| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01645 | Hyperoxia during pulmonary rehabilitation in chronic lung disease – does it matter? | clinical trial | other clinical trials | multicentric | A | Prof. Dr. Silvia Ulrich | OST-Ostschweizer Fachhochschule |
Universitätsspital Zürich, Zürich Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 19.12.2023 | ||||
| 2023-01644 | Radiology report explanation and simplification by Large Language Models (LLMs) | personal data/biological material | monocentric | PD Dr. med Andreas hötker |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 07.11.2023 | ||||||||
| 2023-01643 |
A Phase 3b, multi-center, randomized, parallel group, open-label, non-inferiority study evaluating the efficacy, safety, and tolerability of oral dolutegravir/lamivudine once-daily as a first-line More ... |
clinical trial | drugs | phase 3 | multicentric | A | Dr.med. / Marcel / Stöckle | ViiV Healthcare UK Limited |
Universitätsspital Basel, Basel CHECKPOINT Zürich, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 03.01.2024 | |||
| 2023-01642 | International study of patient doses and tissue reactions from fluoroscopy-guided interventional procedures | personal data/biological material | monocentric | Dr. rer. Nat. Gerd Lutters | IAEA |
Kantonssital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.09.2023 | |||||||
| 2023-01641 |
DER KRANIO-ZERVIKALE FLEXIONSTEST, GEMESSEN MIT DER „NOD“ EINE PILOT/MACHBARKEITSSTUDIE |
clinical trial | other clinical trials | monocentric | A | Mr Markus Ernst | Züricher Hochschule für angewandte Wissenschaften |
Zurich University of applied sciences, Winterthur |
Kantonale Ethikkommission Zürich | 03.11.2023 | |||||
| 2023-01639 | Lactobreath: A pilot study to diagnose lactose intolerance based on the exhaled breath metabolome | clinical trial | other clinical trials | monocentric | A | Prof. Daniel Pohl | ETH Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 31.10.2023 | |||||
| 2023-01638 | The effects of Inspiratory Muscle Training on endurance performance in trained athletes under normoxic and hypoxic conditions: A gender-based comprehensive study | clinical trial | other clinical trials | monocentric | A | Dr Grégoire Millet | UNIL |
UNIL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.01.2024 | |||||
| 2023-01637 | GUT - Gastric Ultrasound in Trauma | non clinical, involving persons | monocentric | A | PD Dr.med. Eckhard Mauermann |
Stadtspital Zürich Triemli, Zürich |
Kantonale Ethikkommission Zürich | 01.12.2023 | |||||||
| 2023-01636 |
Retrospektive und prospektive Analyse der bildgebenden und klinischen Daten von Patienten mit spontaner intrakranieller Hypotension (Liquorverlustsyndrom) Retrospective and prospective analysis of More ... |
personal data/biological material | monocentric | PD Dr. med. Tomas Dobrocky | Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie Inselspital Bern |
Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 28.09.2023 | |||||||
| 2023-01635 | Charakterisierung der Tumor-assoziierten Makrophagen in der hämorrhagischen Tumorzellumgebung mittels multidimensionalen Omics-Untersuchungen an solidem Tumor Gewebe | personal data/biological material | monocentric | Florence Vallelian | Klinik und Poliklinik für Innere Medizin |
Klinik für Innere Medizin, Zürich |
Kantonale Ethikkommission Zürich | 31.10.2023 | |||||||
| 2023-01632 | Total Hip Arthroplasty in outpatient care in the swiss healthcare-system, a case series and financial analysis. | personal data/biological material | monocentric | Dr. med. Marco Rohner | Bürgerspital Solothurn |
Bürgerspital Solothurn, Solothurn |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.09.2023 | |||||||
| 2023-01630 | TIAR trial: Trattamento con combinazioni contenenti Immunoterapia in prima linea nei pazienti Affetti da tumore Renale metastatico: analisi retrospettiva di una casistica multicentrica | personal data/biological material | monocentric | Dr. med. Ursula Vogl | Oncologia Medica-Ospedale Ordine Mauriziano |
Instituto Oncologico della Svizzera Italiana, Bellinzona |
Comitato etico cantonale Ticino | 27.11.2023 | |||||||
| 2023-01629 | Expression of cell surface antigens in melanoma patients treated with BRAF/MEK-inhibitor and immune checkpoint inhibitors. | personal data/biological material | monocentric | Dr. med. Vittoria Espeli | Orion Corporation |
Oncology Institute of Southern Switzerland - IOSI, Viganello |
Comitato etico cantonale Ticino | 20.11.2023 | |||||||
| 2023-01628 | Influence of the dietary supplement Luteolin for two weeks on memory in healthy subjects | clinical trial | other clinical trials | monocentric | A | Dr. med. Christiane Gerhards | Universität Basel |
Universität Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.09.2023 | |||||
| 2023-01627 |
A randomized, double-blind, placebo-controlled, multicenter, adaptive phase III trial to investigate the efficacy and safety of vilobelimab in the treatment of ulcerative pyoderma gangrenosum |
clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. med. Dr. sc. nat Alexander Navarini | InflaRx GmbH |
Universitätsspital Basel, Klinik für Dermatologie, 4031 Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.11.2023 | ||||
| 2023-01626 | The influence of humerus rotation osteotomy on humeral head centering in a long-term follow-up | personal data/biological material | monocentric | Prof. Dr. med. univ. Philipp Moroder | Schulthess Klinik |
Schulthess Clinic, Zürich |
Kantonale Ethikkommission Zürich | 12.01.2024 | |||||||
| 2023-01625 | A Phase 1 Open-Label, Multi-Center, Safety and Efficacy Study of PRT2527 as Monotherapy and in Combination with Zanubrutinib in Participants with Relapsed/Refractory Hematologic Malignancies | clinical trial | drugs | phase 1 | monocentric | C | Prof.Dr. med. Anastasios Stathis | Prelude Therapeutics |
EOC Ospedale Regionale di Bellinzona e Valli - San Giovanni Bellinzona, Bellinzona |
Comitato etico cantonale Ticino | 04.12.2023 | ||||
| 2023-01624 | Premature physeal growth arrest in children and adolescents following physeal ankle fractures | personal data/biological material | monocentric | Dr Silvia Valisena | HUG |
Service de chirurgie orthopédique et traumatologie de l’appareil locomoteur, HUG, Genéve |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 11.12.2023 | |||||||
| 2023-01623 | A randomized comparison of the vaginal, vNOTES or total laparoscopic approach for hysterectomy in women with benign gynaecological disease | clinical trial | other clinical trials | monocentric | A | Prof. Daniela Huber | Hôpital du Valais Sion |
Departement of gynecology and obstetrics, Valais Hospitalnd o, Sion |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.02.2024 | |||||
| 2023-01622 | How to achieve success rate with 4-stages ICG angiography in free flaps and pedicle flaps reconstruction | personal data/biological material | monocentric | Prof.Dr.med. Mario F. Scaglioni |
Hospital of Lucerne, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.09.2023 | ||||||||