| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2021-01269 | Gait performance and cognitive decline in community-dwelling older adults: a post-hoc analysis of the DO-HEALTH Basel cohort | personal data/biological material | monocentric | Dr. med. Stephanie A. Bridenbaugh | Universitäre Altersmedizin FELIX PLATTER |
Universitäre Altersmedizin FELIX PLATTER, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.07.2021 | |||||||
| 2021-01268 | Voxel-based lesion symptom mapping in minor acute ischemic stroke with mild baseline symptoms treated with acute stroke therapy | personal data/biological material | monocentric | PD Dr. med. MSc Mirjam Heldner |
Department of Neurology, Bern |
Kantonale Ethikkommission Bern | 06.01.2022 | ||||||||
| 2021-01266 | Value of monochromatic CT images versus polychromatic conventional CT images for the detection of acute bowel ischemia (ABI) | personal data/biological material | monocentric | Professor Sabine Schmidt Kobbe | CHUV - Radiodiagnostic et |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 26.08.2021 | |||||||
| 2021-01265 | Diagnostic accuracy of regional body composition indices by dual-energy X-ray absorptiometry for lipedema detection: a case-control study in a Swiss University Hospital. | personal data/biological material | monocentric | Ms Lucia Mazzolai | CHUV - Angiologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.10.2021 | Study has ended | ||||||
| 2021-01264 | Alignment in ORIGIN® knee prostheses | non clinical, involving persons | monocentric | A | Prof. Dr. med. Markus P. Arnold | Praxis MEIN KNIE |
Praxis MEIN KNIE, Münchenstein |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.12.2021 | Study has ended | |||||
| 2021-01263 | Patient-and Significant Informal Caregiver-Reported Experience Measures following discharge from the Valais Hospital during the second wave of the COVID-19 pandemic | non clinical, involving persons | monocentric | A | Mrs Nadine Tacchini-Jacquier | Hôpital du Valais |
Valais Hospital, Sion |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.07.2021 | ||||||
| 2021-01262 | Studying the impact of a low carbohydrate diet on the small intestinal microbiota | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Benjamin Misselwitz | Universitätsklinik für Viszerale Chirurgie und Medizin |
Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 19.08.2021 | |||||
| 2021-01261 | Long-term quality of life outcomes after gastric band removal and concomitant gastric bypass: A single centre cohort study. | personal data/biological material | monocentric | med. pract. Matthias Pfister | Kantonsspital Frauenfeld |
STGAG, Kantonsspital Frauenfeld, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 10.06.2021 | |||||||
| 2021-01260 | Health Status and Healthcare Services Utilization among Unaccompanied Asylum-Seeking Minors Settled in Switzerland: Protocol for a Retrospective Cohort Study from a Hospital-based Youth Outpatient Cli More ... | personal data/biological material | monocentric | Dre Magdalini PATSEADOU | Consultation Santé Jeunes, HUG |
Consultation Santé Jeunes, HUG & Institut Universitaire de Médecine de Famille et de l'Enfance (UniGe), Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.08.2021 | |||||||
| 2021-01259 | Abdominal or Transanal TME in Therapy of Rectal Cancer: A Retrospective Cohort Study | personal data/biological material | monocentric | Dr. med. Lukas Marti | Klinik für Chirurgie, Kantonsspital St. Gallen |
Klinik für Chirurgie, Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 14.06.2021 | |||||||
| 2021-01258 | COAV101A12306 - A Phase IIIb, open-label, single-arm, single-dose, multicenter study to evaluate the safety, tolerability and efficacy of gene replacement therapy with intravenous OAV101 (AVXS-101) in More ... | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. med. Andrea Klein | Novartis Pharma Schweiz AG |
Universitäts-Kinderspital beider Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.11.2021 | yes | Study has ended | ||
| 2021-01257 | FaR-RMS: An overarching study for children and adults with Frontline and Relapsed RhabdoMyoSarcoma | clinical trial | drugs | phase 1/2 | multicentric | C | Dr. med. Willemijn Breunis | University of Birmingham |
Universitäts-Kinderspital Zürich, Zürich Inselspital Bern, 3010 Bern Kantonsspital Aarau AG, Aarau Universitäts-Kinderspital beider Basel (UKBB), 4031 Basel Luzerner Kantonsspital, Luzern HUG Hôpitaux More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... | 24.08.2021 | yes | ||
| 2021-01256 | Does kidney transplantation improve survival in the current era in Europe? | personal data/biological material | monocentric | Prof. Patrice Ambühl | ERA-EDTA Registry |
Institute of Nephrology, Zurich |
Kantonale Ethikkommission Zürich | 22.12.2021 | |||||||
| 2021-01255 | A phase II, open label, multicenter study to investigate the efficacy and safety of domatinostat in combination with avelumab in patients with treatment-naïve metastatic Merkel Cell Carcinoma - the ME More ... | clinical trial | drugs | phase 2 | monocentric | C | Prof. Dr. med., Dr. sc. nat. Antonio Cozzio | 4SC AG |
Kantonspital St. Gallen; Klinik für Dermatologie, Venerologie und Allergologie, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 19.07.2021 | Study has ended | |||
| 2021-01254 | Impact de la Iatrogénie médicamenteuse chez les personnes âgées de 75 ans et plus dans le service des Urgences | non clinical, involving persons | monocentric | A | Dr. Francois-Xavier AGERON | CHUV |
Centre Hospitalier Universitaire Vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 21.07.2021 | Study has ended | |||||
| 2021-01253 | Perception des patients et des infirmières d'orthopédie d’être prêts pour le départ de l’hôpital | non clinical, involving persons | monocentric | A | Dr. Sc. Cédric Mabire | UNIL - Proline |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 31.08.2021 | ||||||
| 2021-01252 | MK-3475-B98: A Phase 1b/2 Study to Evaluate the Efficacy and Safety of Pembrolizumab in Combination with Investigational Agents for the Treatment of Participants With PD-1/L1-refractory Extensive-Stag More ... | clinical trial | drugs | phase 1/2 | monocentric | C | Carolin Lips | Merck Sharp & Dohme Corp LLC |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 16.09.2021 | ||||
| 2021-01251 | Development of clinical pupillometry as a tool to grade photoreceptor function for patients with retinal and optic nerve disease | non clinical, involving persons | monocentric | A | Aki Kawasaki | Hôpital ophtalmique |
Hôpital Ophtalmique Jules Gonin, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.08.2021 | Study has ended | |||||
| 2021-01250 | Difference of Spatial Contrast Sensitivity in Patients with Cataract and Healthy Controls | non clinical, involving persons | multicentric | A | Prof. Lucas Bachmann | medignition AG |
medignition AG, Zürich Augenmobil, Zürich Augenarztpraxis Stemmle AG, Zürich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 15.10.2021 | |||||
| 2021-01249 | Comparison of traditional outcome measures and self-assessed goal achievement in patients treated surgically for benign prostatic hyperplasia | personal data/biological material | monocentric | Dr. med. Manolis Pratsinis | Klinik für Urologie |
Klinik für Urologie, Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 17.06.2021 | |||||||