BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2016-01913 Identification of subjects with lysosomal acid lipase deficiency in a large cohort of hyperlipidemia patients in Switzerland
non clinical, involving persons monocentric A Prof. A. R. Miserez diagene GmbH diagene GmbH, Reinach
Ethikkommission Nordwest- und Zentralschweiz EKNZ 06.02.2017
2016-01912 Aortic Dissection Study –identifying preoperative risk factors for occurrence, long term follow up and comparison of the current predictive scores.


personal data/biological material monocentric PD Dr Denis Berdajs Herzchirurgie Universitätspital, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 09.02.2017
2016-01911 Outcome of a novel surgical technique using antegrade stent implantation during standard repair of acute type a aortic dissection. personal data/biological material monocentric Professor Peter Matt University Hospital Basel Cardiac Surgery, University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 05.03.2018
2016-01910 Facilitation through Aggrastat or cangrelor Bolus and infusion Over prasugreL: a mUlticenter randomized open-label trial in patientS with ST-elevation myocardial inFarction referred for primAry percut More ... clinical trial drugs phase 4 monocentric A Prof. Dr. Marco Valgimigli University Clinic for Cardiology University Clinic for Cardiology Inselspital, 3010 Bern
Kantonale Ethikkommission Bern 26.01.2017 Study has ended
2016-01909 Accuracy of patient specific template-guided vs. free-hand fluoroscopically controlled pedicle and lateral mass screw placement in the subaxial cervical spine: a randomized cadaveric study deceased persons monocentric PD Dr. med. MPH Mazda Farshad Universitätsklinik Balgrist Universitätsklinik Balgrist, Zürich
Ethikkommission Nordwest- und Zentralschweiz EKNZ 15.12.2016 Study has ended
2016-01908 Identifikation von Biomarkern für krankheitsbedingte Komplikationen bei Patienten mit myeloproliferativen Neoplasien personal data/biological material monocentric Dr. med. Alexandre Theocharides University Hospital Zurich, Division of hematology University Hospital Zurich, Division of hematology, Zurich
Kantonale Ethikkommission Zürich 08.12.2016
2016-01907 INCB 54828-203: A Phase 2, Open-Label, Monotherapy, Multicenter Study to Evaluate the Efficacy and Safety of INCB054828 in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement clinical trial drugs phase 2 multicentric B PD Dr. Balabanov Stefan Incyte Corporation University Hospital Zurich, 8091 Zurich
INSELSPITAL, University Hospital Bern, 3010 Bern
Kantonale Ethikkommission Zürich Kantonale Ethikkommission Bern 19.06.2017
2016-01906 A Prospective, Multi-Center, Randomized, Concurrently-Controlled Clinical Study of the BARD COVERA Arteriovenous (AV) Stent Graft in the Treatment of Stenosis in the Venous Outflow of AV Fistula Acces More ... clinical trial medical devices monocentric C3 Prof. Dr. med. Thomas Pfammatter BD / Bard Peripheral Vascular, Inc. UniversitätsSpital, Zürich
Kantonale Ethikkommission Zürich 09.02.2017 Study has ended
2016-01905 Retrospektive Studie über Häufigkeit von maligne Hyperthermie-verursachenden Ryanodin-Rezeptor Typ 1 Mutationen in der Schweiz und deren mögliche metabolische Wirkung auf den Body Mass Index der betro More ... personal data/biological material monocentric PD Dr. Oliver Bandschapp University Hospital Basel Department Anästhesie, Universitätsspital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 12.12.2016
2016-01904 A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent clinical trial drugs phase 3 monocentric C Dr. Nicolas Bonadies Onconova Therapeutics, Inc. Inselspital, Universitätsklinikum, Bern
Kantonale Ethikkommission Bern 15.06.2017 Study has ended
2016-01903 Kinematische und elektromyographische Analysen eines dynamischen Sitzsystems bei gesunden Erwachsenen non clinical, involving persons monocentric A Lars Donath Department of Sport, Exercise and Health University of Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 15.12.2016
2016-01902 Comparison of iterative reconstruction algorithms to optimize image quality of cerebral computed tomography angiography in patients with intracranial aneurysms personal data/biological material monocentric Dr.med. Vincent Dunet CHUV CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 20.12.2016
2016-01901 Serum neurofilament light chain levels: a biomarker for prediction of neurological disability in multiple sclerosis personal data/biological material monocentric Chiara Zecca Ospedale Regionale di Lugano Ospedale Regionale di Lugano, Lugano
Comitato etico cantonale Ticino 16.12.2016
2016-01900 SAKK 19/16
Binimetinib, pemetrexed and cisplatin, followed by maintenance with binimetinib and pemetrexed, in patients with advanced non-small cell lung cancer with KRAS mutations. A multicenter phas More ...
clinical trial drugs phase 1 multicentric C PD Dr. med. Martin Früh SAKK Kantonsspital St. Gallen, St. Gallen
Universitätsspital Basel, Basel
IOSI Ospedale Regionale di Bellinzona e Valli, Bellinzona
Kantonsspital Graubünden, Chur
Ethikkommission Ostschweiz (EKOS) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino 28.02.2017 Study has ended
2016-01899 Vergleich des klinischen Verlaufs von Infektionen mit unterschiedlichen Klebsiella Arten von 2014 - 2016 MASTERTHESE personal data/biological material monocentric PD Dr. med. Dr. phil. Adrian Egli, FAMH Clinical Microbiology Clinical Microbiology University Hospital, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 02.12.2016
2016-01898 Retrospektive Datenanalyse von häuslicher Gewalt von 2006 bis 2016 im universitären Notfallzentrum des Inselspitals Bern personal data/biological material monocentric Aristomenis Exadaktylos UNZ, Inselspital UNZ, Inselspital, Bern
Kantonale Ethikkommission Bern 18.01.2017
2016-01897 Primary graft dysfunction in lung transplantation personal data/biological material monocentric Prof. Dr. med. Ilhan Inci Thoraxchirurgie Universitätsspital Zürich Thoraxchirurgie Universität Zürich, Zürich
Kantonale Ethikkommission Zürich 08.02.2017
2016-01895 CLCZ696G2301- A multi-center, randomized, double-blind, active-controlled, parallel-group Phase 3 study to evaluate the efficacy and safety of LCZ696
compared to ramipril on morbidity and mortality i More ...
clinical trial drugs phase 3 multicentric B PD Dr. med. Lukas Hunziker Munsch Novartis Pharma Schweiz AG Inselspital Bern, Bern
Luzerner Kantonsspital, Luzern
Kantonsspital St. Gallen, St. Gallen
Cardiocentro Ticino, Lugano
Kantonale Ethikkommission Bern Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Comitato etico cantonale Ticino 01.02.2017 Study has ended
2016-01894 CHIld-Parent Immunisation Survey – CHIPS non clinical, involving persons monocentric A Prof. Dr. med. Ulrich Heininger UKBB UKBB, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 28.11.2016 yes Study has ended
2016-01893 International, multicenter, prospective registry to collect data
of treatment patterns in patients with bilateral condylar fracture
(BCFx) of the mandible
non clinical, involving persons multicentric A Dr. Florian Thieringer AO Foundation / AO ITC Universitätsspital Basel, Basel
Klinik für Mund-, Kiefer- und Gesichtschirurgie, UniversitätsSpital Zürich, Zürich
Ethikkommission Nordwest- und Zentralschweiz EKNZ Kantonale Ethikkommission Zürich 12.12.2016