| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-D0055 | Prospective evaluation of the Laryngeal Mask Singularity® in adult patients with or without neuromuscular blockade under clinical conditions | clinical trial | medical devices | monocentric | A1 | Prof. Dr. Alexander Dullenkopf | Spital Thurgau Frauenfeld |
Spital Thurgau Frauenfeld, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 12.06.2025 | |||||
| 2025-D0048 | A Single-Center, First-in-Human, Randomized, Controlled, Feasibility Study of a New Device for the Real-Time Continuous Monitoring of the Injection Pressure of Local Anesthetic in Subjects Undergoing More ... | clinical trial | medical devices | monocentric | C2 | Dr. med. Roberto Dossi | Service of Anesthesia, Ospedale Regionale di Bellinzona e Valli, EOC |
Ospedale Regionale di Bellinzona e Valli, EOC, Bellinzona |
Comitato etico cantonale Ticino | 02.06.2025 | |||||
| 2025-D0028 | Selective Pulmonary-artery Intervention to Reduce Acute Right-heart tEnsion-II. The SPIRARE II Study | clinical trial | medical devices | monocentric | C2 | Prof. Felix Mahfoud | Neptune Medical Inc. |
Department of Cardiology, University Heart Center Basel, University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.05.2025 | |||||
| 2025-D0025 | Comparison of 16F versus 24F chest drain after thoracoscopic lobectomy and/or segmentectomy: a monocentre prospective randomized controlled trial. | clinical trial | medical devices | monocentric | A1 | Dr. med. Makhmudbek Mallaev | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.04.2025 | |||||
| 2025-D0022 |
Retrospective clinical study to investigate the longevity of long-term single tooth restorations from IPS e.max CAD and Press |
clinical trial | medical devices | monocentric | A1 | Dr. med. dent. Lukas Enggist | Ivoclar Vivadent AG |
Ivoclar Vivadent AG, Schaan |
Kantonale Ethikkommission Zürich | 20.05.2025 | |||||
| 2025-D0016 | Randomized clinical trial investigating efficacy of birth mobility on birth outcomes in primiparous women. | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Leonhard Schäffer | Vibwife AG |
Kantonsspital Baden, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.04.2025 | |||||
| 2025-D0014 | Therapy response assessment of ultra-low dose long-axial field-of-view PET/CT in lymphoma patients: a single-center non-inferiority study | clinical trial | medical devices | monocentric | A2 | Dr. med. Clemens Mingels | Inselspital, Universitätsspital Bern Universitätsklinik für Nuklearmedizin |
Inselspital, Universitätsspital Bern Universitätsklinik für Nuklearmedizin, Bern |
Kantonale Ethikkommission Bern | 05.05.2025 | |||||
| 2025-D0010 | A post-market, interventional, confirmative clinical investigation to evaluate the performance and the safety of “LMW - CL - HA – FACE/BODY” used as intended for the restoration of the physiological v More ... | clinical trial | medical devices | monocentric | A2 | Dr. med. Corrado Parodi | Rose Pharma SA |
Ospedale Regionale di Lugano, Viganello |
Comitato etico cantonale Ticino | 25.03.2025 | |||||
| 2025-D0008 |
BIOTRONIK – A Prospective Multicenter Single-Arm Study to Assess the Safety and Effectiveness of the Orsiro Mission 48- mm Sirolimus-Eluting Coronary Stent System for the Treatment of Subjects with A More ... |
clinical trial | medical devices | monocentric | C2 | Prof. Dr. med.. Gregor Leibundgut | BIOTRONIK AG |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.03.2025 | |||||
| 2025-D0007 | Randomized controlled trial comparing closed face masks vs surface guided radiation therapy for head and neck radiotherapy (NoMask Study) | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Panagiotis Balermpas | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 15.04.2025 | |||||
| 2025-D0005 | Intra-individual comparison of PET scans of the Biograph Vision 600 with the new Biograph Vision.X PET/CT | clinical trial | medical devices | monocentric | A1 | Pr Valentina Garibotto | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 08.04.2025 | |||||
| 2025-D0004 | Safety and feasibility of ultrasound-assisted non-invasive measurement of compressibility of the thyroid gland in patients scheduled for surgical removal | clinical trial | medical devices | monocentric | C2 | PD Dr. med. Urs Borner | Insel Gruppe |
Insel Gruppe, Bern |
Kantonale Ethikkommission Bern | 28.05.2025 | |||||
| 2025-D0003 | Development of Artificial Intelligence algorithms from respiratory sounds recorded with the Pneumoscope in children and adolescents with wheezing disorders. | clinical trial | medical devices | monocentric | C2 | Isabelle Ruchonnet-Métrailler | Geneva University Hospitals |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 05.06.2025 | yes | ||||
| 2025-D0001 | Immediate loading of immediate single implants with a definitive crown in premolar regions: A prospective single-arm clinical trial | clinical trial | medical devices | monocentric | A1 | Dr. Med. Dent. Duygu Karasan | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 07.05.2025 | |||||
| 2025-01199 | Can the implementation of High Resolution Anoscopy (HRAn) in the standard follow-up after Anal Carcinoma Treatment reduce the recurrence rate? | personal data/biological material | monocentric | Dr. med. Susanne Bock |
HOCH Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 12.06.2025 | ||||||||
| 2025-01175 | Treatment of severe aortic stenosis with transfemoral TAVI with or without coronary angiogram during diagnostic work-up | clinical trial | other clinical trials | monocentric | A | Dr. Thomas Nestelberger | Rede Optimus Hospitalar AG |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.06.2025 | |||||
| 2025-01169 | REVIVE Zug: Impact of a cantonal first responder system on ROSC rates and incidence of shockable rhythms in out-of-hospital cardiac arrest (OHCA). | personal data/biological material | monocentric | Felix Brinkmann | Rettungsdienst des Kantons Zug |
Rettungsdienst des Kantons Zug, Zug |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.06.2025 | |||||||
| 2025-01156 | Arterial to central-venuous CO2-gap as prognostic parameter in critically ill patients | personal data/biological material | monocentric | Prof. Dr. Alexander Dullenkopf | Spital Thurgau Frauenfeld |
Spital Thurgau Frauenfeld, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 19.06.2025 | |||||||
| 2025-01123 | Single versus multiple segmentectomy for NSCLC | personal data/biological material | monocentric | Prof. Dr. med Michel Gonzalez | CHUV - Chirurgie Thoracique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 05.06.2025 | |||||||
| 2025-01098 |
Predictors of Recovery and Psychological Well-Being in Outpatient Cardiac Rehabilitation: A Multidimensional Approach |
personal data/biological material | monocentric | PD Dr. med. Dagmar Astrid Schmid | Klinik für Psychosomatik und Konsiliarpsychiatrie HOCH |
Klinik für Psychosomatik und Konsiliarpsychiatrie HOCH, St Gallen |
Ethikkommission Ostschweiz (EKOS) | 05.06.2025 | |||||||