| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-02138 | Longitudinal assessment of the Edinburgh Cognititve and Behavioural Amyotrophic Lateral Sclerosis screen (ECAS), version A, B and C | non clinical, involving persons | monocentric | A | Oleksandra Hoptar | HOCH Health Ostschweiz, Kantonsspital St. Gallen Kantonsspital St. Gallen, Muskelzentrum/ALS Clinic |
HOCH Health Ostschweiz, Kantonsspital St. Gallen, Muskelzentrum/ALS Clinic, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 23.10.2025 | ||||||
| 2025-02137 | A 52-week, Multicenter, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study of Nemolizumab in Adult Patients with Systemic Sclerosis | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. Dr. med. Muriel Elhai | Galderma S.A. |
Universitätsspital Zürich, Zurich HOCH Health Ostschweiz, Kantonsspital St. Gallen, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS) | 09.01.2026 | |||
| 2025-02136 | A Phase 1, Open-Label, Multicenter Study of INCB160058 in Participants With Myeloproliferative Neoplasms | clinical trial | drugs | phase 1 | multicentric | C | Prof. Dr. med. Sara Meyer | Incyte Corporation |
INSELSPITAL - Universitätsspital Bern, Bern Universitätsspital Zurich, Zurich |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 16.02.2026 | |||
| 2025-02133 | Clinicogenomic prediction modelling in pancreatic cancer – an explorative retrospective cohort study | personal data/biological material | monocentric | Dr. med. Christoph Kümmerli | Clarunis Universitäres Bauchzentrum Basel |
Clarunis Universitäres Bauchzentrum Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.12.2025 | |||||||
| 2025-02132 | Distribution patterns of mucosal melanocytes in the sinonasal mucosa | non clinical, involving persons | monocentric | A | PD Dr. med. Christian Meerwein | ORL-Klinik Universitätspital Zürich |
Universitätsspital Zürich, Orl-Klinik, Zürich |
Kantonale Ethikkommission Zürich | 17.02.2026 | ||||||
| 2025-02131 |
Stress shielding patterns and risk factors in anatomic total shoulder arthroplasty |
personal data/biological material | monocentric | PhD Dr. med. Matthijs Jacxsens | HOCH Health Ostschweiz |
HOCH Health Ostschweiz, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 23.10.2025 | |||||||
| 2025-02130 | Retrospektive Evaluation dedizierter, mit Beschleunigung akquirierter und mit Hilfe künstlicher Intelligenz rekonstruierter, klinisch routinemässig eingesetzter MR-Sequenzen bei Kindern | personal data/biological material | monocentric | PD Dr. Selma Sirin | Kinderspital Zürich - Eleonorenstiftung |
Kinderspital Zürich - Eleonorenstiftung, Zürich |
Kantonale Ethikkommission Zürich | 18.12.2025 | |||||||
| 2025-02127 |
Tige Fémorale Modulaire, Conique, Cannelée, Non Cimentée (Restoration Stryker®) avec Cupule Hémisphérique à Double Mobilité (Symbol, Dedienne Santé ®) dans les révisions de PTH: Survie d’implant à More ... |
personal data/biological material | monocentric | Prof. Julien Wegrzyn | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.10.2025 | |||||||
| 2025-02125 | Multivendor validation of AI tools for pediatric musculoskeletal radiographic measurements | personal data/biological material | monocentric | PD Dr. med. Michelle Seiler | University Children's Hospital Zurich |
University Children's Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 23.01.2026 | |||||||
| 2025-02124 | Investigating the link between SKAP2 genetic locus associated with an increased risk of Inflammatory Bowel Disease and the inflammatory responses of T lymphocytes in the gut | non clinical, involving persons | monocentric | A | Prof. Petr Hruz | Clarunis |
Clarunis, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.02.2026 | ||||||
| 2025-02123 | Effect of Cochlear Implant Stimulation on Spatial Orientation in Adult Users | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Georgios Mantokoudis | Inselspital Bern |
Universitätsklinik für Hals-, Nasen- und Ohrenkrankheiten, Kopf- und Halschirurgie, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 20.01.2026 | |||||
| 2025-02121 | Effectiveness of Eccentric Cycling Exercise in Ambulatory Rehabilitation for Patients with Cardiopulmonary Diseases: A Pragmatic Randomized Controlled Trial | clinical trial | other clinical trials | monocentric | A | Prof. Silvia Ulrich | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 20.02.2026 | |||||
| 2025-02120 | Vacuum Bell Therapy as a Non-Surgical Alternative for Pectus Excavatum: Real-World Experience | personal data/biological material | monocentric | Dr. med. Konstantinos Gioutsos | Thoracic Surgery |
Inselspital, Bern University Hospital, Bern |
Kantonale Ethikkommission Bern | 14.11.2025 | |||||||
| 2025-02119 | HERePRO, a Research Project to investigate real-world data of trastuzumab deruxtecan (Enhertu) treatment in different advanced or metastasized cancer indications with HER2+ mutation in comparison to h More ... | non clinical, involving persons | multicentric | A | Prof. Dr. Andreas Trojan | mobile Health AG |
See-Spital, Horgen HOCH Health Ostschweiz, Kantonsspital St.Gallen, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS) | 03.03.2026 | |||||
| 2025-02116 | Adaptive, Phase 2/3, Randomized, Double-Blind Trial Investigating the Efficacy and Safety of Visugromab versus Placebo in Patients with Cancer-associated Cachexia (Visugromab in Cachexia International More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. David Blum | CatalYm GmbH |
Universitäts Spital Zürich, Zürich HOCH Health Ostschweiz, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS) | 20.01.2026 | |||
| 2025-02114 | Tracheostomy after bilateral lung transplantation: timing impact on short- and long-term outcomes in a retrospective single center cohort | personal data/biological material | monocentric | Prof. Thorsten Krueger | CHUV - Chirurgie Thoracique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.10.2025 | |||||||
| 2025-02113 | Retrospektive Outcome-Analyse erwachsener Patienten nach allogener Stammzelltransplantation am Luzerner Kantonsspital 2014-2023 | personal data/biological material | monocentric | Lucas Simeon | LUKS Spitalbetriebe AG |
Luzerner Kantonsspital LUKS, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.11.2025 | |||||||
| 2025-02109 | Pacing Advancements with Cost and Experience VALuation for Unified Patient-Led Clinical Evidence - the PACEVALUE Study | non clinical, involving persons | monocentric | A | Prof. Dr. Dr. med. Andreas Häberlin | Inselspital Bern |
Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 03.02.2026 | ||||||
| 2025-02108 | FEASIBILITY OF SUBJECTIVE REFRACTION MEASUREMENT WITH LIGHTFIELD TECHNOLOGY – STUDY II | non clinical, involving persons | monocentric | A | Prof. Dr. Daniela Nosch | Institut für Optometrie, FHNW |
Institut für Optometrie, Hochschule für Technik, FHNW, 4600 Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.11.2025 | ||||||
| 2025-02107 | Clinically Integrated Multimodal Hip Preservation with Deep Learning Algorithms for Surgical Planning | personal data/biological material | monocentric | Dr. Sebastiano Caprara | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, 8008 Zürich |
Kantonale Ethikkommission Zürich | 20.02.2026 | |||||||