| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-00014 | Stromal cell composition and inflammation-induced remodeling in chronic rhinosinusitis with polyps. | personal data/biological material | monocentric | Prof. Burkhard Ludewig | Medical Research Center HOCH Health Ostschweiz |
Medical Research Center HOCH Health Ostschweiz, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 15.01.2026 | |||||||
| 2026-00012 | Detecting Risk Before Decline: A Comparative Study of MNA-SF and NRS 2002 in Predicting Malnutrition Outcomes in Geriatric Inpatients. The NOURISH study | personal data/biological material | monocentric | Professor Patrizia D’Amelio | CHUV - Gériatrie |
Centre Hospitalier Universitaire Vaudois, CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 15.01.2026 | |||||||
| 2026-00003 | Outcome in giant cell arteritis according to disease manifestation and treatment | personal data/biological material | monocentric | Schmid Elias | Department of Rheumatology HOCH |
University St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 08.01.2026 | |||||||
| 2025-D0083 | Auricular Vagal Neuromodulation Therapy (AVNT) with Nurosym for Preventing Postoperative Atrial Fibrillation, Decreasing Inflammatory Responses, and Improving Patient Recovery following CABG – a Rando More ... | clinical trial | medical devices | monocentric | C1 | Professor Christoph Huber | Hôpitaux Universitaires de Genève (HUG) |
Hôpitaux Universitaires de Genève (HUG), Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.12.2025 | |||||
| 2025-D0081 | Non-pharmacological Enhancement of Deep Sleep with Auditory Stimulation versus Sham in People with Parkinson’s Disease and Mild Cognitive Impairment Receiving Cognitive Training: A Double-blind Random More ... | clinical trial | medical devices | monocentric | C2 | Dr. med. Simon Schreiner | University Hospital Zurich |
Department of Neurology, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 18.12.2025 | |||||
| 2025-D0077 |
Clinical Safety and effectiveness of Straumann Dynamic Navigation System (Falcon): A prospective multicenter and multinational Clinical Investigation CR 2023_02 Straumann Falcon |
clinical trial | medical devices | monocentric | A2 | Prof. Sebastian Kuehl | Institut Straumann AG |
Universitäres Zentrum für Zahnmedizin Basel – UZB Klinik für Oralchirurgie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.10.2025 | |||||
| 2025-D0075 | Evaluation of a software to predict the postoperative component position in total hip arthroplasty (THA): Accuracy of predictions and impact on interoperative placement in a single centre | clinical trial | medical devices | monocentric | A1 | Prof. Dr. Marcel Jakob | crossklinik AG |
crossklinik, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.09.2025 | |||||
| 2025-D0073 | Procedural Comparative Evaluation of Pulmonary Vein Isolation Using the FARAWAVE Nav PFA Catheter Without Pre-Ablation Computer Tomography (CT) vs. Conventional Farapulse With Pre-Ablation CT: A singl More ... | clinical trial | medical devices | monocentric | A1 | Dr. Med. Marco Bergonti | Istituto Cardiocentro Ticino - Ente Ospedaliero Cantonale |
Istituto Cardiocentro Ticino - Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 17.09.2025 | |||||
| 2025-D0071 | Blink restoration in patients with facial nerve palsy V2 | clinical trial | medical devices | monocentric | C2 | Dr. med. Anthia Papazoglou | Augenklinik Kantonsspital Aarau |
Augenklinik Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.10.2025 | |||||
| 2025-D0069 |
Role of Slow Waves in the Progression of Neurodegeneration in Isolated REM Sleep Behavior Disorder |
clinical trial | medical devices | monocentric | C2 | Prof. Dr. med. Andreas Luft | University of Zurich |
University Hospital Zurich, Department of Neurology, Zurich |
Kantonale Ethikkommission Zürich | 02.12.2025 | |||||
| 2025-D0066 | Randomized trial of ELEVATEd cardiac pacing rate for personalized treatment of Heart Failure with preserved Ejection Fraction (ELEVATE-HFpEF) | clinical trial | medical devices | monocentric | C1 | Prof. Dr. Haran Burri | Medtronic Bakken Research Center |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 23.12.2025 | |||||
| 2025-D0065 | OBPM_HARMONY: Physiological data recording over 24 hours using the continual optical Hilo Blood Pressure monitor and an Ambulatory Blood Pressure Monitor: a single-center, prospective clinical study. | clinical trial | medical devices | monocentric | A1 | Pr Grégoire WUERZNER | Aktiia SA |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.11.2025 | |||||
| 2025-D0063 | Artiqo_RSA: Migration of the cemented A2® Type B prosthesis: a radio stereometric analysis | clinical trial | medical devices | monocentric | A1 | Prof. Karl Stoffel | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.11.2025 | |||||
| 2025-D0061 | Microvascular Obstruction diagnosis using the CoFI™ System Assessment - II | clinical trial | medical devices | monocentric | C2 | Dr Antonio Landi | CorFlow |
Istituto Cardiocentro Ticino, Lugano |
Comitato etico cantonale Ticino | 10.12.2025 | |||||
| 2025-D0060 | Feasibility of unsupervised therapy after neurological or orthopaedical injury in the home setting with a hand rehabilitation device (ReHandyBot) and an assistive smartphone application (RehabCoach): More ... | clinical trial | medical devices | monocentric | C2 | Dr. Bertrand Léger | Rehabilitation Engineering Lab, ETH Zurich |
SUVA clinics, Bellikon |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.10.2025 | |||||
| 2025-D0058 | The Susatu PHOENIX Trial ‘SPOT’ - A prospective, single-center, interventional trial to determine the clinical performance of a novel osteosynthesis material detector in comparison to standard clinica More ... | clinical trial | medical devices | monocentric | C2 | PD Dr. med. Michael Schär | susatu GmbH |
Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 10.11.2025 | |||||
| 2025-D0056 | Early feasibility evaluation of the UniBE hybrid closed-loop insulin delivery system in Type 1 Diabetes: UBLoop - Genesis | clinical trial | medical devices | monocentric | C2 | Prof. Dr. med. Markus Laimer | University of Bern |
Universitätsklinik für Diabetologie, Endokrinologie, Ernährungsmedizin & Metabolismus (UDEM), Inselspital, Universitätsspital, CH-3010 Bern |
Kantonale Ethikkommission Bern | 10.11.2025 | |||||
| 2025-D0055 | Prospective evaluation of the Laryngeal Mask Singularity® in adult patients with or without neuromuscular blockade under clinical conditions | clinical trial | medical devices | monocentric | A1 | Prof. Dr. Alexander Dullenkopf | Spital Thurgau Frauenfeld |
Spital Thurgau Frauenfeld, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 12.06.2025 | |||||
| 2025-D0054 | Exploration of the functional effect of different hearing aid noise reduction algorithms in an ecologically valid conversational situation | clinical trial | medical devices | monocentric | A1 | Josephine Hollenbach | Sonova AG |
Sonova AG, Stäfa |
Kantonale Ethikkommission Zürich | 05.09.2025 | Study has ended | ||||
| 2025-D0053 | An international, multi-centre observational study to evaluate safety, performance, and clinical benefit of the BeFlow Iliac Covered Stent System | clinical trial | medical devices | monocentric | A1 | Dr Med Maria Antonella Ruffino, MD, EBIR | Bentley InnoMed GmbH |
Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 01.10.2025 | |||||