| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2020-01430 | Atezolizumab plus 8 Gy single-fraction radiotherapy for advanced, oligoprogressive NSCLC after upfront chemotherapy and anti-PD1 immunotherapy | clinical trial | drugs | phase 2 | multicentric | A | Dr med. Francesco Martucci | Istituto Oncologico della Svizzera Italiana |
Oncology Institute of Southern Switzerland, Bellinzona Geneva University Hospitals (HUG), Genève Cantonal Hospital of Graubünden (KSGR), Chur |
Comitato etico cantonale Ticino | Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.09.2020 | Study has ended | ||
| 2020-01429 | Herpes Simplex Virus Reactivation in Patients with Covid-19 and Acute Respiratory Distress Syndrome | personal data/biological material | monocentric | Alessandro F. Chiesa |
Ente Ospedaliero Cantonale, Bellinzona |
Comitato etico cantonale Ticino | 24.06.2020 | ||||||||
| 2020-01428 | The Swiss register RePreg networking with European Pregnancy registers in rheumatology: Joint data analysis | personal data/biological material | monocentric | Prof. Frauke Förger | Inselspital Bern |
Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 25.01.2023 | |||||||
| 2020-01427 | Conservative vs. surgical treatment of spinal burst fractures – a retrospective outcome analysis | personal data/biological material | monocentric | Prof. Dr. Christoph E. Albers | Inselspital - Orthopädie |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 07.12.2020 | |||||||
| 2020-01425 | Impact of the COVID-19 pandemic on the delay from symptom onset to first medical contact in patients with acute coronary syndromes undergoing percutaneous coronary intervention | non clinical, involving persons | monocentric | A | Dr Nils Perrin |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 17.06.2020 | |||||||
| 2020-01424 | Surgical site infections following spinal surgery with and without implants: Retrospective cohort study to compare management and outcome. | personal data/biological material | monocentric | PD Dr. med. Anna Conen, MSc | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.06.2020 | Study has ended | ||||||
| 2020-01422 | Amputationsfreies Überleben nach pedalen Bypässen (Limb salvage in pedal bypass) | personal data/biological material | monocentric | PD Dr.med.Vladimir Makaloski | Herz- und Gefässchirurgie |
Herz- und Gefässchirurgie Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 27.11.2020 | Study has ended | ||||||
| 2020-01421 | Evaluation of atelectasis formation with electrical impedance tomography during anesthesia for MRI in children | non clinical, involving persons | monocentric | A | Dr. med. Thomas Riva | Insel Spital, Bern |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 29.07.2021 | yes | Study has ended | ||||
| 2020-01420 | Preceding oral anticoagulation (direct oral anticoagulation (DOACS) or Vitamin K antagonists) and/or aniagreggation in ptients with SARS-CoV-2: impact on thromboembolic events and mortality | personal data/biological material | monocentric | Dr. med. Aleksandra Nobile-Skibinski | ORBV |
ORBV, Bellinzona |
Comitato etico cantonale Ticino | 24.06.2022 | |||||||
| 2020-01419 | Étude rétrospective sur le traitement de l’hallux rigidus sévère par arthroplastie d’interposition (CARTIVA SCI). | non clinical, involving persons | monocentric | A | Dr Victor Dubois-Ferrière | Service de chirurgie orthopedique et traumatologie de l'appareil moteur / HUG |
Service de Chirurgie Orthopédique et Traumatologie de l'Appareil Moteur, HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 14.09.2021 | ||||||
| 2020-01418 | Ultrasound-enhanced versus conventional catheter-directed thrombolysis for acute intermediate-high-risk pulmonary embolism. | clinical trial | medical devices | multicentric | A | Professor Salah Dine QANADLI | CHUV |
CHUV, Lausanne Hopital Riviera Chablais, Rennaz |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.05.2021 | ||||
| 2020-01415 | Double-blind, randomized, crossover drug-drug interaction study between pyrimethamine and metformin in healthy volunteers, aimed to identify potential endogenous biomarkers for the inhibition of renal More ... | clinical trial | drugs | n/a | monocentric | B | Dr Haithem Chtioui | Centre Hospitalier Universitaire Vaudois - CHUV |
Centre Hospitalier Universitaire Vaudois - CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.07.2020 | Study has ended | |||
| 2020-01414 | CCFZ533A2201 - A partially-blinded, active-controlled, multicenter, randomized study evaluating efficacy, safety, tolerability, pharmacokinetic (PK) and pharmacodynamic (PD) of an anti-CD40 monoclonal More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Rudolf Wüthrich | Novartis Pharma Schweiz AG |
Universitätsspital Zürich, Zürich Inselspital, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern | 08.09.2020 | Study has ended | ||
| 2020-01413 | Total-Body PET/CT – an intra-individual comparison with standard digital PET/CT | non clinical, involving persons | monocentric | A | Prof. Dr. med. A. Rominger | Inselspital Bern |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 29.10.2020 | Study has ended | |||||
| 2020-01412 | A randomized, double-blind placebo-controlled, Phase 3 study of Debio 1143 in combination with platinum-based chemotherapy and standard fractionation intensity-modulated radiotherapy in patients with More ... | clinical trial | drugs | phase 3 | multicentric | C | Petr Szturz | Merck Healthcare KGaA, an affiliate of Merck KGaA, Darmstadt, Germany |
Centre Hospitalier Universitaire Vaudois, Lausanne Inselspital, Bern University Hospital, Bern Hopitaux Universitaires de Geneve, Geneve |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) | 08.10.2020 | Study has ended | ||
| 2020-01411 | Reliability of prognostic scores for surgical decision-making in patients with operatively treated thoracolumbar spine metastases – experience of a single-center multidisciplinary treatment framework | personal data/biological material | monocentric | Dr Barges-Coll Juan |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 30.06.2022 | ||||||||
| 2020-01410 | Influence of Food on the Oral Bioavailability of Ladarixin 200 mg Capsule in Healthy Volunteers of Both Sexes. A Single dose (400 mg), Randomized, Open Label, Two-Way Crossover Study | clinical trial | drugs | phase 1 | monocentric | C | MD Milko Radicioni | Dompé farmaceutici S.p.A. |
CROSS Research S.A., Arzo |
Comitato etico cantonale Ticino | 17.06.2020 | Study has ended | |||
| 2020-01409 | Grandparents’ involvement and psychosocial outcomes when a grandchild is diagnosed with cancer: acute and long-term consequences | non clinical, involving persons | monocentric | A | Prof. Dr. Gisela Michel | University of Lucerne |
University of Lucerne, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.08.2020 | yes | Study has ended | ||||
| 2020-01408 |
A multi-centre, prospective, non-interventional single-arm study investigating clinical parameters associated with the use of once-daily oral semaglutide in a real-world adult population with type More ... |
non clinical, involving persons | multicentric | A | PD Dr. med. Thomas Züger | Novo Nordisk A/S |
Kantonsspital Olten, Olten Elfenaupraxis, Bern Gruppenpraxis Weststadt, 4500 Solothurn Praxis Dr. El-Haschimi, 5400 Baden Endocrinology, University Hospital Basel, 4031 Basel Praxis Schöngrund, Rotkre More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 19.08.2020 | Study has ended | ||||
| 2020-01407 |
Comparative bioavailability of sitagliptin after single dose of a new modified release formulation versus the marketed formulation Januvia® administered to healthy volunteers under fasting conditions More ... |
clinical trial | drugs | phase 1 | monocentric | C | Dr. Milko Radicioni | DPL Pharma S.p.A. |
CROSS Research S.A. Phase I Unit, CH-6864 Arzo, Switzerland |
Comitato etico cantonale Ticino | 17.06.2020 | Study has ended | |||