| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-00187 | Laser interstitialthermaltherapy (LITT): eine multizentrische retrospektive Kohortenstudie | personal data/biological material | multicentric | Prof. Dr. med. Oliver Bozinov | HOCH |
HOCH Health Ostschweiz, St. Gallen HOCH Health Ostschweiz, St. Gallen USZ Universitäts Spital Zürich, Zürich |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 05.02.2026 | ||||||
| 2026-00042 | Estimation of the duration of inpatient stays for patients treated with 131Iodine | personal data/biological material | multicentric | Prof. Dr. med. Irene A. Burger | KSB |
KSB, Baden LUKS, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.01.2026 | ||||||
| 2025-D0096 | Prospective Post Market Clinical Follow-Up (PMCF) Study of the Zimmer® Trabecular Metal™ Total Ankle | clinical trial | medical devices | multicentric | A1 | Dr. med. Helen Anwander | Zimmer GmbH |
Inselspital-Stiftung, Bern Berner Fusszentrum, Bern |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 05.02.2015 | ||||
| 2025-D0086 | A Phase 3, Randomized, Double-blind, Add-on Study Evaluating the Safety and Efficacy of Navtemadlin Plus Ruxolitinib vs Placebo Plus Ruxolitinib in Patients with Myelofibrosis Who Have a Suboptimal Re More ... | clinical trial | in vitro diagnostic medical devices CDx | multicentric | C2 | Dr. med. Thomas Lehmann | Kartos Therapeutics, Inc. |
Cantonal Hospital Saint Gallen, St. Gallen Inselspital, University Hospital Bern, Bern University Hospital Basel, Klinik für Hämatologie Petersgraben 4 Ente Ospedaliero Cantonale, Institute for Oncol More ... |
Ethikkommission Ostschweiz (EKOS) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Com More ... | 16.10.2025 | ||||
| 2025-D0085 | Real-Time Intracardiac Echocardiography for Ventricular Arrhythmia Ablation: A Randomized Controlled Trial | clinical trial | medical devices | multicentric | A1 | Dr. med. Boldizsár Kovács | Insel Gruppe AG |
Inselspital Bern, Bern Universitätsspital Basel, Universitätsklinik für Kardiologie Petersgraben 4 |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.01.2026 | ||||
| 2025-D0078 | Robotic Assisted Right Colectomy with the DExter® Robotic Surgery System | clinical trial | medical devices | multicentric | A1 | Dr. med. Thomas Kinsbergen | Distalmotion SA |
Spital Langenthal, Langenthal FMI Spitäler (Interlaken), Unterseen Kantonsspital St Gallen, Rorschacher Strasse 95 9007 St.Gallen |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS) | 16.12.2025 | ||||
| 2025-D0068 | DESTINY-Endometrial01: An Open-Label, Sponsor-Blinded, Randomized, Controlled, Multicenter, Phase III Study of Trastuzumab Deruxtecan (T-DXd) Plus Rilvegostomig or Pembrolizumab vs Chemotherapy Plus P More ... | clinical trial | in vitro diagnostic medical devices CDx | multicentric | C2 | Dr. med. Marcus Vetter | AstraZeneca AB |
Kantonsspital Baselland, Liestal HOCH Health Ostschweiz, Kantonsspital St. Gallen Rorschacher Strasse 95 Universitätsspital Zürich, Frauenklinikstrasse 10 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 29.10.2025 | ||||
| 2025-D0067 | A Multi-center, Randomized-controlled, 12-month, split-mouth, Non-inferiority Clinical Trial to Compare the Safety and Performance of two different Curing Modes in the Direct Filling Therapy with a Fl More ... | clinical trial | medical devices | multicentric | C1 | Prof. Dr. med. dent. Klaus Neuhaus | Ivoclar Vivadent AG |
N|DENT ZAHNARZTPRAXIS, Herzogenbuchsee Zahnarztpraxis Chrüzhof, Kreuzstrasse 3b |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.10.2025 | yes | |||
| 2025-D0059 |
20230222 - Measurement of Samples with Tina-quant Lp(a) RxDx to Identify Participants with Elevated Lipoprotein(a) for Prevention of First Major Cardiovascular Events and A Double-blind, Random More ... |
clinical trial | in vitro diagnostic medical devices CDx | multicentric | C2 | PD Dr. med. Stefan Bilz | AMGEN |
HOCH Health Ostschweiz Kantonsspital St.Gallen Klinik für Endokrinologie, Diabetologie, Osteologie und Stoffwechselerkrankungen, St Gallen Inselspital Universitätsklinik für Kardiologie, Bern Luzern More ... |
Ethikkommission Ostschweiz (EKOS) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Com More ... | 17.07.2025 | ||||
| 2025-D0052 | Certified Comprehensive Eye-Movement Examination in Children with Attention Deficit Hyperactivity Disorder: An Objective, Reproducible and Quantitative Diagnosis in 15 Minutes? | clinical trial | medical devices | multicentric | A1 | Dr. med. Dr. sc. nat. Christine Schneider | Onovis Augenpraxis |
Kinderarztpraxis ADHS Diagnostik und Therapie bei Kindern und Jugendlichen, Bern Onovis Augenpraxis, Bern |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 03.09.2025 | yes | |||
| 2025-D0051 | MR45625: A PHASE IIIb, MULTICENTER, SINGLE-ARM STUDY ASSESSING THE EFFECTIVENESS, SAFETY AND PATIENT REPORTED OUTCOMES OF A 36-WEEK REFILL EXCHANGE REGIMEN FOR THE PORT DELIVERY SYSTEM WITH RANIBIZUMA More ... | clinical trial | combination drugs/devices | multicentric | C2 | Prof. Dr. med. Justus Garweg | F. Hoffmann-La Roche AG, Grenzacherstrasse 124, 4058 Basel |
Berner Augenklinik, Bern Pallas Kliniken Olten, Louis Giroud-Strasse 20/26 HOCH Health Ostschweiz, Kantonsspital St. Gallen Augenklinik Rorschacher |
Kantonale Ethikkommission Bern | Ethikkommission Ostschweiz (EKOS), Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.09.2025 | ||||
| 2025-D0045 | Neurorehabilitation of cognitive deficits in multiple sclerosis using an adaptive cognitive exergame: randomized, controlled, multi-center clinical trial | clinical trial | medical devices | multicentric | C2 | Prof. Arseny Sokolov | CHUV |
CHUV, Lausanne Inselspital Bern, Bern Ambulante Reha Triemli, Kliniken Valens, Birmensdorferstrasse 497 |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 02.09.2025 | ||||
| 2025-D0039 | BIOresorbable scaffold combined with drug-coated balloons for HYBRID percutaneous coronary intervention versus a conventional drug-eluting stent-based strategy in patients with long and diffuse corona More ... | clinical trial | medical devices | multicentric | A2 | Prof. Dr med. Gregor Leibundgut | Hôpitaux Universitaires de Genève |
Universitätsspital Basel, Klinik für Kardiologie, Basel Hôpitaux Universitaires de Genève, Service de Cardiologie Interventionnelle Rue Gabr |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission Cantonale d'éthique de la recherche Genève (CCER) | 30.07.2025 | ||||
| 2025-D0035 | WO45654 - A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Inavolisib Plus a CDK4/6 Inhibitor and Letrozole Versus Placebo Plus a CDK4 More ... | clinical trial | in vitro diagnostic medical devices CDx | multicentric | C1 | Prof. Dr. Christian Kurzeder | Roche Pharma (Schweiz) AG |
Universitätsspital Basel, Basel Kantonsspital Baden, KSB, Im Ergel 1 Luzerner Kantonsspital, Spitalstrasse Centre hospitalier universitaire vaudois; CHUV, Département d'oncologie Rue de Bugnon 46 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.07.2025 | ||||
| 2025-D0026 | Post-market clinical follow-up investigation to evaluate safety and effectiveness of Magic InBra™ breast pump in expressing and collecting milk from lactating women`s breast | clinical trial | medical devices | multicentric | A1 | Carola Eichmann | Medela AG |
Medela AG, Baar GIM Suisse AG, General-Wille-Strasse 10 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 29.04.2025 | ||||
| 2025-D0023 |
EARLY Antibiotics aDaptation in ventilator-Acquired-Pneumonia Treatment after Implementation of a Broad-Panel Respiratory Multiplex PCR test: A Multicenter Randomized Control Trial Conducted In Swiss More ... |
clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | A1 | Dr. Christophe Le Terrier | University Hospitals of Geneva |
Hôpitaux universitaire de Genève, Genève Hôpital cantonal du Tessin, Division of Intensive care CHUV, Dept. of Intensive Care Medicine BH-08-619 CHUV Hôpitaux du Valais, Avenue du Grand-Champsec 80 More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 05.08.2025 | ||||
| 2025-D0021 | Clinical Performance Study Protocol for Use of the VENTANA PD-L1 (SP263) CDx Assay: Evaluation of PD-L1 Expression Levels in Non-small Cell Lung Cancer Specimens from Phase III Study CA2241093 (Relati More ... | clinical trial | in vitro diagnostic medical devices CDx | multicentric | C2 | Dr Andreas Schmitt | Bristol-Myers Squibb Company |
University Hospital Basel, Basel Spital Thurgau, Kantonsspital Munsterlingen Spitalcampus 1 Ospedale Cantonale Bellinzona, Viale Officina 3 CHUV, Departement d'oncologie UNIL, Rue due Bugnon 46 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Ostschweiz (EKOS), Comitato etico cantonale Ticino | 02.07.2025 | ||||
| 2025-D0008 |
BIOTRONIK – A Prospective Multicenter Single-Arm Study to Assess the Safety and Effectiveness of the Orsiro Mission 48- mm Sirolimus-Eluting Coronary Stent System for the Treatment of Subjects with A More ... |
clinical trial | medical devices | multicentric | C2 | Prof. Dr. med.. Gregor Leibundgut | BIOTRONIK AG |
University Hospital Basel, Basel Istituto Cardiocentro Ticino, Via Tesserete 48 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Comitato etico cantonale Ticino | 17.03.2025 | ||||
| 2025-02484 | Transparietal Endoscopic Resection of Rectal Scars After Incomplete Resection of Neuroendocrine Tumors | personal data/biological material | multicentric | Doctor Sebastien Godat, PD, MER | CHUV - Gastroentérologie |
CHUV, Lausanne Inselspital, Bern Luzerner Kantonsspital LUKS, Luzern Hôpital Riviera Chablais, Rennaz |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.02.2026 | ||||||
| 2025-02468 | Long-Term Use of Guselkumab: Non-interventional Assessment of Real-world Outcomes LUNAR | non clinical, involving persons | multicentric | A | Prof. Dr. med. Emanuel Burri | Intesto Bern |
Kantonspital Baselland, Liestal Intesto Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 02.02.2026 | |||||