| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-00430 | Immunogenicity of RNA-based COVID-19 vaccines in patients treated with immunosuppressive drugs – a prospective observational cohort study | non clinical, involving persons | multicentric | A | Dre Christiane Eberhardt | Hôpitaux Universitaires de Genève |
University Hospitals Geneva, Geneva University Hospital Basel, Basel |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.03.2021 | Study has ended | ||||
| 2021-00429 |
A Randomized, Double Blind, Placebo-Controlled Phase 3 Study of Abemaciclib plus Standard Adjuvant Endocrine Therapy in Participants with High-Risk, Node-Positive, HR+, HER2+ Early Breast Cancer Who More ... |
clinical trial | drugs | phase 3 | multicentric | B | PD Dr. Marcus Vetter | Eli Lilly Cork Ltd. |
Universitätsspital Basel, Basel Inselspital Bern, Bern Hirslanden Clinique des Grangettes, Chêne-Bougeries, Brustzentrum Ostschweiz, St. Gallen Istituto Oncologico della Svizzera Italiana, Ospedale Sa More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 26.05.2021 | Study has ended | ||
| 2021-00428 | Phase 3 Randomized Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non- Small Cell Lung Cancer with or without Actionable Genomic Alterations (TROPION-Lung01) | clinical trial | drugs | phase 3 | multicentric | C | Dr. Ferdinando Cerciello | Daiichi Sankyo, Inc. |
Universitätsklinik für Medizinische Onkologie, Inselspital, Bern Kantonsspital St. Gallen, Klinik für Onkologie und Haematologie, 9007 St. Gallen Stadtspital Zürich Triemli, Klinik für Medizinische O More ... |
Kantonale Ethikkommission Bern | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 16.08.2021 | |||
| 2021-00427 | Prevalence of SARS-CoV-2 positivity in infants with bronchiolitis | non clinical, involving persons | monocentric | A | Dr.ssa med. Vanoni Federica | IRCCS Burlo Trieste |
IPSI (Istituto Pediatrico della Svizzera Italiana), Bellinzona |
Comitato etico cantonale Ticino | 07.04.2021 | yes | |||||
| 2021-00426 | Dysphagia incidence in COVID-19 ICU patients | personal data/biological material | monocentric | Dr. med. Patrick Zuercher | Department of Intensive Care Medicine |
Inselspital, Bern University Hospital Freiburgstrasse 18, Bern |
Kantonale Ethikkommission Bern | 01.03.2021 | |||||||
| 2021-00425 | BO41932 TAPISTRY - TUMOR-AGNOSTIC PRECISION IMMUNO-ONCOLOGY AND SOMATIC TARGETING RATIONAL FOR YOU (TAPISTRY) PHASE II PLATFORM TRIAL | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. Anastasios Stathis | Roche Pharma (Schweiz) AG |
Istituto Oncologico della Svizzera Italiana – IOSI, CH-6500 Bellinzona INSELSPITAL, Universitätsspital Bern, Klinik und Poliklinik für Medizinische Onkologie, Lory Haus, Stock 1, 129, CH-3010 Bern Uni More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 23.09.2021 | yes | ||
| 2021-00424 | Database Development for the Study of Cardiovascular Sequelae of Severe COVID Infection | personal data/biological material | monocentric | Prof. Dr. med. Donat R. Spahn | Institut für Anästhesiologie |
Institut für Anästhesiologie - USZ, Zürich |
Kantonale Ethikkommission Zürich | 09.03.2021 | |||||||
| 2021-00423 | Zahnärztliche Eingriffe in Allgemeinanästhesie - eine retrospektive Studie | personal data/biological material | monocentric | Prof. Dr. Andreas Filippi | Klinik für Oralchirurgie UZB |
Klinik für Oralchirurgie UZB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.04.2021 | |||||||
| 2021-00422 | Resting Heart Rate Monitoring for Optimized Treatment and Surveillance of Hyperthyroidism – the PULSAR-Study | non clinical, involving persons | monocentric | A | MD Claudia Irene Maushart | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.04.2021 | Study has ended | |||||
| 2021-00421 | A Phase 2 Randomized Study of Relatlimab plus Nivolumab in Combination with Chemotherapy vs. Nivolumab in Combination with Chemotherapy as First Line Treatment for Participants with Stage IV or Recurr More ... | clinical trial | drugs | phase 2 | multicentric | C | Dr. med. David König | Bristol-Myers Squibb Switzerland |
Universitätsspital Basel, Basel Kantonspital St. Gallen, St. Gallen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Ostschweiz (EKOS) | 13.08.2021 | |||
| 2021-00420 | Study of human photoreceptors using cutting edge microscopy techniques | deceased persons | monocentric | Dr Virginie Hamel | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 25.03.2021 | |||||||
| 2021-00419 | CAAA617B12302 - PSMAfore: Phase III, Open-label, Multi-Center, Randomized Study Comparing 177Lu-PSMA-617 vs. a Change of Novel Androgen Axis Drugs in the Treatment of Taxane Naïve Men with Progressive More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Dominik Berthold | Novartis Pharma Schweiz AG |
CHUV, Lausanne Kantonsspital Baden, Baden Universitätsspital Zürich, Zürich |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 24.06.2021 | |||
| 2021-00418 | Identification of patients with clinically relevant sleep apnea with a contactless device in rehabilitation clinic | clinical trial | medical devices | monocentric | A1 | Dr. Jens Acker | Sleepiz AG |
KSM Klinik für Schlafmedizin, Bad Zurzach |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.03.2021 | |||||
| 2021-00417 | Identifizierung von Biomarkern und Individuellen Medikamenten Sensitivitäten mittels Multi-Omics und funktionalen Screens in Soliden Tumoren epithelialen und mesenchymalen Ursprungs | personal data/biological material | monocentric | Prof. Dr. med. Chantal Pauli | Pathologie und Molekularpathologie |
Pathologie und Molekularpathologie, Zurich |
Kantonale Ethikkommission Zürich | 24.08.2021 | |||||||
| 2021-00416 | DiamondTemp™ Global Registry | personal data/biological material | monocentric | Prof. Dr. med. Tobias Reichlin | Medtronic Bakken Research Center |
Inselspital-Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 08.07.2021 | |||||||
| 2021-00415 | Le vécu des parents de la naissance chirurgicale: une recherche socio-anthropologique sur la culture de la césarienne en Suisse | non clinical, involving persons | monocentric | A | Prof Irene Maffi | UNIL - SSP |
UNIL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.05.2021 | Study has ended | |||||
| 2021-00414 | Capacity of human image recognition | non clinical, involving persons | monocentric | A | Prof. Radek Ptak |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 20.04.2021 | |||||||
| 2021-00413 | Probing immune response to controlled bacteria for cancer therapy | non clinical, involving persons | monocentric | A | Prof. Simone Schürle | ETH Zurich |
ETH Zürich, Zürich |
Kantonale Ethikkommission Zürich | 27.04.2021 | ||||||
| 2021-00412 | Retrospektive Datenanalyse zur Bestimmung der klinischen Relevanz der Laborparameter (S100B, LDH, CRP) bei Melanompatienten mit und ohne Hirnmetastasen | personal data/biological material | monocentric | Prof. Dr. med. Reinhard Dummer | Dermatologische Klinik des Universitätsspitals Zürich |
dermatologische Klinik des Universitätsspitals Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.04.2021 | |||||||
| 2021-00411 | Pilotstudie Verschreibung im Hospiz-Setting - ein retrospektive Datenanalyse | personal data/biological material | monocentric | Dr. phil. II Carla Meyer-Massetti | Universität Basel |
Universität Basel, Klinische Pharmazie & Epidemiologie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.03.2021 | Study has ended | ||||||