| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01963 | Companion Diagnostics: Performance of VENTANA HER2/neu (4B5) IUO Assay with ultraView Detection on the BenchMark ULTRA® Instrument as a Diagnostic Device for Determining HER2-Low Status in DUALITYBIO More ... | personal data/biological material | monocentric | Dr. Claire Bégot | Ventana Medical Systems, Inc |
Labcorp CLS, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.11.2023 | |||||||
| 2023-01952 | Integrated molecular and clinical profiling to improve disease characterization and outcome prediction in nodal marginal zone lymphoma | personal data/biological material | multicentric | Dr. med. Maria Cristina Pirosa | International Extranodal Lymphoma Study Group (IELSG) |
Oncology Institute of Southern Switzerland and Institute of Oncology Research, Bellinzona University Hospital Basel, Basel Hôpitaux Universitaires Genevois (HUG), Genève Universitätsspital Zürich (USZ More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Zürich, Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.11.2023 | ||||||
| 2023-01947 | Entwicklung eines Machine-Learning Programms für ein Monitoring von Kinder- und Jugendunfällen | personal data/biological material | monocentric | Julia Dratva | ZHAW |
ZHAW, Winterthur |
Kantonale Ethikkommission Zürich | 28.11.2023 | |||||||
| 2023-01944 | Long-term clinical outcome of pediatric, adolescent and young adult patients with chordoma or chondrosarcoma treated with pencil beam scanning proton therapy | personal data/biological material | monocentric | Dr.Miriam Vazquez | Center for Proton Therapy at Paul Scherrer Institut |
Center for Proton Therapy at Paul Scherrer Institut, Villigen |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.11.2023 | |||||||
| 2023-01943 | Magnetic Resonance evaluation of the pudendal nerves in patients with endometriosis and chronic pelvic pain | non clinical, involving persons | monocentric | A | Prof dr.ssa med Stefania Rizzo | Ente Ospedaliero Cantonale |
Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 27.11.2023 | ||||||
| 2023-01939 | Helicobacter pylori seropositivity as possible predictor of lack of response to immunotherapy in patients with hepatocellular carcinoma. | personal data/biological material | monocentric | Prof. Annalisa Berzigotti | Insel Gruppe AG |
Insel Gruppe AG, Bern |
Kantonale Ethikkommission Bern | 13.11.2023 | |||||||
| 2023-01937 | Comparative bioavailability study of a new IBSA Lorazepam 2.5 mg orodispersible film and Tavor® (lorazepam) 2.5 mg film-coated tablets in healthy volunteers under fasting conditions | clinical trial | drugs | phase 1 | monocentric | C | Dr. Milko Radicioni | IBSA Institut Biochimique S.A. |
CROSS Research S.A. Phase I Unit, CH-6864 Arzo, Switzerland |
Comitato etico cantonale Ticino | 08.11.2023 | ||||
| 2023-01935 | MS Balance: Comparison of the lab-based measurement of static and dynamic balance ability and corresponding clinical assessments in patients with multiple sclerosis - a pilot study | clinical trial | other clinical trials | monocentric | A | Frank Behrendt | Reha Rheinfelden |
Reha Rheinfelden, Rheinfelden |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.11.2023 | |||||
| 2023-01934 | Mucosal and systemic immunity after infection with common-cold respiratory viruses | personal data/biological material | monocentric | Prof. Isabella Eckerle | University Hospital of Geneva |
University Hospitals of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 30.10.2023 | |||||||
| 2023-01929 | Measures of smouldering MS in natalizumab and ocrelizumab treated MS patients | non clinical, involving persons | monocentric | A | Prof Chiara Zecca | Neurocenter of Southern Switzerland, Ente Ospedaliero Cantonale |
Neurocenter of Southern Switzerland, Lugano |
Comitato etico cantonale Ticino | 08.11.2023 | ||||||
| 2023-01920 | Precision diagnosis and prognosis of progressive fibrosing interstitial lung diseases using an artificial intelligence-based multi-omics approach | personal data/biological material | monocentric | Prof. Dr. med. Britta Maurer | Klinik für Rheumatologie und Immunologie |
Inselspital, Bern |
Kantonale Ethikkommission Bern | 31.10.2023 | |||||||
| 2023-01919 | Expérience des souvenirs traumatiques intrusifs et besoins suite à des événements traumatogènes répétés chez les infirmier·ère·s et les sages-femmes : étude qualitative (STADE) | non clinical, involving persons | monocentric | A | Prof Antje HORSCH | CHUV |
CHUV & UNIL, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 28.11.2023 | ||||||
| 2023-01916 | EXPECT – Patient expectations and their fulfilment in patients with total knee arthroplasty | non clinical, involving persons | multicentric | A | Prof. Dr. med. Markus Arnold | Praxis MEIN KNIE |
Praxis MEIN KNIE, Münchenstein Praxis LEONARDO, Münchenstein |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.11.2023 | |||||
| 2023-01907 | Companion Diagnostic: Diagnostic Protocol for Use of Ventana PD-L1 (SP263) CDx Assay in AstraZeneca Study D7988C00001 (eVOLVE-Meso) | personal data/biological material | monocentric | Dr Claire Begot | Ventana Medical Systems, Inc |
Labcorp CLS, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 21.11.2023 | |||||||
| 2023-01904 |
SINGLE-ISOCENTER SBRT VS MULTIPLE-ISOCENTER SBRT FOR MULTIPLE EXTRACRANIAL METASTASES: a randomized controlled non-inferiority clinical trial |
clinical trial | other clinical trials | monocentric | A | Professor Matthias Guckenberger | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 21.11.2023 | |||||
| 2023-01901 | Evolution of need for Electrophysiologic testing and radiofrequency ablation in adults with congenital heart disease 1996-2023 | personal data/biological material | monocentric | Prof. Matthias Greutmann | University Hospital Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 17.11.2023 | |||||||
| 2023-01900 | “Treatment intensification for advanced cervical cancer: Tolerability and feasibility of concurrent gemcitabine and cisplatin combined with modern radiotherapy” | personal data/biological material | monocentric | Dr. med. Elena Riggenbach | Universitätsspital Bern |
Universitätsspital Bern, Department of Radiation Oncology, 3010 Bern |
Kantonale Ethikkommission Bern | 15.11.2023 | |||||||
| 2023-01891 | GLEAM: Noninvasive GLucose Measurement using ImpEdAnce ToMography – a pilot project | non clinical, involving persons | monocentric | A | Prof. Christoph Stettler | Department of Diabetes, Endocrinology, Nutritional Medicine and Clinical Nutrition (UDEM) |
UDEM Inselspital, Bern |
Kantonale Ethikkommission Bern | 22.11.2023 | ||||||
| 2023-01883 | Inzidenz und Auswirkung von postoperativen Frührezidiven bei Glioblastomen | personal data/biological material | monocentric | Dr. med. Levin Häni | Universitätsklinik für Neurochirurgie |
Universitätsklinik für Neurochirurgie, Bern |
Kantonale Ethikkommission Bern | 14.11.2023 | |||||||
| 2023-01882 | The influence of highly aspherical lenslets on subfoveaal choroidal thickness and axial length | non clinical, involving persons | monocentric | A | Dr. Martin Lörtscher | Fachhochschule Nordwestschweiz |
Fachhochschule Nordwestschweiz, Institut für Optometrie, Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 08.11.2023 | ||||||