| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-D0054 | CLARITY-Gastric01 - A Phase III Multi-center, Open-label, Sponsor-blinded, Randomized Study of AZD0901 Monotherapy Compared with Investigator’s Choice of Therapy in Second- or Later-Line Adult Partici More ... | clinical trial | in vitro diagnostic medical devices | multicentric | C2 | Dr med Alexander Siebenhüner | AstraZeneca |
Klinik für Hämatologie und Onkologie Hirslanden Zürich AG , Witellikerstrasse 40, 8032 Zürich INSELSPITAL Universitätsspital Bern Universitätsklinik für medizinische Onkologie Klinische Forschungseinh More ... |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 27.08.2024 | ||||
| 2024-D0037 | The DEXTER-assisted non-emergent and acute cholecystectomy Study | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Stefan Breitenstein | Distalmotion SA |
Kantonsspital Winterthur, Winterthur Hirslanden Zurich, Chirurgisches Zentrum Zürich Witellikerstrasse 40 |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 14.06.2024 | ||||
| 2024-D0018 | A performance evaluation study for the testing of DNA extracted from tumor tissue samples, using the therascreen® KRAS RGQ PCR Kit, from participants with Non-Small Cell Lung Cancer in Lilly’s Clinica More ... | clinical trial | in vitro diagnostic medical devices | multicentric | A2 | Ulrich Richer | Qiagen Manchester Limited |
University Hospital of Zurich, Zürich Cantonal Hospital Winterhur, Brauerstrasse 15, Postfach 834 CH-8401 Winterhur |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 28.06.2024 | ||||
| 2024-D0011 | BIOTRONIK – Safety and Clinical Performance of the Drug Eluting Resorbable Coronary MAGnesium Scaffold System (Freesolve®) in the Treatment of Subjects with de Novo Lesions in Native Coronary Arteries More ... | clinical trial | medical devices | multicentric | A2 | PD Dr. med. | BIOTRONIK AG |
Juan Fernando, Iglesias Inselspital Bern, Bern University Hospital Basel, University Heart Center Petersgraben 4 Stadtspital Triemli, Klinik für Kardiologie Birmensdorferstrasse 497 Universitätsspit More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.05.2024 | ||||
| 2024-D0006 | Advancing Cath Lab Results with FFRangio® Coronary Physiology Assessment: The ALL-RISE Study | clinical trial | medical devices | multicentric | A1 | Dr. Juan Fernando Iglesias | CathWorks Inc. |
Unité de Cardiologie interventionnelle Service de Cardiologie Hôpitaux Universaires de Genève, Genève CHUV, Service de cardiologie, Unite de Cardiologie lnter |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.06.2024 | ||||
| 2024-D0002 | Clinical Performance Study Plan for FoundationOne® Liquid CDx as a Clinical Trial Assay in Clinical Trial GO42144 PLAN-00030, Version 04 | clinical trial | in vitro diagnostic medical devices | multicentric | C1 | Dr. med. et phil. nat. Simon Häfliger | Genentech, Inc. |
Inselspital Bern, Universitätsklinik für Medizinische Onkologie, Bern Hôpitaux Universitaires de Genève, Département d'Oncologie, Rue Gabrielle-Perret-Gentil 4 |
Kantonale Ethikkommission Bern | Commission Cantonale d'éthique de la recherche Genève (CCER) | 27.03.2024 | Study has ended | |||
| 2024-01740 | Enroll-HD: A Prospective Registry Study in a Global Huntington's Disease Cohort | non clinical, involving persons | multicentric | A | Prof. Michael Orth | SiloahAG - Neurozentrum |
Neurozentrum Siloah, Gümligen Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 30.10.2017 | yes | ||||
| 2024-01397 | Gait Reference Data: Evaluating gait pattern and body kinematics in both healthy individuals and populations with neurological conditions | non clinical, involving persons | multicentric | A | Dr. Chris Awai | Lake Lucerne Institute |
Lake Lucerne Institute, Vitznau Swiss Paraplegic Center, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.07.2024 | |||||
| 2024-01387 | Incidence and Risk Factors of Surgical Site Infections in Vascular Surgical Procedures in the Groin | personal data/biological material | multicentric | PD Dr. Edin Mujagic | Universitätsspital Basel |
Department of Vascular Surgery, University Hospital of Basel, Basel Vascular Surgery, Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.07.2024 | ||||||
| 2024-01358 | An open-label, multicenter, randomized Phase 2 study of the ATR inhibitor tuvusertib in combination with the PARP inhibitor niraparib or the ATM inhibitor lartesertib in participants with BRCA mutant More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Jens Huober | Merck Healthcare KGaA |
Kantonsspital St. Gallen, St. Gallen Kantonsspital Baselland, Liestal Spital Thurgau, Frauenfeld Ente Ospedaliero Cantonale ( EOC ) Istituto Oncologico della Svizzera Italiana (IOSI) Ospedale San Giov More ... |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 29.08.2024 | |||
| 2024-01254 | Investigation of bio-impedance sensing as a method for wearable non-invasive bladder volume measurements | non clinical, involving persons | multicentric | A | Prof. Dr. med. Jürgen Pannek | ETH Zürich |
Schweizer Paraplegiker-Zentrum, Nottwil ETH Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 21.08.2024 | |||||
| 2024-01209 | Impact of Repeated Infectious Events on Patient and Graft Outcome in ABO Incompatible Living Donor Kidney Transplantation: analysis of the STCS | personal data/biological material | multicentric | Prof. Daniel Sidler | Inselspital Bern |
Universitätsklinik für Nephrologie, Bern Department of Nephrology and Hypertension, Basel Department of Nephrology and Hypertension, Geneve Department of Nephrology and transplant medicine, Kantonspit More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 15.07.2024 | ||||||
| 2024-01205 | C4391022 / AN INTERVENTIONAL, OPEN-LABEL, RANDOMIZED, MULTICENTER PHASE 3 STUDY OF PF-07220060 PLUS FULVESTRANT COMPARED TO INVESTIGATOR’S CHOICE OF THERAPY IN PARTICIPANTS OVER 18 YEARS OF AGE WITH More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Razvan Popescu | Pfizer Inc. |
Tumor Zentrum Aarau - Hirslanden Medical Center, Aarau Solothurner Spitäler AG - Kantonsspital Olten, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.07.2024 | |||
| 2024-01118 |
Estimates of the short-term Efficacy of Talineuren and Placebo in patients with Parkinson disease: A randomized, placebo-controlled, double-blinded, parallel 2-arm, multi-centre pilot trial |
clinical trial | drugs | phase 1/2 | multicentric | C | Dr. med. Michael Schüpbach | InnoMedica Schweiz AG |
Neurologisches Institut Konolfingen, 3510 Konolfingen Kantonsspital St. Gallen, St. Gallen |
Kantonale Ethikkommission Bern | Ethikkommission Ostschweiz (EKOS) | 27.08.2024 | |||
| 2024-01108 |
PeRfusiOn Post tHrombEcTomy (PROPHET) A prospective, observational diagnostic accuracy study |
non clinical, involving persons | multicentric | A | Prof. Dr. med. Johannes Kaesmacher | Neuroradiologie |
Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie, Bern Diagnostische und interventionelle Neuroradiologie Klinik für Radiologie und Nuklearmedizin, Basel |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.08.2024 | |||||
| 2024-01097 |
M20-645: A Phase 3 Multicenter, Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Lutikizumab in Adult and Adolescent Subjects with Moderate to Severe Hidraden More ... |
clinical trial | drugs | phase 3 | multicentric | C | Dr. Ieva Saulite | AbbVie Inc. |
Klinik für Dermatologie, Venerologie und Allergologie, Kantonsspital St.Gallen, St. Gallen Department of Dermatology, Inselspital Bern, Bern Dermatology & Skin Care Clinic, Buochs Clinic for Dermatolo More ... |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 21.08.2024 | yes | ||
| 2024-01084 | International retrospective multicenter study of non-traumatic emergency pancreatoduodenectomy | personal data/biological material | multicentric | PD Dre Emilie Uldry | Division of Hepatobiliary and Pancreatic Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research |
CHUV, Lausanne Regional Hospital Lugano (EOC), Lugano |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Comitato etico cantonale Ticino | 30.05.2024 | ||||||
| 2024-01072 | Automated Scoring of Neuropsychological Tests | personal data/biological material | multicentric | Prof. Nicolas Langer | University of Zurich |
University of Zurich, Zürich Clinic Bellikon, Bellikon |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.08.2024 | ||||||
| 2024-01067 | Incidenza e fattori predittivi clinici ed anatomo-patologici nei tumori follicolari non invasivi della tiroide ad incerto potenziale di malignità (NIFTP)/ Incidence and clinicopathological factors for More ... | personal data/biological material | multicentric | Petra Makovac | ASUGI - Azienda Sanitaria Universitaria Giuliano Isontina – UCO Clinica Chirurgica |
EOC, Mendrisio HUG, Genève |
Comitato etico cantonale Ticino | Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.08.2024 | ||||||
| 2024-01051 | A Phase III, Multicentre, Randomised, Double-Blind Study to Assess the Safety and Efficacy of Emactuzumab vs. Placebo in Subjects with Tenosynovial Giant Cell Tumour (Short title: TANGENT) | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med. Attila Kollar | SynOx Therapeutics Ltd. |
Inselspital, Universitätsspital Bern, Bern Universitätsspital Basel, Basel |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.08.2024 | yes | ||