| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2019-01180 | Deutsche prospektive Registerstudie zur Erfassung der Behandlungspraxis von gynäkologischen Sarkomen in der klinischen Routine (REGSA) | personal data/biological material | multicentric | Prof. Dr. Heubner | NOGGO e.V. |
Kantonsspital Baden, Baden Luzerner Kantonsspital, Frauenklinik, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.07.2019 | ||||||
| 2019-01178 | A Target Validation Study of Fimepinostat in Children and Young Adults with Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG), Recurrent Medulloblastoma, or Recurrent High-Grade Glioma (HGG) | clinical trial | drugs | n/a | monocentric | C | Dr. Nicolas Gerber | University of California San Francisco |
Universitäts Kinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 28.10.2019 | yes | |||
| 2019-01176 | ECG Belt for CRT Response (ECG Belt) | clinical trial | medical devices | monocentric | C2 | Prof. Dr. med. Etienne Pruvot | Medtronic Bakken Research Center B.V. |
CHUV - Service de cardiologie, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.11.2019 | Study has ended | ||||
| 2019-01175 | Efficacy of using a toilet footstool during defecation in chronic idiopathic constipation: The Thinker trial. Pilot study for a randomized trial | non clinical, involving persons | monocentric | A | Dr Hubert Maisonneuve | Unige faculty of medicine primary care unit |
Primary Care Unit, Faculty of medicine, University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 01.10.2019 | yes | Study has ended | ||||
| 2019-01174 | DP13C201 – A Phase II Study in Patients with Primary Aldosteronism to Evaluate the Efficacy, Safety and Tolerability of the Aldosterone Synthase Inhibitor, DP13, over an 8-week Treatment Period | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Bruno Vogt | DAMIAN Pharma AG |
Inselspital, Bern CHUV, Lausanne |
Kantonale Ethikkommission Bern | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.12.2019 | Study has ended | ||
| 2019-01173 | REACH - A Phase III randomized trial of avelumab-cetuximab-Radiotherapy versus standards of care in locally advanced squamous cell carcinoma of the head and neck | clinical trial | drugs | phase 3 | monocentric | C | Dr Petr Szturz | GORTEC |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.12.2019 | ||||
| 2019-01172 | EsPhALL2017/COGAALL1631: International phase 3 trial in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) testing imatinib in combination with two different cytotoxic chemotherap More ... | clinical trial | drugs | phase 3 | multicentric | B | Dr. med. Nicole Bodmer | Pediatric Clinic - University of Milano-Bicocca |
Universitäts-Kinderspital Zürich, Zürich Inselspital, Bern Kantonsspital Aarau, Aarau Universitätsspital beider Basel, Basel Luzerner Kantonsspital, Luzern HUG, Genève Ostschweizer Kinderspital, St. G More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... | 20.08.2019 | yes | ||
| 2019-01171 | The impact of patient age on postoperative outcomes, treatment costs, and long-term outcomes following pancreatic surgery | personal data/biological material | monocentric | Prof. Dr. Beat Gloor | Inselspital Bern University Clinic for Visceral Surgery und Medicin |
Inselspital Bern, University Clinic for Visceral Surgery und Medicin Bern, Bern |
Kantonale Ethikkommission Bern | 07.08.2019 | |||||||
| 2019-01170 | Specialised Paediatric PAlliativE CaRe: Assessing family, healthcare professionals and health system outcomes in a multi-site context of various care settings (SPhAERA) | non clinical, involving persons | multicentric | A | Dr. sc. med. Karin Zimmermann | University-Children's Hospital Zurich |
University-Children's Hospital Zurich, Zurich Inselspital Bern University Hospital, Department of Pediatrics, Bern Children's Hospital Aarau, Aarau University Children's Hospital Basel, Basel |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern | 10.10.2019 | yes | ||||
| 2019-01169 | Clinical and immunological patterns of non-infectious aortic graft inflammation in bovine vs non-biological grafts | non clinical, involving persons | monocentric | A | Prof. Dr. med. Dr. h.c. Thierry Carrel | Insel Group AG, Dept. of Cardiovascular Surgery, University Hospital Bern |
Dept. of Cardiovascular Surgery, Bern |
Kantonale Ethikkommission Bern | 30.07.2019 | Study has ended | |||||
| 2019-01167 | Prevalence of hyperkalemia and other electrolyte disorders in patients with acute kidney injury in the emergency department – a retrospective study | personal data/biological material | monocentric | PD Dr. med. univ. Gregor Lindner | Bürgerspital Solothurn |
Bürgerspital Solothurn, Solothurn |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.07.2019 | Study has ended | ||||||
| 2019-01166 | A single center, randomized control study to compare efficacy and safety of femto-laser created clear corneal incisions with manually created clear corneal incisions during cataract surgery | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Bojan Pajic | Ziemer Ophthalmic Systems AG |
Augenzentrum ORASIS AG, Reinach |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.08.2019 | |||||
| 2019-01165 | Studying human immune cell phenotypes and trafficking from periphery across the human brain barriers into CNS tissue in CNS autoimmunity - A monocentric longitudinal observational study | non clinical, involving persons | monocentric | A | Dr.med. Anke Salmen | Universitätsklinik für Neurologie, Inselspital Bern |
Universitätsklinik für Neurologie, Bern |
Kantonale Ethikkommission Bern | 01.10.2019 | ||||||
| 2019-01164 | Analysis of the tumor microenvironment in tumors located in the central nervous system. | personal data/biological material | monocentric | Dr Valérie Dutoit | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.08.2019 | Study has ended | ||||||
| 2019-01163 | Clinical and radiographic outcomes following non-surgical mechanical therapy of peri-implantitis with or without adjunctive diode laser application: A 12-month double-blinded randomized clinical trial | clinical trial | medical devices | monocentric | A1 | Prof. Giovanni Salvi | University of Bern |
Department of Periodontology, University of Bern, Bern |
Kantonale Ethikkommission Bern | 06.11.2019 | Study has ended | ||||
| 2019-01162 |
PROPHETIC Studie Prognostication of Outcome in Patients with Out-of Hospital Cardiac Arrest Hospitalized in Intensive Care |
non clinical, involving persons | multicentric | A | Prof. Sabina Hunziker | University Hospital Basel |
Universitätsspital Basel, Basel Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.10.2019 | |||||
| 2019-01161 | FEASIBILITY OF AN INTERACTIVE TABLET-BASED EXERCISE PROGRAM FOR PEOPLE WITH CHRONICAL DISEASES | clinical trial | other clinical trials | monocentric | A | Mr. Damiano Zemp | EOC |
EOC, Mendrisio |
Comitato etico cantonale Ticino | 16.08.2019 | Study has ended | ||||
| 2019-01160 |
Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging A phase II prospective randomized multicentre study |
clinical trial | other clinical trials | multicentric | B | Prof. Dr. med. Matthias Guckenberger | Klinik für Radio-Onkologie |
UniversitätsSpital Zürich, Zürich Klinik Hirslanden, 8032 Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 04.11.2019 | Study has ended | |||
| 2019-01158 | The effect of Comorbidity on Outcome in Patients Hospitalized For Acute Heart Failure in Lausanne (LAU-AHF) | personal data/biological material | monocentric | Professor Dr. Roger Hullin | CHUV - BU44-2208 |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.07.2019 | Study has ended | ||||||
| 2019-01157 |
CNIS793X2101 - A phase I/Ib, open-label, multi-center dose escalation study of NIS793 in combination with PDR001 in adult patients with advanced malignancies |
clinical trial | drugs | phase 1 | monocentric | C | Prof. Dr. med. Markus Jörger | Novartis Pharma Schweiz AG |
Kantonsspital, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 09.08.2019 | Study has ended | |||