| BASEC ID | Project title | Type of project | Type of clinical trial | Study phase (clinical trials only) | multi- / monocentric | Category | Principal investigator | Sponsor | Investigational sites | Lead EC | Local EC(s) | Approval date | Minors | Study Ended | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-02143 |
Effect of permissive hypercapnia on intracranial pressure in patients undergoing robotic-assisted radical prostatectomy in Trendelenburg position, a Randomized Clinical Trial |
clinical trial | other clinical trials | monocentric | A | Dr. phil. Wilhelms Schellekens | Department of Anesthesiology, KSA |
KSA, Aarau |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 22.01.2026 | |||||
| 2025-02142 | Quantification of the Keyhole Concept in Cranial Neurosurgery | clinical trial | other clinical trials | monocentric | A | Dr. Jonathan Rychen | Universitätsspital Basel |
University Hospital Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 01.12.2025 | |||||
| 2025-02140 |
Use of clinical and radiological data for research on palmar plate, pulley, and ligament injuries of the fingers |
personal data/biological material | monocentric | Dr. med. Mauro Maniglio | Universitätsklinik Bvalgrist |
Universitäsklinik Balgrist, Zurich |
Kantonale Ethikkommission Zürich | 06.02.2026 | |||||||
| 2025-02139 | Retrospective Studies of 3D-guided patient-specific instrumentation (PSI) with the CARD system for corrective osteotomies of the upper limb | personal data/biological material | monocentric | Dr. med. Mauro Maniglio | Universitätsklinik Bvalgrist |
Universitätsklinik Balgrist, Zürich |
Kantonale Ethikkommission Zürich | 09.01.2026 | |||||||
| 2025-02138 | Longitudinal assessment of the Edinburgh Cognititve and Behavioural Amyotrophic Lateral Sclerosis screen (ECAS), version A, B and C | non clinical, involving persons | monocentric | A | Oleksandra Hoptar | HOCH Health Ostschweiz, Kantonsspital St. Gallen Kantonsspital St. Gallen, Muskelzentrum/ALS Clinic |
HOCH Health Ostschweiz, Kantonsspital St. Gallen, Muskelzentrum/ALS Clinic, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 23.10.2025 | ||||||
| 2025-02137 | A 52-week, Multicenter, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study of Nemolizumab in Adult Patients with Systemic Sclerosis | clinical trial | drugs | phase 2 | multicentric | C | PD Dr. Dr. med. Muriel Elhai | Galderma S.A. |
Universitätsspital Zürich, Zurich HOCH Health Ostschweiz, Kantonsspital St. Gallen, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS) | 09.01.2026 | |||
| 2025-02133 | Clinicogenomic prediction modelling in pancreatic cancer – an explorative retrospective cohort study | personal data/biological material | monocentric | Dr. med. Christoph Kümmerli | Clarunis Universitäres Bauchzentrum Basel |
Clarunis Universitäres Bauchzentrum Basel, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 04.12.2025 | |||||||
| 2025-02131 |
Stress shielding patterns and risk factors in anatomic total shoulder arthroplasty |
personal data/biological material | monocentric | PhD Dr. med. Matthijs Jacxsens | HOCH Health Ostschweiz |
HOCH Health Ostschweiz, St. Gallen |
Ethikkommission Ostschweiz (EKOS) | 23.10.2025 | |||||||
| 2025-02130 | Retrospektive Evaluation dedizierter, mit Beschleunigung akquirierter und mit Hilfe künstlicher Intelligenz rekonstruierter, klinisch routinemässig eingesetzter MR-Sequenzen bei Kindern | personal data/biological material | monocentric | PD Dr. Selma Sirin | Kinderspital Zürich - Eleonorenstiftung |
Kinderspital Zürich - Eleonorenstiftung, Zürich |
Kantonale Ethikkommission Zürich | 18.12.2025 | |||||||
| 2025-02127 |
Tige Fémorale Modulaire, Conique, Cannelée, Non Cimentée (Restoration Stryker®) avec Cupule Hémisphérique à Double Mobilité (Symbol, Dedienne Santé ®) dans les révisions de PTH: Survie d’implant à More ... |
personal data/biological material | monocentric | Prof. Julien Wegrzyn | CHUV |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.10.2025 | |||||||
| 2025-02125 | Multivendor validation of AI tools for pediatric musculoskeletal radiographic measurements | personal data/biological material | monocentric | PD Dr. med. Michelle Seiler | University Children's Hospital Zurich |
University Children's Hospital Zurich, Zurich |
Kantonale Ethikkommission Zürich | 23.01.2026 | |||||||
| 2025-02123 | Effect of Cochlear Implant Stimulation on Spatial Orientation in Adult Users | clinical trial | other clinical trials | monocentric | A | Prof. Dr. med. Georgios Mantokoudis | Inselspital Bern |
Universitätsklinik für Hals-, Nasen- und Ohrenkrankheiten, Kopf- und Halschirurgie, Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 20.01.2026 | |||||
| 2025-02120 | Vacuum Bell Therapy as a Non-Surgical Alternative for Pectus Excavatum: Real-World Experience | personal data/biological material | monocentric | Dr. med. Konstantinos Gioutsos | Thoracic Surgery |
Inselspital, Bern University Hospital, Bern |
Kantonale Ethikkommission Bern | 14.11.2025 | |||||||
| 2025-02116 | Adaptive, Phase 2/3, Randomized, Double-Blind Trial Investigating the Efficacy and Safety of Visugromab versus Placebo in Patients with Cancer-associated Cachexia (Visugromab in Cachexia International More ... | clinical trial | drugs | phase 2 | multicentric | C | Prof. Dr. David Blum | CatalYm GmbH |
Universitäts Spital Zürich, Zürich HOCH Health Ostschweiz, St. Gallen |
Kantonale Ethikkommission Zürich | Ethikkommission Ostschweiz (EKOS) | 20.01.2026 | |||
| 2025-02114 | Tracheostomy after bilateral lung transplantation: timing impact on short- and long-term outcomes in a retrospective single center cohort | personal data/biological material | monocentric | Prof. Thorsten Krueger | CHUV - Chirurgie Thoracique |
CHUV, Lausanne |
Commission cantonale d'Éthique de la Recherche sur l'être humain Vaud (CER-VD) | 27.10.2025 | |||||||
| 2025-02113 | Retrospektive Outcome-Analyse erwachsener Patienten nach allogener Stammzelltransplantation am Luzerner Kantonsspital 2014-2023 | personal data/biological material | monocentric | Lucas Simeon | LUKS Spitalbetriebe AG |
Luzerner Kantonsspital LUKS, Luzern |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 24.11.2025 | |||||||
| 2025-02109 | Pacing Advancements with Cost and Experience VALuation for Unified Patient-Led Clinical Evidence - the PACEVALUE Study | non clinical, involving persons | monocentric | A | Prof. Dr. Dr. med. Andreas Häberlin | Inselspital Bern |
Inselspital Bern, Bern |
Kantonale Ethikkommission Bern | 03.02.2026 | ||||||
| 2025-02108 | FEASIBILITY OF SUBJECTIVE REFRACTION MEASUREMENT WITH LIGHTFIELD TECHNOLOGY – STUDY II | non clinical, involving persons | monocentric | A | Prof. Dr. Daniela Nosch | Institut für Optometrie, FHNW |
Institut für Optometrie, Hochschule für Technik, FHNW, 4600 Olten |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 19.11.2025 | ||||||
| 2025-02106 | SINERGIC : a Swiss Interprofessional NEtwork for ReviewinG Inapropriate medication in outpatient Care - pilot study | clinical trial | other clinical trials | monocentric | A | Professor Alice Panchaud | BIHAM |
Institute of Primary Health Care (BIHAM), Bern |
Kantonale Ethikkommission Bern | 10.12.2025 | |||||
| 2025-02102 | Vergleich robotischer und offener Gastrektomie hinsichtlich des Outcomes der Anastomosentechnik – eine retrospektive Kohortenstudie (2016–2025) (Masterarbeit) | personal data/biological material | monocentric | Dr. Marko Kraljevic | Clarunis |
Clarunis, Basel |
Ethikkommission Nordwest- und Zentralschweiz EKNZ | 03.11.2025 | |||||||