| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-02508 | Resection of the primary tumor vs. systemic treatment alone for patients with small intestinal neuroendocrine tumors and unresectable metastases: a retrospective, Europe-wide, pooled cohort study (Sur More ... | personal data/biological material | multicentric | Prof. Dr. med. Reto Kaderli | Inselspital |
Universitätsklinik für Viszerale Chirurgie und Medizin, Insespital Bern, Bern University Hospital of Basel, Basel Centre hospitalier universitaire vaudois (CHUV), Lausanne |
Kantonale Ethikkommission Bern | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 04.02.2025 | ||||||
| 2024-02507 | Adhésion thérapeutique des enfants et des adolescent·es suivi·es à la consultation d’adhésion de la Pharmacie d’Unisanté [Therapeutic adherence of children and adolescents followed at the Unisanté Pha More ... | personal data/biological material | monocentric | PD MER Jérôme Berger | Unisanté |
Unisanté, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.01.2025 | Study has ended | ||||||
| 2024-02506 | AI assisted diagnosis of endometriosis based on transvaginal ultrasound | personal data/biological material | monocentric | Dr. med. Mark Ormos | Scanvio Medical AG |
Kantonsspital Baden AG, Baden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.01.2025 | Study has ended | ||||||
| 2024-02505 | Exploring Patient Attitudes Towards Intravitreal Injections for Geographic Atrophy in dry AMD: A Survey Study | non clinical, involving persons | multicentric | A | Dr. med. Gábor Márk Somfai | Stadtspital Zürich |
Stadtspital Zürich, Zürich Gutblick, Wetzikon |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Zürich | 11.07.2025 | |||||
| 2024-02504 | Natural history of cardiac transthyretin amyloidosis - mechanistic insights by multimodality imaging | non clinical, involving persons | monocentric | B | Dominik Benz | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 01.07.2025 | ||||||
| 2024-02503 | Development of a portable medical genetics laboratory: Initial testing with volunteers from Western Switzerland with HbS or HbC alleles | non clinical, involving persons | monocentric | A | Dr Cécile CHOUDJA OUABO-JEROME | Uni Bern |
INDEPENDANT, LAUSANNE |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.03.2025 | ||||||
| 2024-02502 |
EORTC-LEGATO Lomustine with or without reirradiation for first progression of glioblastoma: a randomized phase III study |
clinical trial | drugs | phase 3 | multicentric | B | PD Dr. med. Emilie le Rhun | EORTC |
Universitätsspital Zürich, Zürich Istituto Oncologico della Svizzera Italian, Bellinzona |
Kantonale Ethikkommission Zürich | Comitato etico cantonale Ticino | 08.04.2025 | |||
| 2024-02501 | Cold snare unroofing of subepithelial lesions in the GI tract | personal data/biological material | monocentric | Dr. med. Bernhard Morell | Abteilung für Gastroenterologie |
Abteilung für Gastroenterologie, Stadtspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 04.04.2025 | Study has ended | ||||||
| 2024-02500 | Epidemiology and outcomes of acyclovir/foscarnet-refractory/resistant mucocutaneous HSV infections in allogeneic hematopoietic cell transplant recipients | personal data/biological material | multicentric | Dionysios Neofytos | HUG |
Hôpitaux Universitaires de Genève, Geneva University of Basel, Basel Universitätsspital Zürich, Zürich |
Commission Cantonale d'éthique de la recherche Genève (CCER) | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich | 24.01.2025 | ||||||
| 2024-02499 | Phase I/Ib, Open-label, Dose-escalating, Clinical and Pharmacokinetic Study of PM54 Administered Intravenously to Patients with Selected Advanced Solid Tumors | clinical trial | drugs | phase 1 | multicentric | C | Dr. Ioannis Metaxas | Pharma Mar, S.A. |
Spital Thurgau AG, including Kantonsspital Münsterlingen and Frauenfeld, Münsterlingen and Frauenfeld Ente Ospedaliero Cantonale ( EOC ); Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona |
Ethikkommission Ostschweiz (EKOS) | Comitato etico cantonale Ticino | 19.06.2025 | |||
| 2024-02496 | 20230005_A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig vs Cabazitaxel or Second Androgen Receptor-Directed Therapy in Subjects With Metastatic Castration-Resistant Prostate Cance More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr . Richard Cathomas | Amgen Inc |
Departement Innere Medizin, Onkologie und Haematologie, Kantonsspital Graubuenden, Chur Medizinische Onkologie, Inselspital Bern, Bern Klinik für Onkologie Hämatologie, HOCH Health Ostschweiz, Kantons More ... |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Comitato etico cantonale Ticino | 29.04.2025 | |||
| 2024-02495 | CESARCOM. Improving therapeutic communication during c-section to decrease patients’ anxiety and enhance professionals’ satisfaction. | non clinical, involving persons | monocentric | A | Dr Océane Pécheux | HUG |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 06.05.2025 | ||||||
| 2024-02494 | Femoral cortical thickness index - Accuracy of computed-tomography measurements and correlation with Hounsfield units and dual-energy X-ray absorptiometry | personal data/biological material | monocentric | MD Method Kabelitz | Stadtspital Zürich |
Stadtspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 16.05.2025 | |||||||
| 2024-02493 | Evaluation of endogenous biomarkers for phenotyping of drug metabolising enzymes and transporters in patient serum samples | personal data/biological material | monocentric | Prof. Dr. Samuel Allemann | University of Basel |
University of Basel, Department Pharmaceutical Sciences, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.01.2025 | |||||||
| 2024-02491 | VOLTRAC - Impact de la surcharge VOLémique précoce sur les complications post-opératoires après TRAnsplantation Cardiaque | personal data/biological material | monocentric | Pr Lucas Liaudet | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 06.02.2025 | |||||||
| 2024-02490 | Bridging Centers, Enhancing Knowledge: A Research Protocol on Federated Learning for Dental Implant Classification and Pathology Identification in Periapical Radiographs | personal data/biological material | monocentric | Prof. Dr. Dr. h.c., Mutlu Özcan, PhD | Universität Zürich |
Klinik für Kaufunktionsstörungen und dentale Materialwissenschaften, Zentrum für Zahnmedizin, Universität Zürich, Zürich |
Kantonale Ethikkommission Zürich | 25.03.2025 | |||||||
| 2024-02489 | Concordance entre pulse oxymètres lors d’un test de marche standardisé de 6 minutes | non clinical, involving persons | monocentric | A | Professor Jean-Paul Janssens | Hôpital de La Tour |
Hôpital de La Tour, 1217 Meyrin, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 18.03.2025 | ||||||
| 2024-02488 | Factors contributing to unique breath profiles generated by electronic Nose in children with chronic respiratory disorders | non clinical, involving persons | monocentric | A | PD Dr med Elias Seidl | University Children’s Hospital Zürich |
University Children’s Hospital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 06.06.2025 | yes | |||||
| 2024-02486 |
Complications after surgical stabilization of rib fracture (SSRF) - single-center experience |
personal data/biological material | monocentric | Dr. med. Maria Barbara Svec | Department of Thoracic Surgery, University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.01.2025 | Study has ended | ||||||
| 2024-02485 | Vestibular Function Before and After Cochlear Implantation: A Single-Center Cohort Study Experience | personal data/biological material | monocentric | PD Dr Nils Guinand | Hôpitaux universitaires de Genève |
Service d'oto-rhino-laryngologie et de chirurgie cervico-faciale, Hôpitaux universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 25.02.2025 | |||||||