| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-D0043 |
Clinical Performance Study Protocol for PD-L1 IHC 22C3 pharmDx on Non-Squamous Non-Small Cell Lung Cancer Specimens. Supplement to Clinical Trial Protocol DS1062-A-U303. |
clinical trial | in vitro diagnostic medical devices | multicentric | C1 | Dr. med. / Pirmin / Haeuptle | Daiichi Sankyo Inc. |
KSBL Baselland, Liestal Spital STS AG, Thun KSSG, Rorschacher Strasse 95 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS) | 24.08.2023 | ||||
| 2023-D0029 | Robotic minimAlly invaSive inguinAl Hernia rEpAir with Dexter® | clinical trial | medical devices | multicentric | A1 | Prof. Dr. med. Stefan Breitenstein | Distalmotion SA |
Kantonsspital Winterthur, Winterthur Spital Tiefenau, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 02.05.2023 | ||||
| 2023-D0026 | Renal Denervation in Patients with Recurrent Atrial Fibrillation after Successful Pulmonary Vein Isolation (REDE-AF): a national, multi-centre, prospective, single-arm, pre-to-post treatment, medical- More ... | clinical trial | medical devices | multicentric | C1 | Prof. Dr. med. Laurent Roten | Insel Gruppe AG |
Insel Gruppe AG, Bern Universitätsspital Basel, Petergraben 4 |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.06.2023 | ||||
| 2023-D0024 |
Diagnostic Protocol for VENTANA FGFR2b (FPR2-D) RxDx Assay in Amgen Study 20210098 |
clinical trial | in vitro diagnostic medical devices | multicentric | C2 | Dr. Martin Dave Berger | Ventana Medical Systems, Inc. |
Inselspital, University Hospital Bern, Bern Universitätsspital Basel, Medical Oncology Petersgraben 4 Hôpitaux universitaires de Genève, Service d'oncologie Rue Gabrielle-Perret-Gentil University More ... |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER) | 10.05.2023 | ||||
| 2023-D0023 | Feasibility and efficacy of a transdiagnostic app-based psychological aftercare intervention | clinical trial | medical devices | multicentric | A1 | Dr. Andreea Visla | Universitäre Psychiatrische Kliniken Basel |
Universitäre Psychiatrische Kliniken, Basel Psychiatrische Dienste Aargau, Klinik für Psychiatrie und Psychotherapie Königs |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.05.2023 | ||||
| 2023-D0016 |
A Combination of Low-Energy Ultrasound, Electrical and Magnetic Field Stimulation in Patients with Therapy-Resistant Myofascial Pain Syndrome: A Randomized, Controlled, Double-Blind Multi-Center Stu More ... |
clinical trial | medical devices | multicentric | C2 | PD Dr. med. Christophe Perruchoud | SOBET AG |
Hôpital de La Tour, 1217 Meyrin Salem-Spital Bern, Bern Schmerzklinik Zürich, Wallisellenstr. 301a |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 17.04.2023 | ||||
| 2023-D0011 | Multicentric prospective clinical study to evaluate the Aktiia Optical Blood Pressure Monitoring (OBPM) device compared to standard Home Blood Pressure Monitoring (HBPM) in hypertensive patients when More ... | clinical trial | medical devices | multicentric | A1 | Dr Grégoire WUERZNER | AKTIIA SA |
CHUV, Lausanne HUG, Rue Gabrielle-Perret-Gentil 4, |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.05.2023 | ||||
| 2023-D0006 | MO42720 - INTERVENTIONAL PLATFORM STUDY INVESTIGATING THE IMPACT OF DIGITAL HEALTH SOLUTIONS ON HEALTH OUTCOMES AND HEALTH-CARE RESOURCE UTILIZATION IN PARTICIPANTS RECEIVING SYSTEMIC TREATMENT IN CLI More ... | clinical trial | medical devices | multicentric | A1 | Dr. med. Hasna Bouchaab | Roche Pharma (Schweiz) AG |
Centre hospitalier universitaire vaudois (CHUV), Lausanne Tumor Zentrum Aarau, Rain 34 Hôpitaux universitaires de Genève, Rue Gabrielle-Perret-Gentil 4 Stadtspital Zürich Triemli, Med. Onkologie und H More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Zürich, Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.05.2023 | ||||
| 2023-01564 | Outcome of dual kidney transplantation in Switzerland – a national cohort study | personal data/biological material | multicentric | Dr. med. Christian Kuhn |
Kantonsspital St. Gallen, St. Gallen University Hospital of Bern, Department of Nephrology and Hypertension, Bern University Hospital of Bern, Department of Nephrology and Hypertension, Basel Universi More ... |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Com More ... | 07.09.2023 | |||||||
| 2023-01405 | Assessing allergenicity of novel allergens using blood cultures from individuals with food allergies | non clinical, involving persons | multicentric | A | Professor Pål Johansen, PhD |
Department of Dermatology, University of Zurich, Zurich Department of Paediatrics, Hospital Baden, Baden Dermatologische Klinik, Universitätsspital Zürich, Zurich Department of Allergology, Children’s More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 26.09.2023 | yes | |||||
| 2023-01346 | Observational study over the last 20 years of congenital pulmonary airways malformations in children: Epidemiological evolution or technological advances ? | personal data/biological material | multicentric | Dre. Vidal Isabelle | Hôpitaux universitaires de Genève |
Hôpitaux universitaires de Genève, Genève CHUV, Lausanne |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.11.2012 | ||||||
| 2023-01328 |
An open-label, multicenter, single-arm, post-marketing trial to evaluate efficacy and safety and the impact of immunogenicity on efficacy, safety, and pharmacokinetics of spesolimab i.v. in treatme More ... |
clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Julia-Tatjana Maul | Boehringer Ingelheim International GmbH |
Universitätsspital Zürich, Zürich CHUV Dermatologie, Lausanne |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 22.09.2023 | |||
| 2023-01265 | BO44426 - A PHASE Ib/II, OPEN-LABEL, MULTICENTER STUDY EVALUATING THE SAFETY, ACTIVITY, AND PHARMACOKINETICS OF GDC-6036 IN COMBINATION WITH OTHER ANTI-CANCER THERAPIES IN PATIENTS WITH PREVIOUSLY UNT More ... | clinical trial | drugs | phase 1/2 | multicentric | C | Dr. med. David König | Roche Pharma (Schweiz) AG |
Universitätsspital Basel, Basel Insel Gruppe AG, Inselspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 21.09.2023 | |||
| 2023-01248 | Leptomeningeal Collaterals in INtracErebral Hemorrhage: Association with Hematoma Size and Expansion | personal data/biological material | multicentric | Prof. Dr. Gian Marco De Marchis | Cantonal Hospital St.Gallen |
Cantonal Hospital Basel, St.Gallen University Hospital Basel, Basel EOC Neurocenter of Southern Switzerland, Lugano |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Comitato etico cantonale Ticino | 14.07.2023 | ||||||
| 2023-01217 | Fully digital occlusion planning in orthognathic surgery | personal data/biological material | multicentric | Prof. Dr. med. Dr. med. dent. Philipp Metzler | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.07.2023 | ||||||
| 2023-01213 | Semaglutide-to-Tirzepatid-Switch (STS-3)-Studie: Prospektive Beobachtungsstudie eines zusätzlichen Effekts auf die glykämische Kontrolle und das Körpergewicht bei Patienten mit Diabetes, die von einer More ... | personal data/biological material | multicentric | Prof. Dr. Gottfried Rudofsky | Praxis Prof. Rudofsky |
Praxis Prof. Rudofsky, Olten Stoffwechselzentrum St. Gallen, St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS) | 23.08.2023 | ||||||
| 2023-01212 | The causal effect of surgical and orthotics treatments to improve walking in persons with a neurological disorder, including cerebral palsy and those toe walking. | personal data/biological material | multicentric | Dr. Morgan Sangeux | UKBB |
UKBB, Basel HUG, Genève |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.08.2023 | ||||||
| 2023-01188 | Asthma Control in Severe Asthma Patients Treated with Tezepelumab: a Prospective, Observational, Real-World Evidence Study (ASCENT) | non clinical, involving persons | multicentric | A | Prof Dr Daiana Stolz | AstraZeneca |
Universitätsspital Basel, Basel medicispecialisti.ch, Lugano Centre Hospitalier du Valais Romand, Sion |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 21.09.2023 | |||||
| 2023-01179 | Real-world analysis of Oncotype DX Test in patients with early breast cancer. An analysis of clinical management and management of systemic therapy in patients with early breast cancer - A retrospecti More ... | personal data/biological material | multicentric | PD Dr Marcus Vetter | Kantonsspital Baselland, Liestal |
Kantonsspital Baselland, Liestal, Liestal Breast Cancer Center, University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.08.2023 | ||||||
| 2023-01169 | MK-6024-013: A Phase 2b Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Efinopegdutide (MK-6024) in Adults With Precirrhotic Nonalcoholic Steatoh More ... | clinical trial | combination drugs/devices | phase 2 | multicentric | C | Prof. Dr. med. Andreas Kremer | Merck Sharp & Dohme LLC |
UniversitätsSpital Zürich, Zürich Kantonsspital St. Gallen, St. Gallen Fondazione Epatocentro Ticino, Lugano Centre des maladies digestives Lausanne, Lausanne |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 19.09.2023 | |||