| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01730 | iCHECK: Impact of clonal haematopoiesis on the efficacy of checkpoint inhibition: A retrospective single center analysis. | personal data/biological material | monocentric | Dr. med. Dr. sc. nat. Jeremy Deuel | Universitätsspital Zürich |
Universitätsspital, Zürich |
Kantonale Ethikkommission Zürich | 19.12.2023 | |||||||
| 2023-01727 | International Real-World Study of MET Overexpression in Patients with Non-Small Cell Lung Cancer (METRIX study) | personal data/biological material | monocentric | PD Dr. med. Spasenija Savic Prince | AbbVie AG |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.10.2023 | |||||||
| 2023-01726 | COMPANION DIAGNOSTICS: Measurement of the GSM Phase 1 trial (BP44161) with CSF and blood based biomarker immunoassays - RD006619 | personal data/biological material | monocentric | Ms Geraldine Peeters | Roche Diagnostics GmbH |
Labcorp, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 09.10.2023 | |||||||
| 2023-01724 | Subsartorial Saphenous Nerve Block (SSNB) versus Femoral Nerve Block (FNB) in primary Total Knee Arthroplasty (TKA) combined with Infiltration between Popliteal Artery and Capsule of the Knee (IPACK) More ... | clinical trial | other clinical trials | monocentric | A | Dr. med. Judith Bering | Klinik für Orthopädie und Unfallchirurgie |
Klinik für Orthopädie und Unfallchirurgie Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.10.2023 | |||||
| 2023-01723 | Gibt es einen Zusammenhang zwischen der Dosis, Wirksamkeit, Toxizität und fettfreien Körpermasse von Krebspatienten, die mit Tyrosinkinaseinhibitoren behandelt werden? | personal data/biological material | monocentric | Dr Berna Özdemir | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 24.10.2023 | |||||||
| 2023-01721 |
AMBRA: Assessment of Microstructural Brain Alterations Assessment of myelin content and tissue microstructure in multiple sclerosis: a repeated MRI study |
non clinical, involving persons | monocentric | B | Prof.Dr.med.Dr.phil. Cristina Granziera | Research Center for Clinical Neuroimmunology and Neuroscience RC2NB |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.12.2023 | ||||||
| 2023-01719 | Bland portal vein thrombosis in patients with hepatocellular carcinoma: characteristics, clinical features and response to anticoagulation | personal data/biological material | monocentric | Prof. Annalisa Berzigotti | Insel Gruppe AG |
Insel Gruppe AG, Bern |
Kantonale Ethikkommission Bern | 10.11.2023 | |||||||
| 2023-01718 | Physiological activation measured by EEG during physical effort | non clinical, involving persons | monocentric | A | Petra Susan Hüppi | Hôpitaux Universitaires de Genève |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 11.12.2023 | yes | |||||
| 2023-01717 | M23-698: A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Efficacy and Safety of Upadacitinib in Adult and Adolescent Subjects with Moderate to Severe Hidradenitis Suppurativa More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Reinhard Dummer | AbbVie Inc. |
USZ, Dermatologische Klinik, Zürich Universitätsklinik für Dermatologie, Insel Bern, Bern HUG,Dermatologie et Vénéréologie, Genève KSSG, Klinik für Dermatologie, St.Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission Cantonale d'éthique de la recherche Genève (CCER) | 12.12.2023 | yes | ||
| 2023-01716 | Effects of Intravenous [Pyr1]apelin-13 in Healthy Volunteers with Artificially Induced SIAD and Patients with SIAD – a monocentric randomized double-blind placebo-controlled cross-over study - the esc More ... | clinical trial | other clinical trials | monocentric | B | Prof. Dr. med. Mirjam Christ-Crain | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.11.2023 | |||||
| 2023-01715 | Effect of Glucagon-like peptide-1 receptor agonists (GLP-1 RA) on alcohol consumption, metabolism and liver parameters in patients with obesity and fatty liver disease | clinical trial | drugs | n/a | monocentric | A | Dr. med. Sussana Gomes Rodrigues | Insel Gruppe AG |
Insel Gruppe AG, Bern |
Kantonale Ethikkommission Bern | 11.01.2024 | ||||
| 2023-01714 | Sex disparities in infections after solid organ transplantation – A Swiss Transplant Cohort Study Registry Study | personal data/biological material | monocentric | PD Dr Dr Vanessa Banz |
Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 18.10.2023 | ||||||||
| 2023-01713 | Mécanismes moléculaires de la toxicité de la protéinurie lors de l'insuffisance rénale chronique | personal data/biological material | monocentric | Prof. Sophie de Seigneux |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 19.03.2024 | ||||||||
| 2023-01712 | Longitudinale Analyse von Behandlungsergebnissen beim NSCLC im Stadium III | personal data/biological material | monocentric | PD Dr. Tobias Finazzi | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.12.2023 | |||||||
| 2023-01711 | CLNP023B12001B - An open-label, non-randomized extension study to evaluate the long-term efficacy, safety and tolerability of LNP023 in subjects with C3 glomerulopathy | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Uyen Huynh-Do | Novartis Pharma Schweiz AG |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 06.12.2023 | ||||
| 2023-01710 | Prospective validation of the EBJIS Definition of Periprosthetic Joint Infection | personal data/biological material | monocentric | PD Dr. med | UMC Groningen |
Martin, Clauss |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.09.2023 | |||||||
| 2023-01707 |
Einflussfaktoren auf das Delayed Gastric Emptying und die Lebensqualität nach partieller Duodenopankreatektomie |
personal data/biological material | monocentric | PD Dr. Ignazio Tarantino | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 14.09.2023 | |||||||
| 2023-01706 | Retrospective analysis of outcome in terms of clinical and radiological impact of Gamma Knife radio-neurosurgery for intracranial conditions | personal data/biological material | monocentric | PD Dr Med Constantin Tuleasca | CHUV - BH-08, bureau 635 |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.01.2024 | |||||||
| 2023-01704 | Versorgungsstrategie und Outcome bei Osteosynthese von Extremitätenfrakturen im Mono- und Polytrauma | personal data/biological material | monocentric | Dr. med. Yannik Kalbas | Klinik für Traumatologie, UniversitätsSpital Zürich |
Klinik für Traumatologie, UniversitätsSpital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 01.12.2023 | |||||||
| 2023-01702 | A feasibility single-center, randomized, double-blind, placebo-controlled study to assess the feasibility of conducting a full-scale randomized controlled trial (RCT) assessing efficacy of lactate as More ... | clinical trial | drugs | phase 2 | monocentric | B | Dr Sylfa Fassassi | CHUV - Centre - 11C/01/062 |
Centre hospitalier universitaire vaudois, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.11.2023 | ||||