BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2022-01131 FINE-REAL: A non-interventional study providing insights into the use of finerenone in a routine clinical setting. non clinical, involving persons multicentric A Prof. Andreas Serra Bayer AG Klinik Hirslanden, Zentrum Nephrologie/Dialyse, Zürich
Engeriedspital, Riedweg 15, 3012 Bern, Bern
Kantonsspital Baselland, Nephrologie, Liestal
Kantonsspital Baden, Baden
Stoffwechselzentrum St. Gall More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... 24.08.2022
2022-01121 Crowd Working in Switzerland (CroWiS) - Association of temporary nurse staffing with adverse events - B.3 personal data/biological material multicentric Mr. Huber Cornelius-Monroe Institute of Nursing Science (INS) Kantonsspital Baselland, Basel
Universitätsspital Zürich, Zürich
Hirslanden AG, Klinik Hirslanden, Zurich
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Zürich 07.07.2022
2022-01080 FUNCTION OF THE ANTERIOR SUPERIOR ALVEOLAR NERVE IN LATERAL NASAL WALL SURGERY personal data/biological material monocentric Prof. Dr. med. Daniel Simmen Klinik Hirslanden ORL-Zentrum Klinik Hirslanden, Zürich
Kantonale Ethikkommission Zürich 24.08.2022
2022-00799 VICTORION REAL: An international prospective Real-world study to evaluate the Effectiveness and Adherence of incLisiran plus standard of care lipid-lowering therapy compared to standard of care therap More ... non clinical, involving persons multicentric A Prof Mach Francois Novartis Pharma AG Hopitaux Universitaires de Geneve, Genève
HerzKlinik Hirslanden, Witellikerstrasse 40, Zürich
Commission Cantonale d'éthique de la recherche Genève (CCER) Kantonale Ethikkommission Zürich 09.08.2022
2022-00677 ENDOSCOPIC VACUUM THERAPY FOR PATIENTS WITH UPPER GASTRO-INTESTINAL TRANSMURAL DEFECTS: A RETROSPECTIVE AND PROSPECTIVE MULTI-CENTER COHORT STUDY personal data/biological material monocentric Prof. Dr. med. Stefan Seewald Amsterdam University Medical Center Gastrozentrum Hirslanden, Zürich
Kantonale Ethikkommission Zürich 10.06.2022
2022-00641 A Phase 3, Randomized, Open-label (Sponsor Blinded) Study of Relatlimab-nivolumab Fixeddose Combination Versus Regorafenib or Trifluridine + Tipiracil (TAS-102) for Participants with Later-lines of Me More ... clinical trial drugs phase 3 multicentric C Dr. med. Razvan Popescu Bristol-Myers Squibb International Corporation Privatklinikgruppe Hirslanden - Hirslanden Klinik Aarau, Aarau
Universitätsspital Bern - Inselspital - Universitätsklinik für Medizinische Onkologie, Bern
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern 03.11.2022
2022-00444 Patient-derived organoid generation in pancreatic cancer: a single centre, open-label, single arm feasibility study. non clinical, involving persons monocentric A Prof. Dr. med. Dres. h.c. Jan Schmidt, MME Hirslanden Hospitals, Zürich
Kantonale Ethikkommission Zürich 21.07.2022
2022-00384 SURveillance of infectious diseases among health PRofessionals In SwitzErland –
a longitudinal, multicentre open cohort
non clinical, involving persons multicentric A PD Dr. Philipp Kohler Cantonal Hospital St.Galen, Division of Infectious Deseas Division of Infectious Diseases, St. Gallen
Clienia Littenheid AG, 9573 Littenheid
Spital Thurgau AG <...> rg, 9500 Wil
Ostschweizer Kinderspital, St.Gallen
Hirslanden More ...
Ethikkommission Ostschweiz (EKOS) Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich 03.03.2022 yes
2022-00242 Lymphvenöse Anastomosen bei Lappenrekonstruktionen vom postoperativen Defekt bei Sarkompatienten. personal data/biological material monocentric pract. med. Audrius Poskevicius Hirslanden Klinik St. Anna Hirslanden Klinik St. Anna, Luzern
Ethikkommission Nordwest- und Zentralschweiz EKNZ 22.03.2022
2021-D0077 ePRO for the Timely Detection of Side Effects in Cancer Patients Undergoing CAR T Immunotherapy: Feasibility Study clinical trial medical devices monocentric A1 PD Dr. med. Panagiotis Samaras Stiftung Swiss Tumor Institute Klinik für Hämatologie und Onkologie Hirslanden, Zürich
Kantonale Ethikkommission Zürich 01.02.2022 Study has ended
2021-D0051 HER2-directed Biosimilar OgivriTM in Breast Cancer: Real world Observational trial for the description of Quality of Life and Outcome using ePRO (OGIPRO- Trial) clinical trial medical devices multicentric A1 Prof. Andreas Trojan Mobile Health AG SeeSpital Horgen, Horgen
Spitalzentrum Oberwallis (SZO), Brig
Tumorcenter Hirslanden, Rain 34
Tumorzentrum ZeTuP Rapperswil-Jona, Alte Jonastrasse 24
Tumor- und Brustzentrum ZeTuP St.Gallen, Rorschach More ...
Kantonale Ethikkommission Zürich Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Ethikkommission Nor More ... 03.12.2021
2021-02300 A multicenter, cluster-randomized superiority trial of a guideline-based family support intervention in intensive care units clinical trial other clinical trials multicentric A Rahel Naef University of Zurich (UZH) & University Hospital Zurich (USZ) Universität Zürich, Zürich
Inselspital Bern, Universitätsklinik für Intensivmedizin, Bern
Lindenhofs <...> bünden, Chur
Kantonsspital Winterthur, Winterthur
Hirslanden More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 28.01.2022
2021-01872 SAKK 06/19
Intravesical recombinant BCG followed by perioperative chemo-immunotherapy for patients with muscle-invasive bladder cancer (MIBC).
A multicenter, single-arm phase II trial
clinical trial pathogenic organisms / gmo multicentric C PD Dr. med. Richard Cathomas SAKK Kantonsspital Graubünden, Chur
Lindenhofspital, Bern
Universitätsspital Basel, Basel
Kantonsspital B <...> llinzona
Universitätsspital Zürich, Zürich
Klinik Hirslanden More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche G More ... 25.03.2022
2021-01863 Venetoclax AML Observational Real-World study of treatment-naïve patients ineligible for intensive chemotherapy in Switzerland & Austria (VALOR) non clinical, involving persons multicentric A Dr. med. Michael Grogor AbbVie Hämatologie LUKS, Luzern
Inselspital, Bern
Spitalzentrum Oberwallis, Brig
Kantonsspital Baden, Baden <...> ital de Nyon - GHOL, Nyon
Hopital du Valais, Sion
Hirslanden More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 24.11.2021
2021-01836 Deciphering the complex interaction between inflammation and mechanical injury in the pathogenesis of osteoarthritis: Is lipopolysaccharide the culprit? personal data/biological material multicentric Prof. Dr. Marcy Zenobi-Wong ETH Zürich ETH, Zürich
Schulthess Klinik / Hüftchirugie, Zürich
Schulthess Klinik / Kniechirugie, Zürich
Spital Hirslanden, Zürich
Klinik für Rheumatologie / USZ, Zürich
USZ / Klinik für Traumatologie, Zürich
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 04.03.2022
2021-01799 A PHASE III, RANDOMIZED, OPEN-LABEL, MULTICENTER STUDY EVALUATING THE EFFICACY AND SAFETY OF ADJUVANT GIREDESTRANT COMPARED WITH
PHYSICIAN'S CHOICE OF ADJUVANT ENDOCRINE MONOTHERAPY IN PATIENTS
WITH More ...
clinical trial drugs phase 3 multicentric C Dr. Ursina Zürrer F. Hoffmann-La Roche Ltd Kantonsspital Winterthur, Med. Onkologie und Hämatologie, Winterthur
Spital STS AG, Onkologiezentrum Thun-Berner Oberland, Thun
Inselspital, Universitätsklinik für Medizinische Onkologie, Bern
Hirslanden More ...
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 12.11.2021
2021-01768 Decision Making and Outcome of Surgical and Percutaneous Aortic valve Interventions: TAVI vs Mini-AVR, a retrospective, single-center analysis 2013 – 2020 personal data/biological material monocentric Prof. Dr. med. / Georg / Noll HerzKlinik Hirslanden HerzKlinik Hirslanden, Zürich
Kantonale Ethikkommission Zürich 19.11.2021
2021-01660 SUPER-COVID - SUPERINFECTIONS IN PATIENTS WITH COVID-19 personal data/biological material multicentric Prof. Werner Albrich Kantonsspital St. Gallen Kantonsspital St. Gallen, St. Gallen
Hirslanden Klinik St. Anna, Luzern
Luzerner Kantonsspital/Kinderspital, Luzern
Universitätspital Basel, Basel
Hôpital Cantonal, Genève
Spital Thurgau AG, Münsterli More ...
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) 12.08.2021
2021-01659 A phase IIb, double-blind, randomised, placebo-controlled trial to evaluate
the efficacy and tolerability of ZED1227 in celiac disease subjects
experiencing symptoms despite gluten-free diet
clinical trial drugs phase 2 multicentric C PD Dr. Jonas Zeitz Dr. Falk Pharma GmbH GastroZentrum Hirslanden, Zürich
INSELSPITAL, Universitätsspital Bern, Klinik für Viszerale Chirurgie und Medizin, Gastroenterologie, Bern
Kantonsspital St.Gallen, Klinik für Gastroenterologie und Hep More ...
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 17.09.2021
2021-01521 OUTCOMES OF ENDOSCOPICALLY RESECTED HIGH-RISK MUCOSAL ADENOCARCINOMA AND LOW- AND HIGH-RISK SUBMUCOSAL ADENOCARCINOMA ARISING IN BARRETT’S ESOPHAGUS: AN INTERNATIONAL MULTICENTER RETROSPECTIVE COHORT More ... personal data/biological material monocentric Prof. Stefan Seewald Amsterdam University Medical Centre Gastrozentrum Hirslanden, Zurich
Kantonale Ethikkommission Zürich 17.08.2021