| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-00752 | Observational study for assessing treatment and outcome of patients with primary brain tumours diagnosed according to cIMPACT-NOW recommendations and the 2021 WHO classification | non clinical, involving persons | multicentric | A | Dr Hans-Georg Wirsching | European Organisation for Research and Treatment of Cancer (EORTC) |
UniversitaetsSpital Zurich - Neurology Clinic, Zurich Centre Hospitalier Universitaire Vaudois - Lausanne, Lausanne |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 12.01.2024 | |||||
| 2023-00751 | Plasma copeptin in response to oral urea in healthy adults and patients with polyuria-polydipsia syndrome: a double-blind, randomized, placebo-controlled cross-over proof-of-concept and pilot study | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Mirjam Christ-Crain | Universitätsspital Basel |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.05.2023 | |||||
| 2023-00750 | TRI0358 - Investigation of CD40 Blockade in Salivary Gland Biopsies from Sjögren’s Syndrome Patients | personal data/biological material | monocentric | Dr. Grazyna Wieczorek | Novartis Pharma AG - NIBR |
Novartis Pharma AG, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.04.2023 | |||||||
| 2023-00749 | Prevalence of PD-L1 expression in gastric and GEJ cancer patients in Switzerland | personal data/biological material | multicentric | Dr. Alexander Siebenhüner | MSD Merck Sharp & Dohme AG, |
Hirslanden Zürich AG, Zürich Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 24.11.2023 | ||||||
| 2023-00748 | Modeling and Workflow Recognition for the Anterior Approach in Total Hip Arthroplasty | non clinical, involving persons | multicentric | A | Prof. Philipp Fürnstahl | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich Kantonsspital Baden, Baden Kantonsspital Winterthur, Winterthur |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 20.06.2023 | |||||
| 2023-00747 | Retrospective analysis of diagnosis, treatment, associated injuries and clinical and radiological outcome of traumatic occipital condyle fractures | personal data/biological material | monocentric | Dr. med. Christopher Marvin Jesse | Universitätsklinik für Neurochirurgie |
Universitätsklinik für Neurochirurgie, Bern |
Kantonale Ethikkommission Bern | 25.07.2023 | |||||||
| 2023-00746 | MK-0472-001: A Phase 1/1b Open-label, Multicenter Clinical Study of MK-0472 as Monotherapy and Combination Therapy in Participants with Advanced/Metastatic Solid Tumors. | clinical trial | drugs | phase 1 | multicentric | C | Dr. med. Ilaria Colombo | Merck Sharp & Dohme LLC |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona Hôpitaux Universitaires de Genève, Genève Kantonsspital St. Gallen, St. Gallen |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS), Commission Cantonale d'éthique de la recherche Genève (CCER) | 22.06.2023 | |||
| 2023-00745 | 5 years of Birthing Centre at a Perinatal Centre | personal data/biological material | monocentric | Pract. med. Julia Popelka | Kantonsspital Aarau |
Kantonsspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.05.2023 | |||||||
| 2023-00744 |
1.Occurence of Long-Covid in patients after inpatient rahabilitation due to acute Covid-19 infection. 2.How easy it is for patients to retur to everyday life and work after inpatient rehabilitation More ... |
non clinical, involving persons | monocentric | A | Prof. Dr. Stefan Bachmann |
Kliniken Valens, Valens |
Ethikkommission Ostschweiz (EKOS) | 16.11.2023 | |||||||
| 2023-00743 | Effects of microbiological and immunological factors on the lower urinary tract | non clinical, involving persons | monocentric | A | Prof. Dr. Thomas Kessler | Universität Zürich |
Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 07.07.2023 | ||||||
| 2023-00742 | Prevalence, evolution, determinants, and outcomes of self-reported physical activity among solid organ transplant recipients: Analysis of the prospective Swiss Transplant Cohort Study | personal data/biological material | monocentric | Prof. Sabina De Geest | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.07.2023 | |||||||
| 2023-00741 | A Phase 3, Two-stage, Randomized, Multi-center, Controlled, Open-label Study Comparing Iberdomide Maintenance to Lenalidomide Maintenance Therapy after Autologous Stem Cell Transplantation (ASCT) in P More ... | clinical trial | drugs | phase 3 | monocentric | C | PD Dr. Sabine Veronika Gerull | Celgene Corporation |
KSA - Kantonspital Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 23.06.2023 | ||||
| 2023-00740 | Evaluation of preoperative 3D reconstruction software Visible PatientTM on postoperative outcome in terms of reduction of complications after minimally invasive anatomical lung resection compared to s More ... | personal data/biological material | monocentric | Dr. Aljaz Hojski | Universitätsspital Basel |
University Hospital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.04.2023 | Study has ended | ||||||
| 2023-00739 | Autonome Regulation (aR) bei obstruktivem Schlafapnoe-Syndrom (OSAS) mit und ohne Diabetes mell. Typ 2 (T2D) und einer gesunden Kontrollgruppe. | non clinical, involving persons | monocentric | A | PD Dr. med Matthias Kröz | Forschungsinstitut Havelhöhe gGmbH |
Klinik Arlesheim, Arlesheim |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 29.06.2023 | ||||||
| 2023-00737 | A phase 1/2 trial of EO2401, a novel microbial-derived peptide therapeutic vaccine, in combination with PD-1 check point blockade, for treatment of patients with locally advanced or metastatic adrenoc More ... | clinical trial | drugs | phase 2 | monocentric | C | Prof. Dr. med Svenja Nölting | Enterome |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 24.11.2023 | Study has ended | |||
| 2023-00736 | Brain connectivity between networks implied in inhibition and cue-reactivity in alcohol use disorder | non clinical, involving persons | multicentric | A | PD Dr. Matthias Grieder | University Hospital for Psychiatry and Psychotherapy Bern |
University Hospital for Psychiatry and Psychotherapy, Bern Klinik Südhang, Kirchlindach |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Bern | 19.06.2023 | |||||
| 2023-00734 | Présentation clinique, prise en charge et évolution à long terme des patients adultes atteints de thrombocytopénie immune au CHUV : une analyse rétrospective sur 10 ans | personal data/biological material | monocentric | Prof. Lorenzo Alberio | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 17.07.2023 | |||||||
| 2023-00733 |
The LYMPH Trial - Surgical versus Conservative Complex Physical Decongestion Therapy for Chronic Breast Cancer-Related Lymphedema: A Pragmatic, Randomized, Multicenter Superiority Trial |
clinical trial | other clinical trials | multicentric | A | PD Dr. med. Elisabeth Kappos | University Hospital Basel |
University Hospital Basel, Basel Kantonsspital Aarau AG, Aarau Hôpitaux universitaires de Genève, Genève Ospedale Regionale di Lugano, Lugano Centre hospitalier universitaire vaudois, Lausanne Kantons More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Commission Cantonale d'éthique de l More ... | 22.05.2023 | ||||
| 2023-00731 | Relationship between neurocognitive, sensory and motor function for hand dexterity | non clinical, involving persons | monocentric | A | Dr. med. Meret Branscheidt | cereneo |
cereneo, Weggis |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.06.2023 | ||||||
| 2023-00730 | A comparison of pharmacogenomic raw genotyping data from DTC-GT services and third-party interpretation websites with conventional laboratory testing | non clinical, involving persons | monocentric | A | Dr. med. Jérôme Bonzon |
USZ, Zürich |
Kantonale Ethikkommission Zürich | 11.07.2023 | |||||||