BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2015-00044 M13-549: A Phase III, Randomized, Double-Blind Study Comparing ABT-494 to Placebo in Subjects with Moderately to Severely Active Rheumatoid Arthritis Who Are on a Stable Dose of Conventional Synthetic More ... clinical trial drugs phase 3 multicentric C Prof. Dr. Jean Dudler AbbVie AG HFR Kantonsspital Freiburg, Rheumatologie, 1708 Freiburg
Kantonsspital Aarau, Abteilung Rheumatologie, Aarau
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Ethikkommission Nordwest- und Zentralschweiz EKNZ 23.02.2016
2015-00043 M13-545: A Phase 3, Randomized, Double-Blind Study Comparing ABT-494 Once Daily Monotherapy to Methotrexate (MTX) Monotherapy in MTX-Naïve Subjects with Moderately to Severely Active Rheumatoid Arthri More ... clinical trial drugs phase 3 monocentric C Prof. Dr. Jean Dudler AbbVie AG Service de rhumatologie HFR Fribourg – Hôpital Cantonal, Fribourg
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 14.03.2016
2015-00042 SAKK 16/14
Anti-PD-L1 antibody MEDI4736 in addition to neoadjuvant chemotherapy in patients with stage IIIA(N2) non-small cell lung cancer (NSCLC). A multicenter single-arm phase II trial.
clinical trial drugs phase 2 multicentric C Dr. med. Sacha Rothschild SAKK Universitätsspital Basel, Basel
Inselspital Bern, Bern
Spital STS AG Thun, Thun
Kantonspital Aarau, Aarau
Kantonsspital Baden, Baden
Luzerner Kantonsspital, Luzern
St. Claraspital, Basel
Hôpitaux Univ More ...
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... 30.03.2016
2015-00041 Factors predicting the forgotten joint score after total knee arthroplasty. personal data/biological material monocentric MD Henrik Behrend Dep of Orthopaedic Surgery, KSSG KSSG, St. Gallen
Ethikkommission Ostschweiz (EKOS) 07.12.2015
2015-00040 A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled,
Multicenter Study Evaluating the Safety and Efficacy of Obeticholic Acid in
Subjects with Nonalcoholic Steatohepatitis
clinical trial drugs phase 3 multicentric C Prof. Dr. Annalisa Berzigotti Intercept Pharma Switzerland GmbH University Clinic of Visceral Surgery and Medicine, Bern
Kantonsspital St. Gallen, St. Gallen
EPATOCENTRO TICINO, Lugano
USZ, University of Zurich, Zürich
Kantonale Ethikkommission Bern Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich, Comitato etico cantonale Ticino 01.06.2016
2015-00039 BIOTRONIK – Safety and clinical performance of the self-expanding transcatheter BIOVALVE prosthesis in subjects with severe symptomatic calcified aortic valve stenosis suitable for transfemoral transc More ... clinical trial medical devices monocentric C2 Prof. Robert Bauernschmitt BIOTRONIK AG - Clinical Affairs UniversitätsSpital Zürich - Klinik für Herz- und Gefässchirurgie, Zürich
Kantonale Ethikkommission Zürich 08.03.2016
2015-00038 Auswirkungen der Implementierung eines Gerinnungsmanagement-
Algorithmus bei herzchirurgischen Patienten – Eine Qualitätskontrolle

Impact of a coagulation management algorithm in cardiac surgery - More ...
personal data/biological material monocentric Prof. Dr. Christoph Hofer Institut für Anästhesiologie und Intensivmedizin Stadtspital Triemli Institut für Anästhesiologie und Intensivmedizin Stadtspital Triemli, Zurich
Kantonale Ethikkommission Zürich 22.12.2015
2015-00037 Predictive biomarkers of individual trajectories in elderly persons with subtle cognitive decline non clinical, involving persons monocentric A Professor Panteleimon Giannakopoulos Hôpitaux Universitaires de Genève Hôpitaux Universitaires de Genève, Genève
Commission Cantonale d'éthique de la recherche Genève (CCER) 08.12.2016
2015-00035 DEVELOPMENT OF A SYSTEM TO ASSESS LOCOMOTION OF FRAIL OLDER ADULTS IN TWO DIFFERENT ENVIRONMENTS non clinical, involving persons monocentric A Dr. Amandine Dubois University of Fribourg University of Fribourg, Fribourg
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 02.02.2016 Study has ended
2015-00034 Prevalence of HPV infection using self-sampling screening and monitoring the Earlier Impact of HPV-Vaccination Program in Switzerland clinical trial medical devices monocentric A Prof Patrick Petignat Geneva university hospital Hopital universitaire de Geneve, geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 05.01.2016 Study has ended
2015-00033 A Phase I/II, multicenter, open-label, dose-escalation study of the safety and pharmacokinetics of cobimetinib in pediatric and young adult patients with previously treated solid tumors clinical trial drugs phase 1 monocentric C Dr. Nicolas Gerber F. Hoffmann-La Roche Ltd. Universitäts-Kinderspital, Zürich
Kantonale Ethikkommission Zürich 15.07.2016 yes Study has ended
2015-00032 The effect of biopolymer based lipid emulsions on GI function, GI peptide response
and satiation in healthy volunteers; a randomized, double blind, unbalanced threeway crossover study.
clinical trial other clinical trials monocentric B Dr. Andreas Setingoetter University Hospital Zurich University Hospital Zurich, Zurich
Kantonale Ethikkommission Zürich 01.04.2016 Study has ended
2015-00031 Double-blind, randomized, placebo-controlled, phase III study on the efficacy and tolerability of a 48-week treatment with two different doses of budesonide effervescent tablets vs. placebo for mainte More ... clinical trial drugs phase 3 multicentric C Dr. med. Alain Schoepfer Dr. Falk Pharma GmbH University Hospital Lausanne/CHUV Division of Gastroenterology and Hepatology, Lausanne
Praxis für Gastroenterologie, Römerstraße 7, CH-4600 Olten
Universitätsklinik Basel Abteilung für Gastroenterolo More ...
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich 25.05.2016 Study has ended
2015-00030 Etude sur le vécu de l'instauration du mode d'alimentation du nouveau-né à la maternité chez les mères ayant accouché au CHUV en fonction de leurs critères de choix et de leurs connaissances prénatale More ... non clinical, involving persons monocentric A Ms Avignon Valérie Centre hospitalier Universitaire Vaudois CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 06.01.2016
2015-00029 Impact of 2014-2015 influenza season on the activity and workload of an emergency service personal data/biological material monocentric Professeur Bertrand Yersin Service des Urgences du CHUV CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 25.01.2016
2015-00027 Myo-inositol and chiro-inositol quantification in plasma and urine : method development and potential interaction with pregnancy state non clinical, involving persons monocentric A Dr Maurice Beaumont Nestlé Research Center Nestlé Research Center, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 18.11.2015 Study has ended
2015-00026 Implementation of the Flow Mediated Dilation Method at NRC/Metabolic Unit: training of operators on healthy volunteers non clinical, involving persons monocentric A Maurice Beaumont, MD, PhD Nestlé Research Center Nestlé Research Center, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 06.01.2016
2015-00024 Effects of empagliflozin an SGLT2-inhibitor on healthy volunteers with induced hypotonic hyponatremia - the DIVE-study clinical trial drugs n/a monocentric C Prof / Mirjam / Christ Endokrinologie, Universitätsspital Basel Endocrinology , Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 08.01.2016 Study has ended
2015-00023 GS-US-326-1100: A Combined Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Induction and Maintenance Study Evaluating the Safety and Efficacy of GS-5745 in Subjects with Moderately to Severel More ... clinical trial drugs phase 2 multicentric C Prof. Dr Gerhard Rogler Gilead Sciences USZ, Zürich
Gastroenterologische Praxis Balsiger, Seibold & Partner, Bern
USB Gastroenterologie und Hepathologie , Basel
Kantonale Ethikkommission Zürich Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern 18.03.2016 Study has ended
2015-00022 Pediatric pain management after tonsillectomy as a model to assess the feasibility of clinical studies in children in an at-home setting

Pädiatrisches Schmerzmanagement nach Tonsillektomie als Mod More ...
non clinical, involving persons monocentric A Prof. Dr. med. Christiane Pauli-Magnus Clinical Trial Unit, Department of Clinical Research, University Hospital Basel University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 03.01.2016 yes Study has ended