern, Bern
Kantonsspital Aarau AG, Aarau
Kantonsspital Baselland  <...> - Sion, Sion
Klinik für Hämatologie und Onkologie Hirslanden More ...
Commission Cantonale d'éthique de la recherche Genève (CCER) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 05.03.2024
2023-01933 REAL-WORLD RETROSPECTIVE STUDY OF TOTAL NEOADJUVANT THERAPY FOR RECTAL CANCER personal data/biological material monocentric Siebenhüner Department of Gastrointestinal Oncology KHO Hirslanden Zürich AG, Zürich
Kantonale Ethikkommission Zürich 09.02.2024
2023-01510 A Prospective, Post-marketing, non-interventional study of RISankizumab evaluating real-world clinical Effectiveness in Crohn’s disease (APPRISE) non clinical, involving persons multicentric A Prof. Dr. med. Frank Seibold AbbVie AG Intesto Bern, Bern
Insel Gruppe AG, Bern
Centre Crohn et Colite Gastroentérologie La Tour, Hôpital d <...> roentérologie Beaulieu SA, Lausanne
Gastrozentrum Hirslanden More ...
Kantonale Ethikkommission Bern Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonal More ... 03.01.2024
2023-01489 CAAA617D12302: An International, Prospective, Open-label, Multi-center, Randomized Phase III Study comparing lutetium (177Lu) vipivotide tetraxetan (AAA617) versus Observation to delay castration or d More ... clinical trial drugs phase 3 multicentric B PD Dr. med. Janusch Blautzik Novartis Pharma Schweiz AG Hirslanden Klinik St. Anna, Luzern
Hôpitaux universitaire de Genève, Geneva
Stadtspital Zürich,, Zürich
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) 22.11.2023
2023-01421 PREcooPera:A Window-of-Opportunity trial of giredestrant +/- triptorelin vs. anastrozole + triptorelin in premenopausal patients with ER-positive/HER2-negative early breast cancer clinical trial drugs phase 2 multicentric C Prof. Dr. med. Peter Dubsky ETOP IBCSG Partner foundation Hirslanden Klinik St. Anna, Luzern
Kantonsspital Baden, Department of Gynecology, Baden
Brustzentrum Basel Bethesda Spital, Basel
Spital Thurgau, Frauenfeld
Instituto Oncologico della Swizzera Italian More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... 09.10.2023
2023-01077 DRAGON 2 - An international multicentre randomised controlled trial to compare combined Portal and Hepatic Vein Embolization (PVE/HVE) with PVE alone. clinical trial other clinical trials multicentric B Prof. Dr. med. Stefan Breitenstein Maastricht University, School for Oncology and Reproduction Kantonsspital Winterthur, Klinik für Viszeral- und Thoraxchirurgie, Winterthur
St. Claraspital AG, Basel
Universitätsspital Basel, Basel
Hirslanden Klinik St. Anna, Luzern
Klinik Hirslanden, Zürich
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich 09.01.2024
2023-00928 A PHASE 3, RANDOMIZED, OPEN-LABEL, MULTICENTER STUDY OF ARV-471
(PF-07850327) PLUS PALBOCICLIB VERSUS LETROZOLE PLUS PALBOCICLIB
FOR THE TREATMENT OF PARTICIPANTS WITH ESTROGEN
RECEPTOR-POSITIVE, H More ...
clinical trial drugs phase 3 multicentric C Dr. med. Razvan Andrei Popescu Pfizer Inc. Tumor Zentrum Aarau Hirslanden, Aarau
CHUV (Centre Hospitalier Universitaire Vaudois), Lausanne
Ethikkommission Nordwest- und Zentralschweiz EKNZ Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 23.08.2023
2023-00749 Prevalence of PD-L1 expression in gastric and GEJ cancer patients in Switzerland personal data/biological material multicentric Dr. Alexander Siebenhüner MSD Merck Sharp & Dohme AG, Hirslanden Zürich AG, Zürich
Kantonsspital Winterthur, Winterthur
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 24.11.2023
2023-00676 Regulatory T-cells as tumor-promoting cellular partners and potential
therapeutic targets in diffuse large B-cell lymphoma.
non clinical, involving persons multicentric A Prof. Dr. Frank Stenner University Hospital Basel University Hospital Basel, Basel
Klinik für Hämatologie und Onkologie Hirslanden Zürich, Zürich
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Zürich 07.08.2023
2023-00623 Invasive Group A Streptococcus (iGAS) infection in adult population in Switzerland. A multicenter retrospective analysis personal data/biological material multicentric Pr Jacques Schrenzel HUG HUG, Geneva
Institut for Infectious Diseases, Bern
Hirslanden Klinik St Anna, Luzern
University hospital of Basel, Basel
HUG, GENEVA
Cantonal Hospital of St Gallen, St Gallen
Spital Thurgau AG, Thurga More ...
Commission Cantonale d'éthique de la recherche Genève (CCER) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 04.12.2023
2023-00541 Forecast of functional outcome and impact of anti factor Xa-levels in patients with intracerebral haemorrhage related to direct factor Xa inhibitors – a multi-center cohort study (FIRE-Xa) non clinical, involving persons multicentric A Prof. Dr. med. David Seiffge Inselspital Bern Inselspital Bern, Bern
Universitätsspital Basel, Basel
Kantonsspital St. Gallen, St. Gallen
Universitätsspital Zürich, Zürich
Klinik Hirslanden Zürich, Zürich
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich 10.08.2023