| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-00410 | A retrospective study of the evolution of chronic healthcare conditions in a Swiss PICU over the last decade | personal data/biological material | monocentric | Prof. Dr. med. Luregn Schlapbach Tribolet | Intensivmedizin und Neonatologie |
Universtitäts-Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 24.08.2021 | |||||||
| 2021-00409 | Risiko für eine intrazerebrale oder gastrointestinale Blutung bei off-label Dosierung von direkten oralen Antikoagulantien (DOAK) bei Patienten mit nicht-valvulärem Vorhofflimmern (nvVHF) | personal data/biological material | monocentric | Dr Patrick Imfeld | University Hospital Basel, Hospital Pharmacy |
University Hospital Basel, Hospital Pharmacy, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.04.2021 | |||||||
| 2021-00408 | Are changes in pain perception associated with changes in brain activity patterns in persons with spinal cord injury and neuropathic pain after a virtual walking training program? - A pilot study | non clinical, involving persons | monocentric | A | Gunther Landmann | HESAV |
Schweizer Paraplegiker-Zentrum, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.05.2021 | ||||||
| 2021-00407 | ENCASE II - Randomized, two-arm, multicenter study to evaluate the safety and efficacy of Dura Sealant Patch in reducing CSF leakage following elective cranial surgery | clinical trial | medical devices | monocentric | A1 | MD, PhD Menno Robbert Germans | Polyganics BV |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 04.05.2021 | Study has ended | ||||
| 2021-00406 | Validation of a visually supported Food Frequency Questionnaire (bachelor’s thesis) | non clinical, involving persons | monocentric | A | Prof Dr. Arno Schmidt-Trucksäss |
Universität Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 31.03.2021 | |||||||
| 2021-00405 | Effects of MDMA-like substances in healthy subjects | clinical trial | other clinical trials | monocentric | B | Prof. Dr. med Matthias Liechti | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.04.2021 | |||||
| 2021-00404 | Head Form of the Newborns and Position of Fontanelles Depending on the Head Form within Twenty-four Hours after Delivery. | non clinical, involving persons | monocentric | A | Dr. Dalia Balsyte | Klinik für Geburtshilfe, Universitätsspital Zürich |
Klinik für Geburtshilfe, Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 20.04.2021 | yes | |||||
| 2021-00403 | Validation of a digital twin to predict the adaptation of muscle strength and muscle size due to strength training. | clinical trial | other clinical trials | monocentric | A | PD Dr. Dr. Silvio Lorenzetti | Swiss Federal Institute of Sport Magglingen |
Swiss Federal Institute of Sport, Magglingen |
Kantonale Ethikkommission Bern | 07.02.2022 | |||||
| 2021-00402 | Firm Observational Clinical Unicenter Study on Guillain Barré Syndrome (FOCUS on GBS) | personal data/biological material | monocentric | Prof. Raoul Sutter | University Hospital Basel |
University Hospital of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.03.2021 | |||||||
| 2021-00401 | Identifying relevant cellular and molecular features in patients with neurodevelopmental disorders using organoids | non clinical, involving persons | monocentric | A | Prof. Denis Jabaudon | Université de Genève |
Université de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 22.04.2021 | yes | |||||
| 2021-00400 | A retrospective comparison between one-stage and two-stage orbital reconstruction in patients suffering from combined injuries of the midface | personal data/biological material | monocentric | PD Dr. Dr. Thomas Gander | Klinik für Mund-, Kiefer- und Gesichtschirurgie UniversitätsSpital Zürich |
Klinik für Mund-, Kiefer- und Gesichtschirurgie USZ, Zürich |
Kantonale Ethikkommission Zürich | 27.04.2021 | |||||||
| 2021-00399 | Colchicine for patients with aortic stenosis undergoing transcatheter aortic valve replacement (Co-STAR): a randomized-controlled trial | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Thomas Pilgrim | Insel Gruppe AG |
Universitätsklinik für Kardiologie, Inselspital, Bern |
Kantonale Ethikkommission Bern | 17.09.2021 | ||||
| 2021-00398 |
HOVON 155 AML / SAKK 30/18 A randomized phase II multicenter study to assess the tolerability and efficacy of the addition of midostaurin to 10-day decitabine in UNFIT (i.e. HCT-CI ≥ 3) adult AML a More ... |
clinical trial | drugs | phase 2 | multicentric | B | Dr. med. Sabine Blum | HOVON |
CHUV, Lausanne Inselspital, Bern Universitätsspital Basel, Basel |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 27.05.2021 | |||
| 2021-00397 | Registry for pregnant women using the PREGrec mobile application enabling a participative science approach | non clinical, involving persons | monocentric | A | Dre Alice Panchaud | CHUV |
CHUV, lAUSANNE |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 12.05.2021 | ||||||
| 2021-00395 | Analysis of aldosterone synthase expression and aldosterone production in human, primary and immortalized cell lines including PBMCs of hyperaldosteronism patients | personal data/biological material | monocentric | Prof Dr Bruno Vogt |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 31.10.2022 | ||||||||
| 2021-00394 | Registry of Long term outcomes of aortic aneurysm treatment | non clinical, involving persons | monocentric | A | Dr Sébastien Deglise | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 25.03.2021 | ||||||
| 2021-00393 | SYSTEMIC PHYSIOLOGY AUGMENTED FUNCTIONAL NEAR-INFRARED SPECTROSCOPY | non clinical, involving persons | multicentric | A | Prof. Dr. Martin Wolf | University of Zurich/University Hospital Zurich |
University of Zurich/University Hospital Zurich, Zurich University of Bern, Bern University of Zurich/University Hospital Zurich, Schlieren |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 27.04.2021 | |||||
| 2021-00392 | The Neural Interplay of Episodic Simulation and Affective Empathy | non clinical, involving persons | monocentric | A | Prof. David Sander | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 31.05.2021 | ||||||
| 2021-00391 | Design and development of an artificial intelligence in the treatment of multiple injured patients based on the IBM Watson technology | personal data/biological material | monocentric | PD Dr.med. Ladislav Mica | University Hospital of Zurich |
University Hospital of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 09.03.2021 | |||||||
| 2021-00390 | Le suivi de patients ayant présenté une maladie d’altitude aigue sévère durant les 15 dernières années en Valais. | non clinical, involving persons | monocentric | A | Dr Pierre Métrailler | Hôpital du Valais, Centre Hospitalier du Valais Romand - Service des urgences |
HVS, Sion |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 23.06.2021 | ||||||