| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2018-00730 | Biomechanical proof of concept for intramedullary screw fixation compared to dorsal plating in metacarpal shaft fractures | deceased persons | monocentric | PD Dr. med. Maurizio Calcagni | Universitätsspital Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 25.05.2018 | |||||||
| 2018-00729 | Personalized analysis of breast cancer ex vivo and in vivo | non clinical, involving persons | multicentric | A | Prof. Dr. Mohamed Bentires-Alj | University Hospital of Basel |
University Hospital Basel, Basel Brustzentrum Bern Biel/Hirslanden Salem-Spital, Bern Breast Center Inselspital, Universitätsspital Bern, Bern Hopital du Jura, Delemont Kantonsspital Baselland, Liesta More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 13.08.2018 | |||||
| 2018-00728 | BRAIN SHIFT COMPENSATION | personal data/biological material | monocentric | Prof. Dr Raphael Guzman | Neurochirurgie Universitätsspiatal |
Universitätsspital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.05.2018 | Study has ended | ||||||
| 2018-00727 | Effect of Direct Acting Antiviral Drugs on the Occurence and Recurrence of Intra- and Extrahepatic Malignancies in Patients with Chronic Hepatitis C. | personal data/biological material | multicentric | Prof. Annalisa Berzigotti | Inselspital |
UVCM Hepatologie, 3008 Bern Universitätsspital Basel, Basel Kantonsspital St. Gallen, St. Gallen Epatocentro Ticino, Lugano CHUV, Lausanne Hôpital Neuchâtelois, Neuchâtel USZ, Zürich |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), More ... | 03.07.2018 | Study has ended | |||||
| 2018-00726 | MK-3475-689: A Phase III, Randomized, Open-label Study to Evaluate Pembrolizumab as Neoadjuvant Therapy and in Combination With Standard of Care as Adjuvant Therapy for Stage III-IVA Resectable Locore More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Tamara Rordorf | Merck Sharp & Dohme LLC. |
UniversitätsSpital Zürich, Zürich Hôpitaux Universitaires de Genève, Genève Ospedale San Giovanni, Bellinzona |
Kantonale Ethikkommission Zürich | Commission Cantonale d'éthique de la recherche Genève (CCER), Comitato etico cantonale Ticino | 07.12.2018 | |||
| 2018-00725 | Appropriateness of Statin use in multimorbid, elderly patients - a cross sectional cohort study nested in a multicentre randomized trial | personal data/biological material | monocentric | Prof. Dr. Nicolas Rodondi | Klinik und Poliklinik für Allgemeine Innere Medizin |
Klinik für Allgemeine Innere Medizin, Bern |
Kantonale Ethikkommission Bern | 03.07.2018 | |||||||
| 2018-00724 | Natural orifice transluminal endoscopic surgery: Outcome Analysis of 569 transvaginal cholecystectomies | personal data/biological material | monocentric | Prof. Dr. med. Antonio Nocito | Kantonsspital Baden |
Kantonsspital Baden, Department of Surgery, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.05.2018 | |||||||
| 2018-00723 | Ist die prophylaktische Gabe eines niedermolekularen Heparins 48 Stunden nach Schädel-Hirn-Trauma sicher? Eine retrospektive Beobachtungsstudie | personal data/biological material | monocentric | Martina Jäggi | Kantonsspital Winterthur |
Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | 25.05.2018 | |||||||
| 2018-00722 | Scarf-Akin osteotomy for hallux valgus deformity: A retrospective study in XXX feet | personal data/biological material | monocentric | Dr.med Cristopher Lenz | Kantonsspital Baden |
Kantonsspital Baden, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.05.2018 | |||||||
| 2018-00720 |
(20130193) A Postmarketing Prospective Cohort Study of Melanoma Patients Treated With IMLYGIC® (Talimogene Laherparepvec) in Clinical Practice to Characterize the Risk of Herpetic Infection Among Pat More ... |
non clinical, involving persons | multicentric | A | Prof. Dr. med Reinhard Dummer | Amgen |
Universitätsspital Zürich, Zürich Universitätsspital Basel, Basel Kantonsspital Graubünden, Chur |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 06.07.2018 | |||||
| 2018-00719 | Phase III confirmatory efficacy and safety trial of remimazolam (CNS7056) compared with propofol for intravenous anaesthesia during elective surgery | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Donat R. Spahn | PAION UK Limited |
UniversitätsSpital Zürich Institut für Anästhesiologie, Zürich University hospitals Genève, Geneve Kantonspital Winterthur, Institue for Anesthesiology, Winterhur Stadtspital Triemli, Zurich |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.11.2018 | Study has ended | ||
| 2018-00718 | Pembrolizumab in association with the Multipeptide vaccine IMA950 adjuvanted with Poly-ICLC for relapsing Glioblastoma: a randomized phase I/ II trial | clinical trial | drugs | phase 1/2 | monocentric | C | Prof. Denis Migliorini | HUG |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 18.09.2018 | Study has ended | |||
| 2018-00717 | The influence of aerobic exercise or relaxing therapy combined with dance movement therapy on balance, gait and body schema in Parkinson's patients. | clinical trial | other clinical trials | monocentric | A | Dr. Clare Maguire | Billdungszentrum Gesundheit Basel Stadt |
BZG Münchenstein, Münchenstein |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.05.2018 | |||||
| 2018-00715 | Discrepancy in reporting of perioperative complications | personal data/biological material | monocentric | PD Dr Salome Dell-Kuster | Department of Anesthesiology University Hospital Basel |
University Hospital Basel, Basel, Switzerland |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.05.2018 | |||||||
| 2018-00714 | Kontrastmittelverstärkte Magnetresonanztomographie von venösen Malformationen in Korrelation mit der intraoperativen Angiographie: Voraussage bezüglich venösem Abfluss | non clinical, involving persons | monocentric | A | Ralph Gnannt |
Kinderspital, Zürich |
Kantonale Ethikkommission Zürich | 20.06.2018 | yes | ||||||
| 2018-00713 | Identification of specific protein and metabolite patterns in the blood and urine of patients with reduced renal function. | non clinical, involving persons | monocentric | A | Dr. med. Lyubov Chaykovska | Medenty Ltd |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 03.07.2018 | Study has ended | |||||
| 2018-00712 | Characterization of human intestinal macrophages in metabolic disease – iMAC (pilot) study | non clinical, involving persons | monocentric | A | PD Dr. med. Claudia Cavelti-Weder | University Hospital Basel |
University Hospital Basel, Department of Endocrinology, Diabetes and Metabolism, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 14.05.2018 | ||||||
| 2018-00711 | Evaluating associations between facial asymmetry detected in three-dimensional facial photographs and clinical findings of patients with juvenile idiopathic arthritis. | personal data/biological material | monocentric | PD Dr. Dr. Raphael Patcas | Klinik für Kieferorthopädie und Kinderzahnmedizin |
University of Zurich, Clinic for Orthodontics, Zürich |
Kantonale Ethikkommission Zürich | 27.04.2018 | |||||||
| 2018-00710 | Evaluation of the evolution of hearing performance among adult cochlear implantation recipients : individual needs and indications for speech therapy. | clinical trial | other clinical trials | monocentric | A | Dre. Angélica Pérez-Fornos |
Centre Hospitalo-Universitaire Romand d’Implantations Cochléaires (CHURIC), Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.08.2018 | Study has ended | |||||
| 2018-00709 | Subjective evaluation of a sound externalization method in remote microphone systems for binaural hearing aids with respect to auditory distance perception | clinical trial | medical devices | monocentric | C | Dr Gilles Courtois | Sonova AG |
Ecole Polytechnique Fédérale de Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 18.09.2018 | Study has ended | ||||