| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-02179 | Bilateral External Torque CT compared to Arthroscopic Hook Test for Detection of Syndesmotic Insufficiency | deceased persons | monocentric | Dr. med. Silvan Beeler | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 26.11.2021 | |||||||
| 2021-02178 | Phase 3 Follow-up Study of AAV5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated with Variants in the RPGR gene | clinical trial | gene therapy | multicentric | C | Prof.Hendrik Scholl | Janssen-Cilag International NV |
Universitätsspital Basel, Augenklinik, Basel Hôpital ophtalmique Jules-Gonin, Lausanne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.02.2022 | yes | |||
| 2021-02177 | Phase 3 Randomized, Controlled Study of AAV5-hRKp.RPGR for the Treatment of X-linked Retinitis Pigmentosa Associated with Variants in the RPGR gene | clinical trial | gene therapy | multicentric | C | Prof.Hendrik Scholl | Janssen-Cilag International NV |
Universitätsspital Basel, Augenklinik, Basel Service d’ophtalmologie de l’Université de Lausanne, Hôpital ophtalmique Jules-Gonin, Unité d’oculogénétique, Lausanne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.03.2022 | yes | |||
| 2021-02176 | Efficacy and safety of bariatric surgery | personal data/biological material | monocentric | PD Dr. med. Emanuel Burri | Kantonsspital Baselland |
Kantonsspital Baselland, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.11.2021 | |||||||
| 2021-02175 | COMAP-CHBP : cohorte prospective de patients souffrant de pathologie pancréatique en cours d’investigations, destinée à étudier les informations apportées par les analyses d’échantillons biologiques e More ... | personal data/biological material | monocentric | Dr Jean-Louis Frossard | Rue Gabrielle-Perret-Gentil 4 |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 25.01.2022 | |||||||
| 2021-02174 | Biomarqueurs d'homéostasie dans la peau de patients atteints de dermatoses faciales chroniques | personal data/biological material | monocentric | Pr. Jean Hilaire SAURAT | Dermatology Office |
PO 22 rue de l'Athénée, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.03.2023 | |||||||
| 2021-02173 | Les co-occupations des adultes vivant une relation intime comprenant un adulte ayant un TSA. | non clinical, involving persons | monocentric | A | Ass. Prof. Isabel Margot-Cattin | Haute Ecole de Travail Social et de la Santé - Lausanne (HETSL) |
Haute école de Travail Social et de la Santé - Lausanne, (HES-SO), Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 03.02.2022 | Study has ended | |||||
| 2021-02172 | TRI0344 -Establishment of novel mouse xenografts derived from human uveal- and cutaneous melanoma tumor biopsies and evaluation targeting antibody drug conjugates | personal data/biological material | monocentric | PhD Michael Rugaard Jensen | Novartis Pharma AG - NIBR |
Novartis Pharma AG, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.03.2022 | |||||||
| 2021-02169 | Bildgebung in der Diagnostik der Riesenzellvaskulitis bzw. Grossgefässvaskulitis | personal data/biological material | monocentric | Dr. med. Luca Seitz | Inselspital - Klinik für Rheumatologie und Immunologie |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 30.11.2022 | |||||||
| 2021-02168 | Investigation of assistive control strategies for the hip joint targeting healthy people | non clinical, involving persons | monocentric | A | Mohamed Bouri | EPFL STI IBI-STI BIOROB/REHAssist |
EPFL STI IBI-STI BIOROB/REHAssist, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.01.2022 | Study has ended | |||||
| 2021-02166 | Effect of Physiotherapy in Patients Presenting to the Emergency Department with Nonspecific Lower Back Pain. A Brief Intervention Focusing on Patient Reported Outcomes | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Roland Bingisser | Notfallzentrum |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.12.2021 | |||||
| 2021-02165 | Effect of Physiotherapy in Patients Presenting to the Emergency Department after a Fall. A Brief Intervention Focusing on Patient Reported Outcomes | clinical trial | other clinical trials | monocentric | A | Prof. Roland Bingisser |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.12.2021 | ||||||
| 2021-02164 | FLowTriever All-Comer Registry for Patient Safety and Hemodynamics (FLASH) | non clinical, involving persons | multicentric | A | Dr. Stefano Barco | Inari Medical Europe GmbH |
Universitätsspital Zürich, Zürich Inselspital, bern Kantonsspital Sankt Gallen, Sankt Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 25.01.2022 | |||||
| 2021-02163 | The Management of Chiari I Malformation-Syrinx Complex Accompanied by Hydrocephalus | personal data/biological material | monocentric | PD Dr Jehuda Soleman | Unispital Basel und UKBB |
USB, Dept Neurochirurgie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.12.2021 | |||||||
| 2021-02162 | Investigating the molecular mechanisms of the ADP-ribosyltransferase PARP6 in manifestation and progression of heart failure | personal data/biological material | monocentric | Prof/Michael/Hottiger | University of Zurich |
University of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 01.03.2022 | |||||||
| 2021-02161 |
20170104_A Phase 2, Dose-finding, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Safety and Efficacy of Efavaleukin Alfa Induction Therapy in Subjects with Mod More ... |
clinical trial | drugs | phase 2 | multicentric | C | Dr. Biedermann Luc | One Amgen Center Drive Thousand Oaks, CA 91320 |
Universitätsspital Zürich, Zürich Intesto BE, Bern Inselspital Bern, Bern Kantonsspital St. Gallen, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern | 07.01.2022 | |||
| 2021-02160 | Understanding the pathomechanisms leading to Autophagic Vacuolar Myopathies | personal data/biological material | monocentric | Prof. Perrine CASTETS | Centre Médical Universitaire |
CMU, Faculté de Médecine, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 02.11.2021 | |||||||
| 2021-02159 | Untersuchung von Stromazellen und Immunzellen im Knochenmark von Patienten mit akuter myeloischer Leukämie zur Charakterisierung der Mikroumgebung und Identifikation neuer Therapiestrategien | non clinical, involving persons | monocentric | A | Prof. Dr. med. Markus Manz |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 23.11.2021 | |||||||
| 2021-02158 |
ENTYVIO® Real-World Outcomes in Bio-naïve Crohn’s Disease Patients in Belgium, Australia, and Switzerland: An EVOLVE Observational Expansion Study |
personal data/biological material | multicentric | Michael Scharl | Takeda Development Center Americas, Inc. (TDC Americas) |
Universitätsspital Zürich, Zürich Inselspital Bern, Bern Berner IBD Study Group c/o Intesto KLG, Gastroenterologische Praxis, Crohn-Colitis-Zentrum, Bern Clarunis Universitäres Bauchzenturm Basel, Bas More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 14.01.2022 | Study has ended | |||||
| 2021-02157 | Randomised, double-blind, placebo-controlled and parallel group trial to investigate the effects of two doses (up-titration to a fixed dose regimen) of oral BI 685509 on portal hypertension after 24 w More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. Markus Heim | Boehringer Ingelheim RCV GmbH & Co KG |
Universitätsspital Basel, Clarunis Universitäres Bauchzentrum, Basel Ente Ospedaliero Cantonale, Servicio di Gastroenterologia e Epatologia, Ospedale Italiano di Lugano, 6962 Lugano-Viganello |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Comitato etico cantonale Ticino | 08.02.2022 | Study has ended | ||