| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2020-00838 |
RISK OF DEVELOPING ANTIPHOSPHOLIPID ANTIBODIES FOLLOWING VIRAL INFECTION WITH SARS-COV-2 |
personal data/biological material | monocentric | PD Dr. Bernhard Gerber | Oncology Institute of Southern Switzerland |
Oncology Institute of Southern Switzerland, Bellinzona |
Comitato etico cantonale Ticino | 15.04.2020 | |||||||
| 2020-00837 | A Phase 1, First-in-Human, Multicenter, Open-label, Dose-escalation Study of IPH5201 as Monotherapy or in Combination with Durvalumab ± Oleclumab in Advanced Solid Tumors | clinical trial | drugs | phase 1 | monocentric | C | Dr Martina Imbimbo | MedImmune, LLC, a wholly owned subsidiary of AstraZeneca PLC |
UNIL-CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.07.2020 | Study has ended | |||
| 2020-00836 | First in Human Study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and preliminary efficacy of PPSGG (PN-1007) in anti-MAG neuropathy patients | clinical trial | drugs | phase 1/2 | monocentric | C | Prof. Thierry Kuntzer | Polyneuron Pharmaceuticals AG |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 20.10.2020 | Study has ended | |||
| 2020-00835 | PRESENTATION CLINIQUE ET LIEN EPIDEMIOLOGIQUES DES ENFANTS INFECTES PAR COVID-19 A GENEVE | non clinical, involving persons | monocentric | A | Dr Arnaud L'Huillier | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genéve |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 17.04.2020 | yes | |||||
| 2020-00834 | Which Approach? – Deep Learning Recommendation System for Neurosurgical Craniotomies | personal data/biological material | monocentric | Dr. med. Michael Murek | Universitätsklinik für Neurochirurgie |
Universitätsklinik für Neurochirurgie, Bern |
Kantonale Ethikkommission Bern | 29.07.2020 | Study has ended | ||||||
| 2020-00833 | Accuracy and benefits of guided jaw bone biopsy using a tooth-supported printed drilling template: a retrospective clinical study. | personal data/biological material | monocentric | Dr. Silvio Valdec | Zentrum für Zahnmedizin der Universität Zürich |
Zentrum für Zahnmedizin der Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 30.04.2020 | |||||||
| 2020-00832 | Lower limb total joint replacements improve the quality-adjusted life years in patients who exceed their estimated life expectancy | personal data/biological material | monocentric | Prof Julien Wegrzyn | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.06.2020 | Study has ended | ||||||
| 2020-00830 | COVID-19 infections in people with Primary Ciliary Dyskinesia | non clinical, involving persons | monocentric | A | Prof. Claudia Kuehni | Institute of Social and Preventive Medicine, University of Bern |
Institute of Social and Preventive Medicine, University of Bern, Bern |
Kantonale Ethikkommission Bern | 17.06.2020 | yes | |||||
| 2020-00829 | Sonographic assessment of features suspicious of uterine sarcoma. Evaluation of their use in preoperatvive prediction of malignancy | personal data/biological material | monocentric | Prof. Dr. Viola Heinzelmann-Schwarz |
Frauenklinik, Universitätsspital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.04.2020 | ||||||||
| 2020-00828 | Lungscape 006 – TMB, Validating the prognostic value of tumour mutational burden (TMB) in NSCLC tumours from the ETOP Lungscape cohort | personal data/biological material | multicentric | Prof. Dr. Lukas Bubendorf | ETOP |
Universitätsspital, Basel Universitätsspital Zürich, Institut für Pathologie und Molekularpathologie, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 19.06.2020 | Study has ended | |||||
| 2020-00827 | Hospital-based surveillance of SARS-CoV-2/COVID-19 cases in Switzerland | personal data/biological material | multicentric | Prof Olivia Keiser | Université de Genève - on behalf of FOPH |
Université de Genève, Genève Inselspital Bern, Bern Luzern Children's Hospital, Luzern University Hospital Basel, Basel University of Basel Children's Hospital (UKBB), Basel Cantonal Hospital Aarau, A More ... |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 07.05.2020 | ||||||
| 2020-00825 | Criteria to predict mid-term outcome after stenting of chronic iliac vein obstruction | personal data/biological material | monocentric | Dr. med. Ulrike Hügel | Inselspital |
Universitätsklinik für Angiologie, Bern |
Kantonale Ethikkommission Bern | 17.11.2020 | Study has ended | ||||||
| 2020-00824 | Vertikale Wurzelfrakturen nach apikaler Chirurgie (Wurzelspitzenresektion) – Analyse der möglichen Risikofaktoren | personal data/biological material | monocentric | Prof. Dr. med. dent. Thomas von Arx |
Klinik der Oralchirurgie und Stomatologie, Zahnmedizinische Kliniken Bern, 3010 |
Kantonale Ethikkommission Bern | 07.07.2020 | ||||||||
| 2020-00823 |
The EPICENTRE (ESPNIC Covid pEdiatric Neonatal Registry) initiative. A multidisciplinary initiative for an international SARS-CoV-2 infections registry |
non clinical, involving persons | multicentric | A | Prof. Peter Rimensberger | Hôpitaux universitaires de Genève |
Hôpitaux Universitaires de Genève, Geneva Kantonsspital, St. Gallen Centre hospitalier universitaire vaudois, Lausanne Kinderspital Zürich, 8032 Zürich Kantonsspital Graubünden, Chur |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 16.04.2020 | yes | ||||
| 2020-00821 | Assessment of the Humoral Immunopathology in COVID-19 Patients | personal data/biological material | monocentric | Prof. Dr. Lukas Flatz |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 09.04.2020 | ||||||||
| 2020-00820 | Efficacy of early hydroxychloroquine in outpatients to reduce secondary hospitalisation and household transmission of SARS-CoV-2 infection in Switzerland. A double-blind, randomised, placebo-controll More ... | clinical trial | drugs | phase 3 | multicentric | B | Prof. Blaise Genton | Unisanté |
Unisanté, Lausanne Universitätsklinik für Infektiologie, Inselspital, Bern Berner Institut für Hausarztmedizin, Bern Kantonsspital Aarau, Aarau University of Fribourg, Fribourg SMVS, Sion |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 22.04.2020 | yes | Study has ended | |
| 2020-00819 | COVIDAge study – Hôpital des Trois-Chêne | personal data/biological material | monocentric | Aline Mendes | Geneva University Hospitals |
Geneva University Hospitals, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.04.2020 | |||||||
| 2020-00818 | An international randomised trial of additional treatments for COVID-19 in hospitalised patients who are all receiving the local standard of care | clinical trial | drugs | phase 3 | multicentric | C | PD Dr Oriol Manuel | Organisation Mondiale de la Santé (OMS) |
CHUV, Service des maladies infectieuses, Lausanne Insel Gruppe AG, Inselspital, Bern Campus SLB Lindenhofgruppe, Bern Kantonsspital Aarau, Aarau Solothurner Spitäler AG, Kantonsspital Olten, Olten Hôp More ... |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Co More ... | 15.04.2020 | Study has ended | ||
| 2020-00817 | ENDOSCOPIC CHARACTERISATION OF INFLAMMATORY ACTIVITY IN EOE: COMPARISON OF STANDARD IMAGING WITH HIGH MAGNIFICATION TO THE GOLDSTANDARD HISTOLOGY – A MONOCENTRIC, OBSERVATIONAL STUDY (ENDOSCOPIC CHARA More ... | clinical trial | medical devices | monocentric | A1 | Dr. med. Bernhard Morell | Department of Gastroenterology and Hepatology, University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 30.04.2020 | Study has ended | ||||
| 2020-00816 | COVID-19 in Baselland: Investigation and Validation of Serological Diagnostic Assays and Epidemiological Study of Sars-CoV-2 specific Antibody Responses (SERO-BL-COVID-19) | non clinical, involving persons | monocentric | A | Miodrag Savic | Department of Health, Economics and Health Directorate Canton Basel-Land |
Department of Health, Economics and Health Directorate Canton Basel-Land, Liestal |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.06.2020 | ||||||