| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-D0034 | Robotic minimAlly invasive Ventral HErNia repair with Dexter® | clinical trial | medical devices | multicentric | A1 | Dr. Med. Nico Seeger | Distalmotion SA |
Kantonsspital Winterthur, Winterthur Viscera Bauchmedizin Bern, Bern Hirslanden Klinik, Witellikerstrasse 40 |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 06.06.2025 | Study has ended | |||
| 2025-02468 | Long-Term Use of Guselkumab: Non-interventional Assessment of Real-world Outcomes LUNAR | non clinical, involving persons | multicentric | A | Prof. Dr. med. Emanuel Burri | Janssen-Cilag AG |
Kantonspital Baselland, Liestal Intesto Bern, Bern Insel Gruppe AG, Universitätsspital Bern, Bern ,H <...> enterologie und Hepatologie, Zürich GastroZentrum Hirslanden More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonal More ... | 02.02.2026 | |||||
| 2025-01631 | Long-term Clinical Outcomes after Allogenic Cartibeads Implantation in Knee Chondral Lesions: 1, 2 and 5-years Follow-Up | non clinical, involving persons | multicentric | A | Dr. Marco Delcogliano | Vanarix SA |
EOC / LOGMedica, Lugano HUG, Geneva Clinique Hirslanden La Colline, Geneva Balgrist University Hospital, Zurich |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.01.2026 | |||||
| 2025-01460 |
OPBC-10/NOAX Axillary radiotherapy or axillary lymph node dissection in patients with clinically node-positive breast cancer undergoing upfront tailored axillary surgery: An international, randomi More ... |
clinical trial | other clinical trials | multicentric | B | Prof. Dr. med. Walter Paul Weber | University Hospital Basel |
University Hospital Basel, Basel Brustzentrum Luzern, Luzerner Kantonsspital, Luzern Kantonsspital Baden, Baden Hirslanden Klinik St. Anna, Luzern Bethesda Spital Basel, Pratteln HUG – Hôpitaux Univer More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 11.08.2025 | ||||
| 2025-01408 |
20230239 - A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig Plus Abiraterone Versus Investigator’s Choice in Participants with Chemotherapy-naïve Metastatic Castration-resistant Pr More ... |
clinical trial | drugs | phase 3 | multicentric | C | Dr. Med Stefanie Fischer | Amgen Inc. |
HOCH Health Ostschweiz Kantonsspital Sankt Gallen, Sankt Gallen Inselspital Bern, Bern Centre Hospitalier Universitaire Vaudois, Lausanne Klinik Hirslanden, Zurich |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.10.2025 | |||
| 2025-01232 | A Phase 3, randomized, double-blind, placebo-controlled, multicenter, clinical trial with extension period to evaluate the efficacy and safety of Xeomin® injections for the prevention of episodic migr More ... | clinical trial | drugs | phase 3 | multicentric | B | Dr. Reto Agosti | Merz Therapeutics GmbH |
Kopfwehzentrum Hirslanden, Neurologica GmbH, Zollikon Inselspital Bern, Universitätsklinik für Neurologie, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 05.09.2025 | |||
| 2025-01231 |
A Phase 3, randomized, double-blind, placebo-controlled, multicenter, clinical trial with extension period to evaluate the efficacy and safety of Xeomin® injections for the prevention of chronic m More ... |
clinical trial | drugs | phase 3 | multicentric | B | Dr. Reto Agosti | Merz Therapeutics GmbH |
Kopfwehzentrum Hirslanden, Neurologica GmbH, Zollikon Universitätsklinik für Neurologie, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 02.09.2025 | |||
| 2025-01227 | Heart Team Approach in Treatment of Mitral Regurgitation: Patient Selection und Longterm Outcome. | personal data/biological material | monocentric | Prof. Dr. med. Patric Biaggi | HerzKlinik Hirslanden |
HerzKlinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 05.09.2025 | |||||||
| 2025-00688 | Characterising chronic respiratory disease with the forced oscillation technique and exploring its potential for early detection of exacerbations: A cross-sectional multicentre study with a nested lon More ... | non clinical, involving persons | multicentric | A | Prof Dr. Milo A Puhan | University of Zurich |
University of Zurich, EBPI, Zurich Localmed Ärztezentrum Gurmels, Gurmels Kantonsspital Baselland, L <...> hur, Winterthur Spital Uster, Uster Lungenzentrum Hirslanden More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 11.07.2025 | |||||
| 2025-00630 | A Prospective, Multinational Study of Real-Life Current Standards of Care in Patients with Relapsed and/or Refractory Multiple Myeloma (MoMMent) | non clinical, involving persons | multicentric | A | Dr. med. Martina Bertschinger | Janssen-Cilag International NV, Beerse, Belgium |
Cantonal Hospital Winterthur - Medical Oncology, 8401 Winterthur Clinic for Hematology & Oncology, Hirslanden AG Zurich, Zurich Universitätsspital Zürich, Klinik für Medizinische Onkologie und Hämatol More ... |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 18.07.2025 | |||||
| 2025-00505 | Clinical and radiological long-term outcome after microsurgical cervical discectomy and stand-alone cage implantation | non clinical, involving persons | monocentric | A | Prof. Dr. med. Javier Fandino | Klinik Hirslanden Zürich |
Klinik Hirslanden Zürich, Zürich |
Kantonale Ethikkommission Zürich | 14.10.2025 | ||||||
| 2025-00482 | Hospital at Home versus Inpatient Care: Costs and Effectiveness | non clinical, involving persons | multicentric | A | Kilian Brändle | Hospital at Home AG |
Hospital at Home AG, Zollikon Klinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 08.08.2025 | |||||
| 2025-00443 | Artificial Intelligence Semantic Segmentation Technology Assisting Transcatheter Mitral Edge-to-Edge Repair | personal data/biological material | monocentric | Prof. Maurizio Taramasso |
HerzZentrum Hirslanden Zürich, Zürich |
Kantonale Ethikkommission Zürich | 19.08.2025 | ||||||||
| 2025-00373 |
Moving towards an optimized acute management and prevention of ischemic wake-up strokes |
personal data/biological material | monocentric | Prof.Dr.med. Nils Peters | Klinik Hirslanden |
Hirslanden Clinic, Zurich |
Kantonale Ethikkommission Zürich | 22.08.2025 | |||||||
| 2025-00372 | Genderspecific outcome of coronary bypass patients discussed in a heart team | personal data/biological material | monocentric | Prof. Dr. med. Diana Reser |
HerzKlinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 25.07.2025 | ||||||||
| 2025-00335 |
SAKK 21/23 NEODOXy Targeting cancer stem cells with NEOadjuvant DOXYcycline in patients with early ER+/HER2- breast cancer. A prospective, multicenter, single arm, open label phase II trial |
clinical trial | drugs | phase 2 | multicentric | B | Dr. med. Zaman | Swiss Cancer Institute |
CHUV, Lausanne Tumor Zentrum Aarau, Hirslanden Medical Center, Aarau HOCH Healt Ostschweiz Kantonsspital St. Gallen, St.Gallen Tumor- und BrustZentrum Ostschweiz, St.Gallen Clinique de Genolier, Genol More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.06.2025 | |||
| 2025-00301 | Incidence of Slow Delta EEG Frequencies (0.1–1 Hz) before Burst Suppression: A Prospective Observational Pilot Study | non clinical, involving persons | multicentric | A | Dr med. Anita Lüthy | University Hospital of Bern (Inselspital) |
Kantonsspital Aarau, Aarau Hirslanden Klinik Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.06.2025 | |||||
| 2025-00208 | Outcome after comprehensive treatment of intracranial astrocytoma and oligodendroglioma WHO 2 | personal data/biological material | monocentric | Prof. Dr. med. Javier Fandino | Neurochirurgische Klinik Hirslanden Zürich |
Klinik für Neurochirurgie, Hirslanden Zürich, Zürich |
Kantonale Ethikkommission Zürich | 27.06.2025 | |||||||
| 2025-00129 | Radiation exposure from coronary CT angiography in a real-world setting. | personal data/biological material | monocentric | Prof. Dr. med. Oliver Gämperli | HerzKlinik Hirslanden |
HerzKlinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 04.04.2025 | |||||||
| 2025-00060 | The predictive value of preinterventional radiological findings in patients undergoing invasive treatment for trigeminal neuralgia | personal data/biological material | multicentric | Prof. Dr. med. Javier Fandino | Klinik für Neurochirurgie |
Zentrum für Neurochirurgie, Zürich Klinik für Neurochirurgie - Hirslanden Klinik Aarau, Aarau |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 24.06.2025 | ||||||