| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-01281 | A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants with Idiopathic Pulmonary Fibrosis | clinical trial | drugs | phase 3 | multicentric | C | Katrin Esther Hostettler Haack | Bristol-Myers Squibb Services Unlimited Company |
Universitätsklinikum Basel, Basel Universitaetsspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 31.08.2023 | |||
| 2023-01280 | Investigating the temporal dynamics and connectivity patterns underlying conscious perception - an iEEG study with hospitalized patients suffering from epilepsy | non clinical, involving persons | monocentric | A | David Pascucci | Hôpitaux Universitaires de Genève & UNIGE |
HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 07.08.2023 | ||||||
| 2023-01278 | Computational fluid dynamics modeling (CFD) of wall shear stress (WSS) of internal carotid artery plaque to predict stroke | personal data/biological material | monocentric | PD Dr.med. David Bervini | Universitätsklinik für Neurochirurgie |
Universitätsklinik für Neurochirurgie, Bern |
Kantonale Ethikkommission Bern | 06.09.2023 | |||||||
| 2023-01277 |
Companion Diagnostic – Measurement of the SRP-9001-104 Phase Ib trial samples with Elecsys® Anti-AAVrh74 antibody immunoassay Trial ID: RD006647 |
personal data/biological material | monocentric | Ms Geraldine Peeters | Roche Diagnostics Solutions |
Labcorp, Meyrin |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 24.07.2023 | |||||||
| 2023-01276 | Effects of Physical exercise timing On strength and Cardiometabolic Health. | clinical trial | other clinical trials | monocentric | A | Dr. Raphael Knaier | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.08.2023 | |||||
| 2023-01274 | Project 2011 - ReCare: A prospective observational cohort on high-dose re-irradiation (E2-RADIatE cohort) | non clinical, involving persons | multicentric | A | Dr. Matthias Guckenberger | EORTC |
UniversitaetsSpital Zurich, Zurich Inselspital, Bern Reseau Hospitalier Neuchatelois - RHNe - La Chaux de Fonds (1462), La Chaux-de-Fonds |
Kantonale Ethikkommission Zürich | Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 10.10.2023 | |||||
| 2023-01273 | Electrocardiographic and smartphone photoplethysmographic heart rate variability in depressed patients and healthy individuals: An observational study | non clinical, involving persons | monocentric | A | Prof. Dr. med. Sebastian Olbrich | Psychiatrische Universitätsklinik Zürich |
Psychiatric Hospital, University of Zurich, Zürich |
Kantonale Ethikkommission Zürich | 24.11.2023 | ||||||
| 2023-01272 | Placebo-controlled Investigation of the Acute and Post-acute Effects of Lysergic Acid Diethylamide (LSD) in Healthy Elderly Subjects | clinical trial | other clinical trials | monocentric | B | Prof. Gregor Hasler | Universität Fribourg |
University of Fribourg, Fribourg |
Kantonale Ethikkommission Bern | 23.10.2023 | |||||
| 2023-01271 | Étude qualitative sur les attentes et représentations de patients confrontés aux enjeux de la surmédicalisation | non clinical, involving persons | monocentric | A | Dr Gaspard Aebischer | Institut universitaire de médecine de famille |
Institut universitaire de médecine de famille, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 10.08.2023 | ||||||
| 2023-01270 | Retrospektive Analyse von Brustgewebe, Brustkrebs, Brustkrebs-Metastasen, sowie des Tumor- und Metastasen-Mikroenvironments bei Brustkrebs-Patientinnen und -Patienten | personal data/biological material | monocentric | Prof. Dr. med. Walter Weber | University Hospital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 11.08.2023 | |||||||
| 2023-01269 | Phase 2/3 Randomized Study of Tebentafusp as Monotherapy and in Combination with Pembrolizumab Versus Investigator’s Choice in HLA-A*02:01-positive Participants with Previously Treated Advanced Melano More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. med. Reinhard Dummer | Immunocore, Ltd. |
Universitätsspital Zürich, Zürich Kantonsspital St. Gallen, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS) | 13.10.2023 | |||
| 2023-01268 | A Phase 1/2 First-in-Human Study of the Safety and Efficacy of IMC-F106C as a Single Agent and in Combination with Checkpoint Inhibitors in HLA-A*02:01-Positive Participants with Advanced PRAME-Positi More ... | clinical trial | drugs | phase 1/2 | multicentric | C | Prof. Dr. med. Reinhard Dummer | Immunocore, Ltd. |
Universitätsspital Zürich, Zürich Universitätsspital Basel, Basel University of Lausanne (CHUV), Lausanne |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.01.2024 | |||
| 2023-01266 | TRI0363 - Evolution of Anti-Drug Responses in XXB750 First in Human Study | personal data/biological material | monocentric | Vanessa Cornacchione, PhD | Novartis Pharma AG - NIBR |
Novartis Pharma AG, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 06.07.2023 | |||||||
| 2023-01265 | BO44426 - A PHASE Ib/II, OPEN-LABEL, MULTICENTER STUDY EVALUATING THE SAFETY, ACTIVITY, AND PHARMACOKINETICS OF DIVARASIB IN COMBINATION WITH OTHER ANTI-CANCER THERAPIES IN PATIENTS WITH PREVIOUSLY UN More ... | clinical trial | drugs | phase 1/2 | multicentric | C | Dr. med. David König | Roche Pharma (Schweiz) AG |
Universitätsspital Basel, Basel Insel Gruppe AG, Inselspital Bern, Bern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern | 21.09.2023 | |||
| 2023-01264 | Computer Navigated Drainage of Rouvière Lymph Node Abscess – Comparison of CAS vs Conventional Technique | personal data/biological material | monocentric | PD Dr. med. Patrick Dubach | Universitätsklinik für Hals-, Nasen- und Ohrenkrankheiten, Kopf- und Halschirurgie |
Inselspital Bern, Klinik für HNO, Kopf- und Halschirurgie, Bern |
Kantonale Ethikkommission Bern | 05.10.2023 | |||||||
| 2023-01263 | Swiss 2024 Fever Monitoring Study. An investigator initiated double-blinded, randomized controlled multiple crossover superiority trial on continuous fever monitoring with or without fever alerts in p More ... | clinical trial | other clinical trials | monocentric | A | Dr. Dr. Eva Brack | Inselspital Bern |
Kinderklinik Bern, Inselspital, Bern |
Kantonale Ethikkommission Bern | 08.09.2023 | yes | ||||
| 2023-01262 | Regulation of Stress and Early-life Brain Development | non clinical, involving persons | monocentric | A | Professor Ulrike Rimmele | University of Geneva |
University of Geneva, Geneva |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 15.01.2024 | yes | |||||
| 2023-01261 | Markers for invasive and aggressive behavior in meningiomas | personal data/biological material | multicentric | MD PD MER, Mahmoud Messerer | CHUV - NCHD |
CHUV, Lausanne Cantonal Hospital Aarau, Aarau |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Ethikkommission Nordwest- und Zentralschweiz EKNZ | 21.08.2023 | ||||||
| 2023-01260 |
Gynäkopsychiatrische Begleitung im Übergang zur Elternschaft – eine Untersuchung bedeutsamer Schutz- und Risikofaktoren unter Einbezug von Partner:innen und interdisziplinärem Netzwerk |
non clinical, involving persons | monocentric | A | Dr. phil. Fabienne Forster | Psychiatrie St. Gallen |
Pschiatrie St. Gallen, Wil |
Ethikkommission Ostschweiz (EKOS) | 26.10.2023 | ||||||
| 2023-01259 | A Phase 3 Randomized, Open-Label, Multicenter Study of Zanubrutinib (BGB-3111) Plus Anti-CD20 Antibodies Versus Lenalidomide Plus Rituximab in Patients With Relapsed/Refractory Follicular or Marginal More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr Gaëlle Rhyner Agocs | Beigene Ltd. |
Hopital Fribourgeois, Fribourg Réseau hospitalier Neuchatelois, La Chaux-de-Fonds |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 05.03.2024 | |||