| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01995 |
Development of a screening algorithm for pathogenic gene fusions from whole slide images of lung adenocarcinoma |
personal data/biological material | multicentric | Professor Bubendorf | F. Hoffman-La Roche Ltd. |
University of Basel, Basel University of Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 07.11.2023 | ||||||
| 2023-01994 | Long-term clinical outcome of patients with head and neck cancer treated with pencil beam scanning proton therapy | personal data/biological material | monocentric | PD Dr.med. Barbara Bachtiary | Center for Proton Therapy at Paul Scherrer Institut |
Center for Proton Therapy at Paul Scherrer Institut, Villigen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.11.2023 | |||||||
| 2023-01993 | Arterial tortuosity in non-atherosclerotic vascular diseases | personal data/biological material | monocentric | Prof.Lucia Mazzolai | CHUV - Coeur-vaisseaux |
Department of Angiology, Lausanne University Hospital (CHUV), Switzerland, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.11.2023 | |||||||
| 2023-01992 | Impact of molecular HLA mismatch scores on the incidence of renal allograft outcomes | personal data/biological material | monocentric | Prof. Stefan Schaub |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.11.2023 | ||||||||
| 2023-01991 | Companion Diagnostics: An interventional, prospective IVD device study for the testing of DNA extracted from tumor tissue biopsy samples in a first line setting from patients diagnosed with metastatic More ... | personal data/biological material | monocentric | Ms. Nathalie Philippe | Qiagen Manchester Ltd Citylabs 2.0 |
Labcorp CLS, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.11.2023 | |||||||
| 2023-01990 | Association of pH and oral health: A prospective single-center study | non clinical, involving persons | monocentric | A | Prof. Dr.Tim Joda, phD | Entoothiast AG |
University of Zurich, Clinic of Reconstructive Dentistry, Zürich |
Kantonale Ethikkommission Zürich | 02.02.2024 | ||||||
| 2023-01986 | "Technical advancements of endoscopy – a minimal invasive approach to the spine" | deceased persons | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 23.01.2024 | |||||||
| 2023-01984 | Retrospektive Studie zu den Ursachen von Hyperleukozytose | personal data/biological material | monocentric | Prof. Alicia Rovo | Inselspital |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 19.12.2023 | |||||||
| 2023-01982 | Evaluation der Qualität von Mammographien und der Detektion von Läsionen mit den aktuellen Methoden der Bildgebung der Brust: Eine retrospektive Evaluation | personal data/biological material | monocentric | Dr. med. Noemi Schmidt | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.03.2024 | |||||||
| 2023-01981 |
61Cu-NODAGA-LM3 PET/CT for the Detection of Neuroendocrine Tumors: The COPPER PET in NET Study A prospective, open-label, randomized, controlled, single centre, phase I/II PET/CT study |
clinical trial | drugs | phase 1/2 | monocentric | C | Dr. Guillaume Nicolas | Universitätsspital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 13.03.2024 | ||||
| 2023-01980 | Noninvasive Positive Pressure Ventilation during Neonatal Nasal Intubation | non clinical, involving persons | monocentric | A | PD Dr. med. Christoph Rüegger | University Hospital Zurich |
University Hospital Zürich, Department of Neonatology, Zurich |
Kantonale Ethikkommission Zürich | 26.01.2024 | yes | |||||
| 2023-01979 | Impact of ADHD severity on electrophysiological, neuropsychological and clinical symptom reduction after neurofeedback sessions | non clinical, involving persons | monocentric | A | Ms. Aurélie Reymond-Delacrétaz | Les Toises |
Les Toises, Bienne |
Kantonale Ethikkommission Bern | 25.01.2024 | ||||||
| 2023-01977 | Efficacy and safety of SAR441344 in the treatment of Systemic Lupus Erythematosus: A randomized, double blind, placebo-controlled, Phase 2, proof of concept study | clinical trial | drugs | phase 2 | monocentric | C | Prof. Dr. med Andrea Rubbert-Roth | Sanofi-Aventis Recherche & Développement |
Kantonsspital St Gallen, Klinik für Rheumatologie, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 21.12.2023 | ||||
| 2023-01975 | Retrospective analysis of patients with Parkinson`s Disease undergoing Deep Brain Stimulation (DBS) to determine predictive factors of postoperative clinical efficacy of stimulation. | personal data/biological material | monocentric | PD Dr.med. Andreas Nowacki | Universitätsklinik für Neurochirurgie |
Universitätsklinik für Neurochirurgie, Bern |
Kantonale Ethikkommission Bern | 16.01.2024 | |||||||
| 2023-01974 | Impact of Tenofovir disoproxil fumarate/Emtricitabine (TDF/FTC) on the gut microbiome and microbiome-mediated toxicity of TDF/FTC in men using event-based HIV Pre-Exposure prophylaxis | non clinical, involving persons | multicentric | A | Dr. med. Julia Notter | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, St. Gallen Universitätsklinik für Infektiologie, Inselspital, Bern |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Bern | 16.11.2023 | |||||
| 2023-01973 | Schlafqualität bei Herzinsuffizienzpatienten mit akuter Dekompensation im Vergleich zu anderen chronischen Erkrankungen | non clinical, involving persons | monocentric | A | PD Dr. med. Nisha Arenja | Kantonsspital Olten |
Kardiologie Kantonsspital Olten, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.12.2023 | ||||||
| 2023-01972 | Vergleich von Osteosyntheseplatten zur Versorgung einer 3-Fragment-Fraktur des proximalen Humerus | deceased persons | monocentric | Prof. Dr. Daniel Baumgartner | Bonebridge AG |
ZHAW, Winterthur |
Kantonale Ethikkommission Zürich | 09.01.2024 | |||||||
| 2023-01971 | Evaluation of a seroneutralization test for Tick Borne Encephalitis Virus based on Reporter Viral Particles | personal data/biological material | monocentric | Dr Valeria Cagno | Institut de microbiologie |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 11.12.2023 | |||||||
| 2023-01970 | Prediction of local recurrence after thermo-ablation of hepatocellular carcinoma: deep learning and radiomics prediction model. | personal data/biological material | monocentric | Dr Naïk Vietti Violi | CHUV - Radiodiagnostic et |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 14.03.2024 | |||||||
| 2023-01968 | Correlational analysis of PTEN expression status in prostate carcinoma during disease progression, metastases and castration resistance (Masterarbeit) | personal data/biological material | monocentric | Prof. Dr. Lukas Bubendorf | Institut für medizinische Genetik und Pathologie, USB |
Institut für medizinische Genetik und Pathologie, USB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.11.2023 | |||||||