BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2022-D0101 Transcatheter Mitral Valve Replacement with the Medtronic Intrepid TMVR Transfemoral System in patients with severe symptomatic mitral regurgitation – APOLLO-EU Trial clinical trial medical devices monocentric C2 Prof. Dr. med. Stephan Windecker Medtronic Bakken Research Center B.V. Inselspital, Universitätsspital Bern, Bern
Kantonale Ethikkommission Bern 02.05.2023
2022-D0100 CARDIAC FLOW MEASUREMENTS IN PREGNANT WOMEN BY NON INVASIVE TECHNIQUES: COMPARISON BETWEEN USCOM, ICON and TRANS THORACIC ECHOGRAPHY. clinical trial medical devices monocentric A1 Dr Bénédicte LE TINIER Hôpitaux Universitaires de Genève Hopitaux universitaires de Genève, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 16.01.2023
2022-D0099 EndurAnt Stent Graft system vs ExcluDer endoprosthesis: a global, prospectiVe, rANdomized Clinical trial in sac rEgression clinical trial medical devices multicentric A1 Dr. Sébastien Déglise Medtronic Bakken Research Center Centre hospitalier universitaire vaudois, Lausanne
Luzerner Kantonsspital, Spitalstrasse
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Ethikkommission Nordwest- und Zentralschweiz EKNZ 17.01.2023
2022-D0098 Real-time deflectable guidewire in neuro-interventions study (SmartGUIDE) clinical trial medical devices multicentric C2 Prof. Dr. Paolo Machi Artiria Medical SA Geneva University Hospital - HUG, Geneva
Centre Hospitalier Universitaire Vaudois (CHUV), Service de radiodiagnostic et radiologie intervent
Commission Cantonale d'éthique de la recherche Genève (CCER) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 03.04.2023
2022-D0097 First clinical evaluation of a novel non-invasive glucose sensor technology in patients with type 1 diabetes: a single-arm pilot study clinical trial medical devices monocentric C2 Prof. Dr. med Markus Laimer DCB Research AG Universitätsklinik für Diabetologie, Endokrinologie, Ernährungsmedizin & Metabolismus (UDEM), Inselspital, Bern
Kantonale Ethikkommission Bern 03.02.2023 Study has ended
2022-D0096 An Open-label Randomized Phase 3 Study of Tucatinib in Combination with Trastuzumab and mFOLFOX6 versus mFOLFOX6 given with or without either Cetuximab or Bevacizumab as First-line Treatment for Subje More ... clinical trial in vitro diagnostic medical devices IVD-MD multicentric C1 Dr. Ralph Fritsch Seagen Inc., a wholly owned subsidiary of Pfizer Universitätsspital Zürich, Klinik für Medizinische Onkologie und Hämatologie, Zürich
Kantonsspital Winterthur, Brauerstr. 15
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 30.06.2023
2022-D0094 A Prospective, Randomized, Blinded Evaluator, Multicenter, Clinical Study to Evaluate Safety and Effectiveness of TEOSYAL® TPVM versus COMPARATOR for the remodeling of the lower face. clinical trial medical devices multicentric C2 Dr Navid Alizadeh TEOXANE SA Care Geneva Aesthetics, Geneva
Clinique Cleage, Place du Molard 5
Private clinic, Avenue de Champel 24
Clinique des Grangettes, Route de Chêne 110
Clinique de la Croix d’Or, Rue de la Croix-d’Or 7
CHU More ...
Commission Cantonale d'éthique de la recherche Genève (CCER) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) 04.01.2023
2022-D0093 Post-Market, Randomized, Controlled, Multicenter, Prospective Trial Investigating Efficacy and Safety of Paclitaxel-Coated Drug Coated Balloon (LEGFLOW DCB) Treatment versus Uncoated Balloon Angioplas More ... clinical trial medical devices multicentric A1 Dr. med. Amine Chouiter Cardionovum GmbH Hôpital de la Providence, Neuchâtel
INSELSPITAL, Universitätsklinikum Bern, Bern
Service de chirurgie vasculaire, Centre hospitalier universitaire vaudois (CHUV), Service de chirurgie vasculaire
Cent More ...
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Kantonale Ethikkommission Bern 27.03.2023
2022-D0092 Assessing the symptomatic benefit of slow-wave activity reduction using wearables and sensor-based characterization of depression:
a randomized, counter-balanced crossover study
clinical trial medical devices monocentric C2 Dr. Giulia Da Poian ETHZ - Department of Health and Science Technology ETH Zurich, Zurich
Kantonale Ethikkommission Zürich 20.12.2022 Study has ended
2022-D0091 Radio-ablation of malignant primary liver lesions (hepato-cellular carcinoma, HCC), followed by surgical resection (ablate – resect) clinical trial medical devices monocentric C2 MD Alessandra Cristaudi BetaGlue Technologies SpA Ente Ospedaliero Cantonale (EOC) Ospedale Regionale di Lugano – Civico Dipartimento di Chirurgia, Lugano
Comitato etico cantonale Ticino 06.03.2023 Study has ended
2022-D0090 Beurteilung der Sichtbarkeit anatomischer Strukturen der Zähne, des Zahnhalteapparats, der angrenzenden anatomischen Regionen und der Lagebeziehungen in der Weisheitszahnregion durch optimierte Verwen More ... clinical trial medical devices monocentric A1 Dr. Silvio Valdec Universität Zürich Universität Zürich, Zürich
Kantonale Ethikkommission Zürich 22.11.2022
2022-D0087 Simplified meal approach study using hybrid closed-loop insulin delivery in youth and young adults with type 1 diabetes – a randomised controlled two-centre crossover trial clinical trial medical devices multicentric A1 Prof. Dr. med. et Dr. phil. Lia Bally Universitätsklinik für Diabetologie, Endokrinologie, klinische Ernährung und Metabolismus Inselspital Bern Universitätsklinik für Diabetologie, Endokrinologie, klinische Ernährung und Metabolismus, Bern
Abteilung Endokrinologie und Diabetologie, Universitäts-Kinderspital Zürich, Abteilung Endokrinologie u More ...
Kantonale Ethikkommission Bern Kantonale Ethikkommission Zürich 25.11.2022 yes Study has ended
2022-D0086 Prospective Multicenter Confirmatory Clinical Evaluation of Novilase® Interstitial Laser Therapy for the Focal
Destruction of Malignant Breast Tumours ≤15 mm (BR-003)
clinical trial medical devices multicentric A2 Dr Heike Frauchiger-Heuer Novian Health Inc University Hospital Zurich, Zurich
Breast Centre Zurich, Seefeldstrasse 214
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Zürich 22.11.2022
2022-D0085 Physician Initiated Trial Investigating ESAR (EVAR plus Heli-FX EndoAnchors) and FEVAR for the treatment of aortic aneurysms with short infrarenal aortic neck. clinical trial medical devices monocentric A1 Prof Dr med Drosos Kotelis FCRE - Foundation for Cardiovascular Research and Education GmbH Inselspital, Universitätsspital Bern Universitätsklinik für Gefässchirurgie Herz Gefäss Zentrum, Bern
Kantonale Ethikkommission Bern 24.02.2023
2022-D0084 TicIn for the Treatment of coronAry lesioNs with Drug Eluting Balloons clinical trial medical devices monocentric A2 Prof. Dr. Marco Valgimigli Istituto Cardiocentro Ticino Istituto Cardiocentro Ticino, Ente Ospedaliero Cantonale, Lugano
Comitato etico cantonale Ticino 21.10.2022
2022-D0083 IMPACT OF SILICON-BASED FORMULATIONS ON WOUND HEALING OF LASER-INDUCED MICROSCOPIC SKIN LESIONS clinical trial medical devices monocentric A2 Dr. Hans-Joachim Laubach Stratpharma AG HUG, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 09.03.2023 Study has ended
2022-D0080 Retrospective clinical evaluation of nano-hybrid-composite denture teeth SR Phonares II clinical trial medical devices monocentric A1 Dr. med. dent. Ronny Watzke Ivoclar Vivadent AG Ivoclar Vivadent AG, Schaan
Kantonale Ethikkommission Zürich 26.09.2022 Study has ended
2022-D0079 Comparison between the non-powered AEON™ Endostapler and Echelon FLEX™ Powered plus Stapler with regards to the closure of lung tissue after lung resection in the presence of severe lung emphysema: A More ... clinical trial medical devices monocentric A1 Eric Francis Macharia-Nimietz University Hospital of Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 26.10.2022 Study has ended
2022-D0078 Comparison of Flow-Controlled Ventilation with EVONE Tritube and High frequency Jet Ventilation in Patients undergoing Laryngotracheal Surgery clinical trial medical devices monocentric A1 Dr. Gergely Albu HUG HUG, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 24.10.2022
2022-D0077 Stimulations cérébrales non-invasives innovantes dans la réhabilitation des patients atteints d’une lombalgique chronique. clinical trial medical devices monocentric A1 Stéphane Armand Hopitaux Universitaires de Genèves UNIGE HUG, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 14.12.2022