| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-D0107 | A Non-Randomized, Prospective or Retrospective, Open-Label, Multi-Center, Observational Clinical Study with Two Arms to Further Evaluate Safety and Performance of the NEXUS® Aortic Arch Stent Graft Sy More ... | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Mario Lachat | Endospan ltd |
Hirslanden Klinik, Zürich |
Kantonale Ethikkommission Zürich | 12.12.2023 | |||||
| 2023-D0097 |
CAMBRIA-2 (ClinO-MD) A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Camizestrant (AZD9833, a Next-Generation, Oral Selective Estrogen Receptor Degrader) Versus Standar More ... |
clinical trial | in vitro diagnostic medical devices | multicentric | C2 | Dr. med. Ursina Zürrer-Härdi | AstraZeneca AB |
Kantonsspital Winterthur, Klinik für Medizinische Onkologie und Hämatologie, Winterthur Kantonsspital Baden, Im Ergel Hirslandenklinik St. Anna, Zentrum für Onkologie St. Anna-Strasse 32 Spital Thurg More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Comitato etico cantonale Ticino | 28.03.2024 | ||||
| 2023-D0092 | Mid- oder high-flex Stäbe versus low-flex Stäbe von SpineShape System IV zur Behandlung der degenerativen Lendenwirbelsäule - eine prospektive, multizentrische, randomisiert kontrollierte Non-Inferior More ... | clinical trial | medical devices | multicentric | C3 | Dr. med. Philipp Cathrein | SpineSave AG |
Hirslanden Klinik Linde, Biel Spital Aarberg, Aarberg |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 27.02.2024 | ||||
| 2023-D0042 | CT-Guided Interventions using a patient mounted navigation system: Initial Clinical Experience | clinical trial | medical devices | monocentric | A1 | Dr. Med. Sebastian Kos | Universitätsspital Basel |
Klinik Hirslanden St. Anna, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.07.2023 | |||||
| 2023-02168 | Implantation of Allogenic Cartilage Mini-grafts: First-In-Human Study for Treating Chondral Lesions of the Knee. Open Cohort, Small Sample Size with 6 months Follow-Up | clinical trial | transplant products | multicentric | C | Dr Marco DELCOGLIANO | Vanarix SA |
Ente Ospedaliero Cantonale (EOC), Lugano Hôpitaux Universitaire de Genève (HUG), Genève Hirslanden Clinique la Colline, Genève Balgrist University Hospital, Zurich |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 05.04.2024 | ||||
| 2023-02013 | Thermoablation bei Struma multinodosa - eine retrospektive Analyse | personal data/biological material | monocentric | Prof. Dr. med. Oliver Dudeck | Zentrum für Mikrotherapie - Hirslanden Klinik |
Zentrum für Mikrotherapie / Hirslanden Klinik, Zürich |
Kantonale Ethikkommission Zürich | 16.01.2024 | |||||||
| 2023-01964 |
SAKK 38/23 LIBERTY: Liquid biopsy to diagnose and monitor central nervous system (CNS) involvement in high-risk B cell non-Hodgkin lymphoma |
non clinical, involving persons | multicentric | A | Dr. med. Noémie Lang | SAKK |
HUG, Oncologie, Genève Inselspital Bern, Bern Kantonsspital Aarau AG, Aarau Kantonsspital Baselland <...> - Sion, Sion Klinik für Hämatologie und Onkologie Hirslanden More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 05.03.2024 | |||||
| 2023-01933 | REAL-WORLD RETROSPECTIVE STUDY OF TOTAL NEOADJUVANT THERAPY FOR RECTAL CANCER | personal data/biological material | monocentric | Siebenhüner | Department of Gastrointestinal Oncology |
KHO Hirslanden Zürich AG, Zürich |
Kantonale Ethikkommission Zürich | 09.02.2024 | |||||||
| 2023-01510 | A Prospective, Post-marketing, non-interventional study of RISankizumab evaluating real-world clinical Effectiveness in Crohn’s disease (APPRISE) | non clinical, involving persons | multicentric | A | Prof. Dr. med. Frank Seibold | AbbVie AG |
Intesto Bern, Bern Insel Gruppe AG, Bern Centre Crohn et Colite Gastroentérologie La Tour, Hôpital d <...> roentérologie Beaulieu SA, Lausanne Gastrozentrum Hirslanden More ... |
Kantonale Ethikkommission Bern | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonal More ... | 03.01.2024 | |||||
| 2023-01489 | CAAA617D12302: An International, Prospective, Open-label, Multi-center, Randomized Phase III Study comparing lutetium (177Lu) vipivotide tetraxetan (AAA617) versus Observation to delay castration or d More ... | clinical trial | drugs | phase 3 | multicentric | B | PD Dr. med. Janusch Blautzik | Novartis Pharma Schweiz AG |
Hirslanden Klinik St. Anna, Luzern Hôpitaux universitaire de Genève, Geneva Stadtspital Zürich,, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 22.11.2023 | |||
| 2023-01421 | PREcooPera:A Window-of-Opportunity trial of giredestrant +/- triptorelin vs. anastrozole + triptorelin in premenopausal patients with ER-positive/HER2-negative early breast cancer | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Peter Dubsky | ETOP IBCSG Partner foundation |
Hirslanden Klinik St. Anna, Luzern Kantonsspital Baden, Department of Gynecology, Baden Brustzentrum Basel Bethesda Spital, Basel Spital Thurgau, Frauenfeld Instituto Oncologico della Swizzera Italian More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 09.10.2023 | |||
| 2023-01077 | DRAGON 2 - An international multicentre randomised controlled trial to compare combined Portal and Hepatic Vein Embolization (PVE/HVE) with PVE alone. | clinical trial | other clinical trials | multicentric | B | Prof. Dr. med. Stefan Breitenstein | Maastricht University, School for Oncology and Reproduction |
Kantonsspital Winterthur, Klinik für Viszeral- und Thoraxchirurgie, Winterthur St. Claraspital AG, Basel Universitätsspital Basel, Basel Hirslanden Klinik St. Anna, Luzern Klinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 09.01.2024 | ||||
| 2023-00928 |
A PHASE 3, RANDOMIZED, OPEN-LABEL, MULTICENTER STUDY OF ARV-471 (PF-07850327) PLUS PALBOCICLIB VERSUS LETROZOLE PLUS PALBOCICLIB FOR THE TREATMENT OF PARTICIPANTS WITH ESTROGEN RECEPTOR-POSITIVE, H More ... |
clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Razvan Andrei Popescu | Pfizer Inc. |
Tumor Zentrum Aarau Hirslanden, Aarau CHUV (Centre Hospitalier Universitaire Vaudois), Lausanne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.08.2023 | |||
| 2023-00749 | Prevalence of PD-L1 expression in gastric and GEJ cancer patients in Switzerland | personal data/biological material | multicentric | Dr. Alexander Siebenhüner | MSD Merck Sharp & Dohme AG, |
Hirslanden Zürich AG, Zürich Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 24.11.2023 | ||||||
| 2023-00676 |
Regulatory T-cells as tumor-promoting cellular partners and potential therapeutic targets in diffuse large B-cell lymphoma. |
non clinical, involving persons | multicentric | A | Prof. Dr. Frank Stenner | University Hospital Basel |
University Hospital Basel, Basel Klinik für Hämatologie und Onkologie Hirslanden Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 07.08.2023 | |||||
| 2023-00623 | Invasive Group A Streptococcus (iGAS) infection in adult population in Switzerland. A multicenter retrospective analysis | personal data/biological material | multicentric | Pr Jacques Schrenzel | HUG |
HUG, Geneva Institut for Infectious Diseases, Bern Hirslanden Klinik St Anna, Luzern University hospital of Basel, Basel HUG, GENEVA Cantonal Hospital of St Gallen, St Gallen Spital Thurgau AG, Thurga More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 04.12.2023 | ||||||
| 2023-00541 | Forecast of functional outcome and impact of anti factor Xa-levels in patients with intracerebral haemorrhage related to direct factor Xa inhibitors – a multi-center cohort study (FIRE-Xa) | non clinical, involving persons | multicentric | A | Prof. Dr. med. David Seiffge | Inselspital Bern |
Inselspital Bern, Bern Universitätsspital Basel, Basel Kantonsspital St. Gallen, St. Gallen Universitätsspital Zürich, Zürich Klinik Hirslanden Zürich, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 10.08.2023 | |||||
| 2023-00398 |
SAKK_LuCa_2 Retrospective and prospective registry of patients with metastatic NSCLC harboring typical and atypical EGFR mutations |
personal data/biological material | multicentric | Dr. med. Sabine Schmid | SAKK |
Inselspital Bern, Bern Kantonsspital Aarau, Aarau Tumor Zentrum Aarau Hirslanden Medical Center, Aarau Kantonsspital Baden, Baden, Brugg, Muri St. Claraspital, Basel Luzerner Kantonsspital, Luzern Uni More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 07.06.2023 | ||||||
| 2023-00313 | Long-Term outcomes of minimally invasive aortic valve replacement performed through a right anterior mini-thoracotomy | personal data/biological material | monocentric | PD Dr. Diana Reser | Witellikerstrasse 40 |
Herzklinik Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 10.08.2023 | |||||||
| 2023-00253 | Empagliflozin functional capacity - Non-Interventional Study Emp-Activity | non clinical, involving persons | multicentric | A | Prof. Dr. med. Matthias Hermann | Boehringer Ingelheim (Schweiz) GmbH |
Universitätsspital Zürich, Zürich Spitalzentrum Biel, Biel Spital Thun, Thun Spital Sonnenhof, Bern <...> l, Waltenschwil Spital Lachen, Lachen Herzzentrum Hirslanden More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 25.04.2023 | |||||