| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-01058 |
Influence de la résilience sur le déclin cognitif des patients atteints de la maladie d’Alzheimer débutante et d’expériences traumatiques dans l’enfance et l’adolescence: une étude préliminaire cas-c More ... |
non clinical, involving persons | monocentric | A | Armin von Gunten | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.08.2022 | ||||||
| 2022-01056 | ESH ABPM COVID-19 STUDY | personal data/biological material | monocentric | Prof. Grégoire Wuerzner | European Society of Hypertension |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.07.2022 | |||||||
| 2022-01055 | Intrathecal administration of anti-PD1/anti-CTLA-4 in combination with systemic combination of anti-PD1/anti-CTLA-4 in patients with NSCLC without oncogenic driver mutation or melanoma and newly diagn More ... | clinical trial | drugs | phase 1 | multicentric | B | Dr. med. Emilie Le Rhun | University Hospital Zurich |
University Hospital Zurich, Zurich Department of Oncology, Geneva University Hospitals, Geneva Department of Medical Oncology, Kantonsspital St. Gallen, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Commission Cantonale d'éthique de la recherche Genève (CCER) | 02.09.2022 | |||
| 2022-01054 | Analysis of INtestinal dysbiosis and TRanslocation of bacteria and in patients undergoing Abdominal surgery (INTRA Study) | non clinical, involving persons | monocentric | A | Guido Beldi |
Deparmtent for Visceral Surgery and Medicine, Bern |
Kantonale Ethikkommission Bern | 08.07.2022 | |||||||
| 2022-01052 | HIgh frequency Sampling to sTudy the physiological Effect of Probiotics on Peripheral markers of Alzheimer’s pathology: a proof-of-concept study (HISTEPPA) | clinical trial | other clinical trials | monocentric | A | Prof. Giovanni B Frisoni | HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 28.09.2022 | |||||
| 2022-01050 | RETROSPEKTIVE ANALYSE DER THERAPIE VON RETROBULBÄRHÄMATOMEN | personal data/biological material | monocentric | Dr. Dr. Michael Blumer | MKG USZ |
MKG USZ, Zürich |
Kantonale Ethikkommission Zürich | 05.07.2022 | |||||||
| 2022-01049 | Harnweginfektionen nach urodynamischer Diagnostik bei Personen mit neurogener Blasenfunktionsstörung | non clinical, involving persons | monocentric | A | Prof. Dr. med. Jürgen Pannek | Schweizer Paraplegiker-Zentrum |
Schweizer Paraplegiker-Zentrum, Nottwil |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.07.2022 | ||||||
| 2022-01048 | Evaluation of the short- and long-term hearing results in ossicular chain reconstruction, and possible factors influencing hearing outcomes. | personal data/biological material | monocentric | Prof. Dr. med. Th. Linder | Luzerner Kantonsspital |
Kantonsspital, Lucerne |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.06.2022 | |||||||
| 2022-01047 | Prävalenz, klinische Charakteristika und Kostenfolgen des Absetzens von Anti-VEGF bei altersbedingter Makuladegeneration und diabetischem Makulaödem – real-life evidence aus der Schweiz | personal data/biological material | monocentric | Prof. Dr. med. Dr. phil. Michael A. Thiel | Helsana Versicherungen AG |
Augenklinik, Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.08.2022 | |||||||
| 2022-01045 | The epidemiology of cancer in adolescents and young adults (AYAs) in Switzerland | personal data/biological material | multicentric | PD Dr. Ben Spycher | Institute of Social and Preventive Medicine (ISPM), University of Bern |
Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern Department of Health Sciences and Medicine, University of Lucerne, Lucerne |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.09.2022 | ||||||
| 2022-01044 | A prospective randomized, double-blind, placebo-controlled, multi-center phase III study to evaluate the efficacy and safety of mocravimod as an adjunctive and maintenance treatment in adult acute mye More ... | clinical trial | drugs | phase 3 | monocentric | C | Prof. Dr. Michael Medinger | Priothera S.A.S. |
Universitätsspital Basel, Klinik für Hämatologie, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.07.2022 | ||||
| 2022-01042 | Relationships between continuous glucose monitoring and microvascular complications in the retina and the kidney | non clinical, involving persons | monocentric | A | Prof. Dr. Dr. med. Martin Zinkernagel | Inselspital, Bern |
Augenklinik, Inselspital, Bern |
Kantonale Ethikkommission Bern | 20.12.2022 | ||||||
| 2022-01041 |
Decompression of adjacent spinal canal stenosis in primary spondylodesis – A reasonable procedure? |
personal data/biological material | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 05.07.2022 | |||||||
| 2022-01040 | Hospital@Home: Improving Discharge-Management of Complex and Multimorbid Patients | clinical trial | other clinical trials | monocentric | A | Prof. Maria Wertli | Kantonsspital Baden AG |
Kantonsspital Baden AG, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.09.2022 | |||||
| 2022-01039 | Clinical outcome after surgical resection of hallux sesamoid osteomyelitis | personal data/biological material | monocentric | PD Dr. med. Martin Berli | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 03.08.2022 | |||||||
| 2022-01038 | The effect of oral iron supplements on serum hepcidin, insulin and glucose metabolism in pregnancy | clinical trial | other clinical trials | monocentric | A | PhD / Nicole / Stoffel |
ETH Zurich, Zurich |
Kantonale Ethikkommission Zürich | 18.10.2022 | ||||||
| 2022-01037 |
Evaluation of Amphiregulin expression by immunohistochemistry in intestinal tissue samples of patients with acute Graft-versus-Host-Disease after allogeneic hematopoietic cell transplantation |
personal data/biological material | monocentric | Dr. med. Daniel Drozdov | Universitätskinderspital Zürich |
Universitätskinderspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 01.07.2022 | |||||||
| 2022-01034 |
A PHASE 4, SEQUENTIAL RANDOMIZED, OPEN LABEL, MULTICENTER PROSPECTIVE COMPARATIVE STUDY TO EVALUATE THE TREATMENT OF ATRIAL FIBRILLATION IN PRESERVED CARDIAC FUNCTION HEART FAILURE (TAP-CHF TRIAL) |
clinical trial | other clinical trials | monocentric | B | Pr Dipen SHAH | Electrophysiology Research Foundation |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 05.10.2022 | |||||
| 2022-01033 | Romiplostim for thrombocytopenia induced by lomustine at first progression of MGMT promoter-methylated glioblastoma: a randomized phase II open label multicenter study | clinical trial | drugs | phase 2 | multicentric | C | Dr. Patrick Roth | European Organisation for Research and Treatment of Cancer (EORTC) |
UniversitaetsSpital Zurich - Neurology Clinic, Zurich Oncology Institute of Southern Switzerland - Ospedale San Giovanni, Bellinzona |
Kantonale Ethikkommission Zürich | Comitato etico cantonale Ticino | 15.11.2022 | Study has ended | ||
| 2022-01032 | Which role plays Math Anxiety for the development of numerical learning disorders? Investigation of the behavioral and neural correlates of negative emotional effects related to numeracy in children | non clinical, involving persons | monocentric | A | PD Dr. sc. nat. Karin Kucian | University Children's Hospital Zurich, Zentrum für MR-Forschung |
University Children's Hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 10.01.2023 | yes | |||||