BASEC ID Project title Type of project Type of clinical trial Study phase (clinical trials only) multi- / monocentric Category Principal investigator Sponsor Investigational sites Lead EC Local EC(s) Approval date Minors Study Ended
2023-02051 Fecal microbiome signature of multi-strain probiotics supplementation in children and adolescents with inflammatory bowel disease - a pilot study clinical trial other clinical trials monocentric A PD Dr. med. Christiane Sokollik Universitätsspital für Kinderheilkunde, Bern
Kantonale Ethikkommission Bern 12.02.2024 yes
2023-02050 An Open-Label Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of OMS906 in Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) clinical trial drugs phase 2 monocentric C Dr Mathilde Gavillet Omeros Corporation Lausanne University Hospital CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 19.02.2024
2023-02047 A multi-center, multi-country prospective observational study of patients
initiating T-DXd in the first or second treatment line for HER2+, and HER2-low unresectable and/or metastatic breast cancer
non clinical, involving persons multicentric A Prof. Dr. med. Christian Kurzeder AstraZeneca Universitätsspital Basel, Basel
Inselspital, Bern
Kantonsspital Baselland, Liestal
Hôpital Riviera Chablais, Rennaz
Ethikkommission Nordwest- und Zentralschweiz EKNZ Ethikkommission Nordwest- und Zentralschweiz EKNZ, Kantonale Ethikkommission Bern, Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 11.01.2024
2023-02046 Outcomes of patients with Oligometastatic Non-Small Cell Lung Cancer (NSCLC) treated with first line Immuno-/ or Chemoimmunotherapy personal data/biological material monocentric Prof. Martin Früh KSSG; Medical Oncology St. Gallen KSSG, Medical Oncology, St. Gallen
Ethikkommission Ostschweiz (EKOS) 14.12.2023
2023-02045 Human-derived TDP-43 intrabodies to restore TDP-43 function in ALS deceased persons monocentric Dr Nikole Zuniga Mabylon AG Mabylon, Schlieren
Kantonale Ethikkommission Zürich 12.01.2024
2023-02044 Transition de la pédiatrie à la médecine adulte lors du suivi des patients atteints d'une maladie inflammatoire de l'intestin non clinical, involving persons monocentric A Pr Andreas Nydegger CHUV - DFME - Pédiatrie CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 13.02.2024
2023-02043 Effect of modulating pendular mechanism and step-to-step transition using a biofeedback system on energetics and mechanics of walking in healthy individual non clinical, involving persons monocentric A MER - PhD /Davide/Maltesta ISSUL - UNIL UNIL- ISSUL, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 14.12.2023
2023-02041 Analgesic efficacy of IPACK versus selective tibial nerve block in patients scheduled for total knee arthroplasty under spinal anaesthesia with an adductor canal block: a randomised controlled double- More ... clinical trial other clinical trials monocentric A Prof Eric Albrecht CHUV - Anesthésiologie Chuv, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 11.01.2024
2023-02038 Etude rétrospective des patients implantés d’un neurostimulateur de l’hypoglosse pour apnée du sommeil au CHUV personal data/biological material monocentric Dr Karma Lambercy CHUV - ORL CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 22.02.2024
2023-02036 Evaluation of up-to-date information needs and expectations of UC patients non clinical, involving persons monocentric A Valérie Pittet Unisanté - DESS Unisanté, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 08.02.2024
2023-02035 Assessing the role of prolonged close contact in the spread of respiratory viral infections in schools non clinical, involving persons monocentric A Prof. Lukas Fenner Institute of Social and Preventive Medicine (ISPM) ISPM, Bern
Kantonale Ethikkommission Bern 18.12.2023 yes
2023-02033 FORM: Fetal Phenomics to unravel the correlation between phenotype and genotype in prenatal malformations embryos/fetuses monocentric Prof.Dr.med. Isabel Filges Medizinische Genetik, Institut für Medizinische Genetik und Pathologie, niversitätsspital Basel Medical Genetics, University Hospital Basel, Basel
Ethikkommission Nordwest- und Zentralschweiz EKNZ 20.12.2023
2023-02032 Impacte de la Gastric Peroral Endoscopic Myotomy (GPOEM) sur la fréquence des selles chez les patients atteints de gastroparésie et de trouble du transit chronique. personal data/biological material monocentric Dr. Sébastien Godat CHUV - Gastro-entérologie CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 08.01.2024
2023-02030 Exploring the suitability of ants as diagnostic tools for premature rupture of amniotic membranes personal data/biological material monocentric Dr Hélène LEGARDEUR CHUV - DFME CHUV, Lausanne
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) 16.01.2024
2023-02028 Validation of the European consensus for the biomarker-based diagnosis of neurocognitive disorders: an investigator-initiated sponsored study (EuroValiCo) personal data/biological material monocentric Pr. Giovanni Frisoni HUG HUG, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 08.01.2024
2023-02026 Retrospective analysis of weight gain upon adjuvant anti-hormonal treatment in patients diagnosed with Hormonal-receptor positive early breast cancer personal data/biological material monocentric Dr Julian Wampfler Universitätsklinik für Medizinische Onkologie, Inselspital Universitätsklinik für Medizinische Onkologie, Inselspital, Bern
Kantonale Ethikkommission Bern 16.01.2024
2023-02024 PrEcision medicine in the management of cardiovascular surgery associated AKI - PEAK: a prospective observational cohort study non clinical, involving persons monocentric A Prof. Dr. med. Uyen Huynh-Do Inselspital, Universitätsspital Bern Inselspital, Bern
Kantonale Ethikkommission Bern 22.01.2024
2023-02020 A Comparison of MEG and hd-EEG brain source localization non clinical, involving persons monocentric A Professor Christoph Michel University of Geneva University of Geneva, Geneva
Commission Cantonale d'éthique de la recherche Genève (CCER) 10.01.2024
2023-02017 Did a prolonged exposure to an echocardiographically hemodynamically significant ductus arteriosus in infants <28 0/7 gestational age result in symptoms of decreased organ perfusion? personal data/biological material monocentric Dr. med. David Glauser University Hospital of Zurich University Hospital of Zurich, Zurich
Kantonale Ethikkommission Zürich 27.02.2024
2023-02016 Correlation of AI-supported volumetry of aortic valve calcification with calcific load of the aorta. personal data/biological material monocentric Prof. Dr. med. Tilo Niemann Kantonsspital Baden AG Kantonsspital Baden AG, Baden
Ethikkommission Nordwest- und Zentralschweiz EKNZ 24.11.2023