| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2022-00605 | SERENA-4: A Randomised, Multicentre, Double-Blind, Phase III Study of AZD9833 (an Oral SERD) plus Palbociclib versus Anastrozole plus Palbociclib for the Treatment of Patients with Estrogen Receptor-P More ... | clinical trial | drugs | phase 3 | multicentric | C | PD Dr. med Marcus Vetter | AstraZeneca AB |
Kantonsspital Baselland, Onkologie Hämatologie & Immuntherapie, 4410 Liestal Inselspital, Universitätsspital Bern, Freiburgstrasse 15, 3010 Bern Brust-Zentrum Zürich, Onkologie, Zürich |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | Kantonale Ethikkommission Bern, Kantonale Ethikkommission Zürich | 20.07.2022 | |||
| 2022-00604 | Controllability and the interoception of breathing” (CITRO) | non clinical, involving persons | monocentric | A | Dr. Sandra Iglesias, PhD | UZH & ETHZ, Institut für Biomedizinische Technik, Translational Neuromodeling Unit |
Translational Neuromodeling Unit, Zurich |
Kantonale Ethikkommission Zürich | 06.05.2022 | ||||||
| 2022-00603 | SASCIA - Phase III postneoadjuvant study evaluating Sacituzumab Govitecan, an Antibody Drug Conjugate in primary HER2-negative breast cancer patients with high relapse risk after standard neoadjuvant More ... | clinical trial | drugs | phase 3 | multicentric | C | Dr. med. Ursina Zürrer | GBG (German Breast Group) |
Kantonsspital Winterthur, Winterthur Brustzentrum, University Hospital Basel, Basel Kantonsspital St. Gallen, St. Gallen Brustzentrum Zürich, Zürich Kantonsspital Graubünden, Chur |
Kantonale Ethikkommission Zürich | Ethikkommission Nordwest- und Zentralschweiz EKNZ, Ethikkommission Ostschweiz (EKOS), Kantonale Ethikkommission Zürich | 24.06.2022 | |||
| 2022-00602 | A brief report of an interesting bone marrow finding in systemic mastocytosis | personal data/biological material | monocentric | Dr Vasiliki Papadopoulou | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 07.04.2022 | |||||||
| 2022-00597 | Evaluation of molecular and Next Generation Sequencing approaches for SARS-CoV-2 identification and characterization in clinical samples | personal data/biological material | monocentric | PD Dr. Alban Ramette | University of Bern |
University of Bern, Bern |
Kantonale Ethikkommission Bern | 15.09.2022 | |||||||
| 2022-00595 | Streptococcus bovis bacteraemia : metastatic malignancies in the gut are also a gateway | personal data/biological material | monocentric | Sylvain Meylan | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 19.04.2022 | |||||||
| 2022-00594 | Fontan-associated Liver Disease (FALD): laboratory, clinical, histological and imaging characteristics of a Swiss, single-centre, adult cohort | personal data/biological material | monocentric | Prof. Annalisa Berzigotti | UVCM, Hepatology |
UVCM, Inselspital, Bern |
Kantonale Ethikkommission Bern | 09.12.2022 | |||||||
| 2022-00593 | Evaluation of interactions between conventional and complementary medicine in healthcare circuits in Switzerland: a pilot observational study using health insurance billing data. | personal data/biological material | monocentric | Prof / Idris / Guessous | Hopitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 10.05.2022 | |||||||
| 2022-00592 | Visual Symptoms in Postural Tachycardia Syndrome | non clinical, involving persons | monocentric | A | Prof. Dr. med. Werner Z`Graggen | Universitätsklinik für Neurochirurgie und Neurologie |
Universitätsklinik für Neurochirurgie und Neurologie, Bern |
Kantonale Ethikkommission Bern | 24.06.2022 | ||||||
| 2022-00589 | Non-destructive assessment of articular cartilage: Can the device Arthro-BST be used safely and reliably under sterile conditions in hip and knee arthroplasty? | non clinical, involving persons | monocentric | A | Prof. Dr. med Moritz Tannast | HFR Fribourg - Cantonal Hospital |
HFR Fribourg - Cantonal Hospital, Fribourg |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.04.2022 | ||||||
| 2022-00588 | Smartphone app-assisted discontinuation of PPI – an interprofessional pilot study | non clinical, involving persons | monocentric | A | PD DR Isabelle Arnet | University of Basel |
University of Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 10.06.2022 | ||||||
| 2022-00587 | Role of telomere length analysis in patients with vascular liver disease, idiopathic non cirrhotic portal hypertension, and cryptogenic cirrhosis | non clinical, involving persons | multicentric | A | Dre / Christinet / Montserrat Fraga | CHUV |
Centre hospitalier universitaire vaudois, Lausanne Ente Ospedaliero Cantonale, Lugano |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | Comitato etico cantonale Ticino | 06.10.2022 | |||||
| 2022-00586 | Adolescence et médiation thérapeutique par le jeu de rôle | non clinical, involving persons | monocentric | A | Dr Corentin Boulay | Université de Lausanne |
Université de Lausanne, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 09.09.2022 | yes | |||||
| 2022-00585 | Skeletal Muscle Health in Diabetes and Aging. | non clinical, involving persons | monocentric | B | PD Dr med Jan Krützfeldt | University Hospital of Zurich |
University Hospital of Zurich, Zurich |
Kantonale Ethikkommission Zürich | 21.06.2022 | ||||||
| 2022-00584 | Wearable sensors for delirium detection at an early stage (WeSen_delirium) – an exploratory study | non clinical, involving persons | monocentric | A | PD Dr. Martina Kleber | Department of Internal Medicine, University Hospital of Zurich |
University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 15.07.2022 | ||||||
| 2022-00583 | The Change of biological and biomechanical properties of the Ligamentum flavum in relation to age and degeneration of the spine | deceased persons | monocentric | Prof. Dr. med. Mazda Farshad | Universitätsklinik Balgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 22.04.2022 | |||||||
| 2022-00582 | Enucleation of the Prostate in Thurgau (EPiT) – Retro- and Prospective Quality Assessment and Follow Up | personal data/biological material | monocentric | Prof. Dr. med. Thomas Herrmann |
Urologie STGAG, Frauenfeld |
Ethikkommission Ostschweiz (EKOS) | 05.04.2022 | ||||||||
| 2022-00581 | Catamnèse de familles aux prises avec un processus d'emprise : de l'expertise psychiatrique à leur évolution post-jugement | personal data/biological material | monocentric | Mme GUILLEN-MELCHIORRE Maud | CURML - HUG |
CPPL-CURML-HUG, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 20.07.2022 | |||||||
| 2022-00579 | Développement d’un processus de mise en œuvre des pratiques collaboratives interprofessionnelles en partenariat avec les patient·e·s et les proches dans un centre de thérapies pour les enfants de 0-5 More ... | non clinical, involving persons | monocentric | A | Prof. Christian Voirol | Association genevoise d'accompagnement thérapeutique de l'enfant (Agathe) |
Centre AGAThE (ss mandat de la HE-Arc Santé), Carouge |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.07.2022 | yes | |||||
| 2022-00578 | Randomized clinical pilot study investigating the effect of Lactobacillus reuteri on subgingival biofilm formation on healing abutments and inflammatory status of surrounding peri-implant tissues | clinical trial | other clinical trials | monocentric | A | Dr. med. dent. (HU) Tobias M. Janson | Clinic of Conservative and Preventive Dentistry University of Zurich, Center of Dental Medicine |
Clinic of Conservative and Preventive Dentistry University of Zurich, Center of Dental Medicine, Zurich |
Kantonale Ethikkommission Zürich | 02.08.2022 | |||||