| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-D0013 | A Randomized, Double-Blind, Phase 3 Study of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer | clinical trial | in vitro diagnostic medical devices CDx | multicentric | C1 | Dr. Anna Dorothea Wagner | Incyte Corporation |
CHUV, Lausanne University Hospital, Lausanne Inselspital- Universitaetsspital Bern, Bern HOCH Health Ostschweiz, Kantonsspital St. Gallen Rorschacher Strasse 95 |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS) | 06.05.2026 | ||||
| 2026-D0012 | Safety and performances of the LINEA cardiac pacing lead optimized for the implantation in interventricular septum | clinical trial | medical devices | monocentric | C2 | Pr. Haran Burri | SORIN CRM SAS (MicroPort CRM) |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 18.05.2026 | |||||
| 2026-D0009 | Clinician- and patient-reported outcome measures (ClinROs/PROMs) following implant placement with open vs submerged healing of native collagen membranes (BioGide® Compressed) | clinical trial | medical devices | monocentric | A1 | Dr. med.dent. Marina Siegenthaler | Zahnarzt Praxis GRIMM Zahnärzte |
Zahnarzt Praxis GRIMM Zahnärzte, Horgen |
Kantonale Ethikkommission Zürich | 29.04.2026 | |||||
| 2026-D0008 | Basel Kosten-Effektivitäts-Trial: Drug-coated balloon vs. drug-eluting stent strategy in high-risk patients with coronary artery disease | clinical trial | medical devices | multicentric | A1 | Prof Gregor Leibundgut | B.BRAUN Melsungen AG - Vascular Systems |
Universitätsspital Basel, Basel Stadtspital Zürich Triemli, Birmensdorferstrasse 497 |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Zürich | 20.05.2026 | ||||
| 2026-D0007 | The Fourth Left Atrial Appendage Occlusion Study: (LAAOS-4) | clinical trial | medical devices | monocentric | A2 | Prof. Dr. med. Christian Sticherling | Hamilton Health Sciences Corporation through its Population Health Research Institute (PHRI) |
Univeristätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.04.2026 | |||||
| 2026-D0006 | Exploration of the functional effect of modified gain precalculation on soft speech intelligibility | clinical trial | medical devices | monocentric | A1 | Josephine Hollenbach | Sonova AG |
Sonova AG, Stäfa |
Kantonale Ethikkommission Zürich | 17.04.2026 | Study has ended | ||||
| 2026-D0005 | Diagnostic Protocol for Evaluating the Clinical Performance of VENTANA FOLR1 (FOLR1-2.1) IUO Assay in Determining FOLR1 Status in Tumor Specimens from Platinum-Resistant Ovarian Cancer Patients in Ast More ... | clinical trial | in vitro diagnostic medical devices CDx | multicentric | C1 | Prof. Dr. Viola Heinzelmann-Schwarz | Ventana Medical Systems, Inc. (Roche Tissue Diagnostics [RTD]) |
Universitätsspital Basel, Basel Spital STS AG - Spital Thun - Onkologie- und Hamatologiezentrum, Thun Spital Thurgau-Kantonsspital Muensterlingen, Spitalcampus 1 Kantonsspital St. Gallen, Rorschacher More ... |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 27.05.2026 | ||||
| 2026-D0004 | Multicentric randomized single-blinded controlled clinical trial comparing additively and subtractively manufactured implant supported fixed dental prostheses | clinical trial | medical devices | monocentric | A1 | Dr. Kevser Pala | Harvard School of Dental Medicine |
University of Zurich, Clinic of Reconstructive Dentistry, Zurich |
Kantonale Ethikkommission Zürich | 19.06.2026 | |||||
| 2026-D0001 | Effect of transcranial random noise stimulation on the performance in language tasks | clinical trial | medical devices | monocentric | A1 | Prof. Adrian Guggisberg | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.03.2026 | |||||
| 2026-01758 | Complications and reoperations after operative management of midshaft clavicle fractures: a retrospective study | personal data/biological material | monocentric | Nico Kleemann | Kantonsspital St. Gallen |
Kantonsspital St. Gallen, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 12.08.2026 | |||||||
| 2026-01741 |
Paving the Way for Tumor-Infiltrating Lymphocyte (TIL) Therapy in Childhood Cancer: A Feasibility Study at UKBB in Collaboration with USB |
personal data/biological material | monocentric | Dr. med. Renata Rosa Pereira | Universitäts-Kinderspital beider Basel |
Universtiäts-Kinderspital beider Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.08.2026 | |||||||
| 2026-01738 | Primary Total Wrist Arthroplasty for Complex Distal Radius Fractures in Patients Older Than 60 Years | personal data/biological material | monocentric | Dr. med Martina Greminger | HOCH Health Ostschweiz, Kantonsspital St Gallen |
HOCH St Gallen, St Gallen |
Ethikkommission Ostschweiz (EKOS) | 06.08.2026 | |||||||
| 2026-01731 | Patterns of care in stage I-III non-small cell lung cancer in Switzerland | personal data/biological material | monocentric | Prof. Dr. med. Markus Joerger | HOCH |
Dep. of Medical Oncology and Hematology, Cantonal Hospital, St.Gallen |
Ethikkommission Ostschweiz (EKOS) | 13.08.2026 | |||||||
| 2026-01656 | Impact of Menopause on Disease Progression and Disease-Modifying Therapy Tolerability in Multiple Sclerosis | personal data/biological material | monocentric | Dr. med. Lara Diem |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.07.2026 | ||||||||
| 2026-01623 |
Management and Outcomes of Intrauterine Tamponade for Postpartum Hemorrhage: A Retrospective Cohort Study |
personal data/biological material | monocentric | Dr. med. Benedict Krischer, MPH |
Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.07.2026 | ||||||||
| 2026-01611 | Geschlechtsspezifische Unterschiede in Symptomen und diagnostischen Abklärungen bei ambulanten Notfallpatient:innen mit einer tiefen Beinvenenthrombose | personal data/biological material | monocentric | PD Dr. Dr. Ksenija Slankamenac | Institut für Notfallmedizin, Universitätsspital Zürich |
Institut für Notfallmedizin des Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 31.07.2026 | |||||||
| 2026-01610 | Grafalon versus Thymoglobulin in Kidney Transplantation: A Retrospective Single-Center Cohort Study of Efficacy, Safety, and Graft Outcomes | personal data/biological material | monocentric | PD Dr. med Matthias Diebold |
Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.07.2026 | ||||||||
| 2026-01606 | Beyond Ventilation – Multifactorial Determinants of Moderate and Severe Bronchopulmonary Dysplasia in Extremely Preterm Infants | personal data/biological material | monocentric | Prof. Vincenzo Cannizzaro, MD, PhD | University Hospital Zurich |
University Hospital Zurich, Department of Neonatology, Zurich |
Kantonale Ethikkommission Zürich | 07.08.2026 | |||||||
| 2026-01596 | Multimodal Data Collection and Visualization of Ex Vivo Surgical Training | deceased persons | monocentric | Prof. Dr. Philipp Fürnstahl | Universtitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 04.08.2026 | |||||||
| 2026-01594 | Sustained effect of mulberry leaf extract on postprandial glucose | personal data/biological material | monocentric | Darimont Christian | La Société des Produits Nestlé |
Société des Produits Nestlé SA - Nestlé Reseach, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 13.08.2026 | |||||||