| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-D0042 | CT-Guided Interventions using a patient mounted navigation system: Initial Clinical Experience | clinical trial | medical devices | monocentric | A1 | Dr. Med. Sebastian Kos | Universitätsspital Basel |
Klinik Hirslanden St. Anna, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.07.2023 | |||||
| 2023-00541 | Forecast of functional outcome and impact of anti factor Xa-levels in patients with intracerebral haemorrhage related to direct factor Xa inhibitors – a multi-center cohort study (FIRE-Xa) | non clinical, involving persons | multicentric | A | PD Dr. med. David Seiffge | Inselspital Bern |
Inselspital Bern, Bern Universitätsspital Basel, Basel Kantonsspital St. Gallen, St. Gallen Universitätsspital Zürich, Zürich Klinik Hirslanden Zürich, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 10.08.2023 | |||||
| 2023-00398 |
SAKK_LuCa_2 Retrospective and prospective registry of patients with metastatic NSCLC harboring typical and atypical EGFR mutations |
personal data/biological material | multicentric | Dr. med. Sabine Schmid | SAKK |
Inselspital Bern, Bern Kantonsspital Aarau, Aarau Tumor Zentrum Aarau Hirslanden Medical Center, Aarau Kantonsspital Baden, Baden St. Claraspital, Basel Luzerner Kantonsspital, Luzern Kantonsspital St More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 07.06.2023 | ||||||
| 2023-00313 | Long-Term outcomes of minimally invasive aortic valve replacement performed through a right anterior mini-thoracotomy | personal data/biological material | monocentric | PD Dr. Diana Reser | Witellikerstrasse 40 |
Herzklinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 10.08.2023 | |||||||
| 2023-00253 | Empagliflozin functional capacity - Non-Interventional Study Emp-Activity | non clinical, involving persons | multicentric | A | Prof. Dr. med. Matthias Hermann | Boehringer Ingelheim (Schweiz) GmbH |
Universitätsspital Zürich, Zürich Spitalzentrum Biel, Biel Spital Thun, Thun Spital Sonnenhof, Bern <...> l, Waltenschwil Spital Lachen, Lachen Herzzentrum Hirslanden More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 25.04.2023 | |||||
| 2023-00034 |
HI-REA Retrospektive Analyse von Einsatzprotokollen des Reanimationsteams eines tertiären Versorgungszentrums über einen Zeitraum von Januar 2012- Dezember 2022 mit Beschreibung des klinischen Spektr More ... |
personal data/biological material | monocentric | Prof. Dr. med. / Christophe / Wyss | HerzKlinik Hirslanden |
HerzKlinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 17.03.2023 | |||||||
| 2022-D0107 | A post-market registry study based on standard clinical care to assess safety and performance of RefluxStop™ in the treatment of Gastroesophageal Reflux Disease (GERD) in general hospital practice. | clinical trial | medical devices | multicentric | A1 | Dr. med. / Yves / Borbély | Implantica CE Reflux Ltd. |
Inselspital, Bauchzentrum, Bern Hirslanden Klinik Beau‐Site Bern, Bern |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 29.11.2022 | ||||
| 2022-02297 | Snap Shot Audit Early Onset Colorectal Cancer (EOCC) - Are we doing enough or can we do more? | personal data/biological material | multicentric | PD Dr. med. Marco von Strauss |
Clarunis, Basel Lindenhof Spital, Bern Spitalzentrum Biel, Biel Spital Wallis, Visp Kantonsspital Aarau, Aarau Kantonsspital Olten, Olten Kantonsspital Baselland, Liestal Kantonsspital Luzern, Luzern Hirslanden More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 28.03.2023 | |||||||
| 2022-02171 | A PHASE 3, RANDOMIZED, OPEN-LABEL, MULTICENTER TRIAL OF ARV-471 (PF-07850327) VS FULVESTRANT IN PARTICIPANTS WITH ESTROGEN RECEPTOR-POSITIVE, HER2-NEGATIVE ADVANCED BREAST CANCER WHOSE DISEASE PROGRES More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Razvan Andrei Popescu | Pfizer Inc. |
Tumor Zentrum Aarau Hirslanden Medical Center, Aarau Spital Thurgau AG Kantonsspital Frauenfeld, Frauenfeld Ospedale Regionale Bellinzona e Valli IOSI, Bellinzona Kantonsspital Graubünden Onkologie/ More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 25.04.2023 | |||
| 2022-02083 | 20604, OCEANIC-STROKE: A multicenter, international, randomized, placebo controlled, double-blind, parallel group and event driven Phase 3 study of the oral FXIa inhibitor asundexian (BAY 2433334) for More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. GM De Marchis | Bayer (Schweiz) AG |
Kantonsspital, St. Gallen Inselspital Bern, Neurologie und Stroke Center, Bern Universitätsspital Ba <...> l Cantonal / Kantonsspital, Fribourg NeuroZentrum Hirslanden More ... |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... | 02.02.2023 | |||
| 2022-02081 | A Phase 3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients with Autosomal Dominant Polycystic Kidney Disease | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Andreas Serra | Reata Pharmaceuticals, Inc. |
Klinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 14.02.2023 | yes | Study has ended | ||
| 2022-01131 | FINE-REAL: A non-interventional study providing insights into the use of finerenone in a routine clinical setting. | non clinical, involving persons | multicentric | A | Prof. Andreas Serra | Bayer AG |
Klinik Hirslanden, Zentrum Nephrologie/Dialyse, Zürich Engeriedspital, Riedweg 15, 3012 Bern, Bern Kantonsspital Baselland, Nephrologie, Liestal Kantonsspital Baden, Baden Stoffwechselzentrum St. Gall More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... | 24.08.2022 | |||||
| 2022-01121 | Crowd Working in Switzerland (CroWiS) - Association of temporary nurse staffing with adverse events - B.3 | personal data/biological material | multicentric | Mr. Huber Cornelius-Monroe | Institute of Nursing Science (INS) |
Kantonsspital Baselland, Basel Universitätsspital Zürich, Zürich Hirslanden AG, Klinik Hirslanden, Zurich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 07.07.2022 | ||||||
| 2022-01080 | FUNCTION OF THE ANTERIOR SUPERIOR ALVEOLAR NERVE IN LATERAL NASAL WALL SURGERY | personal data/biological material | monocentric | Prof. Dr. med. Daniel Simmen | Klinik Hirslanden |
ORL-Zentrum Klinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 24.08.2022 | |||||||
| 2022-00932 | The Malignant Potential of Pancreatic Cysts: Artificial Intelligence Applied to Imaging and Clinical features | personal data/biological material | multicentric | PD Dr Martin Bolli | Clarunis University Center for Gastrointestinal and Liver Diseases Basel |
Clarunis Unversity Center for Gastrointestinal and Liver Diseases, Basel Hirslanden Klinik Beau-Site, Bern Lindenhofspital, Bern Spitalzentrum Oberwallis, Visp Kantonsspital Baselland, Liestal Hirslan More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.07.2022 | ||||||
| 2022-00677 | ENDOSCOPIC VACUUM THERAPY FOR PATIENTS WITH UPPER GASTRO-INTESTINAL TRANSMURAL DEFECTS: A RETROSPECTIVE AND PROSPECTIVE MULTI-CENTER COHORT STUDY | personal data/biological material | monocentric | Prof. Dr. med. Stefan Seewald | Amsterdam University Medical Center |
Gastrozentrum Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 10.06.2022 | |||||||
| 2022-00647 |
Encorafenib and cetuximab in patients with metastatic, BRAFV600E-mutated, colorectal carcinoma: a multi-centric, national, prospective, longitudinal, non-interventional study in Switzerland – BERI More ... |
non clinical, involving persons | multicentric | A | Dr. Melanie Löffler-Baumann | Pierre Fabre Pharma AG |
Claraspital Basel, Basel Kouros Moccia Oncologia, 6600 Locarno HFR Freiburg - Kantonskrankenhaus, On <...> ubünden, Onkologie, Hämatologie, 7000 Chur Klinik Hirslanden More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 27.07.2022 | |||||
| 2022-00641 | A Phase 3, Randomized, Open-label Study of Relatlimab-nivolumab Fixeddose Combination Versus Regorafenib or Trifluridine + Tipiracil (TAS-102) for Participants with Later-lines of Metastatic Colorecta More ... | clinical trial | combination drugs/devices | phase 3 | multicentric | C | Dr. med. Razvan Popescu | Bristol-Myers Squibb International Corporation |
Privatklinikgruppe Hirslanden - Hirslanden Klinik Aarau, Aarau Universitätsspital Bern - Inselspital - Universitätsklinik für Medizinische Onkologie, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 03.11.2022 | |||
| 2022-00584 | Wearable sensors for delirium detection at an early stage (WeSen_delirium) – an exploratory study | non clinical, involving persons | multicentric | A | PD Dr. Martina Kleber | Department of Internal Medicine, University Hospital of Zurich |
University Hospital Zurich, Zurich Klnik Hirslanden, 8032 Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 15.07.2022 | |||||
| 2022-00544 |
SteamOne Prospective Registry Database for Rezum water vapor therapy of the prostate |
non clinical, involving persons | multicentric | A | PD Dr. med. Jan Ebbing | University Hospital Basel |
University Hospital Basel, Basel Kantonsspital Aarau AG,, Aarau Hirslandenklinik St. Anna, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.07.2022 | |||||