| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-02587 | CA266-0008: ROSETTARCC-208: A Phase 1/2 Open-label, Multi-center, Randomized Study of Pumitamig Alone or in Combination with Ipilimumab or Cabozantinib in Participants with Advanced Renal Cell Carci More ... | clinical trial | drugs | phase 1/2 | multicentric | C | Dr. med Tobias Peres | Bristol-Myers Squibb Services Unlimited Company |
HOCH Health Ostschweiz (Kantonsspital St. Gallen), St. Gallen Universitätsspital Zürich, Klinik für Medizinische Onkologie und Hämatologie, Zürich Kantonsspital Graubünden, Departement Innere Medizin, More ... |
Ethikkommission Ostschweiz (EKOS) | Kantonale Ethikkommission Zürich | 26.02.2026 | |||
| 2025-02586 | Appropriateness of medication prescribing in nursing homes: A pre-post study to evaluate the effectiveness of a clinical pharmacology team-led, digitally supported, inter-professional intervention | clinical trial | other clinical trials | monocentric | A | Dr. med. Francesca Bedussi, Pg.Cert. | Lugano Istituti Sociali (LIS) |
Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, Lugano |
Comitato etico cantonale Ticino | 23.02.2026 | |||||
| 2025-02585 | Fatigue and Brain (FAB): Effects of Cognitive and Physical Fatigue on Neuromuscular and Executive Function: A Bidirectional Investigation | non clinical, involving persons | monocentric | A | M.sc. Romina Ledergerber | Department of Sport, Exercise and Health |
Department of Sport, Exercise and Health, University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.01.2026 | ||||||
| 2025-02584 | A Phase 3 Open-label Randomized Study Assessing the Efficacy and Safety of RLY-2608 + Fulvestrant Versus Capivasertib + Fulvestrant as Treatment for PIK3CA-mutant Hormone Receptor Positive, Human Epid More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. Anton Oseledchyk | Relay Therapeutics, Inc. |
Universitätsspital Basel, Basel Tumor Zentrum Aarau, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.02.2026 | |||
| 2025-02581 | Prospective randomized controlled trial of outpatient versus inpatient elective laparoscopic cholecystectomy | clinical trial | other clinical trials | multicentric | A | Prof. Dr. Pascal Probst | Spital Thurgau AG |
Spital Thurgau AG, Kantonsspital Frauenfeld, Chirurgische Klinik, Frauenfeld Spital Thurgau AG, Kantonsspital Münsterlingen, Chirurgische Klinik, Münsterlingen |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Ostschweiz (EKOS) | 05.03.2026 | ||||
| 2025-02579 |
EORTC DE-ESCALATE Intermittent Androgen deprivation Therapy in the era of AR pathway inhibitors; a phase 3 pragmatic randomized trial (DE-ESCALATE) |
clinical trial | drugs | phase 3 | multicentric | A | Dr. med. Fabio Turco | EORTC |
IOSI - Istituto Oncologico della Svizzera Italiana, Bellinzona STS AG, Thun Tumor Zentrum Aargau, Aarau St. Claraspital AG, Basel Luzerner Kantonsspital, Luzern Kantonsspital Olten, Olten HUG - Hôpita More ... |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich, Commission cantonale d'Éthique de la Recherche s More ... | 26.02.2026 | |||
| 2025-02578 | Exercise-Induced Pulmonary Edema (EIPE) and Cardiovascular Dynamics in Endurance Athletes: A Comparative Study of Young and Older Active Individuals | non clinical, involving persons | monocentric | A | KD Dr.med. Dovile Diktanaite | Universität Basel |
Departement für Sport, Bewegung und Gesundheit, Universität Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.03.2026 | ||||||
| 2025-02577 | Validation of the French version of the Medical Achievement Self-efficacy Scale (MASS) | non clinical, involving persons | monocentric | A | Dr. Valérie Carrard | University of Lausanne |
University of Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.02.2026 | ||||||
| 2025-02575 | Spatial biology of primary and metastatic colorectal cancer | personal data/biological material | monocentric | Prof. Dr. Dr. med. Andreas Moor |
ETH Zurich, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 27.01.2026 | ||||||||
| 2025-02574 | Course and outcome after surgical treatment in children and adolescents with pectus excavatum | personal data/biological material | monocentric | PD Dr. med. Dr. sc. nat. Raphael Vuille-dit-Bille | Universitäts-Kinderspital beider Basel |
Kinderchirurgie, Universitätskinderspital beider Basel (UKBB), Basel-Satdt |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.01.2026 | |||||||
| 2025-02571 | Role of antiphospholipid antibodies in patients with carotid artery stenosis undergoing endarterectomy | personal data/biological material | monocentric | Benjamin Wagner | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.01.2026 | |||||||
| 2025-02570 | Recherche Action Participative sur le Plan de Crise Conjoint et sa Digitalisation pour les adolescent.e.s | non clinical, involving persons | monocentric | A | Ms Pascale Ferrari | Institut et Haute Ecole |
CHUV, Service universitaire de psychiatrie de l'enfant et de l'adolescent, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.02.2026 | yes | |||||
| 2025-02562 | Perceived preparedness for clinical practice during the transition to medical residency | non clinical, involving persons | monocentric | A | Dr Valerie Carrard | Université de Lausanne |
Lausanne Medical School, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 02.03.2026 | ||||||
| 2025-02560 | Validation of the German Post-Intensive Care Syndrome Questionnaire among Adult ICU Survivors in Germany, Austria, and Switzerland | non clinical, involving persons | monocentric | A | Dr. Marie-Madlen Jeitziner | Universitätsklinik für Intensivmedizin |
Universitätsklinik für Intensivmedizin, Inselspital Bern, 3010 Bern |
Kantonale Ethikkommission Bern | 27.01.2026 | ||||||
| 2025-02559 | Influence of postoperative bed rest on the frequency of cerebrospinal fluid leaks after intradural surgeries in children | personal data/biological material | monocentric | Prof. Dr. med Jehuda Soleman | University Hospital Basel |
Universitätsspital Neurochirurgie Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 26.02.2026 | |||||||
| 2025-02556 | Association of temperature variability during therapeutic hypothermia on neurodevelopmental outcome in newborns with hypoxic ischemic encephalopathy | personal data/biological material | monocentric | Prof. Dr.med. Cornelia Hagmann | Children's University Hospital of Zurich |
Children's University Hospital of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 24.02.2026 | |||||||
| 2025-02553 | Satisfaction du déclenchement de l’accouchement par ballonnet à domicile : étude prospective | non clinical, involving persons | monocentric | A | Dre Hélène Legardeur | CHUV - DFME - Maternité |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 12.02.2026 | ||||||
| 2025-02552 | Retinal Evaluation of Post-Operative Anatomical Integrity and functional Response in Rhegmatogenous Retinal Detachment | non clinical, involving persons | monocentric | A | Priv.-Doz. Dr. Josep Callizo Planas | University Hospital Basel |
Eye Clinic of University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.02.2026 | ||||||
| 2025-02551 | Inflammatory pattern and skin barrier markers in eczema of the elderly and atopic dermatitis: similarities and differences | personal data/biological material | monocentric | Dr med et phil Susanne Radonjic |
Dermatologie Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 18.02.2026 | ||||||||
| 2025-02549 | Intrinsic neural timescales in rest and task states | non clinical, involving persons | monocentric | A | Prof Athina Tzovara | Universitätsklinik für Neurologie, Inselspital |
University of Bern, Bern |
Kantonale Ethikkommission Bern | 13.01.2026 | ||||||