| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-01293 | Quantitative functional brain mapping imaging using Arterial Spin Labelling | non clinical, involving persons | monocentric | A | Prof KO Lovblad | University Hospital of Geneva |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 26.07.2021 | ||||||
| 2021-01292 | GS-US-546-5857 (ENHANCE-2): A Phase 3, Randomized, Open-Label Study Evaluating the Safety and Efficacy of Magrolimab in Combination with Azacitidine versus Physician’s Choice of Venetoclax in Combina More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. / Thomas / Pabst | Gilead Sciences, Inc. |
Inselspital, Berne Universitätsspital Basel, Basel |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.01.2022 | Study has ended | ||
| 2021-01291 | Mesh vs no mesh after incarcerated inguinal hernia requiring bowel resection: Full-service only in selected patients | personal data/biological material | monocentric | Prof. Dr. Antonio Nocito | Kantonspital Baden |
Kanstonsspital Baden, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 05.10.2021 | |||||||
| 2021-01290 | COMPLEX Registry – A prospective COhort study to describe the Management and outcomes of Patients presenting with compLEX and calcified coronary artery disease | non clinical, involving persons | monocentric | A | Prof. Dr. med. Florim Cuculi | Heart Center, Luzerner Kantonsspital |
Heart Center - Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.10.2021 | ||||||
| 2021-01289 | REZUM Water Vapor Therapy under intravenous sedation: the University Hospital Zurich experience | personal data/biological material | monocentric | Dr. med. Etienne Xavier Keller | Klinik für Urologie, USZ |
Klinik für Urologie, USZ, Zürich |
Kantonale Ethikkommission Zürich | 24.05.2022 | |||||||
| 2021-01286 | Cardiovascular and Renal Treatment in Heart Failure Patients with Hyperkalaemia or at High Risk of Hyperkalaemia (CARE-HK in HF Registry) | non clinical, involving persons | multicentric | A | Prof. Otmar Pfister | VIFOR international AG |
Universitätsspital Basel, Basel Luzerner Kantonsspital, Luzern Kantonsspital Aarau AG, Aarau Hôpitaux Universitaires de Genève HUG, Geneve Kantonsspital St. Gallen, St. Gallen Centre Hospitalier Unive More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de More ... | 16.08.2021 | |||||
| 2021-01285 | Simultaneous application of ketamine and lidiocaine during an ambulatory infusion therapy as a treatment option in refractory chronic pain conditions – A retrospective analysis | personal data/biological material | monocentric | Dr. med Tobias Schneider | Department of Anesthesiology University Hospital of Basel |
Department Anästhesie Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.09.2021 | |||||||
| 2021-01284 | Inter-rater and intra-rater reliability of the International Standards to document remaining Autonomic Function after Spinal Cord Injury/Disorder in the sub-acute phase | non clinical, involving persons | monocentric | A | KD Dr.med. Anke Scheel-Sailer | Swiss Paraplegic Centre |
Swiss Paraplegic Centre, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.07.2021 | ||||||
| 2021-01283 | M14-239: Phase 2, Open-Label Safety and Efficacy Study of Telisotuzumab Vedotin (ABBV-399) in Subjects with Previously Treated c-Met+ Non-Small Cell Lung Cancer | clinical trial | drugs | phase 2 | multicentric | C | Dr. David König | AbbVie Inc. |
Universitätsspital Basel - Medizinische Onkologie, Basel Kantonsspital Winterthur - Medizinische Onkologie, Winterthur |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 26.08.2021 | |||
| 2021-01282 | Zusammenhang von Fusshaltung, plantarem Druck und Fussbewegung bei Gesunden und Patienten mit Knie- und Fussbeschwerden während dem Laufen und Gehen (BEFOFA – Better Foot Function Assessment) (Mastert More ... | personal data/biological material | monocentric | Dr. Patric Eichelberger | Berner Fachhoschule |
Berner Fachochschule, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.07.2021 | |||||||
| 2021-01281 | CQBW251B2202 - A randomized, subjects and investigator blinded, placebo controlled parallel group study to assess the mode of action of QBW251 in patients with Chronic Obstructive Pulmonary Disease (C More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Daiana Stolz | Novartis Pharma Schweiz AG |
Universitätsspital Basel, Basel Kantonsspital Basel Land, Liestal Kantonsspital St. Gallen, St. Gallen Universitätsspital Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 29.07.2021 | Study has ended | ||
| 2021-01280 | Retrospektive Analyse der mit Anti-VEGF behandelten Patienten bei diabetischer Netzhauterkrankung, altersbedingter Makuladegeneration und retinalen Venenverschlüssen | personal data/biological material | monocentric | Prof. Dr. Dr. Martin Zinkernagel | Universitätsklinik für Augenheilkunde |
Universitätsklinik für Augenheilkunde, Inselspital, 3010 Bern |
Kantonale Ethikkommission Bern | 26.07.2021 | |||||||
| 2021-01279 | Surgery for deep infiltrating endometriosis, symptoms and outcomes | non clinical, involving persons | multicentric | A | PD Dr. med Sara Imboden |
Frauenklinik, Inselspital Bern, Bern Universitätsspital Basel, Frauenklinik, Basel Frauenklinik, Kantonsspital Aarau AG, Aarau Luzerner Kantonsspital, Endometriosezentrum, Luzern Centro Endometriosi d More ... |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino | 02.11.2021 | ||||||
| 2021-01278 | Congenital and acquired heart diseases in children of Switzerland | personal data/biological material | monocentric | Prof. Dr. med. Christian Balmer | Verein Kinderherzforschung Schweiz |
Verein Kinderherzforschung Schweiz, Zürich |
Kantonale Ethikkommission Zürich | 27.07.2021 | |||||||
| 2021-01277 | Effects of mandibular protrusion on structural and functional features of masticatory muscles, temporomandibular joints and bite force | non clinical, involving persons | monocentric | A | PD Dr. med. Dr. med. dent. Dominik A. Ettlin | Universität Zürich |
Universität Zürich, Zentrum für Zahnmedizin, Zürich |
Kantonale Ethikkommission Zürich | 10.08.2021 | ||||||
| 2021-01275 | Prevalence of ATTR wild type amyloidosis in 1000 consecutive patients with atrial fibrillation (PATAF - Study) | non clinical, involving persons | monocentric | A | Prof. Dr. med Christine Attenhofer Jost | HerzGefässZentrum, Klinik im Park, Hirslanden |
HerzGefässZentrum, Klinik im Park, Hirslanden, Zürich |
Kantonale Ethikkommission Zürich | 09.11.2021 | Study has ended | |||||
| 2021-01274 | Cell-free DNA Fragmentation in preeclampsia | non clinical, involving persons | monocentric | A | PD Tilo Burkhardt | University of Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 23.07.2021 | Study has ended | |||||
| 2021-01273 | Évaluation de différents estimateurs de la fonction rénale chez les patients hospitalisés aux soins intensifs de pédiatrie et de leur influence sur l’adaptation posologique des médicaments. | personal data/biological material | monocentric | Dr Sc Ermindo R. Di Paolo | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.07.2021 | |||||||
| 2021-01271 | Swiss Cancer Registry on Safety and Efficacy of 177Lu-ITG-PSMA-1 Radionuclide Therapy in Prostate Cancer Patients | personal data/biological material | multicentric | Dr. Alin Chirindel | SGNM |
USB, Basel Inselspital, Bern University Hospital, Bern Luzerner Kantonsspital, Luzern Hirslanden Clinic Sankt Anna Lucerne, Luzern Kantonsspital St.Gallen, St.Gallen CHUV, Lausanne University Hospital More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 14.07.2021 | ||||||
| 2021-01270 | Association between gait performance and falls in older, community-dwelling adults: a post-hoc analysis of the DO-HEALTH Basel cohort | personal data/biological material | monocentric | Dr. Stephanie A. Bridenbaugh | University Department of Geriatric Medicine FELIX PLATTER |
University Department of Geriatric Medicine FELIX PLATTER, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.07.2021 | |||||||