| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-00247 | Early Integration of Palliative Care in the Treatment of Women with Advanced Breast or Gynecological Cancer | non clinical, involving persons | monocentric | A | Dr. med. Esther Birindelli | University Hospital Zurich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 04.04.2025 | ||||||
| 2024-00246 | CT-guided Lung Biopsy Risk Optimization Method - Effect of Fluid Application in the Pleural Cavity and the Gravitational Effect of Pleural Pressure (BROM-I) | clinical trial | other clinical trials | monocentric | B | Dr. med. Michael P. Brönnimann | Insel Gruppe AG |
Insel Gruppe AG, Department of Diagnostic, Interventional and Pediatric Radiology, Bern |
Kantonale Ethikkommission Bern | 15.04.2024 | |||||
| 2024-00245 | Neonatal health in Lausanne then and now | personal data/biological material | multicentric | Prof. Dr. phil. Kaspar Staub | University of Zurich |
Institute of Evolutionary Medicine, University of Zurich, Zurich University Hospital Lausanne Switzerland, Lausanne |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.09.2024 | ||||||
| 2024-00243 | Real-world experience of Faricimab (Vabysmo) treatment for macular pathology in Switzerland | personal data/biological material | monocentric | PD. Dr. med. Martin K. Schmid | Luzerner Kantonsspital |
Augenklinik Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.03.2024 | |||||||
| 2024-00242 | Exploring systemic manifestation of cutaneous T-cell lymphoma | non clinical, involving persons | monocentric | A | Dr. med. Dr. sc. med. Egle Ramelyte | University Hospital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 17.05.2024 | ||||||
| 2024-00241 | CRISPR-Cas9 screening in colorectal cancer organoids | personal data/biological material | monocentric | Dr. Esposito Roberta | Medical Oncology Department, Inselspital |
Department for BioMedical Research, University of Bern; Medical Oncology, Inselspital, Bern |
Kantonale Ethikkommission Bern | 18.07.2024 | |||||||
| 2024-00239 | Retrospective analysis of clinical and paraclinical parameters from patients with multiple sclerosis and related disorders | personal data/biological material | monocentric | Prof. Dr. Patrick Roth | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 05.07.2024 | |||||||
| 2024-00238 | Inspiratory effort during assisted ventilation: what is normal? | personal data/biological material | multicentric | Francesca Porta | Kantonspital Graubünden |
Kantonspital Graubünden, Chur Ospedale Civico di Lugano, Lugano |
Kantonale Ethikkommission Zürich | Comitato etico cantonale Ticino | 26.03.2024 | ||||||
| 2024-00237 | The Effect of Acute High Altitude Exposure on Rescuer Performance and Patient Care | clinical trial | other clinical trials | monocentric | B | Prof. Dr. med. Jürgen Knapp | Klinik für Anästhesiologie und Schmerztherapie, Universitätsspital Bern |
Klinik für Anästhesiologie und Schmerztherapie, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 08.07.2024 | Study has ended | ||||
| 2024-00236 | Patient severity based on the NACA Score in Polytrauma: an observational retrospective study | personal data/biological material | monocentric | Prof Dr. med Christian Candrian | EOC |
EOC, Lugano |
Comitato etico cantonale Ticino | 15.04.2024 | |||||||
| 2024-00235 | Risk prediction in soft tissue sarcoma using Artificial Intelligence. A retrospective, multicentre study. | personal data/biological material | monocentric | Dr.med. Maria Anna Smolle | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 18.10.2024 | |||||||
| 2024-00234 | CTQJ230A12203 - A randomized double-blind, placebo-controlled, multi-center trial assessing the impact of lipoprotein(a) lowering with pelacarsen (TQJ230) on the progression of calcific aortic valve s More ... | clinical trial | drugs | phase 2 | multicentric | C | Dr. med. Jonathan Michel | Novartis Pharma Schweiz AG |
Universitätsspital Zürich, Zürich Universitätsspital Basel, Basel HUG, Geneve EOC, Lugano CHUV, Lausanne |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de la recherche Genève (CCER), Comitat More ... | 19.04.2024 | |||
| 2024-00233 | A superiority randomized controlled study on the efficacy of radiofrequency for the treatment of women patients with overactive bladder syndrome | clinical trial | other clinical trials | monocentric | B | PD Dr. med. Andrea Braga | Dept. Obstetrics and Gynaecology, EOC - Beata Vergine Hospital |
Dept. Obstetrics and Gynaecology, EOC - Beata Vergine Hospital, Mendrisio |
Comitato etico cantonale Ticino | 26.08.2024 | |||||
| 2024-00231 | Ticin regIstry for caTheter-based treAtments iN patIents with acute pUlmonary eMbolism | non clinical, involving persons | monocentric | A | Prof Marco Valgimigli | Cardiocentro Ticino Institute, EOC |
Cardiocentro Ticino Institute, EOC, Lugano, Lugano |
Comitato etico cantonale Ticino | 14.05.2024 | ||||||
| 2024-00230 | MK-2870-019: A Phase 3 Randomized Open-Label Study of Adjuvant Pembrolizumab With or Without MK-2870 in Participants With Resectable Stage II to IIIB (N2) NSCLC not Achieving pCR After Receiving Neoad More ... | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med. Michael Mark | Merck Sharp & Dohme LLC |
Kantonsspital Graubünden, Chur Spital Thurgau AG, Thurgau HFR hôpital fribourgeois, Fribourg Centre hospitalier universitaire vaudois (CHUV), Lausanne |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.04.2024 | |||
| 2024-00229 | Biomechanical Evaluation of Various Refixation Techniques Following Extended Trochanteric Osteotomy and Trochanteric Fractures in a Cadaver Model | deceased persons | monocentric | Prof. Dr. med. Patrick Zingg | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 12.04.2024 | |||||||
| 2024-00228 | TRINITY – Use of commercial human milk samples for in-vitro assays | personal data/biological material | monocentric | Lucile Yart | La Société |
La Société des Produits Nestlé, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.12.2024 | |||||||
| 2024-00225 | Initial experience with Simultaneous Pancreas- and Kidney Transplantations from Donors after Circulatory Death in Switzerland and review of the current literature | personal data/biological material | monocentric | Dr. med. Fabian Rössler | Department of Surgery and Transplantation, University Hospital of Zürich |
University Hospital of Zürich, Zürich |
Kantonale Ethikkommission Zürich | 26.03.2024 | |||||||
| 2024-00224 | One year results and comparison of two double mobility prostheses for trapeziometacarpal arthritis | personal data/biological material | monocentric | Sebastian Hediger | Kantonsspital Frauenfeld |
Kantonsspital Frauenfeld, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 08.02.2024 | |||||||
| 2024-00223 |
Efficacy of Transversus Thoracic Muscle Plane Block in Patients undergoing Cardiac Surgery A randomized controlled, double blind trial |
clinical trial | other clinical trials | monocentric | A | PD Dr Sina Grape | Hôpital du Valais |
Service d'Anesthésiologie, Centre Hospitalier du Valais Romand, Sion |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.04.2024 | Study has ended | ||||