| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-D0058 | A blinded randomized clinical investigation of RefluxStop™ compared with Nissen fundoplication in the treatment of Gastroesophageal Reflux Disease (GERD). | clinical trial | medical devices | multicentric | A1 | Dr. med, Professor (USC) Jörg Zehetner | Implantica CE Reflux Ltd |
Klinik Beau-Site Hirslanden Bern, Swiss1Chirurgie AG, Bern Inselspital, Universitätsspital Bern, 3010 Bern |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 26.08.2024 | ||||
| 2024-D0054 | CLARITY-Gastric01 - A Phase III Multi-center, Open-label, Sponsor-blinded, Randomized Study of AZD0901 Monotherapy Compared with Investigator’s Choice of Therapy in Second- or Later-Line Adult Partici More ... | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C2 | Dr med Alexander Siebenhüner | AstraZeneca |
Klinik für Hämatologie und Onkologie Hirslanden Zürich AG , Witellikerstrasse 40, 8032 Zürich INSELSPITAL Universitätsspital Bern Universitätsklinik für medizinische Onkologie Klinische Forschungseinh More ... |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève More ... | 22.11.2024 | ||||
| 2024-D0037 | The DEXTER-assisted non-emergent and acute cholecystectomy Study | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Stefan Breitenstein | Distalmotion SA |
Kantonsspital Winterthur, Winterthur Centre Hospitalier Universitaire Vaudois, Rue du Bugnon 46 Hirslanden Zurich, Chirurgisches Zentrum Zürich Witellikerstrasse 40 |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Zürich | 14.06.2024 | ||||
| 2024-01721 | Prospektive Beobachtungsstudie zur leitliniengerechten Therapie bei Astrozytomen und Oligodendrogliomen, WHO Grad 2, mit IDH1/2 Mutation | personal data/biological material | monocentric | Dr. med. Dr. phil. Jonas Klöpper | Klinik Hirslanden Zürich |
Klinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 08.11.2024 | |||||||
| 2024-01674 | The outcome of patients undergoing rescue stenting in Switzerland – An analysis of the Swiss Stroke Registry | personal data/biological material | multicentric | Prof. Marios Psychogios | Universitätsspital Basel |
Universitätsspital Basel, Neuroradiology, Basel Inselspital Bern, Bern Kantonsspital Luzern, Luzern <...> Lausanne Universitätsspital Zürich, Zürich Klinik Hirslanden More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 03.10.2024 | ||||||
| 2024-01643 | Cardiotoxicity associated with the use of Venlafaxine: retrospective analysis of five patients | personal data/biological material | monocentric | Prof. Dr. med. Christine Attenhofer Jost | HerzGefässZentrum Klinik im Park Hirslanden |
HerzGefässZentrum Klinik im Park, Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 15.10.2024 | |||||||
| 2024-01481 | Effects of beginning a GLP1-Agonist therapy on residual gastric content and gastric emptying: A prospective ultrasound approach with focus on perioperative aspiration risk. | non clinical, involving persons | monocentric | A | Professor Dr. med Michael Ganter | Hirslanden Klinik Zürich |
Hirslanden Klinik Zürich, Zürich |
Kantonale Ethikkommission Zürich | 24.09.2024 | ||||||
| 2024-01205 | C4391022 / AN INTERVENTIONAL, OPEN-LABEL, RANDOMIZED, MULTICENTER PHASE 3 STUDY OF PF-07220060 PLUS FULVESTRANT COMPARED TO INVESTIGATOR’S CHOICE OF THERAPY IN PARTICIPANTS OVER 18 YEARS OF AGE WITH More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Razvan Popescu | Pfizer Inc. |
Tumor Zentrum Aarau - Hirslanden Medical Center, Aarau Solothurner Spitäler AG - Kantonsspital Olten, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.07.2024 | |||
| 2024-01181 | Évaluation de la reproductibilité d’un test de fatigue isométrique quadricipital réalisé sur dynamomètre isocinétique | non clinical, involving persons | monocentric | A | Alexandre Joye | Université de Lausanne - Institut des Sciences du Sport |
HIRSLANDEN Clinique La Colline - Centre de Médecine du Sport et de l'Exercice (CMSE), Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.11.2024 | ||||||
| 2024-00871 | Feasibility of treadmill exercise echocardiography to identify exercise induced pulmonary hypertension in everyday practice | personal data/biological material | monocentric | Prof. Dr. med. Christine Attenhofer Jost | HerzGefässZentrum im Park, Klinik Im Park, Hirslanden |
HerzGefässZentrum Im Park, Klinik im Park, Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 18.06.2024 | |||||||
| 2024-00764 | Analysis of 177[Lu]Lu-PSMA-I&T Outcomes in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Post-Taxane Setting Through the European Early Access Program | personal data/biological material | multicentric | Dr. med. Maria del Sol Pérez Lago | Curium Holding France |
Kantonsspital Luzern, Luzern Inselspital Bern, Bern Hirslanden Klinik St. Anna, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 22.08.2024 | ||||||
| 2023-D0107 | A Non-Randomized, Prospective or Retrospective, Open-Label, Multi-Center, Observational Clinical Study with Two Arms to Further Evaluate Safety and Performance of the NEXUS® Aortic Arch Stent Graft Sy More ... | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Mario Lachat | Endospan ltd |
Hirslanden Klinik, Zürich |
Kantonale Ethikkommission Zürich | 12.12.2023 | |||||
| 2023-D0097 |
CAMBRIA-2 (ClinO-MD) A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next-Generation, Oral Selective Estrogen Receptor Degrader) Versus Standar More ... |
clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C2 | Dr. med. Ursina Zürrer-Härdi | AstraZeneca AB |
Kantonsspital Winterthur, Klinik für Medizinische Onkologie und Hämatologie, Winterthur Kantonsspital Baden, Im Ergel Hirslandenklinik St. Anna, Zentrum für Onkologie St. Anna-Strasse 32 Universitäts More ... |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, More ... | 28.03.2024 | ||||
| 2023-D0092 | Mid- oder high-flex Stäbe versus low-flex Stäbe von SpineShape System IV zur Behandlung der degenerativen Lendenwirbelsäule - eine prospektive, multizentrische, randomisiert kontrollierte Non-Inferior More ... | clinical trial | medical devices | multicentric | C3 | Dr. med. Philipp Cathrein | SpineSave AG |
Hirslanden Klinik Linde, Biel Spital Aarberg, Aarberg |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 27.02.2024 | ||||
| 2023-D0042 | CT-Guided Interventions using a patient mounted navigation system: Initial Clinical Experience | clinical trial | medical devices | monocentric | A1 | Dr. Med. Sebastian Kos | Universitätsspital Basel |
Klinik Hirslanden St. Anna, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.07.2023 | |||||
| 2023-02353 | A phase II, double-blind, randomised, placebo-controlled trial to evaluate the efficacy and tolerability of ZED1227 in celiac disease subjects experiencing symptoms despite gluten-free diet | clinical trial | drugs | phase 2 | multicentric | C | PD Dr.med. Jonas Zeitz | Dr. Falk Pharma GmbH |
GastroZentrum Hirslanden, CH-8032 Zürich Inselspital Bern , Freiburgstr. 18, CH-3010 Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 09.08.2024 | |||
| 2023-02200 | GO44145 - A PHASE III, MULTICENTER, RANDOMIZED, OPEN‑LABEL STUDY COMPARING THE EFFICACY AND SAFETY OF GLOFITAMAB (RO7082859) IN COMBINATION WITH POLATUZUMAB VEDOTIN PLUS RITUXIMAB, CYCLOPHOSPHAMIDE, D More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Frank Stenner | Roche Pharma (Schweiz) AG |
Universitätsspital Basel, Basel Hirslanden - Klinik im Park; OnkoZentrum Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 24.04.2024 | |||
| 2023-02168 | Implantation of Allogenic Cartilage Mini-grafts: First-In-Human Study for Treating Chondral Lesions of the Knee. Open Cohort, Small Sample Size with 6 months Follow-Up | clinical trial | transplant products | multicentric | C | Dr Marco DELCOGLIANO | Vanarix SA |
Ente Ospedaliero Cantonale (EOC), Lugano Hôpitaux Universitaire de Genève (HUG), Genève Hirslanden Clinique la Colline, Genève Balgrist University Hospital, Zurich |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 05.04.2024 | ||||
| 2023-02013 | Thermoablation bei Struma multinodosa - eine retrospektive Analyse | personal data/biological material | monocentric | Prof. Dr. med. Oliver Dudeck | Zentrum für Mikrotherapie - Hirslanden Klinik |
Zentrum für Mikrotherapie / Hirslanden Klinik, Zürich |
Kantonale Ethikkommission Zürich | 16.01.2024 | |||||||
| 2023-01964 |
SAKK 38/23 LIBERTY: Liquid biopsy to diagnose and monitor central nervous system (CNS) involvement in high-risk B cell non-Hodgkin lymphoma |
non clinical, involving persons | multicentric | A | Dr. med. Noémie Lang | SAKK |
HUG, Oncologie, Genève Inselspital Bern, Bern Kantonsspital Aarau AG, Aarau Kantonsspital Baselland <...> is, Lausanne Klinik für Hämatologie und Onkologie Hirslanden More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 05.03.2024 | |||||