BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2023-D0113 PEERLESS II - Randomized Controlled Trial of FlowTriever vs. Anticoagulation alone in Pulmonary Embolism clinical trial medical devices multicentric A1 Dr. Gregor Leibundgut Inari Medical Europe GmbH Universitätsspital Basel, Basel
Inselspital Bern, Bern
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern 25.01.2024
2023-D0103 Safety and performance of the Biphasic Plate Distal Femur: A multicenter case series clinical trial medical devices multicentric A1 Dr.Med Christian Michelitsch 41medical AG Kantonsspital Graubunden, Chur
University Hospital Basel, Department of Orthopaedics and Traumatology
Unive
Universitätsspital Zürich, Rämistrasse 100
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ 23.01.2024
2023-D0074 Platelet count and function after usage of two different cell saver devices during cardiac surgery: a randomized controlled multi-center equivalence trial. clinical trial medical devices multicentric A1 Dr. med. / Fabio/ Barattiero Inselspital Bern, University of Bern Inselspital Bern, Bern
Hôpitaux Universitaires Genève, HUG, Rue Gabrielle-Perret-Gentil 4
CH-1205 Genève
Universiy Hospital Zurich, Institut für Anästhesiologie Rämistrasse 100,
809
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) 06.11.2023
2023-D0063 PACIFIC-8: A Phase III, Randomised, Double-blind, Placebo-controlled,
Multicentre, International Study of Durvalumab plus
Domvanalimab (AB154) in Participants with Locally Advanced
(Stage III), Unr More ...
clinical trial combination drugs/devices multicentric C1 Dr. med. David König AstraZeneca AB Universitätsspital Basel, Basel
Inselspital, Universitätsspital Bern, Bern
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern 02.11.2023
2023-D0055 Safety and normative data with neos™, in healthy volunteers, children and patient populations with ophthalmological or neurological disease clinical trial medical devices multicentric A1 MD, PhD, Tatiana BREMOVA-ERTL machineMD AG Neurology Inselspital Bern, Bern
Onovis Augenpraxis, Bern
machineMD AG, Weyermannsstrasse 36
Kantonale Ethikkommission Bern Kantonale Ethikkommission Bern 27.09.2023 yes
2023-D0052 CARITY-P: A targeted approach to ensuring CARe and ActivITY persistence in mid- to older-age persons during and after cardiac rehabilitation following a cardiovascular event or intervention clinical trial medical devices multicentric C2 Prof. Dr. med. / Matthias / Hermann Carity AG Universitätsspital Zürich, Zurich
Luzerner Kantonsspital, Herzzentrum
Spitalstrasse
Kantonsspital St. Gallen, Rorschacher Strasse 95
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Ethikkommission Nordwest- und Zentralschweiz EKNZ 10.10.2023
2023-D0043 Clinical Performance Study Protocol for PD-L1 IHC 22C3 pharmDx on Non-Squamous Non-Small Cell Lung Cancer Specimens.

Supplement to Clinical Trial Protocol DS1062-A-U303.
clinical trial in vitro diagnostic medical devices multicentric C1 Dr. med. / Bettina / Seifert Daiichi Sankyo Inc. KSBL Baselland, Liestal
Spital STS AG, Thun
KSSG, Rorschacher Strasse 95
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS) 24.08.2023
2023-D0041 DEFIANCE - Randomized controlled trial of ClotTriever system versus anticoagulation in deep vein thrombosis clinical trial medical devices multicentric A2 Dr. Marc Schindewolf Inari Medical Europe GmbH Inselspital Bern, Bern
Luzerner Kantonsspital, Spitalstrasse
CH-6000 Luzern 16
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ 08.09.2023
2023-D0029 Robotic minimAlly invaSive inguinAl Hernia rEpAir with Dexter® clinical trial medical devices multicentric A1 Prof. Dr. med. Stefan Breitenstein Distalmotion SA Kantonsspital Winterthur, Winterthur
Spital Tiefenau, Bern
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern 02.05.2023 Study has ended
2023-D0026 Renal Denervation in Patients with Recurrent Atrial Fibrillation after Successful Pulmonary Vein Isolation (REDE-AF): a national, multi-centre, prospective, single-arm, pre-to-post treatment, medical- More ... clinical trial medical devices multicentric C1 Prof. Dr. med. Laurent Roten Insel Gruppe AG Insel Gruppe AG, Bern
Universitätsspital Basel, Petergraben 4
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ 05.06.2023
2023-D0024 Diagnostic Protocol for VENTANA FGFR2b (FPR2-D) RxDx Assay
in Amgen Study 20210098
clinical trial in vitro diagnostic medical devices multicentric C2 Dr. Martin Dave Berger Ventana Medical Systems, Inc. Inselspital, University Hospital Bern, Bern
Universitätsspital Basel, Medical Oncology
Petersgraben 4
Hôpitaux universitaires de Genève, Service d'oncologie
Rue Gabrielle-Perret-Gentil
University More ...
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER) 10.05.2023
2023-D0023 Feasibility and efficacy of a transdiagnostic app-based psychological aftercare intervention clinical trial medical devices multicentric A1 Dr. Klaus Bader Universitäre Psychiatrische Kliniken Basel Universitäre Psychiatrische Kliniken, Basel
Psychiatrische Dienste Aargau, Klinik für Psychiatrie und Psychotherapie
Königs
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ 04.05.2023
2023-D0016 A Combination of Low-Energy Ultrasound, Electrical and Magnetic Field
Stimulation in Patients with Therapy-Resistant Myofascial Pain Syndrome:
A Randomized, Controlled, Double-Blind Multi-Center Stu More ...
clinical trial medical devices multicentric C2 PD Dr. med. Christophe Perruchoud SOBET AG Hôpital de La Tour, 1217 Meyrin
Salem-Spital Bern, Bern
Schmerzklinik Zürich, Wallisellenstr. 301a
Commission Cantonale d'éthique de la recherche Genève (CCER) Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich 17.04.2023
2023-D0011 Multicentric prospective clinical study to evaluate the Aktiia Optical Blood Pressure Monitoring (OBPM) device compared to standard Home Blood Pressure Monitoring (HBPM) in hypertensive patients when More ... clinical trial medical devices multicentric A1 Dr Grégoire WUERZNER AKTIIA SA CHUV, Lausanne
HUG, Rue Gabrielle-Perret-Gentil 4,
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Commission Cantonale d'éthique de la recherche Genève (CCER) 26.05.2023
2023-D0006 MO42720 - INTERVENTIONAL PLATFORM STUDY INVESTIGATING THE IMPACT OF DIGITAL HEALTH SOLUTIONS ON HEALTH OUTCOMES AND HEALTH-CARE RESOURCE UTILIZATION IN PARTICIPANTS RECEIVING SYSTEMIC TREATMENT IN CLI More ... clinical trial medical devices multicentric A1 Dr. med. Hasna Bouchaab Roche Pharma (Schweiz) AG Centre hospitalier universitaire vaudois (CHUV), Lausanne
Tumor Zentrum Aarau, Rain 34
Hôpitaux universitaires de Genève, Rue Gabrielle-Perret-Gentil 4
Stadtspital Zürich Triemli, Med. Onkologie und H More ...
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER) 09.05.2023
2023-02343 Adjuvant immunotherapy with anti-PD-1 monoclonal antibody Pembrolizumab (MK-3475) versus placebo after complete resection of high-risk Stage III melanoma: A randomized, double- blind Phase 3 trial of More ... clinical trial drugs phase 3 multicentric C Prof. Dr. Reinhard Merck Sharp & Dohme LLC, a Subsidiary of Merck & Co. Inc Dummer, Zürich
Unité d'Oncodermatologie, Service de Dermatologie, Hôpitaux Universitaire de Genève, 1211 GENEVE 14
Kantonsspital St. Gallen Klinik für Onkologie/Hämatologie, 9007 St. Gallen
Kantonale Ethikkommission Zürich Ethikkommission Ostschweiz (EKOS), Commission Cantonale d'éthique de la recherche Genève (CCER) 23.01.2024
2023-02342 Immunotherapy with or without upfront stereotactic radiosurgery in
patients with Non-Small Cell Lung Cancer with asymptomatic brain
metastases: A retrospective comparison
personal data/biological material multicentric Dr. Sabine Schmid Klinik für medizinische Onkologie, Inselspital Bern Klinik für Medizinische Onkologie, Inselspital Bern, Bern
Medizinische Onkologie Kantonsspital Baden, Baden
Medizinsiche Onkologie Kantonsspital Luzern, Luzern
Klinik für Onkologie, Kantonsspital Aara More ...
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... 27.02.2024
2023-02309 Phase 3, interventional, multicentre, open label, randomized study comparing rituximab plus zanubrutinib to rituximab monotherapy in previously untreated, symptomatic splenic marginal zone lymphoma (R More ... clinical trial drugs phase 3 multicentric C Dr. med. Maria Cristina Pirosa International Extranodal Lymphoma Study Group (IELSG) Oncology Institute of Southern Switzerland, Bellinzona
Inselspital / Universitätsspital, Bern
Comitato etico cantonale Ticino Kantonale Ethikkommission Bern 15.02.2024
2023-02304 Validity and Reliability of the 12-item Multiple Sclerosis Walking Scale (12-WS) in subjects with spinal
cord injury
clinical trial other clinical trials multicentric A PD Dr. med. Dr. sc. nat. Björn Zörner Universität Zürich Universität Zürich, Zürich
Schweizer Paraplegiker-Zentrum, Nottwil
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ 27.02.2024
2023-02245 Influence de la conscience corporelle sur l’évolution de la symptomatologie clinique chez les patients souffrant d’un trouble de la personnalité borderline et suivant une psychothérapie non clinical, involving persons multicentric A Pierre Simon Les Toises - Centre de Psychiatrie et Psychothérapie Les Toises - Centre de Psychiatrie et Psychothérapie, Montagny-près-Yverdon
Les Toises - Centre de Psychiatrie et Psychothérapie, Lausanne
Les Toises - Centre de Psychiatrie et Psychothérapie, Nyon
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 28.02.2024