| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-D0099 | Uro-catheter vacuum-induced uterine tamponade (U-CaVIT) versus standard of care for prevention of atonic postpartum hemorrhage after cesarean section in high-risk women: a monocentric randomized-contr More ... | clinical trial | medical devices | monocentric | C1 | Prof. Dr. med. Christian Haslinger | UniversitätsSpital Zürich |
Department of Obstetrics / University Hospital Zurich, Zürich |
Kantonale Ethikkommission Zürich | 21.01.2025 | |||||
| 2024-D0098 | Analysis of electrocochleographic signals during speed-controlled cochlear implant electrode array insertion in a non-randomized controlled trial | clinical trial | medical devices | monocentric | C2 | Prof. Dr. med. Alexander Huber | Dept. of Otorhinolaryngology, Head&Neck Surgery University Hospital Zurich |
Department of Otorhinolaryngology, Head & Neck Surgery, University Hospital Zurich, Zürich |
Kantonale Ethikkommission Zürich | 20.12.2024 | |||||
| 2024-D0095 | 20220028 PS_Clinical Performance Study Plan for CD23 IHC Clinical Trial Assay for Combined Study with Amgen Clinical Trial 20220028 | clinical trial | in vitro diagnostic medical devices IVD-MD | multicentric | C2 | Martina Imbimbo | AMGEN |
Istituto Oncologico della Svizzera Italiana, Bellinzona HOCH Health Ostschweiz, Rorschacher Strasse 95 |
Comitato etico cantonale Ticino | Ethikkommission Ostschweiz (EKOS) | 20.11.2024 | ||||
| 2024-D0094 | Rotator Cuff Tendon Repair With FiberLocker System Patch Augmentation: A Prospective, Single-Arm, Non-Randomized, Pilot Study | clinical trial | medical devices | monocentric | C2 | Prof. Dr. med. Karl Wieser | ZuriMED Technologies AG |
Balgrist University Hospital, Zürich |
Kantonale Ethikkommission Zürich | 25.04.2025 | |||||
| 2024-D0093 | Pharmacokinetics and safety of Sinovial HL® 3.2% solution after single intra-articular injection in knee of healthy men and women | clinical trial | medical devices | monocentric | C1 | Dr Milko Radicioni | IBSA Institut Biochimique S.A. |
CROSS Research S.A. Phase I Unit, Arzo |
Comitato etico cantonale Ticino | 22.10.2024 | |||||
| 2024-D0091 | EASEE® System - Long-term registry on Epilepsy Evolution in subjects treated with transcranial focal cortex stimulation | clinical trial | medical devices | monocentric | A1 | Prof. Pierre Mégevand | Precisis GmbH |
Hôpitaux universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 13.01.2025 | |||||
| 2024-D0090 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Optune® (TTFields, 200 kHz) Concomitant with Maintenance Temozolomide and Pembrolizumab Versus Optune® Concomitant with Maintenance Tem More ... | clinical trial | combination drugs/devices | multicentric | C1 | Prof. Dr. med. Michael Weller | Novocure GmbH |
Universitätsspital Zürich, Zürich Universitätsspital Basel, Medical Onkologie Service de neurologie, Centre hospitalier universitaire vaudois (CHUV) R |
Kantonale Ethikkommission Zürich | Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD), Ethikkommission Nordwest- und Zentralschweiz EKNZ | 20.12.2024 | ||||
| 2024-D0089 | Feasibility and cost of robot-assisted upper limb rehabilitation with different levels of supervision: an interventional study | clinical trial | medical devices | monocentric | C2 | Dr. med. Daria Dinacci | ETH Zurich |
Clinica Hildebrand Centro di riabilitazione Brissago, Brissago |
Comitato etico cantonale Ticino | 03.02.2025 | |||||
| 2024-D0088 | Unraveling the impact of Radiofrequency in liver surgery: the key to decrease local recurrence? | clinical trial | medical devices | monocentric | A1 | PD Dr. Dr. med. Lukasz Filip Grochola | Hospital del Mar |
Kantonsspital Winterthur, Klinik für Viszeral- und Thoraxchirurgie, Winterthur |
Kantonale Ethikkommission Zürich | 22.11.2024 | |||||
| 2024-D0087 | Evaluation of soft tissue and organ lesions using Multispectral Optoacoustic Tomography (MSOT) with comparison to traditional imaging techniques | clinical trial | medical devices | monocentric | A1 | Prof. Dr. Thomas Frauenfelder | University Hospital Zurich |
Institute for Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 08.04.2025 | |||||
| 2024-D0086 | Pilot project of an intra-uterine manipulator with integrated, scalable light source with image processing system for correction of uterine scar dehiscence (niche) with the DaVinci® robot | clinical trial | medical devices | monocentric | C2 | Prof. Dr. med. Cornelia Betschart | Klinik für Gynäkologie und Geburtshilfe, Universitätsspital Zürich |
Klinik für Gynäkologie Universitätsklinik Zürich, Zürich |
Kantonale Ethikkommission Zürich | 04.02.2025 | |||||
| 2024-D0085 | Effects on Acute Respiratory Failure of Early High Flow Oxygen Therapy compared with Conventional Oxygen Therapy in Older People with Do-Not Intubation Order in Hypoxemic Acute Respiratory Disease: a More ... | clinical trial | medical devices | monocentric | A1 | Dr Clémence Cuvelier | Hôpitaux Universitaire de Genève |
Hôpitaux Universitaire de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 20.01.2025 | |||||
| 2024-D0083 | Comparison of Gastric Air Insufflation and Ventilation between two Laryngeals masks (LMA): Igel and Igelplus | clinical trial | medical devices | monocentric | A1 | Prof. Dr. med. Christoph J. Konrad | Luzerner Kantonsspital |
Klinik für Anästhesie, Luzerner Kantonsspital, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 09.10.2024 | |||||
| 2024-D0082 | Study on preliminary safety and efficacy of epidural electrical stimulation to manage lower urinary tract dysfunction after spinal cord injury | clinical trial | medical devices | monocentric | C1 | Prof. Dr. MD. Jocelyne Bloch | EPFL |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 19.02.2025 | |||||
| 2024-D0080 | The brain-heart-gut connection (BHG-CONNECT): Targeting the frontal-vagal pathway to personalize noninvasive brain stimulation | clinical trial | medical devices | monocentric | A1 | Anna-Katharine Brem | Universitäre Psychiatrische Dienste (UPD) |
University Hospital of Psychiatry and Psychotherapy Bern, Bern |
Kantonale Ethikkommission Bern | 22.11.2024 | |||||
| 2024-D0078 | Clinical outcomes following dual-light photodynamic therapy administered daily during supportive periodontal therapy: an 8-week randomized clinical trial | clinical trial | medical devices | monocentric | A1 | Prof. Christoph Ramseier | University of Bern |
University of Bern, Berne |
Kantonale Ethikkommission Bern | 12.11.2024 | |||||
| 2024-D0077 | A multi-center randomized controlled trial first in human study to assess the feasibility and preliminary safety data of adjunctive treatment with the HemoSystem REBOOT in critically ill patientS wiTh More ... | clinical trial | medical devices | multicentric | C2 | Prof. Dr. Jörg Schefold | hemotune AG |
University Hospital Bern, Inselspital, Bern University Hospital Zurich, Institut für Intensivmedizin, Rämistrasse 100 |
Kantonale Ethikkommission Bern | Kantonale Ethikkommission Zürich | 27.09.2024 | ||||
| 2024-D0075 | Feasibility study of a therapy for people with types 1 or 2 diabetes based on an Adaptive Bolus-Basal Algorithm (ABBA) | clinical trial | medical devices | monocentric | C2 | Doctor Karim Gariani | Hôpitaux Universitaires de Genève |
Hôpitaux Universitaires de Genève, Genève |
Commission Cantonale d'éthique de la recherche Genève (CCER) | 16.12.2024 | |||||
| 2024-D0074 | Pre-market multicentric cross-sectional clinical investigation of MAIA microperimeter device: mesopic normative database collection | clinical trial | medical devices | monocentric | C2 | PD Dr. med. Kristina Pfau | Centervue |
Universitätsspital Basel, Augenklinik, Basel, Switzerland |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 25.09.2024 | |||||
| 2024-D0073 | A Phase I Clinical Study on Feasibility and Toxicity of LINAC-based Flash Radiotherapy for Palliative Treatment of Skin Lesions of Malignant Melanomas (Flash-Skin I) | clinical trial | medical devices | monocentric | C2 | PD Dr. med. Jens von der Grün | Universität Zürich |
Universitätsspital Zürich, Zürich |
Kantonale Ethikkommission Zürich | 08.11.2024 | |||||