| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-02160 | Behandlung der chronisch-rezidivierenden juvenilen Parotitis (CRJP) – Therapieerfolg der sialendoskopischen Cortisonspülung in einer retrospektiven Analyse | personal data/biological material | monocentric | Dr. Gunther Pabst | HNO Klinik Luzerner Kantonsspital |
Klinik für Hals-, Nasen-, Ohren- und Gesichtschirurgie Luzerner Kanatonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.11.2024 | |||||||
| 2024-02157 | Effect of Virtual Reality immersion on patient’s anxiety during high-flow nasal pre-oxygenation before general anaesthesia: a pilot study. | clinical trial | other clinical trials | monocentric | A | Dr Herve Schlotterbeck | Istituto CardioCentro Ticino, EOC |
Istituto CardioCentro Ticino - EOC, Lugano |
Comitato etico cantonale Ticino | 08.01.2025 | |||||
| 2024-02155 | Pharmaceutical treatment of cocaine use disorder – a qualitative interview study | non clinical, involving persons | monocentric | A | PD Dr. med. Marc Vogel, MScPH | UPK Basel |
Universitäre Psychiatrische Kliniken Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 18.12.2024 | ||||||
| 2024-02146 | Validation Study of the German parent proxy and child self-report health related quality of life measure for children with epilepsy (CHEQOL-25). | non clinical, involving persons | monocentric | A | Dr med Patricia Elsa Dill | UKBB |
UKBB, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 28.11.2024 | yes | |||||
| 2024-02145 | Comparison between nasopharynx and orobuccal/nasal swabs or saliva for detection of respiratory viruses (ORASAMP) | non clinical, involving persons | monocentric | A | Dr. med. Philipp Jent | Universitätsspital Bern, Inselspital |
University Hospital Bern, Inselspital, Bern |
Kantonale Ethikkommission Bern | 19.12.2024 | yes | |||||
| 2024-02144 | Impact of time interval between trauma and operation on clinical outcome in patients with delayed rib fixation | non clinical, involving persons | monocentric | A | Maria Svec | USB Department of Thoracic Surgery |
University Hospital, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 02.12.2024 | ||||||
| 2024-02142 | Early and Late Outcomes After Branched and Fenestrated Endovascular Aneurysm Repair: A Multicentre Analysis of Risk Factors and Stent-Graft Performance (MULTI-FEVAR) | personal data/biological material | monocentric | Prof. Dr. med. Vladimir Makaloski | Insel Gruppe AG |
Universitätsklinik für Gefässchirurgie, Inselspital, Universitätsspital Bern, Bern |
Kantonale Ethikkommission Bern | 07.01.2025 | |||||||
| 2024-02134 | MK-2140-010: A Randomized, Open-Label, Multicenter, Phase 3 Study of Zilovertamab Vedotin (MK-2140) in Combination With R-CHP versus R-CHOP in Participants With Previously Untreated Diffuse Large B-Ce More ... | clinical trial | drugs | phase 3 | multicentric | C | Prof. Dr. med. Anastasios Stathis | Merck Sharp & Dohme LLC |
Istituto Oncologico della Svizzera Italiana (IOSI), Bellinzona Kantonsspital Baden, Baden HOCH Health Ostschweiz – Kantonsspital St. Gallen, St. Gallen |
Comitato etico cantonale Ticino | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS) | 16.01.2025 | |||
| 2024-02132 |
Endovascular treatment of acute basilar artery occlusion: outcome comparison of ATTENTION / BAOCHE eligible versus ineligible patients. Analysis from the Swiss Stroke Registry |
personal data/biological material | monocentric | Dr. Joachim Fladt | Universitätsspital Bern |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 15.01.2025 | |||||||
| 2024-02130 | Major adverse cardiovascular events in cancer patients during and after treatment with immune checkpoint inhibitors | non clinical, involving persons | multicentric | A | Dr. Eveline Daetwyler | University Hospital Basel |
Cantonal Hospital St. Gallen, St. Gallen University Hospital Basel, Basel Cantonal Hospital Baden, Baden |
Ethikkommission Ostschweiz (EKOS) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 07.11.2024 | |||||
| 2024-02126 | Umsetzung von Empfehlungen zur medikamentösen Therapie nach Spitalentlassung (Masterarbeit Medizin) | personal data/biological material | monocentric | PD Dr. med. Patrick Beeler | Center for Clinical Research Universität Luzern |
Center for Clinical Research Universität Luzern, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 17.12.2024 | |||||||
| 2024-02124 | Decay of vaccine-specific antibodies among solid organ transplant patients | personal data/biological material | monocentric | Dr. Christiane Eberhardt | Centre de Vaccinologie, HUG |
HUG, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 10.12.2024 | |||||||
| 2024-02123 | Initial Management of upper airway obstruction in Pierre Robin Sequence | personal data/biological material | monocentric | PD Dr. Benito Benitez | Mund-Kiefer-Gesichtschirurgie |
Universitätsspital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 30.10.2024 | |||||||
| 2024-02122 | Gemeindeintegrierte Akutversorgung (GiA) im Kanton Luzern | personal data/biological material | monocentric | Dr. Ingeborg Warnke | Luzerner Psychiatrie AG |
Luzerner Psychiatrie AG, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.11.2024 | |||||||
| 2024-02118 | Randomized, controlled, multi-center phase II clinical trial for the treatment of patellofemoral osteoarthritis with nasal chondrocyte-based tissue engineered cartilage implantation vs current standar More ... | clinical trial | transplant products | multicentric | C | Gyözö Lehoczky | University Hospital Basel |
University Hospital Basel, Basel Crossklinik, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 12.12.2024 | ||||
| 2024-02116 |
Effects of intranasal Oxytocin on Sexual Well-Being in Patients with Arginine Vasopressin Deficiency (central Diabetes insipidus) and Healthy Controls - a double-blind randomized placebo-controlle More ... |
clinical trial | drugs | phase 2 | monocentric | B | Prof. Mirjam Christ-Crain | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.01.2025 | ||||
| 2024-02112 | Effects of elexacaftor-tezacaftor-ivacaftor on glucose tolerance in young people with cystic fibrosis – where do we stand after four years of therapy | personal data/biological material | monocentric | PD Dr. med Insa Korten | Inselspital, Bern University Hospital |
Inselspital, Bern University Hospital, Bern |
Kantonale Ethikkommission Bern | 05.11.2024 | |||||||
| 2024-02106 | The association between propofol-based anesthesia versus volatile-anesthetic anesthesia and recovery after ambulatory surgery: A international, multicenter retrospective cohort study | personal data/biological material | monocentric | Prof. Dr. med Martin Schläpfer | Beth Israel Deaconess Medical Center |
Institute of Anesthesiology, University Hospital Zurich, Zürich |
Kantonale Ethikkommission Zürich | 17.01.2025 | |||||||
| 2024-02102 | TRI0381 - Investigation of human immune responses to the Adeno-Associated Virus (AAV)-based gene therapy GT005 for the treatment of advanced age-related macular degeneration | personal data/biological material | monocentric | Maria Vono, PhD | Novartis Pharma AG - Biomedical Research |
Novartis Pharma AG - Biomedical Research, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 16.10.2024 | |||||||
| 2024-02101 | Molecular and functional analyses of baroreceptors in human aortic arch using material from deceased individuals | deceased persons | monocentric | Professor Alexander Zimmermann | UniversitätsSpital Zürich |
University Hospital Zurich (USZ), Zürich |
Kantonale Ethikkommission Zürich | 10.01.2025 | |||||||